FN Archimer Export Format
PT J
TI Spermatozoa motility in bivalves: Signaling, flagellar beating behavior, and energetics
BT 
AF BOULAIS, Myrina
   Demoy-Schneider, Marina
   Alavi, Sayyed Mohammad Hadi
   Cosson, Jacky
AS 1:1;2:2;3:3;4:4;
FF 1:;2:;3:;4:;
C1 University of Brest, CNRS, IRD, Ifremer, LEMAR, rue Dumont d’Urville, F-29280, Plouzané, France
   University of French Polynesia, UMR 241 EIO, BP 6570, 98702, Faa'a Aéroport, Tahiti, French Polynesia
   School of Biology, College of Science, University of Tehran, P.O. Box 14155-6455, Tehran, Iran
   South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Faculty of Fisheries and Protection of Waters, University of South Bohemia in České Budějovice, Vodňany 389 25, Czech Republic
C2 CNRS, FRANCE
   UNIV POLYNESIE FRANCAISE, FRANCE
   UNIV TEHRAN, IRAN
   UNIV SOUTH BOHEMIA, CZECH REPUBLIC
UM LEMAR
   EIO
IN WOS Cotutelle UMR
   copubli-europe
   copubli-int-hors-europe
   copubli-sud
IF 2.094
TC 12
UR https://archimer.ifremer.fr/doc/00502/61392/65055.pdf
LA English
DT Article
DE ;Adenosine triphosphate (ATP);Ion signaling;pH;Serotonin (5-HT);Spermatozoa motility;Spermatozoa velocity
AB Though bivalve mollusks are keystone species and major species groups in aquaculture production worldwide, gamete biology is still largely unknown. This review aims to provide a synthesis of current knowledge in the field of sperm biology, including spermatozoa motility, flagellar beating, and energy metabolism; and to illustrate cellular signaling controlling spermatozoa motility initiation in bivalves. Serotonin (5-HT) induces hyper-motility in spermatozoa via a 5-HT receptor, suggesting a serotoninergic system in the male reproductive tract that might regulate sperm physiology. Acidic pH and high concentration of K+ are inhibitory factors of spermatozoa motility in the testis. Motility is initiated at spawning by a Na+-dependent alkalization of intracellular pH mediated by a Na+/H+ exchanger. Increase of 5-HT in the testis and decrease of extracellular K+ when sperm is released in seawater induce hyperpolarization of spermatozoa membrane potential mediated by K+ efflux and associated with an increase in intracellular Ca2+ via opening of voltage-dependent Ca2+ channels under alkaline conditions. These events activate dynein ATPases and Ca2+/calmodulin-dependent proteins resulting in flagellar beating. It may be possible that 5-HT is also involved in intracellular cAMP rise controlling cAMP-dependent protein kinase phosphorylation in the flagellum. Once motility is triggered, flagellum beats in asymmetric wave pattern leading to circular trajectories of spermatozoa. Three different flagellar wave characteristics are reported, including “full”, “twitching”, and “declining” propagation of wave, which are described and illustrated in the present review. Mitochondrial respiration, ATP content, and metabolic pathways producing ATP in bivalve spermatozoa are discussed. Energy metabolism of Pacific oyster spermatozoa differs from previously studied marine species since oxidative phosphorylation synthetizes a stable level of ATP throughout 24-h motility period and the end of movement is not explained by a low intracellular ATP content, revealing different strategy to improve oocyte fertilization success. Finally, our review highlights physiological mechanisms that require further researches and points out some advantages of bivalve spermatozoa to extend knowledge on mechanisms of motility. 
PY 2019
PD SEP
SO Theriogenology
SN 0093-691X
PU Elsevier BV
VL 136
UT 000476579700004
BP 15
EP 27
DI 10.1016/j.theriogenology.2019.06.025
ID 61392
ER

EF