FN Archimer Export Format
PT J
TI Complex Relationships between the Blue Pigment Marennine and Marine Bacteria of the Genus Vibrio
BT 
AF Falaise, Charlotte
   James, Adele
   Travers, Marie-Agnes
   Zanella, Marie
   Badawi, Myriam
   Mouget, Jean-Luc
AS 1:1;2:2,3;3:4;4:1;5:1;6:1;
FF 1:;2:PDG-RBE-PFOM;3:PDG-RBE-SGMM-LGPMM;4:;5:;6:;
C1 Laboratoire Mer Molécule Santé (EA 2160, FR CNRS 3473 IUML, Le Mans Université, F-72-000 Le Mans, France
   IFREMER, PDG-RBE-PFOM-LPI, Centre Bretagne, ZI de la Pointe du Diable, CS 10070, F-29280 Plouzané, France
   Sorbonne Université (UPMC Paris 06, CNRS, UMR 8227), Laboratoire de Biologie Intégrative des Modèles Marins, Station Biologique de Roscoff, F-26680 Roscoff, France
   IFREMER, PDG-RBE-SG2M-LGPMM, Station de La Tremblade, Ronce Les Bains, F-17390 La Tremblade, France
C2 UNIV LE MANS, FRANCE
   IFREMER, FRANCE
   UNIV PARIS 06, FRANCE
   IFREMER, FRANCE
SI BREST
   LA TREMBLADE
SE PDG-RBE-PFOM
   PDG-RBE-SGMM-LGPMM
IN WOS Ifremer UPR
   DOAJ
   copubli-france
   copubli-univ-france
IF 1.103
TC 13
UR https://archimer.ifremer.fr/doc/00484/59598/62602.pdf
   https://archimer.ifremer.fr/doc/00484/59598/62604.pdf
LA English
DT Article
DE ;antibacterial activity;diauxie;Haslea;hormesis;marennine;Vibrio
AB Marennine, the water-soluble blue pigment produced by the marine diatom Haslea ostrearia, is known to display antibacterial activities. Previous studies have demonstrated a prophylactic effect of marennine on bivalve larvae challenged with a pathogenic Vibrio splendidus, suggesting that the blue Haslea is a good candidate for applications in aquaculture as a source of a natural antimicrobial agent. Indeed, the genus Vibrio is ubiquitous in aquaculture ecosystems, and regular events of pathogenic invasion cause some of the biggest losses worldwide. To better characterize the effects of marennine on Vibrios, a panel of 30 Vibrio strains belonging to 10 different species was tested, including bivalve pathogenic species (e.g., Vibrio crassostreae and Vibrio harveyi). Vibrio strains were first exposed to 10 and 25 µg mL−1 of Blue Water (BW), a concentrated culture supernatant of H. ostrearia containing marennine. This screening evidenced a great diversity in responses, from growth stimulation to a total inhibition, at both the interspecific or intraspecific level. In a second series of experiments, 10 Vibrio strains were exposed to BW at concentrations ranging from 5 to 80 µg mL−1. The highest concentrations of BW did not systematically result in the highest growth inhibition as hormetic responses—opposite effects regarding the concentration—were occasionally evidenced. The relationships between marennine and Vibrio strains appear more complex than expected and justify further study—in particular, on the mechanisms of action—before considering applications as a natural prophylactic or antibiotic agent in aquaculture 
PY 2019
PD MAR
SO Marine Drugs
SN 1660-3397
PU MDPI AG
VL 17
IS 3
UT 000466398200024
DI 10.3390/md17030160
ID 59598
ER

EF