FN Archimer Export Format
PT J
TI Environmentally Driven Color Variation in the Pearl Oyster Pinctada margaritifera var. cumingii (Linnaeus, 1758) Is Associated With Differential Methylation of CpGs in Pigment- and Biomineralization-Related Genes
BT 
AF Stenger, Pierre-Louis
   Ky, Chin-Long
   Reisser, Celine
   Cosseau, Céline
   Grunau, Christoph
   MEGE, Mickael
   Planes, Serge
   Vidal-Dupiol, Jeremie
AS 1:1,2;2:1,2;3:1,3;4:4;5:4;6:1,5;7:6;8:2;
FF 1:PDG-RBE-RMPF;2:PDG-RBE-IHPE;3:PDG-RBE-MARBEC;4:;5:;6:PDG-RBE-SGMM-LGPMM;7:;8:PDG-RBE-IHPE;
C1 IFREMER, UMR 241 Écosystèmes Insulaires Océaniens, Labex Corail, Centre du Pacifique, Tahiti, French Polynesia
   IHPE, Université de Montpellier, CNRS, IFREMER, Université de Perpignan Via Domitia, Montpellier, France
   MARBEC, Université de Montpellier, CNRS, IFREMER, IRD, Montpellier, France
   IHPE, Université de Montpellier, CNRS, IFREMER, Université de Perpignan Via Domitia, Perpignan, France
   IFREMER, PDG-RBE-SGMM-LGPMM, La Tremblade, France
   EPHE-UPVD-CNRS, USR 3278 CRIOBE, Labex Corail, PSL Research University, Université de Perpignan, Perpignan, France
C2 IFREMER, FRANCE
   IFREMER, FRANCE
   IFREMER, FRANCE
   UNIV MONTPELLIER, FRANCE
   IFREMER, FRANCE
   UNIV PERPIGNAN, FRANCE
SI TAHITI
   MONTPELLIER
   LA TREMBLADE
SE PDG-RBE-RMPF
   PDG-RBE-IHPE
   PDG-RBE-MARBEC
   PDG-RBE-SGMM-LGPMM
UM MARBEC
   IHPE
   EIO
IN WOS Ifremer UPR
   WOS Ifremer UMR
   WOS Cotutelle UMR
   DOAJ
   copubli-france
   copubli-univ-france
IF 4.772
TC 5
UR https://archimer.ifremer.fr/doc/00685/79667/82436.pdf
   https://archimer.ifremer.fr/doc/00685/79667/82437.xlsx
   https://archimer.ifremer.fr/doc/00685/79667/82438.xlsx
   https://archimer.ifremer.fr/doc/00685/79667/82439.xlsx
   https://archimer.ifremer.fr/doc/00685/79667/82440.pptx
   https://archimer.ifremer.fr/doc/00685/79667/82441.zip
LA English
DT Article
DE ;pearl oyster;environmental pressure;depth;color change;pigmentation;DNA methylation;methylome characterization
AB Today, it is common knowledge that environmental factors can change the color of many animals. Studies have shown that the molecular mechanisms underlying such modifications could involve epigenetic factors. Since 2013, the pearl oyster Pinctada margaritifera var. cumingii has become a biological model for questions on color expression and variation in Mollusca. A previous study reported color plasticity in response to water depth variation, specifically a general darkening of the nacre color at greater depth. However, the molecular mechanisms behind this plasticity are still unknown. In this paper, we investigate the possible implication of epigenetic factors controlling shell color variation through a depth variation experiment associated with a DNA methylation study performed at the whole genome level with a constant genetic background. Our results revealed six genes presenting differentially methylated CpGs in response to the environmental change, among which four are linked to pigmentation processes or regulations (GART, ABCC1, MAPKAP1, and GRL101), especially those leading to darker phenotypes. Interestingly, the genes perlucin and MGAT1, both involved in the biomineralization process (deposition of aragonite and calcite crystals), also showed differential methylation, suggesting that a possible difference in the physical/spatial organization of the crystals could cause darkening (iridescence or transparency modification of the biomineral). These findings are of great interest for the pearl production industry, since wholly black pearls and their opposite, the palest pearls, command a higher value on several markets. They also open the route of epigenetic improvement as a new means for pearl production improvement. 
PY 2021
PD MAR
SO Frontiers In Genetics
SN 1664-8021
PU Frontiers Media SA
VL 12
UT 000635978000001
DI 10.3389/fgene.2021.630290
ID 79667
ER

EF