FN Archimer Export Format
PT J
TI An Integrated Biomarker Approach Using Flounder to Improve Chemical Risk Assessments in the Heavily Polluted Seine Estuary
BT 
AF Borcier, Elodie
   Charrier, Gregory
   Couteau, Jérôme
   Maillet, Géraldine
   Le Grand, Fabienne
   Bideau, Antoine
   Waeles, Mathieu
   Le Floch, Stephane
   Amara, Rachid
   Pichereau, Vianney
   Laroche, Jean
AS 1:1;2:1;3:2;4:2;5:5;6:1;7:1;8:3;9:4;10:1;11:1;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:;11:;
C1 Laboratoire des Sciences de l’Environnement Marin, Institut Universitaire Européen de la Mer, Université de Bretagne Occidentale, UMR 6539 CNRS/UBO/IRD/Ifremer, Place Nicolas Copernic, 29280 Plouzané, France
   TOXEM, 12 rue des 4 saisons, 76290 Montivilliers, France
   CEDRE, 715 rue Alain Colas, 29200 Brest, France
   Laboratoire d’Océanologie et Géosciences UMR 8187, Université du Littoral, 28 Avenue du Maréchal Foch, 62930 Wimereux, France
   Laboratoire des Sciences de l’Environnement Marin, Institut Universitaire Européen de la Mer, Université de Bretagne Occidentale, UMR 6539 CNRS/UBO/IRD/Ifremer, Place Nicolas Copernic, 29280 Plouzané, France
C2 UBO, FRANCE
   TOXEM, FRANCE
   CEDRE, FRANCE
   UNIV LITTORAL COTE D'OPALE, FRANCE
   CNRS, FRANCE
UM LEMAR
IN WOS Cotutelle UMR
   DOAJ
   copubli-france
   copubli-univ-france
TC 6
UR https://archimer.ifremer.fr/doc/00658/76981/78238.pdf
LA English
DT Article
DE ;Platichthys flesus;estuaries;biomarkers;bioenergetics;polar lipids;population genetics
AB The objective of this study was to develop an integrative approach in ecotoxicology (from biomarkers to population genetics) to assess the ecological status of fish populations. Flounders (Platichthys flesus) collected after the spawning season in the heavily polluted Seine estuary were compared with the moderately polluted Bay of Douarnenez. The muscle energetic reserves were highly depleted in Seine vs. Douarnenez fish. The Seine fish displaying a reduced capacity to manage the oxidative stress and a higher energetic metabolism. An increase in the content of muscle membrane phospholipids (sphingomyelin, phosphatidylserine, free sterols) was detected in the Seine vs. Douarnenez fish. The data integration allowed to hypothesize relationships between membrane phospholipids, xenobiotic metabolism, bioenergetics, and antioxidant defence. The genetic diversity considering neutral markers was maintained in the heavily polluted Seine population compared with the Douarnenez population. Finally, we suggest that the high physiological cost of tolerance to toxicants in the Seine flounder population could compromise its capacity to respond in the future to an additional stressor like warming waters in shallow depth. Thus, this population could be submitted to an ecological risk. 
PY 2020
PD DEC
SO Journal Of Xenobiotics
SN 2039-4705
PU MDPI AG
VL 10
IS 2
UT 000602982900001
BP 14
EP 35
DI 10.3390/jox10020004
ID 76981
ER

EF