Bioprospecting for Exopolysaccharides from Deep-Sea Hydrothermal Vent Bacteria: Relationship between Bacterial Diversity and Chemical Diversity

Type Article
Date 2017-09
Language English
Author(s) Delbarre-Ladrat ChristineORCID1, Salas Marcia Leyva2, Sinquin CorinneORCID1, Zykwinska AgataORCID1, Colliec-Jouault SylviaORCID1
Affiliation(s) 1 : IFREMER, Lab Ecosyst Microbiens & Mol Marines Biotechnol, Rue Ile dYeu,BP 21105, F-44311 Nantes, France.
2 : Givaudan France SAS, F-51110 Pomacle, France.
Source Microorganisms (2076-2607) (Mdpi), 2017-09 , Vol. 5 , N. 3 , P. 63 (13p.)
DOI 10.3390/microorganisms5030063
WOS© Times Cited 6
Note This article belongs to the Special Issue Marine-Derived Exopolysaccharides to Mimic Glycosaminoglycans
Keyword(s) exopolysaccharides, GAG, marine bacteria, glycopolymers, sulfate, production
Abstract

Many bacteria biosynthesize structurally diverse exopolysaccharides (EPS) and excrete them into their surrounding environment. The EPS functional features have found many applications in industries such as cosmetics and pharmaceutics. In particular, some EPS produced by marine bacteria are composed of uronic acids, neutral sugars, and N-acetylhexosamines, and may also bear some functional sulfate groups. This suggests that they can share common structural features with glycosaminoglycans (GAG) like the two EPS (HE800 and GY785) originating from the deep sea. In an attempt to discover new EPS that may be promising candidates as GAG-mimetics, fifty-one marine bacterial strains originating from deep-sea hydrothermal vents were screened. The analysis of the EPS chemical structure in relation to bacterial species showed that Vibrio, Alteromonas, and Pseudoalteromonas strains were the main producers. Moreover, they produced EPS with distinct structural features, which might be useful for targeting marine bacteria that could possibly produce structurally GAG-mimetic EPS.

Full Text
File Pages Size Access
Publisher's official version 13 1 MB Open access
File S4 60 KB Open access
Table S1 12 KB Open access
Table S2 15 KB Open access
Table S3 10 KB Open access
Top of the page

How to cite 

Delbarre-Ladrat Christine, Salas Marcia Leyva, Sinquin Corinne, Zykwinska Agata, Colliec-Jouault Sylvia (2017). Bioprospecting for Exopolysaccharides from Deep-Sea Hydrothermal Vent Bacteria: Relationship between Bacterial Diversity and Chemical Diversity. Microorganisms, 5(3), 63 (13p.). Publisher's official version : https://doi.org/10.3390/microorganisms5030063 , Open Access version : https://archimer.ifremer.fr/doc/00399/51090/