FN Archimer Export Format
PT J
TI Salt Shock Responses of Microcystis Revealed through Physiological, Transcript, and Metabolomic Analyses
BT 
AF Georges des Aulnois, Maxime
   Réveillon, Damien
   ROBERT, Elise
   Caruana, Amandine
   Briand, Enora
   Guljamow, Arthur
   Dittmann, Elke
   Amzil, Zouher
   Bormans, Myriam
AS 1:1;2:1;3:1;4:1;5:1;6:2;7:2;8:1;9:3;
FF 1:PDG-ODE-DYNECO-PHYC;2:PDG-ODE-DYNECO-PHYC;3:;4:PDG-ODE-DYNECO-PHYC;5:PDG-ODE-DYNECO-PHYC;6:;7:;8:PDG-ODE-DYNECO-PHYC;9:;
C1 IFREMER-Phycotoxins Laboratory, IFREMER, F-44311 Nantes, France
   Department of Microbiology, Institute for Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Str. 24/25, 14476 Potsdam, Germany
   UMR CNRS 6553 ECOBIO, University of Rennes, 35042 Rennes, France
C2 IFREMER, FRANCE
   UNIV POTSDAM, GERMANY
   UNIV RENNES, FRANCE
SI NANTES
SE PDG-ODE-DYNECO-PHYC
IN WOS Ifremer UPR
   DOAJ
   copubli-france
   copubli-europe
   copubli-univ-france
IF 2.13
TC 12
UR https://archimer.ifremer.fr/doc/00615/72689/71692.pdf
   https://archimer.ifremer.fr/doc/00615/72689/71693.pdf
LA English
DT Article
DE ;Microcystis aeruginosa;microcystin;salt stress;metabolomic;transcript
AB The transfer of Microcystis aeruginosa from freshwater to estuaries has been described worldwide and salinity is reported as the main factor controlling the expansion of M. aeruginosa to coastal environments. Analyzing the expression levels of targeted genes and employing both targeted and non-targeted metabolomic approaches, this study investigated the e ect of a sudden salt increase on the physiological and metabolic responses of two toxic M. aeruginosa strains separately isolated from fresh and brackish waters, respectively, PCC 7820 and 7806. Supported by di erences in gene expressions and metabolic profiles, salt tolerance was found to be strain specific. An increase in salinity decreased the growth of M. aeruginosa with a lesser impact on the brackish strain. The production of intracellular microcystin variants in response to salt stress correlated well to the growth rate for both strains. Furthermore, the release of microcystins into the surrounding medium only occurred at the highest salinity treatment when cell lysis occurred. This study suggests that the physiological responses of M. aeruginosa involve the accumulation of common metabolites but that the intraspecific salt tolerance is based on the accumulation of specific metabolites. While one of these was determined to be sucrose, many others remain to be identified. Taken together, these results provide evidence that M. aeruginosa is relatively salt tolerant in the mesohaline zone and microcystin (MC) release only occurs when the capacity of the cells to deal with salt increase is exceeded. 
PY 2020
PD MAR
SO Toxins
SN 2072-6651
PU MDPI AG
VL 12
IS 3
UT 000525009500020
DI 10.3390/toxins12030192
ID 72689
ER

EF