FN Archimer Export Format PT J TI Remodeling of the cycling transcriptome of the oyster Crassostrea gigas by the harmful algae Alexandrium minutum BT AF PAYTON, Laura PERRIGAULT, Mickael HOEDE, Claire MASSABUAU, Jean-Charles SOW, Mohamedou HUVET, Arnaud BOULLOT, Floriane FABIOUX, Caroline HEGARET, Helene TRAN, Damien AS 1:1,2;2:1,2;3:3;4:1,2;5:1;6:4;7:4,5;8:4,5;9:4,5;10:1,2; FF 1:;2:;3:;4:;5:;6:PDG-RBE-PFOM-PI;7:;8:;9:;10:; C1 Univ Bordeaux, EPOC, UMR 5805, F-33120 Arcachon, France. CNRS, EPOC, UMR 5805, F-33120 Arcachon, France. Univ Toulouse, Plate Forme Bioinformat Genotoul, MIAT, INRA, F-31326 Castanet Tolosan, France. IFREMER, Lab Sci Environm Marin LEMAR, UMR UBO CNRS IRD IFREMER 6539, CS 10070, F-29280 Plouzane, France. Univ Bretagne Occidentale, Lab Sci Environm Marin LEMAR, Inst Univ Europeen Mer, UMR CNRS UBO IRD IFREMER 6539, F-29280 Plouzane, France. C2 UNIV BORDEAUX, FRANCE CNRS, FRANCE UNIV TOULOUSE, FRANCE IFREMER, FRANCE UBO, FRANCE SI BREST SE PDG-RBE-PFOM-PI UM LEMAR IN WOS Ifremer jusqu'en 2018 DOAJ copubli-france copubli-univ-france IF 4.122 TC 20 UR https://archimer.ifremer.fr/doc/00389/50008/50595.pdf https://archimer.ifremer.fr/doc/00389/50008/50596.pdf https://archimer.ifremer.fr/doc/00389/50008/50597.xls LA English DT Article AB As a marine organism, the oyster Crassostrea gigas inhabits a complex biotope governed by interactions between the moon and the sun cycles. We used next-generation sequencing to investigate temporal regulation of oysters under light/dark entrainment and the impact of harmful algal exposure. We found that ≈6% of the gills’ transcriptome exhibits circadian expression, characterized by a nocturnal and bimodal pattern. Surprisingly, a higher number of ultradian transcripts were also detected under solely circadian entrainment. The results showed that a bloom of Alexandrium minutum generated a remodeling of the bivalve’s temporal structure, characterized by a loss of oscillations, a genesis of de novo oscillating transcripts, and a switch in the period of oscillations. These findings provide unprecedented insights into the diurnal landscape of the oyster’s transcriptome and pleiotropic remodeling due to toxic algae exposure, revealing the intrinsic plasticity of the cycling transcriptome in oysters. PY 2017 PD JUL SO Scientific Reports SN 2045-2322 PU Nature Publishing Group VL 7 IS 1 UT 000403318400034 DI 10.1038/s41598-017-03797-4 ID 50008 ER EF