FN Archimer Export Format
PT J
TI Anti-Biofilm Effect of Biodegradable Coatings Based on Hemibastadin Derivative in Marine Environment
BT 
AF LE NORCY, Tiffany
   NIEMANN, Hendrik
   PROKSCH, Peter
   LINOSSIER, Isabelle
   VALLEE-REHEL, Karine
   HELLIO, Claire
   FAY, Fabienne
AS 1:1;2:2;3:2;4:1;5:1;6:3;7:1;
FF 1:;2:;3:;4:;5:;6:;7:;
C1 Univ Bretagne Sud, Inst Univ Europeen Mer, Lab Biotechnol & Chim Marines, F-56100 Lorient, France.
   Heinrich Heine Univ Dusseldorf, Inst Pharmaceut Biol & Biotechnol, D-40225 Dusseldorf, Germany.
   Univ Bretagne Occidentale, Inst Europeen Mer, LEMAR UMR 6539, Biodimar, F-29200 Brest, France.
C2 UBS, FRANCE
   UNIV DUSSELDORF, GERMANY
   UBO, FRANCE
UM LEMAR
IN DOAJ
IF 3.687
TC 11
UR https://archimer.ifremer.fr/doc/00616/72812/72626.pdf
LA English
DT Article
DE ;antifouling;biodegradable coating;hemibastadin;sponges;marine bacteria;microalgae
AB Dibromohemibastadin-1 (DBHB) is an already known potent inhibitor of blue mussel phenoloxidase (which is a key enzyme involved in bioadhesion). Within this study, the potentiality of DBHB against microfouling has been investigated. The activity of DBHB was evaluated on key strains of bacteria and microalgae involved in marine biofilm formation and bioassays assessing impact on growth, adhesion and biofilm formation were used. To assess the efficiency of DBHB when included in a matrix, DBHB varnish was prepared and the anti-microfouling activity of coatings was assessed. Both in vitro and in situ immersions were carried out. Confocal Laser Scanning Microscopy (CLSM) was principally used to determine the biovolume and average thickness of biofilms developed on the coatings. Results showed an evident efficiency of DBHB as compound and varnish to reduce the biofilm development. The mode of action seems to be based principally on a perturbation of biofilm formation rather than on a biocidal activity in the tested conditions. 
PY 2017
PD JUN
SO International Journal Of Molecular Sciences
SN 1422-0067
PU Mdpi Ag
VL 18
IS 7
UT 000408746800189
DI 10.3390/ijms18071520
ID 72812
ER

EF