FN Archimer Export Format
PT J
TI Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages
BT 
AF AZEMA, Patrick
   LAMY, Jean-Baptiste
   BOUDRY, Pierre
   RENAULT, Tristan
   TRAVERS, Marie-Agnes
   DEGREMONT, Lionel
AS 1:1;2:1;3:2;4:3;5:1;6:1;
FF 1:;2:PDG-RBE-SG2M-LGPMM;3:PDG-RBE-PFOM;4:PDG-RBE;5:PDG-RBE-SG2M-LGPMM;6:PDG-RBE-SG2M-LGPMM;
C1 IFREMER, Lab Genet & Pathol Mollusques Marins, Ave Mus de Loup, F-17390 La Tremblade, France.
   IFREMER, Ctr Bretagne, Lab Sci Environm Marin, UBO,CNRS,IRD,UMR LEMAR 6539, CS 10070, F-29280 Plouzane, France.
   IFREMER, Dept Ressources Biol & Environm, Rue Ile dYeu, F-44300 Nantes, France.
C2 IFREMER, FRANCE
   IFREMER, FRANCE
   IFREMER, FRANCE
SI LA TREMBLADE
   BREST
   NANTES
SE PDG-RBE-SG2M-LGPMM
   PDG-RBE-PFOM
   PDG-RBE
UM LEMAR
IN WOS Ifremer jusqu'en 2018
   DOAJ
IF 3.743
TC 74
UR https://archimer.ifremer.fr/doc/00372/48350/48518.pdf
   https://archimer.ifremer.fr/doc/00372/48350/48519.pdf
   https://archimer.ifremer.fr/doc/00372/48350/48521.pdf
   https://archimer.ifremer.fr/doc/00372/48350/48522.pdf
LA English
DT Article
AB Background  In France, two main diseases threaten Pacific oyster production. Since 2008, Crassostrea gigas spat have suffered massive losses due to the ostreid herpesvirus OsHV-1, and since 2012, significant mortalities in commercial-size adults have been related to infection by the bacterium Vibrio aestuarianus. The genetic basis for resistance to V. aestuarianus and OsHV-1 and the nature of the genetic correlation between these two traits were investigated by using 20 half-sib sire families, each containing two full-sib families. For each disease, controlled infectious challenges were conducted using naïve oysters that were 3 to 26 months old. In addition, siblings were tested under field, pond and raceway conditions to determine whether laboratory trials reflected mortality events that occur in the oyster industry. Results  First, we estimated the genetic basis of resistance to V. aestuarianus in C. gigas. Susceptibility to the infection was low for oysters in spat stage but increased with later life stages. Second, we confirmed a strong genetic basis of resistance to OsHV-1 infection at early stages and demonstrated that it was also strong at later stages. Most families had increased resistance to OsHV-1 infection from the spat to adult stages, while others consistently showed low or high mortality rates related to OsHV-1 infection, regardless of the life stage. Our third main finding was the absence of genetic correlations between resistance to OsHV-1 infection and resistance to V. aestuarianus infection. Conclusions  Selective breeding to enhance resistance to OsHV-1 infection could be achieved through selective breeding at early stages and would not affect resistance to V. aestuarianus infection. However, our results suggest that the potential to select for improved resistance to V. aestuarianus is lower. Selection for dual resistance to OsHV-1 and V. aestuarianus infection in C. gigas might reduce the impact of these two major diseases by selecting families that have the highest breeding values for resistance to both diseases.
PY 2017
PD FEB
SO Genetics Selection Evolution
SN 0999-193X
PU Biomed Central Ltd
VL 49
IS 23
UT 000394716200001
BP 1
EP 16
DI 10.1186/s12711-017-0297-2
ID 48350
ER

EF