FN Archimer Export Format
PT J
TI High genetic diversity of     Vibrio cholerae     in the European lake Neusiedler See is associated with intensive recombination in the reed habitat and the long-distance transfer of strains
BT 
AF PRETZER, Carina
   DRUZHININA, Irina S.
   AMARO, Carmen
   BENEDIKTSDOTTIR, Eva
   HEDENSTROEM, Ingela
   HERVIO-HEATH, Dominique
   HUHULESCU, Steliana
   SCHETS, Franciska M.
   FARNLEITNER, Andreas H.
   KIRSCHNER, Alexander K. T.
AS 1:1,2;2:2;3:3;4:4;5:5;6:6;7:7;8:8;9:2,9;10:1,9;
FF 1:;2:;3:;4:;5:;6:PDG-RBE-SG2M-LSEM;7:;8:;9:;10:;
C1 Med Univ Vienna, Inst Hyg & Appl Immunol, Vienna, Austria.
   Vienna Univ Technol, Inst Chem Engn, Vienna, Austria.
   ERI BioTecMed Univ Valencia, Valencia, Spain.
   Univ Iceland, Fac Life & Environm Sci, Reykjavik, Iceland.
   Publ Hlth Agcy Sweden, Solna, Sweden.
   IFREMER, Plouzane, France.
   Austrian Agcy Hlth & Food Safety AGES, Vienna, Austria.
   Natl Inst Publ Hlth & Environm, Bilthoven, Netherlands.
   Interuniv Cooperat Ctr Water & Hlth, Vienna, Austria.
C2 UNIV VIENNA, AUSTRIA
   UNIV VIENNA, AUSTRIA
   UNIV VALENCIA, SPAIN
   UNIV ICELAND, ICELAND
   PUBL HLTH AGCY SWEDEN, SWEDEN
   IFREMER, FRANCE
   AGES, AUSTRIA
   RIVM, NETHERLANDS
   ICC, AUSTRIA
SI BREST
SE PDG-RBE-SG2M-LSEM
IN WOS Ifremer jusqu'en 2018
   copubli-europe
IF 4.974
TC 23
UR https://archimer.ifremer.fr/doc/00366/47756/47802.pdf
   https://archimer.ifremer.fr/doc/00366/47756/47803.pdf
LA English
DT Article
AB Coastal marine Vibrio cholerae populations usually exhibit high genetic diversity. To assess the genetic diversity of abundant V. cholerae non-O1/non-O139 populations in the Central European lake Neusiedler See, we performed a phylogenetic analysis based on recA, toxR, gyrB and pyrH loci sequenced for 472 strains. The strains were isolated from three ecologically different habitats in a lake that is a hot-spot of migrating birds and an important bathing water. We also analyzed 76 environmental and human V. cholerae non-O1/non-O139 isolates from Austria and other European countries and added sequences of seven genome-sequenced strains. Phylogenetic analysis showed that the lake supports a unique endemic diversity of V. cholerae that is particularly rich in the reed stand. Phylogenetic trees revealed that many V. cholerae isolates from European countries were genetically related to the strains present in the lake belonging to statistically supported monophyletic clades. We hypothesize that the observed phenomena can be explained by the high degree of genetic recombination that is particularly intensive in the reed stand, acting along with the long distance transfer of strains most probably via birds and/or humans. Thus, the Neusiedler See may serve as a bioreactor for the appearance of new strains with new (pathogenic) properties.
PY 2017
PD JAN
SO Environmental Microbiology
SN 1462-2912
PU Wiley-blackwell
VL 19
IS 1
UT 000393587200034
BP 328
EP 344
DI 10.1111/1462-2920.13612
ID 47756
ER

EF