FN Archimer Export Format PT J TI Glycoglycerolipids From Sargassum vulgare as Potential Antifouling Agents BT AF Plouguerné, Erwan de Souza, Lauro M. Sassaki, Guilherme L. Hellio, Claire Trepos, Rozenn da Gama, Bernardo A. P. Pereira, Renato Crespo Barreto-Bergter, Eliana AS 1:1,2;2:3;3:4;4:5;5:;6:1;7:1,2;8:6; FF 1:;2:;3:;4:;5:;6:;7:;8:; C1 Department of Marine Biology, Biology Institute, Universidade Federal Fluminense, Niterói, Brazil Instituto de Pesquisas Jardim Botânico do Rio de Janeiro, Rio de Janeiro, Brazil Instituto de Pesquisa Pelé Pequeno Príncipe, Rebouças, Curitiba, Brazil Department of Biochemistry and Molecular Biology, Paraná Federal University, Curitiba, Brazil Univ Brest, Laboratoire des Sciences de l’Environnement MARin (LEMAR), CNRS, IRD, Ifremer, France Department of General Microbiology, Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil C2 UNIV FED FLUMINENSE UFF, BRAZIL INST PESQ JARDIM BOTANICO RIO JANEIRO, BRAZIL INST PES PELE PEQUENO PRINCIPE, BRAZIL UNIV FED PARANA, BRAZIL UBO, FRANCE UNIV FED RIO DE JANEIRO UFRJ, BRAZIL UM LEMAR IN WOS Cotutelle UMR DOAJ copubli-int-hors-europe copubli-sud IF 5.247 TC 15 UR https://archimer.ifremer.fr/doc/00618/73053/72168.pdf LA English DT Article DE ;Sargassum vulgare;glycoglycerolipids;antifouling;microfouling;macroalgae AB Unraveling new environmentally friendly antifouling (AF) agents is one of the major quests currently facing marine biotechnology. Marine macroalgae represent a rich source of new compounds with promising biological properties, including AF activity, but most of the macroalgal compounds studied to date are terpenoids or polyphenolics. The aim of this work was to investigate the possible AF role played by a usually neglected class of marine natural products: glycolipids (monogalactosyldiacylglycerols – MGDG, digalactosyldiacylglycerols – DGDG and sulfoquinovosyldiacylglycerols – SQDG) isolated from the Phaeophyceae Sargassum vulgare collected along the coast of south-eastern Brazil. Among the 18 extracts, fractions and sub-fractions tested, 3 sub-fractions demonstrated particularly promising AF activity toward the growth inhibition of marine bacteria and microalgae: F3III117, F4II70a, and F4II70b. The main compounds present in these fractions were identified as MGDG, DGDG, and SQDG, respectively. These results highlight the potential of glycoglycerolipids from S. vulgare as new promising antifouling agents. PY 2020 PD MAR SO Frontiers In Marine Science SN 2296-7745 PU Frontiers Media SA VL 7 IS 116 UT 000519752500001 DI 10.3389/fmars.2020.00116 ID 73053 ER EF