FN Archimer Export Format
PT C
TI Mining of the biosynthetic mechanisms of Vibrio spp. polysaccharides and potential role in biofilm formation
BT 
AF VERREZ-BAGNIS, Veronique
   SOREE, Marion
   PASSERINI, Delphine
   KOLYPCZUK, Laetitia
   MARCHAND, Laetitia
   BONNETOT, Sandrine
   FECAMP, Florian
   LOZACH, Solen
   HERVIO HEATH, Dominique
   DELBARRE LADRAT, Christine
AS 1:1;2:1;3:1;4:1;5:1;6:1;7:1;8:1;9:1;10:1;
FF 1:PDG-RBE-BRM-LEMMMB;2:PDG-RBE-SGMM-LSEM;3:PDG-RBE-BRM-LEMMMB;4:PDG-RBE-BRM-LEMMMB;5:PDG-RBE-BRM-LEMMMB;6:PDG-RBE-BRM-LEMMMB;7:;8:PDG-RBE-SGMM-LSEM;9:PDG-RBE-SGMM-LSEM;10:PDG-RBE-BRM-LEMMMB;
C2 IFREMER, FRANCE
SI NANTES
   BREST
SE PDG-RBE-BRM-LEMMMB
   PDG-RBE-SGMM-LSEM
UR https://archimer.ifremer.fr/doc/00514/62605/66965.pdf
LA English
DT Poster
AB Vibrio spp. are ubiquitous marine bacteria that are ecologically and metabolically diverse members of planktonic and animal associated microbial communities. They encompass the ancient and well-studied human pathogen, Vibrio cholerae, and two other human pathogens, V. vulnificus and V. parahaemolyticus, as well as some less thoroughly characterized animal pathogens. Virulence is based on a wide diversity of mechanisms involved in motility and host colonization, in ability to persist and develop, and in damage generation. Polysaccharides may play major roles in virulence and are major components of extracellular polymeric matrix synthesized upon biofilm growth. They may also exhibit biological features, especially those similar to animal-derived glycosaminoglycans (GAG). Bacterial polysaccharides include EPSs which are released to the surrounding medium, and two surface polysaccharides: lipopolysaccharides (LPS) with an O-antigen polysaccharide linked to the Lipid A core complex and capsular polysaccharides (CPS) with K-antigen. Diversity of biosynthetic pathways involved in glycopolymers biosynthesis in Vibrio spp. was analysed through in silico identification of genes encoding CAZYmes and comparative genomic approaches. In parallel, ability to form biofilm and extracellular matrix composition is studied. The aim is to provide a better knowledge of the polysaccharide gene cluster importance and to facilitate discovery of new bioactive carbohydrate compounds. 
PY 2019
PD MAY
ID 62605
ER

EF