FN Archimer Export Format
PT J
TI Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1)
BT 
AF LAFONT, Maxime
   GONCALVES, Priscila
   GUO, Ximing
   MONTAGNANI, Caroline
   RAFTOS, David
   GREEN, Timothy
AS 1:1,2,5;2:1,3;3:4;4:2;5:1,3;6:1,3;
FF 1:;2:;3:;4:PDG-RBE-IHPE;5:;6:;
C1 Sydney Inst Marine Sci, Sydney, NSW, Australia.
   Univ Perpignan, IFREMER, CNRS, IHPE,Univ Montpellier, Via Domitia, Perpignan, France.
   Macquarie Univ, Dept Biol Sci, Sydney, NSW, Australia.
   Rutgers State Univ, Haskin Shellfish Res Lab, Port Norris, NJ USA.
   Univ Perpignan, IFREMER, CNRS, IHPE,Univ Montpellier, Via Domitia, Perpignan, France.
C2 SYDNEY INST MARINE SCI, AUSTRALIA
   IFREMER, FRANCE
   UNIV MACQUARIE, AUSTRALIA
   UNIV RUTGERS STATE, USA
   UNIV PERPIGNAN, FRANCE
SI MONTPELLIER
SE PDG-RBE-IHPE
UM IHPE
IN WOS Ifremer UMR
   WOS Cotutelle UMR
   copubli-france
   copubli-univ-france
   copubli-int-hors-europe
IF 3.192
TC 26
UR https://archimer.ifremer.fr/doc/00459/57033/58930.pdf
LA English
DT Article
DE ;Crassostrea gigas;OsHV-1;Transgenerational immune priming;Trained immunity;RNA-seq
AB The oyster's immune system is capable of adapting upon exposure to a pathogen-associated molecular pattern (PAMP) to have an enhanced secondary response against the same type of pathogen. This has been demonstrated using poly(I:C) to elicit an antiviral response in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus (OsHV-1). Improved survival following exposure to poly(I:C) has been found in later life stages (within-generational immune priming) and in the next generation (transgenerational immune priming). The mechanism that the oyster uses to transfer immunity to the next generation is unknown. Here we show that oyster larvae have higher survival to OsHV-1 when their mothers, but not their fathers, are exposed to poly(I:C) prior to spawning. RNA-seq provided no evidence to suggest that parental exposure to poly(I:C) reconfigures antiviral gene expression in unchallenged larvae. We conclude that the improved survival of larvae might occur via maternal provisioning of antiviral compounds in the eggs. 
PY 2019
PD FEB
SO Developmental And Comparative Immunology
SN 0145-305X
PU Elsevier Sci Ltd
VL 91
UT 000451492900003
BP 17
EP 25
DI 10.1016/j.dci.2018.09.022
ID 57033
ER

EF