FN Archimer Export Format PT J TI Does broodstock nutritional history affect the response of progeny to different first-feeding diets? A whole-body transcriptomic study of rainbow trout alevins BT AF LAZZAROTTO, Viviana CORRAZE, Genevieve LARROQUET, Laurence MAZURAIS, David MEDALE, Francoise AS 1:1;2:1;3:1;4:2;5:1; FF 1:;2:;3:;4:PDG-RBE-PFOM-ARN;5:; C1 INRA, UR Nutr Metab Aquaculture 1067, Aquapole, St Pee Sur Nivelle, France. IFREMER, IRD, UBO, CNRS,LEMAR UMR 6539,ZI Pointe Diable,CS 10070, F-29280 Plouzane, France. C2 INRA, FRANCE IFREMER, FRANCE SI BREST SE PDG-RBE-PFOM-ARN UM LEMAR IN WOS Ifremer jusqu'en 2018 copubli-france copubli-p187 IF 3.706 TC 28 UR https://archimer.ifremer.fr/doc/00344/45552/46610.pdf https://archimer.ifremer.fr/doc/00344/45552/46611.pdf https://archimer.ifremer.fr/doc/00344/45552/46613.tif https://archimer.ifremer.fr/doc/00344/45552/46614.tif https://archimer.ifremer.fr/doc/00344/45552/46615.tif https://archimer.ifremer.fr/doc/00344/45552/46616.tif https://archimer.ifremer.fr/doc/00344/45552/46617.tif LA English DT Article DE ;Fish;Nutrition;Plant products;Fatty acids;Gene expression;Microarrays;Early stages AB The whole-body transcriptome of trout alevins was characterised to investigate the effects of long-term feeding of rainbow trout broodstock females a diet free of fishmeal and fish oil on the metabolic capacities of progeny. Effects were studied before first feeding and after 3 weeks of feeding diets containing different proportions of marine and plant ingredients. Feeding alevins plant-based diets resulted in lower fish body weight, irrespective of maternal nutritional history. No differences in whole-body lipids were found between treatments, and the tissue fatty acid profile strongly reflected that of the respective broodstock or first-feeding diets. We showed that the maternal diet history did not significantly affect expressions of any genes before the first feeding. Interestingly, we found an effect of maternal nutritional history on gene expression in alevins after 3 weeks of feeding. The major differences in the transcriptome of alevins from plant-based diet-fed females compared with those from commercial-fed females were as follows: (i) down-regulation of genes involved in muscle growth/contraction and (ii) up-regulation of genes involved in carbohydrate and energy metabolism related to the delay in growth/development observed with plant-based diets. Our findings also showed an effect of the first-feeding diets, irrespective of maternal nutritional history. Specifically, the introduction of plant ingredients resulted in the up-regulation of genes involved in amino acid/protein and cholesterol metabolism and in differences in the expressions of genes related to carbohydrate metabolism. Information gained through this study opens up avenues for further reduction of marine ingredients in trout diets, including the whole rearing cycle. PY 2016 PD JUL SO British Journal Of Nutrition SN 0007-1145 PU Cambridge Univ Press VL 115 IS 12 UT 000377973400001 BP 2079 EP 2092 DI 10.1017/S0007114516001252 ID 45552 ER EF