FN Archimer Export Format
PT J
TI Exploring the chemodiversity of tropical microalgae for the discovery of natural antifouling compounds
BT 
AF Réveillon, Damien
   Tunin-Ley, Alina
   Grondin, Isabelle
   Othmani, Ahlem
   Zubia, Mayalen
   Bunet, Robert
   Turquet, Jean
   Culioli, Gérald
   Briand, Jean-François
AS 1:1,2;2:3;3:4;4:1;5:5;6:6;7:3;8:1;9:1;
FF 1:PDG-ODE-DYNECO-PHYC;2:;3:;4:;5:;6:;7:;8:;9:;
C1 MAPIEM EA 4323, Université de Toulon, Toulon, France
   Laboratoire Phycotoxines, Ifremer, Nantes, France
   Hydrô Réunion, CBEM c/o CYROI, Sainte Clotilde, La Réunion, France
   Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments (LCSNSA), Université de La Réunion, Saint-Denis, France
   Université de Polynésie Française, UMR-EIO, LabEx-CORAIL, BP 6570, 98702 Faa’a, Tahiti, French Polynesia
   Institut Océanographique Paul Ricard, Ile des Embiez, Six-Fours-les-Plages, France
C2 UNIV TOULON, FRANCE
   IFREMER, FRANCE
   HYDRO REUNION, FRANCE
   UNIV LA REUNION, FRANCE
   UNIV POLYNESIE FRANCAISE, FRANCE
   INST OCEANOG PAUL RICARD, FRANCE
SI NANTES
SE PDG-ODE-DYNECO-PHYC
UM EIO
IN WOS Ifremer UPR
   WOS Cotutelle UMR
   copubli-france
   copubli-univ-france
IF 3.016
TC 10
UR https://archimer.ifremer.fr/doc/00454/56608/58333.pdf
LA English
DT Article
DE ;Microalgae;Antifouling;Bioassay;Chemodiversity;Bioprospecting;Metabolomics
AB Marine microalgae and cyanobacteria have largely been studied for their biotechnological potential and proved their ability to produce a wide array of bioactive molecules. We investigated the antifouling potential of unexplored benthic tropical microalgae using anti-adhesion and toxicity bioassays against two major micro- and ma crobiofoulers, namely bacteria and barnacles. Fifty strains belonging to six phyla [Cyanobacteria, Miozoa (Dinoflagellata), Bacillariophyta, Cryptophyta, Rhodophyta and Haptophyta] were isolated from southwestern Islands of the Indian Ocean. They were chosen in order to represent as much as possible the huge biodiversity of such a rich tropical ecosystem. The associated chemodiversity was highlighted by both NMR- and LC-MS-based metabolomics. The screening of 84 algal fractions revealed that the anti-adhesion activity was concentrated in methanolic ones (i.e. 93% of all active fractions). Our results confirmed that microalgae constitute a promising source of natural antimicrofoulants as 17 out of the 30 active fractions showed high or very high capacity to inhibit the adhesion of three biofilm-forming marine bacteria. Dinoflagellate-derived fractions were the most active, both in terms of number and intensity. However, dinoflagellates were also more toxic and may not be suitable as a source of environmentally friendly antifouling compounds, in contrast to diatoms, e.g. Navicula mollis. The latter and two dinoflagellates of the genus Amphidinium also had interesting anti-settlement activities while being moderately toxic to barnacle larvae. Our approach, combining the bioprospecting of a large number of tropical microalgae for their anti-settlement potential and metabolomics analyses, constituted a first step towards the discovery of alternative ecofriendly antifoulants. 
PY 2019
PD FEB
SO Journal Of Applied Phycology
SN 0921-8971
PU Springer Nature America, Inc
VL 31
IS 1
UT 000458698200029
BP 319
EP 333
DI 10.1007/s10811-018-1594-z
ID 56608
ER

EF