FN Archimer Export Format
PT J
TI Non-Essential Trace Elements Dietary Exposure in French Polynesia: Intake Assessment, Nail Bio Monitoring and Thyroid Cancer Risk
BT 
AF Zidane, Monia
   Ren, Yen
   Xhaard, Constance
   Leufroy, Axelle
   Côte, Suzanne
   Dewailly, Eric
   Noël, Laurent
   Guérin, Thierry
   Bouisset, Patrick
   Bernagout, Solène
   Paaoafaite, John
   Iltis, Jacques
   Taquet, Marc
   Suhas, Eric
   Rachédi, Frédérique
   Boissin, Jean Louis
   Sebbag, Joseph
   Shan, Larrys
   Bost-Bezeaud, Frédérique
   Petitdidier, Patrice
   Rubino, Carole
   Gardon, Jacques
   de Vathaire, Florent
AS 1:1,2,3;2:1,2,3;3:1,2,3;4:4;5:5;6:5;7:4;8:4;9:6;10:6;11:7;12:8;13:8;14:9;15:10;16:11;17:12;18:13;19:14;20:14;21:1,2,3;22:15;23:1,2,3;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:;11:;12:;13:;14:;15:;16:;17:;18:;19:;20:;21:;22:;23:;
C1 Radiation Epidemiology Group, Centre for Research in Epidemiology and Population Health (CESP), UMR 1018 Inserm, Villejuif, France.
   Gustave Roussy, Villejuif, France.
   Faculty of Medicine, University Paris Sud 11, Le Kremlin-Bicêtre, France.
   Université de Paris-Est, Anses, Laboratory for food safety, F94700 Maisons-Alfort, France.
   Area of population health and optimal health practices, CHU de Québec Research Center, Québec, Canada.
   Laboratoire d’Étude et de Surveillance de l’Environnement, Institut de Radioprotection et de Sécurité Nucléaire, Papeete, Tahiti, French Polynesia.
   Institute of Research for Development (IRD), Papeete, Tahiti, French Polynesia.
   Institute of Research for Development (IRD), Laboratoires d’études rurales, Montpellier, France.
   Non-Communicable Diseases Unit, Oceanian Islands Ecosystems-UMR 241, Louis Malardé Institute, Papeete, Tahiti, French Polynesia.
   Endocinology Unit, Territorial Hospital Taaone, Papeete, Tahiti, French Polynesia.
   IPRAME, Papeete, Tahiti, French Polynesia.
   Paofai Clinic, Papeete, Tahiti, French Polynesia.
   Endocrinologist, Papeete, Tahiti, French Polynesia.
   Laboratory of Anatomy and Cytopathology, Territorial Hospital Taaone, Papeete, Tahiti, French Polynesia.
   Institut de Recherche pour le Développement (IRD), Hydrosciences (HSM), Montpellier, France.
C2 INSERM, FRANCE
   GUSTAVE ROUSSY, FRANCE
   UNIV PARIS SUD, FRANCE
   UNIV PARIS-EST, FRANCE
   CHU QUEBEC, CANADA
   IRSN, FRANCE
   IRD, FRANCE
   IRD, FRANCE
   INST LOUIS MALARDE, FRANCE
   HOP TAAONE, FRANCE
   IPRAME, FRANCE
   PAOFAI CLINIC, FRANCE
   Endocrinologist, Papeete, Tahiti, French Polynesia.
   HOP TAAONE, FRANCE
   IRD, FRANCE
SI TAHITI
SE IRSN-LESE
UM EIO
TC 0
UR https://archimer.ifremer.fr/doc/00660/77190/78617.pdf
LA English
DT Article
DE ;Thyroid cancer;nETE;diet;fingernail;case-control study
AB Background: In French Polynesia, thyroid cancer mortality and incidence is reported to be the highest in the world. Excessive levels of non-essential trace elements (nETE) in the body are associated with several types of cancer. Objective: The present study aims to provide quantitative information on food contamination by mercury (Hg), lead (Pb), arsenic (As) and cadmium (Cd) in French Polynesia and its potential correlation with measurements performed in fingernails of Polynesians, and then to investigate the potential association between these nETE and different thyroid cancer risks. Methods: The study population included 229 interviewed cases and 373 interviewed controls We performed a descriptive analysis of Polynesian food and examined the association between thyroid cancer risk and daily intake levels of nETE and with fingernail nETE levels. Results: Hg contamination was mainly present in sea products, Pb contamination was present in almost all samples, Cd was detectable in starchy food and As was detectable in all sea products. No patient exceeded dietary contamination WHO limits for Pb, 2 participants exceeded it for Hg and 3 individuals (0.5%) for cadmium. In fingernail clippings, the most detectable pollutant was Pb (553 participants), then Hg (543 participants) then Cd (only in 130 participants). Thyroid cancer risk was increased more than 4 times by Pb daily intake in patients with a history of cancer in first-degree relatives than in ones without (p for interaction =0.01), and 2 times more in women with more than 3 pregnancies than in those with none or less (p for interaction =0.005); it was also increased following As intake by more than 30% in patients with a history of cancer in first-degree relatives than in ones without (p for interaction =0.05). Conclusion: Locally produced foods are not a source of nETE exposure in French Polynesia. Dieatry nETE exposure and fingernail nETE concentration are not associated to differentiated thyroid cancer risk. No correlation found between nETE dietary exposure and fingernail nETE concentration. 
PY 2019
PD FEB
SO Asian Pacific Journal of Cancer Prevention
SN 2476-762X
PU EpiSmart Science Vector Ltd
VL 20
IS 2
BP 355
EP 367
DI 10.31557/APJCP.2019.20.2.355
ID 77190
ER

EF