FN Archimer Export Format PT J TI The mitochondrial contribution to animal performance, adaptation, and life-history variation BT AF HOOD, Wendy R. AUSTAD, Steven N. BIZE, Pierre JIMENEZ, Ana Gabriela MONTOOTH, Kristi L. SCHULTE, Patricia M. SCOTT, Graham R. SOKOLOVA, Inna TREBERG, Jason R. SALIN, Karine AS 1:1;2:2;3:3;4:4;5:5;6:6;7:7;8:8,9;9:10,11,12;10:13; FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:PDG-RBE-PFOM-LARN; C1 Auburn Univ, Dept Biol Sci, Auburn, AL 36849 USA. Univ Alabama Birmingham, Dept Biol, Birmingham, AL 35294 USA. Univ Aberdeen, Sch Biol Sci, Aberdeen AB24 2TZ, Scotland. Colgate Univ, Dept Biol, 13 Oak Dr, Hamilton, NY 13346 USA. Univ Nebraska, Sch Biol Sci, Lincoln, NE 68588 USA. Univ British Columbia, Dept Zool, Vancouver, BC V6T 1Z4, Canada. McMaster Univ, Dept Biol, Hamilton, ON L8S 4K1, Canada. Univ Rostock, Inst Biol Sci, Dept Marine Biol, D-18055 Rostock, Germany. Univ Rostock, Interdisciplinary Fac, Dept Maritime Syst, D-18055 Rostock, Germany. Univ Manitoba, Dept Biol Sci, Winnipeg, MB R3T 2N2, Canada. Univ Manitoba, Dept Food & Human Nutr Sci, Winnipeg, MB R3T 2N2, Canada. Univ Manitoba, Ctr Aging, Winnipeg, MB R3T 2N2, Canada. IFREMER, Unite Physiol Fonct Organismes Marins LEMAR UMR 6, F-29280 Plouzane, France. C2 UNIV AUBURN, USA UNIV ALABAMA BIRMINGHAM, USA UNIV ABERDEEN, UK UNIV COLGATE, USA UNIV NEBRASKA, USA UNIV BRITISH COLUMBIA, CANADA UNIV MCMASTER, CANADA UNIV ROSTOCK, GERMANY UNIV ROSTOCK, GERMANY UNIV MANITOBA, CANADA UNIV MANITOBA, CANADA UNIV MANITOBA, CANADA IFREMER, FRANCE SI BREST SE PDG-RBE-PFOM-LARN UM LEMAR IN WOS Ifremer jusqu'en 2018 copubli-europe copubli-int-hors-europe IF 3.101 TC 27 UR https://archimer.ifremer.fr/doc/00449/56023/57543.pdf LA English DT Article AB Animals display tremendous variation in their rates of growth, reproductive output, and longevity. While the physiological and molecular mechanisms that underlie this variation remain poorly understood, the performance of the mitochondrion has emerged as a key player. Mitochondria not only impact the performance of eukaryotes via their capacity to produce ATP, but they also play a role in producing heat and reactive oxygen species and function as a major signalling hub for the cell. The papers included in this special issue emerged from a symposium titled “Inside the Black Box: The Mitochondrial Basis of Life-history Variation and Animal Performance”. Based on studies of diverse animal taxa, three distinct themes emerged from these papers. 1) When linking mitochondrial function to components of fitness, it is crucial that mitochondrial assays are performed in conditions as close as the intracellular conditions experienced by the mitochondria in vivo. 2) Functional plasticity allows mitochondria to retain their performance, as well as that of their host, over a range of exogenous conditions, and selection on mitochondrial and nuclear-derived proteins can optimize the match between the environment and the bioenergetic capacity of the mitochondrion. Finally, 3) studies of wild and wild-derived animals suggest that mitochondria play a central role in animal performance and life history strategy. Taken as a whole, we hope that these papers will foster discussion and inspire new hypotheses and innovations that will further our understanding of the mitochondrial processes that underlie variation in life history traits and animal performance. PY 2018 PD SEP SO Integrative And Comparative Biology SN 1540-7063 PU Oxford Univ Press Inc VL 58 IS 3 UT 000451996200011 BP 480 EP 485 DI 10.1093/icb/icy089 ID 56023 ER EF