Marine Natural Occurring 2,5-Diketopiperazines: Isolation, Synthesis and Optical Properties
| Type | Article | ||||||||||||
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| Date | 2015-01 | ||||||||||||
| Language | English | ||||||||||||
| Author(s) | Laville Remi1, Thanh Binh Nguyen 1, Moriou Celine1, Petek Sylvain2, Debitus Cecile 2, Al-Mourabit Ali1 |
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| Affiliation(s) | 1 : CNRS, Inst Chim Subst Nat, Ctr Rech Gif Sur Yvette, F-91198 Gif Sur Yvette, France. 2 : Ctr Polynesie Francaise, IRD, UMR241, Papeete, France. |
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| Source | Heterocycles (0385-5414) (Pergamon-elsevier Science Ltd), 2015-01 , Vol. 90 , N. 2 , P. 1351-1366 | ||||||||||||
| DOI | 10.3987/COM-14-S(K)87 | ||||||||||||
| WOS© Times Cited | 9 | ||||||||||||
| Keyword(s) | Diketopiperazine, Sponge, Marine Metabolite, Circular Dichroism | ||||||||||||
| Abstract | Seven 2,5-diketopiperazines (DKPs) were isolated from the Fijian marine sponge Acanthella cavernosa. NMR and circular dichroism (CD) comparison with synthetic L-L DKPs allowed us to determine unambiguously the L-L absolute configuration of the natural DKPs. This work initiated the setting up of an optical properties database of natural DKPs, including specific rotation and CD. |
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