FN Archimer Export Format
PT J
TI Water-soluble poly(3-hydroxyalkanoate) sulfonate: versatile biomaterials used as coatings for highly porous nano-MOF
BT 
AF JAIN, Caroline
   Li, Xue
   HOUEL RENAULT, Ludivine
   Modjinou, Tina
   SIMON COLIN, Christelle
   Gref, Ruxandra
   Renard, Estelle
   Langlois, Valérie
AS 1:1,2;2:3;3:4;4:1;5:2;6:3;7:1;8:1;
FF 1:PDG-REM-EEP-LMEE;2:;3:;4:;5:PDG-REM-EEP-LMEE;6:;7:;8:;
C1 Institut de Chimie et des Matériaux Paris-Est, UPEC-CNRS, 2 rue Henry Dunant, 94320 Thiais, France
   Ifremer, UMR 6197, Laboratoire de Microbiologie des Environnements Extrêmes (LM2E), Technopôle Pointe du Diable, 29280 Plouzané, France
   Institut des Sciences Moléculaires d’Orsay, UMR 8214, CNRS-UPS, Rue André Rivière, 91405 Orsay, France
   Centre Laser de l’Université Paris-Sud (CLUPS/LUMAT), CNRS-UPS-IOGS, Université Paris-Saclay, 91405 Orsay, France
C2 UNIV PARIS EST, FRANCE
   IFREMER, FRANCE
   UNIV PARIS SUD, FRANCE
   UNIV PARIS SUD, FRANCE
SI BREST
SE PDG-REM-EEP-LMEE
UM BEEP-LM2E
IN WOS Ifremer UMR
   copubli-france
   copubli-univ-france
IF 6.092
TC 17
UR https://archimer.ifremer.fr/doc/00505/61677/65620.pdf
LA English
DT Article
AB Water soluble poly(3-hydroxyalkanoate) containing ionic groups was designed by two successive photo-activated thiol-ene reactions. Sodium-3-mercapto-1-ethanesulfonate (SO3-) and poly(ethylene glycol) methyl ether thiol (PEG) were grafted onto poly(3-hydroxyoctanoate-co-3-hydroxyundecenoate) PHO(67)U(33) to both introduce ionic groups and hydrophilic moieties. The grafted copolymers PHO(67)SO3-(20)PEG(13) were then used as biocompatible coatings of nano-Metal Organic Frameworks surface. Scanning Electron Microscopy and Scanning Transmission Electron Microscopy coupled with Energy Dispersive X-ray characterizations have clearly demonstrated the presence of the copolymer on the MOF surface. These coated nano-MOF are stable in aqueous and physiological fluids. Cell proliferation and cytotoxicity tests performed on murine macrophages J774.A1 revealed no cytotoxic side effect. Thus, biocompatibility and stability of these novel hybrid porous MOF structures encourage their use in the development of effective therapeutic nanoparticles. 
PY 2019
PD SEP
SO Biomacromolecules
SN 1525-7797
PU American Chemical Society (ACS)
VL 20
IS 9
UT 000485211000012
BP 3324
EP 3332
DI 10.1021/acs.biomac.9b00870
ID 61677
ER

EF