TY - JOUR T1 - Effects of nickel oxide nanoparticles on survival, reproduction, and oxidative stress biomarkers in the marine calanoid copepod Centropages ponticus under short-term exposure A1 - Djebbi,Emna A1 - Bonnet,Delphine A1 - Pringault,Olivier A1 - Tlili,Khawla A1 - Yahia,Mohamed Néjib Daly AD - Faculty of Sciences of Bizerte, Carthage University, 7021, Zarzouna, LR18ES41 (Tunis El Manar University), 1082, Tunis, Tunisia AD - Univ. Montpellier, CNRS, Ifremer, IRD, MARBEC, Montpellier, France AD - Aix Marseille Univ, Université de Toulon, CNRS, IRD, MIO UM 110, 13288, Marseille, France AD - LEBPAO, Faculty of Sciences of Tunis, University of Tunis, El Manar, FSB, Zarzouna, 7021, Bizerte, Tunisia AD - Department of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, PO Box 2713, Doha, Qatar UR - https://doi.org/10.1007/s11356-020-11781-1 DO - 10.1007/s11356-020-11781-1 KW - Metal oxide nanoparticle KW - Copepods KW - Acute toxicity test KW - Egg production KW - Egg hatching success KW - Antioxidant enzymes N2 - Excessive use of nickel oxide nanoparticles (NiO NPs) in various industrial and commercial products can lead to various negative effects in human and environmental health due to their possible discharge into the environment. Nerveless, information about their ecotoxicological effects on marine organisms are lacking. Copepods are good ecotoxicological models because of their high sensitivity to environmental stress and their key role in the marine food webs. In this study, 48 h acute tests were conducted on the marine planktonic copepod Centropages ponticus to assess lethal and sublethal toxicities of NiO NPs. The results revealed LC50 (48 h) of 4 mg/L for adult females. Aggregation and settling of NiO NPs were observed at concentrations ≥ 2 mg/L. Exposure to sublethal concentrations (≥ 0.02 mg/L for 48 h) had significant negative effects on reproductive success in C. ponticus. Egg production after 24 h and 48 h decreased by 32% and 46%, respectively at 0.02 mg/L and 70% and 82%, respectively, at 2 mg/L. Hatching success was reduced by 70% and 79% at 2 mg/L for eggs produced after 24 h and 48 h respectively. Antioxidant enzymatic activity increased significantly with NiO NP concentration and time, indicating that NiO NPs can cause oxidative stress in C. ponticus even under short-term exposure, while significant inhibition of acetylcholinesterase activity at 2 mg/L after 48 h suggests neurotoxic effects of NiO NPs. Y1 - 2021/05 PB - Springer Science and Business Media LLC JF - Environmental Science And Pollution Research SN - 0944-1344 VL - 28 IS - 17 SP - 21978 EP - 21990 ID - 78000 ER -