FN Archimer Export Format PT J TI Chemotaxonomy and cytotoxicity of the liverwort Porella Viridissima BT AF Métoyer, Benjamin Lebouvier, Nicolas Hnawia, Edouard Thouvenot, Louis Wang, Fengrui Harinantenaina Rakotondraibe, Liva Raharivelomanana, Phila Asakawa, Yoshinori Nour, Mohammed AS 1:1,2;2:1;3:1;4:3;5:4;6:4;7:5;8:2;9:1; FF 1:;2:;3:;4:;5:;6:;7:;8:;9:; C1 Institut des Sciences Exactes et Appliquées (ISEA)-EA 4243, Université de la Nouvelle-Calédonie, Nouméa Cedex, Nouvelle-Calédonie, France Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan Independant Researcher, Pergignan, France Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, USA Ecosystèmes Insulaires Océaniens (UMR EIO 241), University of French Polynesia, Faaa, French Polynesia C2 UNIV NOUVELLE CALEDONIE, FRANCE UNIV TOKUSHIMA BUNRI, JAPAN Independant Researcher, Pergignan, France UNIV OHIO STATE, USA UNIV POLYNESIE FRANCAISE, FRANCE UM EIO IN WOS Cotutelle UMR copubli-france copubli-univ-france copubli-int-hors-europe IF 2.488 TC 1 UR https://archimer.ifremer.fr/doc/00660/77195/78611.pdf LA English DT Article DE ;Liverwort;Porella viridissima;chemotype;pinguisane;sacculatane;ovarian cancer AB The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesquiterpenes are reported for the first time in liverwort. P. viridissima was found to belong to the chemotype III (pinguisane/sacculatane) and shared chemical similarities with P. navicularis. Perrotettianal A was isolated and has shown strong cytotoxicity against ovarian cancer. PY 2021 PD MAY SO Natural Product Research SN 1478-6419 PU Informa UK Limited VL 35 IS 12 UT 000483181900001 BP 2099 EP 2102 DI 10.1080/14786419.2019.1655022 ID 77195 ER EF