FN Archimer Export Format
PT J
TI Long-term exposure to near-future ocean acidification does not affect the expression of neurogenesis- and synaptic transmission-related genes in the olfactory bulb of European sea bass (Dicentrarchus labrax)
BT 
AF Mazurais, David
   Servili, Arianna
   Le Bayon, Nicolas
   Gislard, Sebastien
   Madec, Lauriane
   Zambonino-Infante, Jose-Luis
AS 1:1;2:1;3:1;4:1;5:1;6:1;
FF 1:PDG-RBE-PFOM-LARN;2:PDG-RBE-PFOM-LARN;3:PDG-RBE-PFOM-LARN;4:;5:PDG-RBE-PFOM-LARN;6:PDG-RBE-PFOM-LARN;
C1 IFREMER, Univ Brest, CNRS, IRD, LEMAR, 29280, Brest, Plouzané, France
C2 IFREMER, FRANCE
SI BREST
SE PDG-RBE-PFOM-LARN
UM LEMAR
IN WOS Ifremer UMR
IF 2.2
TC 7
UR https://archimer.ifremer.fr/doc/00606/71786/70315.pdf
LA English
DT Article
DE ;Ocean acidification;Long-term exposure;Gene expression;Olfactory bulbs
AB The decrease in ocean pH that results from the increased concentration of dissolved carbon dioxide (CO2) is likely to influence many physiological functions in organisms. It has been shown in different fish species that ocean acidification (OA) mainly affects sensory systems, including olfaction. Impairment of olfactory function may be due to a dysfunction of the GABAergic system and to an alteration of neuronal plasticity in the whole brain and particularly in olfactory bulbs. Recent studies revealed that OA-driven effects on sensory systems are partly mediated by the regulation of the expression of genes involved in neurotransmission and neuronal development. However, these studies were performed in fish exposed to acidified waters for short periods, of only a few days. In the present paper, we investigated whether such effects could be observed in adult (4-years old) European sea bass (Dicentrarchus labrax) exposed to two hypercapnic and acidified conditions (PCO2 ≈ 980 µatm; pH total = 7.7 and PCO2 ≈ 1520 µatm; pH total = 7.5) from the larval stage. In a first approach, we analyzed by qPCR the expression of five genes involved in neurogenesis (DCX) or expressed in GABAergic (Gabra3), glutamatergic (Gria1) or dopaminergic (TH and DDC) neurons in the olfactory bulbs. The tested experimental conditions did not change the expression of any of the five genes. This result would indicate that a potential disruption of the olfactory function of sea bass exposed for a long term to near-future OA, either occurs at a level other than the transcriptional one or involves other actors of the sensory function. 
PY 2020
PD MAR
SO Journal Of Comparative Physiology B-biochemical Systems And Environmental Physiology
SN 0174-1578
PU Springer Science and Business Media LLC
VL 190
IS 2
UT 000514971500002
BP 161
EP 167
DI 10.1007/s00360-019-01256-2
ID 71786
ER

EF