FN Archimer Export Format PT J TI Baseline Mapping of Schistosomiasis and Soil Transmitted Helminthiasis in the Northern and Eastern Health Regions of Gabon, Central Africa: Recommendations for Preventive Chemotherapy BT AF MINTSA NGUEMA, Rodrigue MAVOUNGOU, Jacques F. NGOU-MILAMA, Krystina Mengue Me MAMFOUMBI, Modeste Mabicka KOUMBA, Aubin A. LAMINE, Mariama Sani DIARRA, Abdoulaye ASSEKO, Ghislaine Nkone MOUROU, Jean R. AKOTET, Marielle K. Bouyou MONE, Helene MOUAHID, Gabriel ATSAME, Julienne AS 1:1,2,3;2:1;3:3,4;4:2;5:1;6:5;7:5,7;8:5;9:2;10:2;11:6;12:6;13:3; FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:;11:;12:;13:; C1 Natl Ctr Sci & Technol Res, Res Inst Trop Ecol, BP 13354, Libreville, Gabon. Univ Hlth Sci Libreville, Dept Parasitol Mycol, Fac Med, BP 4009, Libreville, Gabon. Control Program Parasit Dis, BP 2434, Libreville, Gabon. Natl Lab Publ Hlth, BP 10736, Libreville, Gabon. WHO, Country Off Gabon, BP 820, Libreville, Gabon. Univ Perpignan Via Domitia, Univ Montpellier, CNRS, IHPE,UM,IFREMER, F-66860 Perpignan, France. WHO Country Off Union Comores, POB 435, Moroni, Comoros. C2 CNRS LIBAN, GABON UNIV HLTH SCI LIBREVILLE, GABON CONTROL PROGRAM PARASIT DIS, GABON NPHL, GABON WHO, GABON UNIV PERPIGNAN, FRANCE WHO, COMOROS UM IHPE IN DOAJ IF 3.711 TC 12 UR https://archimer.ifremer.fr/doc/00660/77212/78691.pdf https://archimer.ifremer.fr/doc/00660/77212/78692.zip LA English DT Article DE ;schistosomiasis;soil-transmitted-helminthiasis;mapping;preventive chemotherapy;transmission control;Gabon;Central Africa AB In order to follow the Preventive Chemotherapy (PC) for the transmission control as recommended by WHO, Gabon initiated in 2014 the mapping of Schistosomiasis and Soil Transmitted Helminthiasis (STH). Here, we report the results of the Northern and Eastern health regions, representing a third of the land area and 12% of its total population. All nine departments of the two regions were surveyed and from each, five schools were examined with 50 schoolchildren per school. The parasitological examinations were realized using the filtration method for urine and the Kato-Katz technique for stool samples. Overall 2245 schoolchildren (1116 girls and 1129 boys), mean aged 11.28 +/- 0.04 years, were examined. Combined schistosomiasis and STH affected 1270 (56.6%) with variation between regions, departments, and schools. For schistosomiasis, prevalence were 1.7% across the two regions, with no significant difference (p > 0.05) between the Northern (1.5%) and the Eastern (1.9%). Schistosomiasis is mainly caused by Schistosoma haematobium with the exception of one respective case of S. mansoni and S. guineensis. STH are more common than schistosomiasis, with an overall prevalence of 56.1% significantly different between the Northern (58.1%) and Eastern (53.6%) regions (p = 0.034). Trichuris trichiura is the most abundant infection with a prevalence of 43.7% followed by Ascaris lumbricoides 35.6% and hookworms 1.4%. According to these results, an appropriate PC strategy is given. In particular, because of the low efficacy of a single recommended drug on T. trichiura and hookworms, it is important to include two drugs for the treatment of STH in Gabon, due to the high prevalence and intensities of Trichuris infections. PY 2018 PD DEC SO Tropical Medicine And Infectious Disease SN 2414-6366 PU Mdpi VL 3 IS 4 UT 000549494700015 DI 10.3390/tropicalmed3040119 ID 77212 ER EF