FN Archimer Export Format
PT J
TI Ecologically realistic model of infection for exploring the host damage caused by Vibrio aestuarianus
BT 
AF PARIZADEH, Leila
   TOURBIEZ, Delphine
   GARCIA, Celine
   HAFFNER, Philippe
   DEGREMONT, Lionel
   LE ROUX, Frederique
   TRAVERS, Marie-Agnes
AS 1:1;2:1;3:1;4:1,2;5:1;6:3,4;7:1;
FF 1:PDG-RBE-SG2M-LGPMM;2:PDG-RBE-SGMM-LGPMM;3:PDG-RBE-SGMM-LGPMM;4:PDG-RBE-IHPE;5:PDG-RBE-SGMM-LGPMM;6:PDG-RBE-PFOM;7:PDG-RBE-SGMM-LGPMM;
C1 IFREMER, SG2M LGPMM, Lab Genet & Pathol Mollusques Marins, Ave Mus Loup, F-17390 La Tremblade, France.
   UM, IFREMER, CNRS, IHPE,UPVD,UMR 5244, Pl Eugene Bataillon CC80, F-34095 Montpellier 05, France.
   IFREMER, Unite Physiol Fonct Organismes Marins, CS 10070, F-29280 Plouzane, France.
   UPMC Paris 06, Sorbonne Univ, Stn Biol Roscoff, Integrat Biol Marine Models,CNRS,UMR 8227, CS 90074, F-29688 Roscoff, France.
C2 IFREMER, FRANCE
   UNIV MONTPELLIER, FRANCE
   IFREMER, FRANCE
   UNIV PARIS 06, FRANCE
SI LA TREMBLADE
   MONTPELLIER
   ROSCOFF
SE PDG-RBE-SG2M-LGPMM
   PDG-RBE-SGMM-LGPMM
   PDG-RBE-IHPE
   PDG-RBE-PFOM
UM IHPE
IN WOS Ifremer jusqu'en 2018
   copubli-france
   copubli-univ-france
IF 5.147
TC 17
UR https://archimer.ifremer.fr/doc/00446/55761/57423.pdf
LA English
DT Article
AB Although vibrios are frequently associated with marine organisms mortality outbreaks, knowledge on their ecology and pathogenicity is sparse, thus limiting disease management and prophylactic strategies. Here, we investigated V. aestuarianus infection onset and progression in the wild, taking advantage of a “claire” pond: a semi‐closed system with limited seawater renewal, theoretically more adapted to disease transmission. We showed a positive association of the bacteria with oysters, which can constitute a reservoir for the bacteria in the winter. Moreover, passage through oysters was found to be necessary for experimental disease reproduction as vibrios shedding from diseased oysters has higher infectivity than from in vitro grown. We next developed an experimental “ecologically realistic” infection model in a mesocosm, allowing infection by natural route. By means of this non‐invasive protocol, we analysed the pathogenesis of the bacteria and demonstrated the importance of haemolymph for initial colonisation and the septicaemic nature of this disease. 
PY 2018
PD DEC
SO Environmental Microbiology
SN 1462-2912
PU Wiley
VL 20
IS 12
UT 000453004500012
BP 4343
EP 4355
DI 10.1111/1462-2920.14350
ID 55761
ER

EF