FN Archimer Export Format
PT J
TI Population-specific variations of the genetic architecture of sex determination in wild European sea bass Dicentrarchus labrax L.
BT 
AF Faggion, Sara
   Vandeputte, Marc
   Chatain, Beatrice
   Gagnaire, Pierre-Alexandre
   Allal, Francois
AS 1:1,2;2:2,3;3:2;4:4;5:2;
FF 1:;2:;3:PDG-RBE-MARBEC-LAAAS;4:;5:PDG-RBE-MARBEC-LAAAS;
C1 Department of Comparative Biomedicine and Food Science, University of Padua, Agripolis, Viale dell’Università, 16, 35020 Legnaro, PD, Italy
   MARBEC, Univ. Montpellier, Ifremer, CNRS, IRD, Palavas-les- Flots, France
   GABI, INRA, AgroParisTech, Université Paris-Saclay, Jouy-en- Josas, 78350 Paris, France
   ISEM, Univ. Montpellier, CNRS, IRD, EPHE, Montpellier, France
C2 UNIV PADUA, ITALY
   IFREMER, FRANCE
   INRA, FRANCE
   CNRS, FRANCE
SI PALAVAS
SE PDG-RBE-MARBEC-LAAAS
UM MARBEC
IN WOS Ifremer UMR
   copubli-france
   copubli-p187
   copubli-europe
   copubli-univ-france
IF 3.436
TC 18
UR https://archimer.ifremer.fr/doc/00464/57609/59864.pdf
LA English
DT Article
AB Polygenic sex determination (PSD) may show variations in terms of genetic and environmental components between populations of fish species exposed/adapted to different environments. The European sea bass (Dicentrarchus labrax) is an interesting model, combining both a PSD system and a genetic subdivision into an Atlantic and a Mediterranean lineage, with genetic substructures within the Mediterranean Sea. Here, we produced experimental progeny crosses (N = 927) from broodstock sampled in four wild populations (North Atlantic, NAT; Western Mediterranean, WEM; North-Eastern Mediterranean, NEM; South-Eastern Mediterranean, SEM). We found less females than males in the progeny, both in the global dataset (32.5%) and within each paternal group (from 25.1% for NEM to 39.0% for WEM), with significant variation among populations, dams, and sires. Sex, body weight (BW), and body length (BL) showed moderate heritability (0.52 ± 0.17, 0.46 ± 0.17, 0.34 ± 0.15, respectively) and sex was genetically correlated with BW and BL, with rAsex/BW = 0.69 ± 0.12 and rA sex/BL = 0.66 ± 0.13. A weighted GWAS performed both on the global dataset and within each paternal group revealed a different genetic architecture of sex determination between Atlantic and Mediterranean populations (9 QTLs found in NAT, 7 in WEM, 5 in NEM, and 4 in SEM, with a cumulated variance explained of 27.04%, 21.87%, 15.89%, and 12.10%, respectively) and a more similar genetic architecture among geographically close populations compared to geographically distant populations, consistent with the hypothesis of a population-specific evolution of polygenic sex determination systems in different environments. 
PY 2019
PD MAY
SO Heredity
SN 0018-067X
PU Springer Nature America, Inc
VL 122
IS 5
UT 000464018400009
BP 612
EP 621
DI 10.1038/s41437-018-0157-z
ID 57609
ER

EF