FN Archimer Export Format
PT J
TI Significance of metallothioneins in differential cadmium accumulation kinetics between two marine fish species
BT 
AF LE CROIZIER, Gael
   LACROIX, Camille
   ARTIGAUD, Sebastien
   LE FLOCH, Stephane
   RAFFRAY, Jean
   PENICAUD, Virginie
   COQUILLE, Valerie
   AUTIER, Julien
   ROUGET, Marie-Laure
   LE BAYON, Nicolas
   LAE, Raymond
   DE MORAIS, Luis Tito
AS 1:1;2:2;3:1;4:2;5:1;6:1;7:1;8:1;9:3;10:4;11:1;12:1;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:PDG-RBE-PFOM-LARN;11:;12:;
C1 UBO, CNRS, UMR 6539, Lab Sci Environm Marin LEMAR,IRD,IFREMER, BP 70, F-29280 Plouzane, France.
   Ctr Documentat Res & Expt Accidental Water Pollut, 715 Rue Alain Colas,CS 41836, F-29218 Brest 2, France.
   UBO, CNRS, UMS 3113, IUEM, F-29280 Plouzane, France.
   IFREMER, Unite Physiol Fonct Organismes Marins, LEMAR UMR 6539, Ctr Brest,Lab PFOM ARN, BP 70, F-29280 Plouzane, France.
C2 UBO, FRANCE
   CEDRE, FRANCE
   UBO, FRANCE
   IFREMER, FRANCE
SI BREST
SE PDG-RBE-PFOM-LARN
UM LEMAR
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 5.714
TC 46
UR https://archimer.ifremer.fr/doc/00437/54810/56480.pdf
LA English
DT Article
DE ;Metal;Trace element;Dicentrarchus labrax;Solea senegalensis;Chronic dietary exposure
AB Impacted marine environments lead to metal accumulation in edible marine fish, ultimately impairing human health. Nevertheless, metal accumulation is highly variable among marine fish species. In addition to ecological features, differences in bioaccumulation can be attributed to species-related physiological processes, which were investigated in two marine fish present in the Canary Current Large Marine Ecosystem (CCLME), where natural and anthropogenic metal exposure occurs. The European sea bass Dicentrarchus labrax and Senegalese sole Solea senegalensis were exposed for two months to two environmentally realistic dietary cadmium (Cd) doses before a depuration period. Organotropism (i.e., Cd repartition between organs) was studied in two storage compartments (the liver and muscle) and in an excretion vector (bile). To better understand the importance of physiological factors, the significance of hepatic metallothionein (MT) concentrations in accumulation and elimination kinetics in the two species was explored. Accumulation was faster in the sea bass muscle and liver, as inferred by earlier Cd increase and a higher accumulation rate. The elimination efficiency was also higher in the sea bass liver compared to sole, as highlighted by greater biliary excretion. In the liver, no induction of MT synthesis was attributed to metal exposure, challenging the relevance of using MT concentration as a biomarker of metal contamination. However, the basal MT pools were always greater in the liver of sea bass than in sole. This species-specific characteristic might have enhanced Cd biliary elimination and relocation to other organs such as muscle through the formation of more Cd/MT complexes. Thus, MT basal concentrations seem to play a key role in the variability observed in terms of metal concentrations in marine fish species. 
PY 2018
PD MAY
SO Environmental Pollution
SN 0269-7491
PU Elsevier Sci Ltd
VL 236
UT 000429187500049
BP 462
EP 476
DI 10.1016/j.envpol.2018.01.002
ID 54810
ER

EF