FN Archimer Export Format
PT J
TI Tectus niloticus (Tegulidae, Gastropod) as a Novel Vector of Ciguatera Poisoning: Detection of Pacific Ciguatoxins in Toxic Samples from Nuku Hiva Island (French Polynesia)
BT 
AF DARIUS, Helene Taiana
   ROUE, Melanie
   SIBAT, Manoella
   VIALLON, Jerome
   GATTI, Clemence Mahana Iti
   VANDERSEA, Mark W.
   TESTER, Patricia A.
   LITAKER, R. Wayne
   AMZIL, Zouher
   HESS, Philipp
   CHINAIN, Mireille
AS 1:1;2:2;3:3;4:1;5:1;6:4;7:5;8:4;9:3;10:3;11:1;
FF 1:;2:;3:PDG-ODE-DYNECO-PHYC;4:;5:;6:;7:;8:;9:PDG-ODE-DYNECO-PHYC;10:PDG-ODE-DYNECO-PHYC;11:;
C1 ILM, Lab Tox Microalgae, EIO, UMR 241, POB 30, F-98713 Tahiti, French Polynesi, France.
   IRD, UMR 241, EIO, POB 529, F-98713 Tahiti, French Polynesi, France.
   IFREMER, Phycotoxins Lab, F-44311 Nantes, France.
   NOAA, Natl Ocean Serv, Ctr Coastal Ocean Sci, Beaufort Lab, Beaufort, NC 28516 USA.
   Ocean Tester LLC, Beaufort, NC 28516 USA.
C2 INST LOUIS MALARDE, FRANCE
   IRD, FRANCE
   IFREMER, FRANCE
   NOAA, USA
   OCEAN TESTER LLC, USA
SI NANTES
SE PDG-ODE-DYNECO-PHYC
UM EIO
IN WOS Ifremer jusqu'en 2018
   DOAJ
   copubli-france
   copubli-p187
   copubli-int-hors-europe
IF 3.895
TC 48
UR https://archimer.ifremer.fr/doc/00426/53798/54719.pdf
LA English
DT Article
DE ;ciguatera poisoning;ciguatoxins;Tectus niloticus;gastropods;Gambierdiscus polynesiensis;qPCR assays;CBA-N2a;LC-MS;MS
AB Ciguatera fish poisoning (CFP) is a foodborne disease caused by the consumption of seafood (fish and marine invertebrates) contaminated with ciguatoxins (CTXs) produced by dinoflagellates in the genus Gambierdiscus. The report of a CFP-like mass-poisoning outbreak following the consumption of Tectus niloticus (Tegulidae, Gastropod) from Anaho Bay on Nuku Hiva Island (Marquesas archipelago, French Polynesia) prompted field investigations to assess the presence of CTXs in T. niloticus. Samples were collected from Anaho Bay, 1, 6 and 28 months after this poisoning outbreak, as well as in Taiohae and Taipivai bays. Toxicity analysis using the neuroblastoma cell-based assay (CBA-N2a) detected the presence of CTXs only in Anaho Bay T. niloticus samples. This is consistent with qPCR results on window screen samples indicating the presence of Gambierdiscus communities dominated by the species G. polynesiensis in Anaho Bay. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analyses revealed that P-CTX-3B was the major congener, followed by P-CTX-3C, P-CTX-4A and P-CTX-4B in toxic samples. Between July 2014 and November 2016, toxin content in T. niloticus progressively decreased, but was consistently above the safety limit recommended for human consumption. This study confirms for the first time T. niloticus as a novel vector of CFP in French Polynesia. 
PY 2018
PD JAN
SO Toxins
SN 2072-6651
PU Mdpi Ag
VL 10
IS 1
UT 000424096500002
DI 10.3390/toxins10010002
ID 53798
ER

EF