FN Archimer Export Format
PT J
TI Effect of prochloraz fungicide on biotransformation enzymes and oxidative stress parameters in three-spined stickleback (Gasterosteus aculeatus L.)
BT 
AF SANCHEZ, Wilfried
   PICCINI, Benjamin
   PORCHER, Jean-Marc
AS 1:1;2:1;3:1;
FF 1:;2:;3:;
C1 Inst Natl Environm Ind & Risques, Unite Evaluat Risques Ecotoxicol, Verneuil En Halatte, France.
C2 INERIS, FRANCE
IF 0.93
TC 26
UR https://archimer.ifremer.fr/doc/00500/61143/64693.pdf
LA English
DT Article
DE ;biomarkers;biotransformation enzymes;liver;oxidative stress;prochloraz;three-spined stickleback
AB The aim of this study was to characterize biomarker responses in three-spined sticklebacks exposed to prochloraz (Pcz). For this purpose, adult sticklebacks were exposed for 2 weeks to prochloraz at 0, 10, 50, 100 and 500 mu g/L prior to one week of depuration in clean water. At days 7, 14 and 21, several hepatic biomarkers were measured including 7-ethoxyresorufin-O-deethylase (EROD), glutathione-S-transferase (GST), glutathione peroxidase (GPx), catalase (CAT), total glutathione (GSH) content and thiobarbituric acid reactive substances (TBARS). Pcz induced a transient increase of antioxidant enzymes and a depletion of glutathione content during the first 7 days of exposure. This study showed that EROD activity and antioxidants were disrupted in a transient manner. GST was rapidly induced in a dose-dependent manner and this induction was persistent and observed also after depuration. GST appeared as a valuable biomarker to assess the exposure to Pcz. 
PY 2008
SO Journal Of Environmental Science And Health Part B-pesticides Food Contaminants And Agricultural Wastes
SN 0360-1234
PU Taylor & Francis Inc
VL 43
IS 1
UT 000252354800009
BP 65
EP 70
DI 10.1080/03601230701735151
ID 61143
ER

EF