FN Archimer Export Format
PT J
TI Metabolic response to hypoxia in European sea bass (Dicentrarchus labrax) displays developmental plasticity
BT 
AF CADIZ, Laura
   ZAMBONINO-INFANTE, Jose-Luis
   QUAZUGUEL, Patrick
   MADEC, Lauriane
   LE DELLIOU, Herve
   MAZURAIS, David
AS 1:1;2:1;3:1;4:1;5:1;6:1;
FF 1:PDG-RBE-PFOM-ARN;2:PDG-RBE-PFOM-ARN;3:PDG-RBE-PFOM-ARN;4:PDG-RBE-PFOM-ARN;5:PDG-RBE-PFOM-ARN;6:PDG-RBE-PFOM-ARN;
C1 IFREMER, Ctr Bretagne, LEMAR UMR 6539, F-29280 Plouzane, France.
C2 IFREMER, FRANCE
SI BREST
SE PDG-RBE-PFOM-ARN
UM LEMAR
IN WOS Ifremer jusqu'en 2018
IF 1.99
TC 27
UR https://archimer.ifremer.fr/doc/00404/51536/52126.pdf
LA English
DT Article
DE ;Hypoxia;Developmental plasticity;Metabolism;European sea bass
AB Several physiological functions in fish are shaped by environmental stimuli received during early life. In particular, early-life hypoxia has been reported to have long-lasting effects on fish metabolism, with potential consequences for fish life history traits. In the present study, we examine whether the synergistic stressors hypoxia (40% and 100% air saturation) and temperature (15° and 20 °C), encountered during early life, could condition later metabolic response in European sea bass (Dicentrarchus labrax) juveniles. Growth rate and metabolic parameters related to carbohydrate and lipid metabolism in the liver were investigated at the juvenile stage under normoxic and chronic hypoxic conditions. Juvenile growth rates were significantly lower (p < 1 × 10− 6) under hypoxic conditions and were not improved by prior early-life exposure to hypoxia. Growth was 1.3 times higher (p < 5 × 10− 3) in juveniles reared at 15 °C during the larval stage than those reared at 20 °C, suggesting that compensatory growth had occurred. Early-life exposure to hypoxia induced higher (p < 2 × 10− 6) glycogen stores in juveniles even though there was no apparent regulation of their carbohydrate metabolism. In the liver of juveniles exposed to chronic hypoxia, lower glycogen content combined with stimulation of phosphoenolpyruvate carboxykinase gene expression and higher lactate concentration indicated a stimulation of the anaerobic glycolytic pathway. Furthermore, hypoxia only induced lower (p < 1 × 10− 3) lipid content in the liver of juveniles that had experienced 15 °C at the larval stage. The present study provides evidence that environmental conditions experienced during early life shape the metabolic traits of D. labrax with potential consequences for juvenile physiological performance. 
PY 2018
PD JAN
SO Comparative Biochemistry And Physiology B-biochemistry & Molecular Biology
SN 1096-4959
PU Elsevier Science Inc
VL 215
UT 000417657800001
BP 1
EP 9
DI 10.1016/j.cbpb.2017.09.005
ID 51536
ER

EF