FN Archimer Export Format
PT J
TI Low oxygen levels can help to prevent the detrimental effect of acute warming on mitochondrial efficiency in fish
BT 
AF Thoral, Elisa
   Roussel, Damien
   Chinopoulos, Christos
   Teulier, Loïc
   Salin, Karine
AS 1:1;2:1;3:2;4:1;5:3;
FF 1:;2:;3:;4:;5:PDG-RBE-PFOM-LARN;
C1 Univ Lyon, Université Claude Bernard Lyon 1, CNRS, ENTPE, UMR 5023 LEHNA, F-69622, Villeurbanne, France
   Department of Medical Biochemistry, Semmelweis University, Budapest, 1094, Hungary
   Université de Brest, Ifremer, CNRS, IRD, Laboratory of Environmental Marine Sciences, Plouzané 29280, France
C2 UNIV LYON, FRANCE
   UNIV SEMMELWEIS, HUNGARY
   IFREMER, FRANCE
SI BREST
SE PDG-RBE-PFOM-LARN
UM LEMAR
IN WOS Ifremer UMR
   copubli-france
   copubli-europe
   copubli-univ-france
TC 12
UR https://archimer.ifremer.fr/doc/00679/79098/81571.pdf
   https://archimer.ifremer.fr/doc/00679/79098/81572.docx
LA English
DT Article
DE ;ATP/O ratio;mitochondrial respiratory capacities;dissolved oxygen;temperature
AB Aerobic metabolism of aquatic ectotherms is highly sensitive to fluctuating climates. Many mitochondrial traits exhibit phenotypic plasticity in response to acute variations in temperature and oxygen availability. These responses are critical for understanding the effects of environmental variations on aquatic ectotherms' performance. Using the European seabass, Dicentrarchus labrax, we determined the effects of acute warming and deoxygenation in vitro on mitochondrial respiratory capacities and mitochondrial efficiency to produce ATP (ATP/O ratio). We show that acute warming reduced ATP/O ratio but deoxygenation marginally raised ATP/O ratio, leading to a compensatory effect of low oxygen availability on mitochondrial ATP/O ratio at high temperature. The acute effect of warming and deoxygenation on mitochondrial efficiency might be related to the leak of protons across the mitochondrial inner membrane, as the mitochondrial respiration required to counteract the proton leak increased with warming and decreased with deoxygenation. Our study underlines the importance of integrating the combined effects of temperature and oxygen availability on mitochondrial metabolism. Predictions on decline in performance of aquatic ectotherms owing to climate change may not be accurate, since these predictions typically look at respiratory capacity and ignore efficiency of ATP production. 
PY 2021
PD FEB
SO Biology Letters
SN 1744-957X
PU The Royal Society
VL 17
IS 2
UT 000930276100001
DI 10.1098/rsbl.2020.0759
ID 79098
ER

EF