FN Archimer Export Format
PT J
TI Responses to iron oxide and zinc oxide nanoparticles in echinoderm embryos and microalgae: uptake, growth, morphology, and transcriptomic analysis
BT 
AF Genevière, Anne-Marie
   Derelle, Evelyne
   Escande, Marie-Line
   Grimsley, Nigel
   Klopp, Christophe
   Ménager, Christine
   Michel, Aude
   Moreau, Hervé
AS 1:1;2:1,2;3:1;4:1;5:3;6:4;7:4;8:1;
FF 1:;2:;3:;4:;5:;6:;7:;8:;
C1 Sorbonne Université, CNRS, Biologie Intégrative des Organismes Marins, BIOM, Banyuls-sur-Mer, France
   Univ Brest, CNRS, IRD, Ifremer, LEMAR, Plouzane, France
   INRA, Plateforme Bioinformatique Toulouse, Midi Pyrenees UBIA, Castanet Tolosan, France
   Sorbonne Université, CNRS, PHysico-chimie des Electrolytes et Nanosystèmes InterfaciauX, PHENIX, Paris, France
C2 UNIV SORBONNE, FRANCE
   CNRS, FRANCE
   INRA, FRANCE
   UNIV SORBONNE, FRANCE
UM LEMAR
IN WOS Cotutelle UMR
   copubli-france
   copubli-univ-france
IF 5.913
TC 12
UR https://archimer.ifremer.fr/doc/00654/76607/83368.pdf
LA English
DT Article
DE ;Nanoparticles;toxicity;marine organisms;metal oxide;transcriptomics
AB We investigated the toxicity of Iron oxide and Zinc oxide engineered nanoparticles (ENPs) on Paracentrotus lividus sea urchin embryos and three species of microalgae. Morphological responses, internalization, and potential impacts of Fe2O3 and ZnO ENPs on physiology and metabolism were assessed. Both types of ENPs affected P. lividus larval development, but ZnO ENPs had a much stronger effect. While growth of the alga Micromonas commoda was severely impaired by both ENPs, Ostreococcus tauri or Nannochloris sp. were unaffected. Transmission electron microscopy showed the internalization of ENPs in sea urchin embryonic cells while only nanoparticle interaction with external membranes was evidenced in microalgae, suggesting that marine organisms react in diverse ways to ENPs. Transcriptome-wide analysis in P. lividus and M. commoda showed that many different physiological pathways were affected, some of which were common to both species, giving insights about the mechanisms underpinning toxic responses 
PY 2020
PD NOV
SO Nanotoxicology
SN 1743-5390
PU Informa UK Limited
VL 14
IS 10
UT 000577361100001
BP 1342
EP 1361
DI 10.1080/17435390.2020.1827074
ID 76607
ER

EF