FN Archimer Export Format
PT J
TI Improving the Antioxidant Properties of Calophyllum inophyllum Seed Oil from French Polynesia: Development and Biological Applications of Resinous Ethanol-Soluble Extracts
BT 
AF Cassien, Mathieu
   Mercier, Anne
   Thétiot-Laurent, Sophie
   Culcasi, Marcel
   Ricquebourg, Emilie
   Asteian, Alice
   Herbette, Gaëtan
   Bianchini, Jean-Pierre
   Raharivelomanana, Phila
   Pietri, Sylvia
AS 1:1,2,3;2:1;3:1;4:1;5:1;6:1;7:4;8:2;9:2;10:1;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:;
C1 Campus Saint-Jérôme, CNRS, ICR, UMR 7273, SMBSO, Aix Marseille Université, 13397 Marseille, France
   IFREMER, ILM, IRD, EIO UMR 241, Université Polynésie Française, 98702 Faa’a Tahiti, French Polynesia
   Yelen Analytics, 13820 Ensuès–la-Redonne, France
   CNRS, Spectropole FSCM, Aix Marseille Université, 13397 Marseille, France
C2 UNIV AIX MARSEILLE, FRANCE
   UNIV POLYNESIE FRANCAISE, FRANCE
   YELEN ANALYTICS, FRANCE
   CNRS, FRANCE
UM EIO
IN WOS Cotutelle UMR
   DOAJ
   copubli-france
   copubli-univ-france
IF 7.675
TC 13
UR https://archimer.ifremer.fr/doc/00677/78918/81283.pdf
   https://archimer.ifremer.fr/doc/00677/78918/81284.pdf
LA English
DT Article
DE ;Calophyllum inophyllum L;Tamanu oil;ethanol-soluble resin extracts;lipophilic antioxidants;phenolics;pyranocoumarins;antimicrobial;anti-inflammatory;UV protection;EPR spin trapping
AB Tamanu oil from Calophyllum inophyllum L. has long been used in traditional medicine. Ethanol extraction was found the best strategy for recovering bioactive compounds from the resin part of Tamanu oil, yielding two neutral and acidic resins fractions with high phenolics, flavonoids and pyranocoumarins concentrations. A further cascade of LPLC/HPLC separations of neutral and acidic resin fractions allowed identifying fifteen metabolites, and among them, calanolide D and 12-oxocalanolide A (both in neutral fraction) were first identified from a natural source. All these extracts, subfractions and isolated metabolites demonstrated increased free radical scavenging, antioxidant, anti-inflammatory, antimicrobial and antimycobacterial activity compared to Tamanu oil and its de-resinated lipid phase. Overall, these results could promote resinous ethanol-soluble Tamanu oil extracts as a useful multifaceted and renewable medicinal resource 
PY 2021
PD FEB
SO Antioxidants
SN 2076-3921
PU MDPI AG
VL 10
IS 2
UT 000622045000001
DI 10.3390/antiox10020199
ID 78918
ER

EF