TY - JOUR T1 - Antimicrobial Compounds from Eukaryotic Microalgae against Human Pathogens and Diseases in Aquaculture A1 - Falaise,Charlotte A1 - Francois,Cyrille A1 - Travers,Marie-Agnes A1 - Morga,Benjamin A1 - Haure,Joel A1 - Tremblay,Rejean A1 - Turcotte,Francois A1 - Pasetto,Pamela A1 - Gastineau,Romain A1 - Hardivillier,Yann A1 - Leignel,Vincent A1 - Mouget,Jean-Luc AD - Univ Maine, CNRS, FR 3473, IUML Mer Mol Sante MMS, Ave O Messiaen, F-72085 Le Mans, France. AD - IFREMER, SG2M, LGPMM, Ave Mus Loup, F-17390 La Tremblade, France. AD - Univ Quebec, Inst Sci Mer Rimouski, 310 Ursulines, Rimouski, PQ G5L 3A1, Canada. AD - Univ Maine, CNRS, UMR 6283, IMMM, Ave O Messiaen, F-72085 Le Mans, France. UR - https://archimer.ifremer.fr/doc/00349/46052/ DO - 10.3390/md14090159 KW - biological activity KW - antimicrobial KW - antibacterial KW - antifungal KW - antiviral KW - biological activity KW - Haslea KW - microalgae KW - sustainable aquaculture N2 - The search for novel compounds of marine origin has increased in the last decades for their application in various areas such as pharmaceutical, human or animal nutrition, cosmetics or bioenergy. In this context of blue technology development, microalgae are of particular interest due to their immense biodiversity and their relatively simple growth needs. In this review, we discuss about the promising use of microalgae and microalgal compounds as sources of natural antibiotics against human pathogens but also about their potential to limit microbial infections in aquaculture. An alternative to conventional antibiotics is needed as the microbial resistance to these drugs is increasing in humans and animals. Furthermore, using natural antibiotics for livestock could meet the consumer demand to avoid chemicals in food, would support a sustainable aquaculture and present the advantage of being environmentally friendly. Using natural and renewable microalgal compounds is still in its early days, but considering the important research development and rapid improvement in culture, extraction and purification processes, the valorization of microalgae will surely extend in the future. Y1 - 2016/09 PB - Mdpi Ag JF - Marine Drugs SN - 1660-3397 VL - 14 IS - 9 ID - 46052 ER -