FN Archimer Export Format
PT J
TI Infectivity and RNA Persistence of a Norovirus Surrogate, the Tulane Virus, in Oysters
BT 
AF POLO, David
   SCHAEFFER, Julien
   TEUNIS, Peter
   BUCHET, Vincent
   LE GUYADER, Soizick
AS 1:1;2:1;3:2;4:3;5:1;
FF 1:;2:PDG-RBE-SGMM-LSEM;3:;4:PDG-RBE-SGMM-LSPC;5:PDG-RBE-SGMM-LSEM;
C1 Inst Francais Rech Exploitat Mer IFREMER, Lab Microbiol, Lab Sante Environm & Microbiol Sante, Genet & Microbiol Mollusques, Nantes, France.
   Emory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA.
   Inst Francais Rech Exploitat Mer IFREMER, Lab Securisat Prod Conchyliculture Sante, Genet & Microbiol Mollusques, Bouin, France.
C2 IFREMER, FRANCE
   UNIV EMORY, USA
   IFREMER, FRANCE
SI NANTES
   BOUIN
SE PDG-RBE-SGMM-LSEM
   PDG-RBE-SGMM-LSPC
IN WOS Ifremer jusqu'en 2018
   DOAJ
   copubli-int-hors-europe
IF 4.259
TC 24
UR https://archimer.ifremer.fr/doc/00436/54736/56182.pdf
   https://archimer.ifremer.fr/doc/00436/54736/56184.pdf
LA English
DT Article
DE ;infectious virus;genome detection;oysters;persistence;shellfish outbreaks
AB Oysters, being filter feeders, can accumulate some human pathogens such as norovirus, a highly infectious calicivirus, most common cause of acute gastroenteritis worldwide. Accumulated virus decays over a period of days to weeks, possibly rendering contaminated oysters safe again. Sensitive molecular methods have been set up for shellfish analysis but without answering the question of infectious virus detection. Using the Tulane virus (TV), a norovirus surrogate that recognizes the same ligand as human norovirus in oyster tissues, the genome and infectious virus decay rates were estimated using inverse linear regression in a Bayesian framework for genome copies. Infectivity decreased faster than genome copies but infectious viruses were detected for several days. Quantifying the decrease in viral infectivity and genome detection in oysters over such a long period may help local authorities to manage production areas implicated in shellfish-borne outbreaks, and thus protect consumers. 
PY 2018
PD APR
SO Frontiers In Microbiology
SN 1664-302X
PU Frontiers Media Sa
VL 9
IS 716
UT 000429800500001
DI 10.3389/fmicb.2018.00716
ID 54736
ER

EF