FN Archimer Export Format
PT J
TI Contribution of Viral Genomic Diversity to Oyster Susceptibility in the Pacific Oyster Mortality Syndrome
BT 
AF Delmotte, Jean
   Chaparro, Cristian
   Galinier, Richard
   de Lorgeril, Julien
   Petton, Bruno
   Stenger, Pierre-Louis
   Vidal-Dupiol, Jeremie
   Destoumieux-Garzon, Delphine
   Gueguen, Yannick
   Montagnani, Caroline
   Escoubas, Jean Michel
   Mitta, Guillaume
AS 1:3;2:4;3:4;4:1;5:2;6:1;7:1;8:3;9:1;10:1;11:3;12:4;
FF 1:;2:;3:;4:PDG-RBE-IHPE;5:PDG-RBE-PFOM-LPI;6:;7:PDG-RBE-IHPE;8:;9:PDG-RBE-IHPE;10:PDG-RBE-IHPE;11:;12:;
C1 IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia, Montpellier, France
   LEMAR UMR 6539, Université de Bretagne Occidentale, CNRS, IRD, Ifremer, Argenton-en-Landunvez, France
   IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia, Montpellier, France
   IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia, Montpellier, France
C2 IFREMER, FRANCE
   IFREMER, FRANCE
   CNRS, FRANCE
   UNIV MONTPELLIER, FRANCE
SI MONTPELLIER
   ARGENTON
SE PDG-RBE-IHPE
   PDG-RBE-PFOM-LPI
UM LEMAR
   IHPE
IN WOS Ifremer UMR
   WOS Cotutelle UMR
   DOAJ
   copubli-france
   copubli-univ-france
IF 3.941
TC 12
UR https://archimer.ifremer.fr/doc/00643/75533/76414.pdf
   https://archimer.ifremer.fr/doc/00643/75533/76415.pptx
   https://archimer.ifremer.fr/doc/00643/75533/76416.pptx
   https://archimer.ifremer.fr/doc/00643/75533/76417.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76418.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76419.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76420.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76421.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76422.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76423.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76424.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76425.xlsx
   https://archimer.ifremer.fr/doc/00643/75533/76426.xlsx
LA English
DT Article
DE ;Crassostrea gigas;herpesvirus diversity;genotype-genotype interactions;oyster genetic background;viral populations
AB Juvenile Pacific oysters (Crassostrea gigas) are subjected to recurrent episodes of mass mortalities that constitute a threat for the oyster industry. This mortality syndrome named “Pacific Oyster Mortality Syndrome” (POMS) is a polymicrobial disease whose pathogenesis is initiated by a primary infection by a variant of an Ostreid herpes virus named OsHV-1 μVar. The characterization of the OsHV-1 genome during different disease outbreaks occurring in different geographic areas has revealed the existence of a genomic diversity for OsHV-1 μVar. However, the biological significance of this diversity is still poorly understood. To go further in understanding the consequences of OsHV-1 diversity on POMS, we challenged five biparental families of oysters to two different infectious environments on the French coasts (Atlantic and Mediterranean). We observed that the susceptibility to POMS can be different among families within the same environment but also for the same family between the two environments. Viral diversity analysis revealed that Atlantic and Mediterranean POMS are caused by two distinct viral populations. Moreover, we observed that different oyster families are infected by distinct viral populations within a same infectious environment. Altogether these results suggest that the co-evolutionary processes at play between OsHV-1 μVar and oyster populations have selected a viral diversity that could facilitate the infection process and the transmission in oyster populations. These new data must be taken into account in the development of novel selective breeding programs better adapted to the oyster culture environment. 
PY 2020
PD JUN
SO Frontiers In Microbiology
SN 1664-302X
PU Frontiers Media SA
VL 11
UT 000555902100001
DI 10.3389/fmicb.2020.01579
ID 75533
ER

EF