FN Archimer Export Format PT J TI A community perspective on the concept of marine holobionts: current status, challenges, and future directions BT AF Dittami, Simon M Arboleda, Enrique AUGUET, Jean-Christophe Bigalke, Arite BRIAND, Enora Cardenas, Paco Cardini, Ulisse Decelle, Johan Engelen, Aschwin Eveillard, Damien Gachon, Claire MM Griffiths, Sarah Harder, Tilmann Kayal, Ehsan Kazamia, Elena Lallier, François H Media, Monica Marzinelli, Ezequiel M Morganti, Teresa Nunez Pons, Laura Prado, Soizik Pintado, José Saha, Mahasweta Selosse, Marc-André Skillings, Derek Stock, Willem Sunagawa, Shinichi Toulza, Eve Vorobev, Alexey Leblanc, Catherine Not, Fabrice AS 1:1;2:2;3:3;4:4;5:5;6:6;7:7;8:8;9:9;10:10;11:11;12:12;13:13;14:2;15:14;16:15;17:16;18:17,18,19;19:20;20:21;21:22;22:23;23:24,25;24:26,27;25:28;26:29;27:30;28:31;29:32;30:1;31:15; FF 1:;2:;3:;4:;5:PDG-ODE-DYNECO-PHYC;6:;7:;8:;9:;10:;11:;12:;13:;14:;15:;16:;17:;18:;19:;20:;21:;22:;23:;24:;25:;26:;27:;28:;29:;30:;31:; C1 UMR8227, Sorbonne Université, CNRS, Station Biologique de Roscoff, Roscoff, France FR2424, Sorbonne Université, CNRS, Station Biologique de Roscoff, Roscoff, France MARBEC, Université de Montpellier, CNRS, IFREMER, IRD, Montpellier, France Institute for Inorganic and Analytical Chemistry, Bioorganic Analytics, Friedrich-Schiller-Universität Jena, Jena, Germany Laboratoire Phycotoxines, Ifremer, Nantes, France Pharmacognosy, Department of Medicinal Chemistry, Uppsala Universitet, Uppsala, Sweden Integrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Napoli, Italy Laboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRA, Grenoble, France CCMAR, Universidade do Algarve, Faro, Portugal Laboratoire des Sciences Numériques de Nantes (LS2N), Université de Nantes, CNRS, Nantes, France Scottish Association for Marine Science Scottish Marine Institute, Oban, United Kingdom School of Science and the Environment, The Manchester Metropolitan University, Manchester, United Kingdom University of Bremen, Bremen, Germany Institut de Biologie, Ecole Normale Supérieure, Paris, France Adaptation and Diversity in the Marine Environment, Sorbonne Université, CNRS, Station Biologique de Roscoff, Roscoff, France Department of Biology, Pennsylvania State University, University Park, USA School of Life and Environmental Sciences, The University of Sydney, Sydney, Australia Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore, Singapore Sydney Institute of Marine Science, Mosman, Australia Max Planck Institute for Marine Microbiology, Bremen, Germany Section Biology and Evolution of Marine Organisms (BEOM), Stazione Zoologica Anton Dohrn (SZN), Napoli, Italy Molecules of Communication and Adaptation of Microorganisms (UMR 7245), National Museum of Natural History, CNRS, Paris, France Instituto de Investigaciones Marinas (IIM-CSIC), Vigo, Spain Benthic Ecology, Helmholtz Center for Ocean Research, Kiel, Germany School of Biological Sciences, University of Essex, Essex, United Kingdom Département Systématique et Evolution, Muséum national d’Histoire naturelle, Paris, France Faculty of Biology, University of Gdansk, Gdansk, Poland Philosophy Department, University of Pennsylvania, Philadelphia, USA Laboratory of Protistology & Aquatic Ecology, Department of Biology, Ghent University, Ghent, Belgium Department of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zürich, Zürich, Switzerland IHPE UMR 5244, Univ. Perpignan Via Domitia, CNRS, IFREMER, Univ. Montpellier, Perpignan, France Genoscope, CEA ‐ Institut de Biologie François Jacob, Evry, France C2 UNIV PARIS 06, FRANCE UNIV PARIS 06, FRANCE CNRS, FRANCE UNIV JENA, GERMANY IFREMER, FRANCE UNIV UPPSALA, SWEDEN STAZ ZOOL ANTON DOHRN, ITALY UNIV GRENOBLE ALPES, FRANCE UNIV ALGARVE, PORTUGAL UNIV NANTES, FRANCE SAMS SCOTLAND, UK UNIV MANCHESTER, UK UNIV BREMEN, GERMANY ENS, FRANCE UNIV PARIS 06, FRANCE UNIV PENN STATE, USA UNIV SYDNEY, AUSTRALIA UNIV NANYANG TECHNOL, SINGAPORE SIMS, AUSTRALIA MAX PLANCK INST, GERMANY STAZ ZOOL ANTON DOHRN, ITALY MNHN, FRANCE IIM CSIC, SPAIN GEOMAR, GERMANY UNIV ESSEX, UK MNHN, FRANCE UNIV GDANSK, POLAND UNIV PENNSYLVANIA, USA UNIV GHENT, BELGIUM ETH ZURICH, SWITZERLAND UNIV PERPIGNAN, FRANCE CEA, FRANCE SI NANTES SE PDG-ODE-DYNECO-PHYC UM MARBEC IHPE IN WOS Ifremer UPR WOS Cotutelle UMR DOAJ copubli-france copubli-europe copubli-univ-france copubli-int-hors-europe IF 3.061 TC 42 UR https://archimer.ifremer.fr/doc/00480/59209/82575.pdf LA English DT Article DE ;Evolution;Ecosystem services;Symbiosis;Host-microbiota interactions;Marine holobionts;Dysbiosis AB Host-microbe interactions play crucial roles in marine ecosystems, but we still have very little understanding of the mechanisms that govern these relationships, the evolutionary processes that shape them, and their ecological consequences. The holobiont concept is a renewed paradigm in biology that can help describe and understand these complex systems. It posits that a host and its associated microbiota, living together in a long-lasting relationship, form the holobiont, and have to be studied together, as a coherent biological and functional unit, in order to understand the biology, ecology and evolution of the organisms. Here we discuss critical concepts and opportunities in marine holobiont research and identify key challenges in the field. We highlight the potential economic, sociological, and environmental impacts of the holobiont concept in marine biological, evolutionary, and environmental sciences with comparisons to terrestrial science whenever appropriate. A deeper understanding of such complex systems, however, will require further technological and conceptual advances. The most significant challenge will be to bridge functional research on simple and tractable model systems and global approaches. This will require scientists to work together as an (inter)active community in order to address, for instance, ecological and evolutionary questions and the roles of holobionts in biogeochemical cycles. PY 2021 PD FEB SO Peerj SN 2167-8359 PU PeerJ VL 9 UT 000621591900009 DI 10.7717/peerj.10911 ID 59209 ER EF