TY - JOUR T1 - Growth Performance and Adaptability of European Sea Bass (Dicentrarchus labrax) Gut Microbiota to Alternative Diets Free of Fish Products A1 - Pérez-Pascual,David A1 - Estellé,Jordi A1 - Dutto,Gilbert A1 - Rodde,Charles A1 - Bernardet,Jean-François A1 - Marchand,Yann A1 - Duchaud,Eric A1 - Przybyla,Cyrille A1 - Ghigo,Jean-Marc AD - Unité de Génétique des Biofilms, Institut Pasteur, UMR CNRS2001, 75015 Paris, France AD - AgroParisTech, GABI, Université Paris-Saclay, INRAE, 78350 Jouy-en-Josas, France AD - Laboratoire Service d’Expérimentations Aquacoles, Ifremer, 34250 Palavas les flots, France AD - MARBEC, IRD, IFREMER, Univ Montpellier, CNRS, Laboratoire Adaptation, adaptabilité, des animaux et des systèmes Ifremer, 34250 Palavas les flots, France AD - Virologie et Immunologie Moléculaires, INRAE, Université Paris-Saclay, 78350 Jouy-en-Josas, France AD - Le Gouessant, F-22402 Lamballe, France UR - https://archimer.ifremer.fr/doc/00646/75830/ DO - 10.3390/microorganisms8091346 KW - European sea bass KW - fish gut microbiota KW - bacteria N2 - Innovative fish diets made of terrestrial plants supplemented with sustainable protein sources free of fish-derived proteins could contribute to reducing the environmental impact of the farmed fish industry. However, such alternative diets may influence fish gut microbial community, health, and, ultimately, growth performance. Here, we developed five fish feed formulas composed of terrestrial plant-based nutrients, in which fish-derived proteins were substituted with sustainable protein sources, including insect larvae, cyanobacteria, yeast, or recycled processed poultry protein. We then analyzed the growth performance of European sea bass (Dicentrarchus labrax L.) and the evolution of gut microbiota of fish fed the five formulations. We showed that replacement of 15% protein of a vegetal formulation by insect or yeast proteins led to a significantly higher fish growth performance and feed intake when compared with the full vegetal formulation, with feed conversion ratio similar to a commercial diet. 16S rRNA gene sequencing monitoring of the sea bass gut microbial community showed a predominance of Proteobacteria, Firmicutes, Actinobacteria, and Bacteroidetes phyla. The partial replacement of protein source in fish diets was not associated with significant differences on gut microbial richness. Overall, our study highlights the adaptability of European sea bass gut microbiota composition to changes in fish diet and identifies promising alternative protein sources for sustainable aquafeeds with terrestrial vegetal complements. Y1 - 2020/09 PB - MDPI AG JF - Microorganisms SN - 2076-2607 VL - 8 IS - 9 ID - 75830 ER -