FN Archimer Export Format
PT J
TI Variation in the link between oxygen consumption and ATP production, and its relevance for animal performance
BT 
AF SALIN, Karine
   AUER, Sonya K.
   REY, Benjamin
   SELMAN, Colin
   METCALFE, Neil B.
AS 1:1;2:1;3:2,3;4:1;5:1;
FF 1:;2:;3:;4:;5:;
C1 Univ Glasgow, Coll Med Vet & Life Sci, Inst Biodivers Anim Hlth & Comparat Med, Glasgow, Lanark, Scotland.
   Univ Lyon 1, CNRS, UMR 5558, Lab Biometrie & Biol Evolut, F-69365 Lyon, France.
   Univ Witwatersrand, Fac Hlth Sci, Sch Physiol, Brain Funct Res Grp, Johannesburg, South Africa.
C2 UNIV GLASGOW, UK
   UNIV LYON, FRANCE
   UNIV WITWATERSRAND, SOUTH AFRICA
IF 4.823
TC 173
UR https://archimer.ifremer.fr/doc/00414/52509/53322.pdf
LA English
DT Article
DE ;mitochondrial coupling efficiency;life history;oxidative stress;reactive oxygen species;trade-off;uncoupling
AB It is often assumed that an animal's metabolic rate can be estimated through measuring the whole-organism oxygen consumption rate. However, oxygen consumption alone is unlikely to be a sufficient marker of energy metabolism in many situations. This is due to the inherent variability in the link between oxidation and phosphorylation; that is, the amount of adenosine triphosphate (ATP) generated per molecule of oxygen consumed by mitochondria (P/O ratio). In this article, we describe how the P/O ratio can vary within and among individuals, and in response to a number of environmental parameters, including diet and temperature. As the P/O ratio affects the efficiency of cellular energy production, its variability may have significant consequences for animal performance, such as growth rate and reproductive output. We explore the adaptive significance of such variability and hypothesize that while a reduction in the P/O ratio is energetically costly, it may be associated with advantages in terms of somatic maintenance through reduced production of reactive oxygen species. Finally, we discuss how considering variation in mitochondrial efficiency, together with whole-organism oxygen consumption, can permit a better understanding of the relationship between energy metabolism and life history for studies in evolutionary ecology.
PY 2015
PD AUG
SO Proceedings Of The Royal Society B-biological Sciences
SN 0962-8452
PU Royal Soc
VL 282
IS 1812
UT 000362305500002
BP 14
EP 22
DI 10.1098/rspb.2015.1028
ID 52509
ER

EF