FN Archimer Export Format
PT J
TI Analysis across diverse fish species highlights no conserved transcriptome signature for proactive behaviour
BT 
AF Rey, Sonia
   Jin, Xingkun
   Damsgård, Børge
   BEGOUT, Marie-Laure
   Mackenzie, Simon
AS 1:1;2:1,2,3;3:4;4:5;5:1;
FF 1:;2:;3:;4:PDG-RBE-MARBEC-LAAAS;5:;
C1 Institute of Aquaculture, University of Stirling, Stirlingshire, FK9 4LA, UK
   Centre for Ecological and Evolutionary Synthesis (CEES), Department of Biosciences, University of Oslo, NO-0316, Oslo, Norway
   Institute of Marine Biology, College of Oceanography, Hohai University, Nanjing, 210098, China
   Faculty of Biosciences, Fisheries and Economics, UiT The Arctic University of Norway, 9037, Tromsø, Norway
   Ifremer, Place Gaby Coll, 17137 L’Houmeau, La Rochelle, France
C2 UNIV STIRLING, UK
   UNIV OSLO, NORWAY
   UNIV HOHAI, CHINA
   UNIV ARCTIC UIT NORWAY, NORWAY
   IFREMER, FRANCE
SI PALAVAS
SE PDG-RBE-MARBEC-LAAAS
UM MARBEC
IN WOS Ifremer UMR
   DOAJ
   copubli-europe
   copubli-int-hors-europe
   copubli-sud
IF 4.558
TC 5
UR https://archimer.ifremer.fr/doc/00668/78001/80227.pdf
   https://archimer.ifremer.fr/doc/00668/78001/80228.xlsx
   https://archimer.ifremer.fr/doc/00668/78001/80229.xls
   https://archimer.ifremer.fr/doc/00668/78001/80230.xlsx
   https://archimer.ifremer.fr/doc/00668/78001/80231.xls
   https://archimer.ifremer.fr/doc/00668/78001/80232.xlsx
   https://archimer.ifremer.fr/doc/00668/78001/80233.xls
   https://archimer.ifremer.fr/doc/00668/78001/80234.xls
   https://archimer.ifremer.fr/doc/00668/78001/80235.xls
   https://archimer.ifremer.fr/doc/00668/78001/80236.xlsx
   https://archimer.ifremer.fr/doc/00668/78001/80237.xls
   https://archimer.ifremer.fr/doc/00668/78001/80238.xls
   https://archimer.ifremer.fr/doc/00668/78001/80239.docx
LA English
DT Article
DE ;Proactive;Animal personality;RNA sequencing;Fish behaviour;Phenotype variation;Convergent evolution
AB Background Consistent individual differences in behaviour, known as animal personalities, have been demonstrated within and across species. In fish, studies applying an animal personality approach have been used to resolve variation in physiological and molecular data suggesting a linkage, genotype-phenotype, between behaviour and transcriptome regulation. In this study, using three fish species (zebrafish; Danio rerio, Atlantic salmon; Salmo salar and European sea bass; Dicentrarchus labrax), we firstly address whether personality-specific mRNA transcript abundances are transferrable across distantly-related fish species and secondly whether a proactive transcriptome signature is conserved across all three species. Results Previous zebrafish transcriptome data was used as a foundation to produce a curated list of mRNA transcripts related to animal personality across all three species. mRNA transcript copy numbers for selected gene targets show that differential mRNA transcript abundance in the brain appears to be partially conserved across species relative to personality type. Secondly, we performed RNA-Seq using whole brains from S. salar and D. labrax scoring positively for both behavioural and molecular assays for proactive behaviour. We further enriched this dataset by incorporating a zebrafish brain transcriptome dataset specific to the proactive phenotype. Our results indicate that cross-species molecular signatures related to proactive behaviour are functionally conserved where shared functional pathways suggest that evolutionary convergence may be more important than individual mRNAs. Conclusions Our data supports the proposition that highly polygenic clusters of genes, with small additive effects, likely support the underpinning molecular variation related to the animal personalities in the fish used in this study. The polygenic nature of the proactive brain transcriptome across all three species questions the existence of specific molecular signatures for proactive behaviour, at least at the granularity of specific regulatory gene modules, level of genes, gene networks and molecular functions. 
PY 2021
PD JAN
SO Bmc Genomics
SN 1471-2164
PU Springer Science and Business Media LLC
VL 22
IS 1
UT 000608287900006
DI 10.1186/s12864-020-07317-z
ID 78001
ER

EF