FN Archimer Export Format PT J TI Lipophilic Toxin Profile in Mytilus galloprovincialis from the North Atlantic Coast of Morocco: LC-MS/MS and Mouse Bioassay Analyses BT AF BEN HADDOUCH, Asia AMANHI, Rachid AMZIL, Zouher TALEB, Hamib ROVILLON, Georges-Augustin ADLY, Farida LOUTFI, Mohammed AS 1:1;2:1;3:2;4:1;5:2;6:3;7:3; FF 1:;2:;3:PDG-ODE-DYNECO-PHYC;4:;5:PDG-ODE-DYNECO-PHYC;6:;7:; C1 Quality andSafety Department of MarineEnvironment,NationalFisheries Research Institute(INRH), Bd Sidi Abderrahmane, Ouled Jmal, 20050 Casablanca, Morocco IFREMER-Phycotoxins Laboratory, BP 21105, F-44311 Nantes, France Laboratory Biochemistry and MolecularBiology, Faculty of Science Ain Chock, Km 8, Route d’El Jadida,BP, 5366, Maârif. Casablanca. Morocco C2 INRH, MOROCCO IFREMER, FRANCE UNIV AIN CHOCK, MOROCCO SI NANTES SE PDG-ODE-DYNECO-PHYC TC 0 UR https://archimer.ifremer.fr/doc/00372/48342/48495.pdf LA English DT Article DE ;diarrheictoxins;lipophilic toxins;LC-MS/MS;mouse test;shellfish AB Forthe Moroccan Phycotoxins Monitoring that is part of theSafety of theCoastal Monitoring Network(RSSL),shellfish sampleswereharvestedfromdifferentlocations at NorthAtlantic of Morocco whereharmful algaeblooms were known to have occurred. Forallshellfishsamples found positive by themouse bioassay fordiarrheicshellfishpoisoning(DSP)toxins,liquid chromatography coupled to tandem massspectrometry(LC-MS-MS) in order to search thefollowinglipophilictoxins: okadaic acid (OA), dinophysistoxins(DTXs), pectenotoxins(PTXs), azaspiracids(AZAs), yessotoxins(YTXs), spirolides(SPXs) and gymnodimines (GYMs).Theresultsrevealeddifferentlipophilictoxinprofiles as a function of theshellfish sampling location. It has beennoticed that allthesamples contained OA and its derivativesnamed dinophysistoxins(DTXs). In addition, other lipophilictoxinswerefound in shellfishsamples:(YTXs), and pectenotoxins(PTX-2, PTX-2-seco-acid and 7- epi-PTX-2-seco-acid) on theNorthAtlantic coast .This paper reports on thefirstdetection of YTXs,PTXsGYMs and their derivatives in Moroccan shellfish. PY 2017 PD FEB SO International Journal of Science and Research (IJSR) SN 2319-7064 VL 6 IS 2 DI 10.21275/24121602 ID 48342 ER EF