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Cebollada Rica, Paula Cecarini, Valentina Cecconi, Francesco Cechowska-Pasko, Marzanna Cenci, Simone Ceperuelo-Mallafré, Victòria Cerqueira, João J. Cerutti, Janete M. Cervia, Davide Cetintas, Vildan Bozok Cetrullo, Silvia Chae, Han-Jung Chagin, Andrei S. Chai, Chee-Yin Chakrabarti, Gopal Chakrabarti, Oishee Chakraborty, Tapas Chakraborty, Trinad Chami, Mounia Chamilos, Georgios Chan, David W. Chan, Edmond Y. W. Chan, Edward D. Chan, H.Y. Edwin Chan, Helen H. Chan, Hung Chan, Matthew T.V. Chan, Yau Sang Chandra, Partha K. Chang, Chih-Peng Chang, Chunmei Chang, Hao-Chun Chang, Kai Chao, Jie Chapman, Tracey Charlet-Berguerand, Nicolas Chatterjee, Samrat Chaube, Shail K. Chaudhary, Anu Chauhan, Santosh Chaum, Edward Checler, Frédéric Cheetham, Michael E. Chen, Chang-Shi Chen, Guang-Chao Chen, Jian-Fu Chen, Liam L. Chen, Leilei Chen, Lin Chen, Mingliang Chen, Mu-Kuan Chen, Ning Chen, Quan Chen, Ruey-Hwa Chen, Shi Chen, Wei Chen, Weiqiang Chen, Xin-Ming Chen, Xiong-Wen Chen, Xu Chen, Yan Chen, Ye-Guang Chen, Yingyu Chen, Yongqiang Chen, Yu-Jen Chen, Yue-Qin Chen, Zhefan Stephen Chen, Zhi Chen, Zhi-Hua Chen, Zhijian J. Chen, Zhixiang Cheng, Hanhua Cheng, Jun Cheng, Shi-Yuan Cheng, Wei Cheng, Xiaodong Cheng, Xiu-Tang Cheng, Yiyun Cheng, Zhiyong Chen, Zhong Cheong, Heesun Cheong, Jit Kong Chernyak, Boris V. Cherry, Sara Cheung, Chi Fai Randy Cheung, Chun Hei Antonio Cheung, King-Ho Chevet, Eric Chi, Richard J. Chiang, Alan Kwok Shing Chiaradonna, Ferdinando Chiarelli, Roberto Chiariello, Mario Chica, Nathalia Chiocca, Susanna Chiong, Mario Chiou, Shih-Hwa Chiramel, Abhilash I. Chiurchiù, Valerio Cho, Dong-Hyung Choe, Seong-Kyu Choi, Augustine M.K. Choi, Mary E. Choudhury, Kamalika Roy Chow, Norman S. Chu, Charleen T. Chua, Jason P. 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Cybulsky, Andrey V. Czaja, Mark J. Czuczwar, Stanislaw J. D’Adamo, Stefania D’Amelio, Marcello D’Arcangelo, Daniela D’Lugos, Andrew C. D’Orazi, Gabriella da Silva, James A. Dafsari, Hormos Salimi Dagda, Ruben K. Dagdas, Yasin Daglia, Maria Dai, Xiaoxia Dai, Yun Dai, Yuyuan Dal Col, Jessica Dalhaimer, Paul Dalla Valle, Luisa Dallenga, Tobias Dalmasso, Guillaume Damme, Markus Dando, Ilaria Dantuma, Nico P. Darling, April L. Das, Hiranmoy Dasarathy, Srinivasan Dasari, Santosh K. Dash, Srikanta Daumke, Oliver Dauphinee, Adrian N. Davies, Jeffrey S. Dávila, Valeria A. Davis, Roger J. Davis, Tanja Dayalan Naidu, Sharadha De Amicis, Francesca De Bosscher, Karolien De Felice, Francesca De Franceschi, Lucia De Leonibus, Chiara de Mattos Barbosa, Mayara G. De Meyer, Guido R.Y. De Milito, Angelo De Nunzio, Cosimo De Palma, Clara De Santi, Mauro De Virgilio, Claudio De Zio, Daniela Debnath, Jayanta DeBosch, Brian J. Decuypere, Jean-Paul Deehan, Mark A. 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Engedal, Nikolai Engelbrecht, Anna-Mart Engelsen, Agnete S.T. Enserink, Jorrit M. Escalante, Ricardo Esclatine, Audrey Escobar-Henriques, Mafalda Eskelinen, Eeva-Liisa Espert, Lucile Eusebio, Makandjou-Ola Fabrias, Gemma Fabrizi, Cinzia Facchiano, Antonio Facchiano, Francesco Fadeel, Bengt Fader, Claudio Faesen, Alex C. Fairlie, W. Douglas Falcó, Alberto Falkenburger, Bjorn H. Fan, Daping Fan, Jie Fan, Yanbo Fang, Evandro F. Fang, Yanshan Fang, Yognqi Fanto, Manolis Farfel-Becker, Tamar Faure, Mathias Fazeli, Gholamreza Fedele, Anthony O. Feldman, Arthur M. Feng, Du Feng, Jiachun Feng, Lifeng Feng, Yibin Feng, Yuchen Feng, Wei Fenz Araujo, Thais Ferguson, Thomas A. Fernández, Álvaro F. Fernandez-Checa, Jose C. Fernández-Veledo, Sonia Fernie, Alisdair R. Ferrante, Anthony W. Ferraresi, Alessandra Ferrari, Merari F. Ferreira, Julio C.B. 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Gao, Feng Gao, Hui Gao, Minghui Gao, Ping Gao, Shou-Jiang Gao, Wentao Gao, Xiaobo Garcera, Ana Garcia, Maria Noé Garcia, Verónica E. García-Del Portillo, Francisco Garcia-Escudero, Vega Garcia-Garcia, Aracely Garcia-Macia, Marina García-Moreno, Diana Garcia-Ruiz, Carmen García-Sanz, Patricia Garg, Abhishek D. Gargini, Ricardo Garofalo, Tina Garry, Robert F. Gassen, Nils C. Gatica, Damian Ge, Liang Ge, Wanzhong Geiss-Friedlander, Ruth Gelfi, Cecilia Genschik, Pascal Gentle, Ian E. Gerbino, Valeria Gerhardt, Christoph Germain, Kyla Germain, Marc Gewirtz, David A. Ghasemipour Afshar, Elham Ghavami, Saeid Ghigo, Alessandra Ghosh, Manosij Giamas, Georgios Giampietri, Claudia Giatromanolaki, Alexandra Gibson, Gary E. Gibson, Spencer B. Ginet, Vanessa Giniger, Edward Giorgi, Carlotta Girao, Henrique Girardin, Stephen E. 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Guda, Kishore Guerra, Flora Guerri, Consuelo Guha, Prasun Guillén, Carlos Gujar, Shashi Gukovskaya, Anna Gukovsky, Ilya Gunst, Jan Günther, Andreas Guntur, Anyonya R. Guo, Chuanyong Guo, Chun Guo, Hongqing Guo, Lian-Wang Guo, Ming Gupta, Pawan Gupta, Shashi Kumar Gupta, Swapnil Gupta, Veer Bala Gupta, Vivek Gustafsson, Asa B. Gutterman, David D. H.B., Ranjitha Haapasalo, Annakaisa Haber, James E. Hać, Aleksandra Hadano, Shinji Hafrén, Anders J. Haidar, Mansour Hall, Belinda S. Halldén, Gunnel Hamacher-Brady, Anne Hamann, Andrea Hamasaki, Maho Han, Weidong Hansen, Malene Hanson, Phyllis I.  Hao, Zijian Harada, Masaru Harhaji-Trajkovic, Ljubica Hariharan, Nirmala Haroon, Nigil Harris, James Hasegawa, Takafumi Hasima Nagoor, Noor Haspel, Jeffrey A. Haucke, Volker Hawkins, Wayne D. Hay, Bruce A. Haynes, Cole M. Hayrabedyan, Soren B. Hays, Thomas S. He, Congcong He, Qin He, Rong-Rong He, You-Wen He, Yu-Ying Heakal, Yasser Heberle, Alexander M. Hejtmancik, J. 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Kanamori, Hiromitsu Kanasaki, Keizo Kang, Chanhee Kang, Rui Kang, Sang Sun Kaniyappan, Senthilvelrajan Kanki, Tomotake Kanneganti, Thirumala-Devi Kanthasamy, Anumantha G. Kanthasamy, Arthi Kantorow, Marc Kapuy, Orsolya Karamouzis, Michalis V. Karim, Md. Razaul Karmakar, Parimal Katare, Rajesh G. Kato, Masaru Kaufmann, Stefan H.E. Kauppinen, Anu Kaushal, Gur P. Kaushik, Susmita Kawasaki, Kiyoshi Kazan, Kemal Ke, Po-Yuan Keating, Damien J. Keber, Ursula Kehrl, John H. Keller, Kate E. Keller, Christian W. Kemper, Jongsook Kim Kenific, Candia M. Kepp, Oliver Kermorgant, Stephanie Kern, Andreas Ketteler, Robin Keulers, Tom G. Khalfin, Boris Khalil, Hany Khambu, Bilon Khan, Shahid Y. Khandelwal, Vinoth Kumar Megraj Khandia, Rekha Kho, Widuri Khobrekar, Noopur V. Khuansuwan, Sataree Khundadze, Mukhran Killackey, Samuel A. Kim, Dasol Kim, Deok Ryong Kim, Do-Hyung Kim, Dong-Eun Kim, Eun Young Kim, Eun-Kyoung Kim, Hak-Rim Kim, Hee-Sik Kim, Jeong Hun Kim, Jin Kyung Kim, Jin-Hoi Kim, Joungmok Kim, Ju Hwan Kim, Keun Il Kim, Peter K. Kim, Seong-Jun Kimball, Scot R. Kimchi, Adi Kimmelman, Alec C. Kimura, Tomonori King, Matthew A. Kinghorn, Kerri J. Kinsey, Conan G. Kirkin, Vladimir Kirshenbaum, Lorrie A. Kiselev, Sergey L. Kishi, Shuji Kitamoto, Katsuhiko Kitaoka, Yasushi Kitazato, Kaio Kitsis, Richard N. Kittler, Josef T. Kjaerulff, Ole Klein, Peter S. Klopstock, Thomas Klucken, Jochen Knævelsrud, Helene Knorr, Roland L. Ko, Ben C.B. Ko, Fred Ko, Jiunn-Liang Kobayashi, Hotaka Kobayashi, Satoru Koch, Ina Koch, Jan C. Koenig, Ulrich Kögel, Donat Koh, Young Ho Koike, Masato Kohlwein, Sepp D. Kocaturk, Nur M. Komatsu, Masaaki König, Jeannette Kono, Toru Kopp, Benjamin T. Korcsmaros, Tamas Korkmaz, Gözde Korolchuk, Viktor I. Korsnes, Mónica Suárez Koskela, Ali Kota, Janaiah Kotake, Yaichiro Kotler, Monica L. Kou, Yanjun Koukourakis, Michael I. Koustas, Evangelos Kovacs, Attila L. Kovács, Tibor Koya, Daisuke Kozako, Tomohiro Kraft, Claudine Krainc, Dimitri Krämer, Helmut Krasnodembskaya, Anna D. Kretz-Remy, Carole Kroemer, Guido Ktistakis, Nicholas T. Kuchitsu, Kazuyuki Kuenen, Sabine Kuerschner, Lars Kukar, Thomas Kumar, Ajay Kumar, Ashok Kumar, Deepak Kumar, Dhiraj Kumar, Sharad Kume, Shinji Kumsta, Caroline Kundu, Chanakya N. Kundu, Mondira Kunnumakkara, Ajaikumar B. Kurgan, Lukasz Kutateladze, Tatiana G. Kutlu, Ozlem Kwak, SeongAe Kwon, Ho Jeong Kwon, Taeg Kyu Kwon, Yong Tae Kyrmizi, Irene La Spada, Albert Labonté, Patrick Ladoire, Sylvain Laface, Ilaria Lafont, Frank Lagace, Diane C. Lahiri, Vikramjit Lai, Zhibing Laird, Angela S. Lakkaraju, Aparna Lamark, Trond Lan, Sheng-Hui Landajuela, Ane Lane, Darius J. R. Lane, Jon D. Lang, Charles H. Lange, Carsten Langel, Ülo Langer, Rupert Lapaquette, Pierre Laporte, Jocelyn LaRusso, Nicholas F. Lastres-Becker, Isabel Lau, Wilson Chun Yu Laurie, Gordon W. Lavandero, Sergio Law, Betty Yuen Kwan Law, Helen Ka-wai Layfield, Rob Le, Weidong Le Stunff, Herve Leary, Alexandre Y. Lebrun, Jean-Jacques Leck, Lionel Y.W. Leduc-Gaudet, Jean-Philippe Lee, Changwook Lee, Chung-Pei Lee, Da-Hye Lee, Edward B. Lee, Erinna F. Lee, Gyun Min Lee, He-Jin Lee, Heung Kyu Lee, Jae Man Lee, Jason S. Lee, Jin-A Lee, Joo-Yong Lee, Jun Hee Lee, Michael Lee, Min Goo Lee, Min Jae Lee, Myung-Shik Lee, Sang Yoon Lee, Seung-Jae Lee, Stella Y. Lee, Sung Bae Lee, Won Hee Lee, Ying-Ray Lee, Yong-ho Lee, Youngil Lefebvre, Christophe Legouis, Renaud Lei, Yu L. Lei, Yuchen Leikin, Sergey Leitinger, Gerd Lemus, Leticia Leng, Shuilong Lenoir, Olivia Lenz, Guido Lenz, Heinz Josef Lenzi, Paola León, Yolanda Leopoldino, Andréia M. Leschczyk, Christoph Leskelä, Stina Letellier, Elisabeth Leung, Chi-Ting Leung, Po Sing Leventhal, Jeremy S. Levine, Beth Lewis, Patrick A. Ley, Klaus Li, Bin Li, Da-Qiang Li, Jianming Li, Jing Li, Jiong Li, Ke Li, Liwu Li, Mei Li, Min Li, Min Li, Ming Li, Mingchuan Li, Pin-Lan Li, Ming-Qing Li, Qing Li, Sheng Li, Tiangang Li, Wei Li, Wenming Li, Xue Li, Yi-Ping Li, Yuan Li, Zhiqiang Li, Zhiyong Li, Zhiyuan Lian, Jiqin Liang, Chengyu Liang, Qiangrong Liang, Weicheng Liang, Yongheng Liang, YongTian Liao, Guanghong Liao, Lujian Liao, Mingzhi Liao, Yung-Feng Librizzi, Mariangela Lie, Pearl P. Y. Lilly, Mary A. Lim, Hyunjung J. Lima, Thania R.R. Limana, Federica Lin, Chao Lin, Chih-Wen Lin, Dar-Shong Lin, Fu-Cheng Lin, Jiandie D. Lin, Kurt M. Lin, Kwang-Huei Lin, Liang-Tzung Lin, Pei-Hui Lin, Qiong Lin, Shaofeng Lin, Su-Ju Lin, Wenyu Lin, Xueying Lin, Yao-Xin Lin, Yee-Shin Linden, Rafael Lindner, Paula Ling, Shuo-Chien Lingor, Paul Linnemann, Amelia K. Liou, Yih-Cherng Lipinski, Marta M. Lipovšek, Saška Lira, Vitor A. Lisiak, Natalia Liton, Paloma B. Liu, Chao Liu, Ching-Hsuan Liu, Chun-Feng Liu, Cui Hua Liu, Fang Liu, Hao Liu, Hsiao-Sheng Liu, Hua-feng Liu, Huifang Liu, Jia Liu, Jing Liu, Julia Liu, Leyuan Liu, Longhua Liu, Meilian Liu, Qin Liu, Wei Liu, Wende Liu, Xiao-Hong Liu, Xiaodong Liu, Xingguo Liu, Xu Liu, Xuedong Liu, Yanfen Liu, Yang Liu, Yang Liu, Yueyang Liu, Yule Livingston, J. Andrew Lizard, Gerard Lizcano, Jose M. Ljubojevic-Holzer, Senka LLeonart, Matilde E. Llobet-Navàs, David Llorente, Alicia Lo, Chih Hung Lobato-Márquez, Damián Long, Qi Long, Yun Chau Loos, Ben Loos, Julia A. López, Manuela G. López-Doménech, Guillermo López-Guerrero, José Antonio López-Jiménez, Ana T. López-Pérez, Óscar López-Valero, Israel Lorenowicz, Magdalena J. Lorente, Mar Lorincz, Peter Lossi, Laura Lotersztajn, Sophie Lovat, Penny E. Lovell, Jonathan F. Lovy, Alenka Lőw, Péter Lu, Guang Lu, Haocheng Lu, Jia-Hong Lu, Jin-Jian Lu, Mengji Lu, Shuyan Luciani, Alessandro Lucocq, John M. Ludovico, Paula Luftig, Micah A. Luhr, Morten Luis-Ravelo, Diego Lum, Julian J. Luna-Dulcey, Liany Lund, Anders H. Lund, Viktor K. Lünemann, Jan D. Lüningschrör, Patrick Luo, Honglin Luo, Rongcan Luo, Shouqing Luo, Zhi Luparello, Claudio Lüscher, Bernhard Luu, Luan Lyakhovich, Alex Lyamzaev, Konstantin G. Lystad, Alf Håkon Lytvynchuk, Lyubomyr Ma, Alvin C. Ma, Changle Ma, Mengxiao Ma, Ning-Fang Ma, Quan-Hong Ma, Xinliang Ma, Yueyun Ma, Zhenyi MacDougald, Ormond A. Macian, Fernando MacIntosh, Gustavo C. MacKeigan, Jeffrey P. Macleod, Kay F. Maday, Sandra Madeo, Frank Madesh, Muniswamy Madl, Tobias Madrigal-Matute, Julio Maeda, Akiko Maejima, Yasuhiro Magarinos, Marta Mahavadi, Poornima Maiani, Emiliano Maiese, Kenneth Maiti, Panchanan Maiuri, Maria Chiara Majello, Barbara Major, Michael B. Makareeva, Elena Malik, Fayaz Mallilankaraman, Karthik Malorni, Walter Maloyan, Alina Mammadova, Najiba Man, Gene Chi Wai Manai, Federico Mancias, Joseph D. Mandelkow, Eva-Maria Mandell, Michael A. Manfredi, Angelo A. Manjili, Masoud H. Manjithaya, Ravi Manque, Patricio Manshian, Bella B. Manzano, Raquel Manzoni, Claudia Mao, Kai Marchese, Cinzia Marchetti, Sandrine Marconi, Anna Maria Marcucci, Fabrizio Mardente, Stefania Mareninova, Olga A. Margeta, Marta Mari, Muriel Marinelli, Sara Marinelli, Oliviero Mariño, Guillermo Mariotto, Sofia Marshall, Richard S. Marten, Mark R. Martens, Sascha Martin, Alexandre P.J. Martin, Katie R. Martin, Sara Martin, Shaun Martín-Segura, Adrián Martín-Acebes, Miguel A. Martin-Burriel, Inmaculada Martin-Rincon, Marcos Martin-Sanz, Paloma Martina, José A. Martinet, Wim Martinez, Aitor Martinez, Ana Martinez, Jennifer Martinez Velazquez, Moises Martinez-Lopez, Nuria Martinez-Vicente, Marta Martins, Daniel O. Martins, Joilson O. Martins, Waleska K. Martins-Marques, Tania Marzetti, Emanuele Masaldan, Shashank Masclaux-Daubresse, Celine Mashek, Douglas G. Massa, Valentina Massieu, Lourdes Masson, Glenn R. Masuelli, Laura Masyuk, Anatoliy I. Masyuk, Tetyana V. Matarrese, Paola Matheu, Ander Matoba, Satoaki Matsuzaki, Sachiko Mattar, Pamela Matte, Alessandro Mattoscio, Domenico Mauriz, José L. Mauthe, Mario Mauvezin, Caroline Maverakis, Emanual Maycotte, Paola Mayer, Johanna Mazzoccoli, Gianluigi Mazzoni, Cristina Mazzulli, Joseph R. McCarty, Nami McDonald, Christine McGill, Mitchell R. McKenna, Sharon L. McLaughlin, BethAnn McLoughlin, Fionn McNiven, Mark A. McWilliams, Thomas G. Mechta-Grigoriou, Fatima Medeiros, Tania Catarina Medina, Diego L. Megeney, Lynn A. Megyeri, Klara Mehrpour, Maryam Mehta, Jawahar L. Meijer, Alfred J. Meijer, Annemarie H. Mejlvang, Jakob Meléndez, Alicia Melk, Annette Memisoglu, Gonen Mendes, Alexandrina F. Meng, Delong Meng, Fei Meng, Tian Menna-Barreto, Rubem Menon, Manoj B. Mercer, Carol Mercier, Anne E. Mergny, Jean-Louis Merighi, Adalberto Merkley, Seth D. Merla, Giuseppe Meske, Volker Mestre, Ana Cecilia Metur, Shree Padma Meyer, Christian Meyer, Hemmo Mi, Wenyi Mialet-Perez, Jeanne Miao, Junying Micale, Lucia Miki, Yasuo Milan, Enrico Milczarek, Małgorzata Miller, Dana L. Miller, Samuel I. Miller, Silke Millward, Steven W. Milosevic, Ira Minina, Elena A. Mirzaei, Hamed Mirzaei, Hamid Reza Mirzaei, Mehdi Mishra, Amit Mishra, Nandita Mishra, Paras Kumar Misirkic Marjanovic, Maja Misasi, Roberta Misra, Amit Misso, Gabriella Mitchell, Claire Mitou, Geraldine Miura, Tetsuji Miyamoto, Shigeki Miyazaki, Makoto Miyazaki, Mitsunori Miyazaki, Taiga Miyazawa, Keisuke Mizushima, Noboru Mogensen, Trine H. Mograbi, Baharia Mohammadinejad, Reza Mohamud, Yasir Mohanty, Abhishek Mohapatra, Sipra Möhlmann, Torsten Mohmmed, Asif Moles, Anna Moley, Kelle H. Molinari, Maurizio Mollace, Vincenzo Møller, Andreas Buch Mollereau, Bertrand Mollinedo, Faustino Montagna, Costanza Monteiro, Mervyn J. Montella, Andrea Montes, L. Ruth Montico, Barbara Mony, Vinod K. Monzio Compagnoni, Giacomo Moore, Michael N. Moosavi, Mohammad A. Mora, Ana L. Mora, Marina Morales-Alamo, David Moratalla, Rosario Moreira, Paula I. Morelli, Elena Moreno, Sandra Moreno-Blas, Daniel Moresi, Viviana Morga, Benjamin Morgan, Alwena H. Morin, Fabrice Morishita, Hideaki Moritz, Orson L. Moriyama, Mariko Moriyasu, Yuji Morleo, Manuela Morselli, Eugenia Moruno-Manchon, Jose F. Moscat, Jorge Mostowy, Serge Motori, Elisa Moura, Andrea Felinto Moustaid-Moussa, Naima Mrakovcic, Maria Muciño-Hernández, Gabriel Mukherjee, Anupam Mukhopadhyay, Subhadip Mulcahy Levy, Jean M. Mulero, Victoriano Muller, Sylviane Münch, Christian Munjal, Ashok Munoz-Canoves, Pura Muñoz-Galdeano, Teresa Münz, Christian Murakawa, Tomokazu Muratori, Claudia Murphy, Brona M. Murphy, J. Patrick Murthy, Aditya Myöhänen, Timo T. Mysorekar, Indira U. Mytych, Jennifer Nabavi, Seyed Mohammad Nabissi, Massimo Nagy, Péter Nah, Jihoon Nahimana, Aimable Nakagawa, Ichiro Nakamura, Ken Nakatogawa, Hitoshi Nandi, Shyam S. Nanjundan, Meera Nanni, Monica Napolitano, Gennaro Nardacci, Roberta Narita, Masashi Nassif, Melissa Nathan, Ilana Natsumeda, Manabu Naude, Ryno J. Naumann, Christin Naveiras, Olaia Navid, Fatemeh Nawrocki, Steffan T. Nazarko, Taras Y. Nazio, Francesca Negoita, Florentina Neill, Thomas Neisch, Amanda L. Neri, Luca M. Netea, Mihai G. Neubert, Patrick Neufeld, Thomas P. Neumann, Dietbert Neutzner, Albert Newton, Phillip T. Ney, Paul A. Nezis, Ioannis P. Ng, Charlene C.W. Ng, Tzi Bun Nguyen, Hang T. T. Nguyen, Long T. Ni, Hong-Min Ní Cheallaigh, Clíona Ni, Zhenhong Nicolao, M. Celeste Nicoli, Francesco Nieto-Diaz, Manuel Nilsson, Per Ning, Shunbin Niranjan, Rituraj Nishimune, Hiroshi Niso-Santano, Mireia Nixon, Ralph A. Nobili, Annalisa Nobrega, Clevio Noda, Takeshi Nogueira-Recalde, Uxía Nolan, Trevor M. Nombela, Ivan Novak, Ivana Novoa, Beatriz Nozawa, Takashi Nukina, Nobuyuki Nussbaum-Krammer, Carmen Nylandsted, Jesper O’Donovan, Tracey R. O’Leary, Seónadh M. O’Rourke, Eyleen J. O’Sullivan, Mary P. O’Sullivan, Timothy E. Oddo, Salvatore Oehme, Ina Ogawa, Michinaga Ogier-Denis, Eric Ogmundsdottir, Margret H. Ogretmen, Besim Oh, Goo Taeg Oh, Seon-Hee Oh, Young J. Ohama, Takashi Ohashi, Yohei Ohmuraya, Masaki Oikonomou, Vasileios Ojha, Rani Okamoto, Koji Okazawa, Hitoshi Oku, Masahide Oliván, Sara Oliveira, Jorge M. A. Ollmann, Michael Olzmann, James A. Omari, Shakib Omary, M. Bishr Önal, Gizem Ondrej, Martin Ong, Sang-Bing Ong, Sang-Ging Onnis, Anna Orellana, Juan A. Orellana-Muñoz, Sara Ortega-Villaizan, Maria Del Mar Ortiz-Gonzalez, Xilma R. Ortona, Elena Osiewacz, Heinz D. Osman, Abdel-Hamid K. Osta, Rosario Otegui, Marisa S. Otsu, Kinya Ott, Christiane Ottobrini, Luisa Ou, Jing-hsiung James Outeiro, Tiago F. Oynebraten, Inger Ozturk, Melek Pagès, Gilles Pahari, Susanta Pajares, Marta Pajvani, Utpal B. Pal, Rituraj Paladino, Simona Pallet, Nicolas Palmieri, Michela Palmisano, Giuseppe Palumbo, Camilla Pampaloni, Francesco Pan, Lifeng Pan, Qingjun Pan, Wenliang Pan, Xin Panasyuk, Ganna Pandey, Rahul Pandey, Udai B. Pandya, Vrajesh Paneni, Francesco Pang, Shirley Y. Panzarini, Elisa Papademetrio, Daniela L. Papaleo, Elena Papinski, Daniel Papp, Diana Park, Eun Chan Park, Hwan Tae Park, Ji-Man Park, Jong-In Park, Joon Tae Park, Junsoo Park, Sang Chul Park, Sang-Youel Parola, Abraham H. Parys, Jan B. Pasquier, Adrien Pasquier, Benoit Passos, João F. Pastore, Nunzia Patel, Hemal H. Patschan, Daniel Pattingre, Sophie Pedraza-Alva, Gustavo Pedraza-Chaverri, Jose Pedrozo, Zully Pei, Gang Pei, Jianming Peled-Zehavi, Hadas Pellegrini, Joaquín M. Pelletier, Joffrey Peñalva, Miguel A. Peng, Di Peng, Ying Penna, Fabio Pennuto, Maria Pentimalli, Francesca Pereira, Cláudia MF Pereira, Gustavo J.S. Pereira, Lilian C. Pereira de Almeida, Luis Perera, Nirma D. Pérez-Lara, Ángel Perez-Oliva, Ana B. Pérez-Pérez, María Esther Periyasamy, Palsamy Perl, Andras Perrotta, Cristiana Perrotta, Ida Pestell, Richard G. Petersen, Morten Petrache, Irina Petrovski, Goran Pfirrmann, Thorsten Pfister, Astrid S. Philips, Jennifer A. Pi, Huifeng Picca, Anna Pickrell, Alicia M. Picot, Sandy Pierantoni, Giovanna M. Pierdominici, Marina Pierre, Philippe Pierrefite-Carle, Valérie Pierzynowska, Karolina Pietrocola, Federico Pietruczuk, Miroslawa Pignata, Claudio Pimentel-Muiños, Felipe X. Pinar, Mario Pinheiro, Roberta O. Pinkas-Kramarski, Ronit Pinton, Paolo Pircs, Karolina Piya, Sujan Pizzo, Paola Plantinga, Theo S. Platta, Harald W. Plaza-Zabala, Ainhoa Plomann, Markus Plotnikov, Egor Y. Plun-Favreau, Helene Pluta, Ryszard Pocock, Roger Pöggeler, Stefanie Pohl, Christian Poirot, Marc Poletti, Angelo Ponpuak, Marisa Popelka, Hana Popova, Blagovesta Porta, Helena Porte Alcon, Soledad Portilla-Fernandez, Eliana Post, Martin Potts, Malia B. Poulton, Joanna Powers, Ted Prahlad, Veena Prajsnar, Tomasz K. Praticò, Domenico Prencipe, Rosaria Priault, Muriel Proikas-Cezanne, Tassula Promponas, Vasilis J. Proud, Christopher G. Puertollano, Rosa Puglielli, Luigi Pulinilkunnil, Thomas Puri, Deepika Puri, Rajat Puyal, Julien Qi, Xiaopeng Qi, Yongmei Qian, Wenbin Qiang, Lei Qiu, Yu Quadrilatero, Joe Quarleri, Jorge Raben, Nina Rabinowich, Hannah Ragona, Debora Ragusa, Michael J. Rahimi, Nader Rahmati, Marveh Raia, Valeria Raimundo, Nuno Rajasekaran, Namakkal-Soorappan Ramachandra Rao, Sriganesh Rami, Abdelhaq Ramírez-Pardo, Ignacio Ramsden, David B. Randow, Felix Rangarajan, Pundi N. Ranieri, Danilo Rao, Hai Rao, Lang Rao, Rekha Rathore, Sumit Ratnayaka, J. Arjuna Ratovitski, Edward A. Ravanan, Palaniyandi Ravegnini, Gloria Ray, Swapan K. Razani, Babak Rebecca, Vito Reggiori, Fulvio Régnier-Vigouroux, Anne Reichert, Andreas S. Reigada, David Reiling, Jan H. Rein, Theo Reipert, Siegfried Rekha, Rokeya Sultana Ren, Hongmei Ren, Jun Ren, Weichao Renault, Tristan Renga, Giorgia Reue, Karen Rewitz, Kim Ribeiro de Andrade Ramos, Bruna Riazuddin, S. Amer Ribeiro-Rodrigues, Teresa M. Ricci, Jean-Ehrland Ricci, Romeo Riccio, Victoria Richardson, Des R. Rikihisa, Yasuko Risbud, Makarand V. Risueño, Ruth M. Ritis, Konstantinos Rizza, Salvatore Rizzuto, Rosario Roberts, Helen C. Roberts, Luke D. Robinson, Katherine J. Roccheri, Maria Carmela Rocchi, Stephane Rodney, George G. Rodrigues, Tiago Rodrigues Silva, Vagner Ramon Rodriguez, Amaia Rodriguez-Barrueco, Ruth Rodriguez-Henche, Nieves Rodriguez-Rocha, Humberto Roelofs, Jeroen Rogers, Robert S. Rogov, Vladimir V. Rojo, Ana I. Rolka, Krzysztof Romanello, Vanina Romani, Luigina Romano, Alessandra Romano, Patricia S. Romeo-Guitart, David Romero, Luis C. Romero, Montserrat Roney, Joseph C. Rongo, Christopher Roperto, Sante Rosenfeldt, Mathias T. Rosenstiel, Philip Rosenwald, Anne G. Roth, Kevin A. Roth, Lynn Roth, Steven Rouschop, Kasper M.A. Roussel, Benoit D. Roux, Sophie Rovere-Querini, Patrizia Roy, Ajit Rozieres, Aurore Ruano, Diego Rubinsztein, David C. Rubtsova, Maria P. Ruckdeschel, Klaus Ruckenstuhl, Christoph Rudolf, Emil Rudolf, Rüdiger Ruggieri, Alessandra Ruparelia, Avnika Ashok Rusmini, Paola Russell, Ryan R. Russo, Gian Luigi Russo, Maria Russo, Rossella Ryabaya, Oxana O. Ryan, Kevin M. Ryu, Kwon-Yul Sabater-Arcis, Maria Sachdev, Ulka Sacher, Michael Sachse, Carsten Sadhu, Abhishek Sadoshima, Junichi Safren, Nathaniel Saftig, Paul Sagona, Antonia P. Sahay, Gaurav Sahebkar, Amirhossein Sahin, Mustafa Sahin, Ozgur Sahni, Sumit Saito, Nayuta Saito, Shigeru Saito, Tsunenori Sakai, Ryohei Sakai, Yasuyoshi Sakamaki, Jun-Ichi Saksela, Kalle Salazar, Gloria Salazar-Degracia, Anna Salekdeh, Ghasem H. Saluja, Ashok K. Sampaio-Marques, Belém Sanchez, Maria Cecilia Sanchez-Alcazar, Jose A. Sanchez-Vera, Victoria Sancho-Shimizu, Vanessa Sanderson, J. Thomas Sandri, Marco Santaguida, Stefano Santambrogio, Laura Santana, Magda M. Santoni, Giorgio Sanz, Alberto Sanz, Pascual Saran, Shweta Sardiello, Marco Sargeant, Timothy J. Sarin, Apurva Sarkar, Chinmoy Sarkar, Sovan Sarrias, Maria-Rosa Sarkar, Surajit Sarmah, Dipanka Tanu Sarparanta, Jaakko Sathyanarayan, Aishwarya Sathyanarayanan, Ranganayaki Scaglione, K. Matthew Scatozza, Francesca Schaefer, Liliana Schafer, Zachary T. Schaible, Ulrich E. Schapira, Anthony H.V. Scharl, Michael Schatzl, Hermann M. Schein, Catherine H. Scheper, Wiep Scheuring, David Schiaffino, Maria Vittoria Schiappacassi, Monica Schindl, Rainer Schlattner, Uwe Schmidt, Oliver Schmitt, Roland Schmidt, Stephen D. Schmitz, Ingo Schmukler, Eran Schneider, Anja Schneider, Bianca E. Schober, Romana Schoijet, Alejandra C. Schott, Micah B. Schramm, Michael Schröder, Bernd Schuh, Kai Schüller, Christoph Schulze, Ryan J. Schürmanns, Lea Schwamborn, Jens C. Schwarten, Melanie Scialo, Filippo Sciarretta, Sebastiano Scott, Melanie J. Scotto, Kathleen W. Scovassi, A. Ivana Scrima, Andrea Scrivo, Aurora Sebastian, David Sebti, Salwa Sedej, Simon Segatori, Laura Segev, Nava Seglen, Per O. Seiliez, Iban Seki, Ekihiro Selleck, Scott B. Sellke, Frank W. Selsby, Joshua T. Sendtner, Michael Senturk, Serif Seranova, Elena Sergi, Consolato Serra-Moreno, Ruth Sesaki, Hiromi Settembre, Carmine Setty, Subba Rao Gangi Sgarbi, Gianluca Sha, Ou Shacka, John J. Shah, Javeed A. Shang, Dantong Shao, Changshun Shao, Feng Sharbati, Soroush Sharkey, Lisa M. Sharma, Dipali Sharma, Gaurav Sharma, Kulbhushan Sharma, Pawan Sharma, Surendra Shen, Han-Ming Shen, Hongtao Shen, Jiangang Shen, Ming Shen, Weili Shen, Zheni Sheng, Rui Sheng, Zhi Sheng, Zu-Hang Shi, Jianjian Shi, Xiaobing Shi, Ying-Hong Shiba-Fukushima, Kahori Shieh, Jeng-Jer Shimada, Yohta Shimizu, Shigeomi Shimozawa, Makoto Shintani, Takahiro Shoemaker, Christopher J. Shojaei, Shahla Shoji, Ikuo Shravage, Bhupendra V. Shridhar, Viji Shu, Chih-Wen Shu, Hong-Bing Shui, Ke Shukla, Arvind K. Shutt, Timothy E. Sica, Valentina Siddiqui, Aleem Sierra, Amanda Sierra-Torre, Virginia Signorelli, Santiago Sil, Payel Silva, Bruno J. de Andrade Silva, Johnatas D. Silva-Pavez, Eduardo Silvente-Poirot, Sandrine Simmonds, Rachel E. Simon, Anna Katharina Simon, Hans-Uwe Simons, Matias Singh, Anurag Singh, Lalit P. Singh, Rajat Singh, Shivendra V. Singh, Shrawan K. Singh, Sudha B. Singh, Sunaina Singh, Surinder Pal Sinha, Debasish Sinha, Rohit Anthony Sinha, Sangita Sirko, Agnieszka Sirohi, Kapil Sivridis, Efthimios L. Skendros, Panagiotis Skirycz, Aleksandra Slaninová, Iva Smaili, Soraya S. Smertenko, Andrei Smith, Matthew D. Soenen, Stefaan J. Sohn, Eun Jung Sok, Sophia P. M. Solaini, Giancarlo Soldati, Thierry Soleimanpour, Scott A. Soler, Rosa M. Solovchenko, Alexei Somarelli, Jason A. Sonawane, Avinash Song, Fuyong Song, Hyun Kyu Song, Ju-Xian Song, Kunhua Song, Zhiyin Soria, Leandro R. Sorice, Maurizio Soukas, Alexander A. Soukup, Sandra-Fausia Sousa, Diana Sousa, Nadia Spagnuolo, Paul A. Spector, Stephen A. Srinivas Bharath, M. M. St. Clair, Daret Stagni, Venturina Staiano, Leopoldo Stalnecker, Clint A. Stankov, Metodi V. Stathopulos, Peter B. Stefan, Katja Stefan, Sven Marcel Stefanis, Leonidas Steffan, Joan S. Steinkasserer, Alexander Stenmark, Harald Sterneckert, Jared Stevens, Craig Stoka, Veronika Storch, Stephan Stork, Björn Strappazzon, Flavie Strohecker, Anne Marie Stupack, Dwayne G. Su, Huanxing Su, Ling-Yan Su, Longxiang Suarez-Fontes, Ana M. Subauste, Carlos S. Subbian, Selvakumar Subirada, Paula V. Sudhandiran, Ganapasam Sue, Carolyn M. Sui, Xinbing Summers, Corey Sun, Guangchao Sun, Jun Sun, Kang Sun, Meng-xiang Sun, Qiming Sun, Yi Sun, Zhongjie Sunahara, Karen K.S. Sundberg, Eva Susztak, Katalin Sutovsky, Peter Suzuki, Hidekazu Sweeney, Gary Symons, J. David Sze, Stephen Cho Wing Szewczyk, Nathaniel J. Tabęcka-Łonczynska, Anna Tabolacci, Claudio Tacke, Frank Taegtmeyer, Heinrich Tafani, Marco Tagaya, Mitsuo Tai, Haoran Tait, Stephen W. G. 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Tong, Chun-Kit AS 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C1 Life Sciences Institute and Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt; Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy Johannes Gutenberg University, Institute of Pharmaceutical and Biomedical Sciences, Department of Pharmaceutical Biology, Mainz, Germany Medical University of Graz, Division of Cardiology, Graz, Austria Pasteur institute of Iran, Department of Hepatitis and HIV, Tehran, Iran. Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry, Halle (Saale), Germany Hebrew University of Jerusalem, Department of Biochemistry and Food Science, Rehovot, Israel Danish Cancer Society Research Center, RNA and Autophagy Group, Copenhagen, Denmark University of Copenhagen, Biotech Research and Innovation Centre, Copenhagen, Denmark University of Tromsø - The Arctic University of Norway, Department of Medical Biology, Tromsø, Norway Hospital Universitario de Canarias, Research Unit; CIBERNED and Universidad de La Laguna, ITB, Santa Cruz de Tenerife, Spain University of California, Davis, Division of Rheumatology, Allergy and Clinical Immunology, School of Medicine, Sacramento, CA, USA University of Toronto, Department of Biochemistry, Toronto, Ontario, Canada Medical University Innsbruck, Department of Medicine I, Innsbruck, Austria University of Calabria, Department of Pharmacy, Health and Nutritional Sciences, Arcavacata di Rende (CS), Italy National Institutes of Health, National Eye institute, Protein Structure and Function Section, Bethesda, MD, USA Ben-Gurion University of the Negev, Faculty of Health Sciences, Department of Clinical Biochemistry and Pharmacology, Beer-Sheva, Israel University of Alabama at Birmingham, Division of Nephrology and Birmingham VA Medical Center, Birmingham, AL, USA Inflammation Research Center, San Diego, CA, USA University of Palermo, Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche (STEBICEF), Palermo, Italy Cell Death Research & Therapy (CDRT) Lab, Department of Cellular & Molecular Medicine, Center for Cancer Biology, VIB-KU Leuven, Leuven, Belgium Indian Institute of Technology, Ropar, India University of Dundee, School of Life Sciences, MRC Protein Phosphorylation and Ubiquitylation Unit, Dundee, UK University of Texas Medical Branch, Department of Pathology, Galveston, TX, USA Colby College, Department of Biology, Waterville, ME, USA University of Maryland School of Medicine, Departments of Otorhinolaryngology Head & Neck Surgery, Ophthalmology and Visual Science, Baltimore, MD, USA Universidad Mayor, Center for Integrative Biology, and Geroscience Center for Brain Health and Metabolism, Santiago, Chile Lund University, Department of Experimental Medical Science, Cell Death, Lysosomes and Artificial Intelligence Group, Lund, Sweden Nihon University, College of Bioresource Sciences, Fujisawa, Kanagawa, Japan Koç University School of Medicine, Department of Molecular Biology and Genetics and KUTTAM Research Center for Translational Medicine, Istanbul, Turkey University of Crete, School of Medicine, Laboratory of Clinical Microbiology and Microbial Pathogenesis, Voutes, Heraklion, Crete, Greece; Foundation for Research and Technology, Institute of Molecular Biology and Biotechnology (IMBB), Heraklion, Crete, Greece University of Crete, School of Medicine, Laboratory of Clinical Microbiology and Microbial Pathogenesis, Voutes, Heraklion, Crete, Greece The Institute of Cancer Research, Cancer Therapeutics Unit, Sutton, UK Pharmaceutical Sciences Department, College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates University of Sydney, Department of Pathology and Bosch Institute, Sydney, NSW, Australia Insight Institute of Neurosurgery & Neuroscience, Department of Research, Flint, MI, USA McGill University, Departments of Medicine and Oncology and Segal Cancer Centre, Montreal, Quebec, Canada Technical University Dresden, Center for Molecular and Cellular Bioengineering (CMCB), Biotechnology Center (BIOTEC), Department of Cellular Biochemistry, Dresden, Germany Universidad de Sevilla, Departamento de Psicología Experimental, Facultad de Psicología, Sevilla, Spain Sapienza University of Rome, Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Rome, Italy The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA University of Rajshahi, Department of Pharmacy, Rajshahi, Bangladesh Department of Biological Sciences and Biotechnology, Faculty of Sciences, Islamic University of Gaza, Gaza 108, Palestine Department of Human Anatomy and Cell Science, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada University of Barcelona, Faculty of Pharmacy, Department of Biochemistry and Physiology, Barcelona, Spain Metabolism and Cancer Laboratory, Molecular Mechanisms and Experimental Therapy in Oncology Program (Oncobell), Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain The Francis Crick Institute, Molecular Cell Biology of Autophagy, London, UK Cleveland Clinic, Department of Cancer Biology, Cleveland, OH, USA University of the Basque Country, Instituto Biofisika (UPV/EHU, CSIC), and Department of Biochemistry and Molecular Biology, Leioa, Spain Instituto de Investigaciones en Ingeniería Genética y Biología Molecular “Dr. Héctor N. Torres”, Laboratorio de señalización y mecanismos adaptativos en Tripanosomátidos, Buenos Aires, Argentina; Universidad de Buenos Aires, Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Buenos Aires, Argentina Laboratory of Host-Pathogen Dynamics, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA The Wistar Institute, Philadelphia, PA, USA Buenos Aires University, Biochemistry and Pharmacy School, Deparment of Microbiology Immunology Biotechnology and Genetic, IDEHU, CABA, Argentina Universidade do Porto, i3S-Instituto de Investigação e Inovação em Saúde, Porto, Portugal; IPATIMUP - Institute of Molecular Pathology and Immunology of the University of Porto, Cancer Drug Resistance Group, Porto, Portugal; FFUP - Faculty of Pharmacy of the University of Porto, Department of Biological Sciences, Porto, Portugal Université Côte d'Azur, INSERM, CNRS, IPMC, team labeled Laboratory of Excellence (LABEX) Distalz, Valbonne, France Islamic University of Gaza, Department of Medical Laboratory Sciences, Faculty of Health Sciences, Gaza, Palestine University of Pavia, Department of Drug Sciences, Pharmacology Unit, Pavia, Italy University of Camerino, School of Biosciences and Veterinary Medicine, Camerino, Italy University of Porto, Faculty of Pharmacy, UCIBIO, REQUIMTE, Porto, Portugal Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Naples, Italy Ohio State University, Department of Microbial Infection and Immunity, and the Infectious Disease Research Institute, Columbus, OH, USA Save as Ravi Manjithaya University of California, San Francisco, San Francisco, CA, USA Aarhus University, Department of Molecular Biology and Genetics, Aarhus C, Denmark Departments of Pharmacology and Toxicology, and Neurology, The University of Alabama at Birmingham, Birmingham, AL, USA Federal University of São Paulo, Department of Medicine, Nephrology Division, Laboratory of Clinical and Experimental Immunology, São Paulo, SP, Brazil Universidade Nove de Julho (UNINOVE), Faculty of Pharmacy, São Paulo, SP, Brazil Cedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles CA, USA University of Bologna, Department of Pharmacy and Biotechnology, Bologna, Italy City of Hope Comprehensive Cancer Center, Beckman Research Institute, Department of Diabetes Complications and Metabolism, Duarte, CA, USA University of Tennessee, Department of Chemical and Biomolecular Engineering, Knoxville, TN, USA Northeast Ohio Medical university, Department of Anatomy & Neurobiology, Rootstown, OH, USA iNOVA4Health Chronic Diseases Research Center (CEDOC), Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisboa, Portugal Max Planck Institute for Biology of Ageing and CECAD, University of Cologne, Germany School of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol, UK University of Helsinki, Molecular and Integrative Biosciences Research Programme, Helsinki, Finland INSERM, U1231, Dijon, France University of Valencia, Faculty of Medicine, Department of Pharmacology, Valencia, Spain; CIBERehd (Centre for Networked Biomedical Research in Hepatic and Digestive Diseases), Valencia, Spain National Institute of Neuroscience, National Center of Neurology and Psychiatry, Department of Peripheral Nervous System Research, Kodaira, Tokyo, Japan Osaka University, Graduate School of Dentistry, Osaka, Japan Tokyo University of Pharmacy and Life Sciences, School of Life Sciences, Hachioji, Horinouchi, Tokyo, Japan Universidade Federal de Viçosa, Departamento de Biologia Vegetal, Viçosa, MG, Brazil The Jikei University School of Medicine, Division of Respiratory Disease, Departent of Internal Medicine, Tokyo, Japan Newcastle University, Biosciences Institute, Newcastle Upon Tyne, UK Instituto Cajal, Consejo Superior de Investigaciones Científicas (CSIC) and CIBERFES, Madrid, Spain University of Seville, Faculty of Pharmacy, Department of Physiology, Seville, Spain Albert Einstein College of Medicine, Department of Medicine, Bronx, NY, USA Howard University College of Medicine, Department of Anatomy, Washington D.C., USA Tohoku University, Graduate School fo Life Sciences, Sendai, Miyagi, Japan University of Michigan, Life Sciences Institute, Ann Arbor, MI, USA Imperial College London, MRC Centre for Molecular Bacteriolgy and Infection, Department of Microbiology, London, UK Toulouse University, CNRS, UPS, Center for Integrative Biology (CBI), Research Center on Animal Cognition (CRCA), Toulouse, France Iowa State University, Department of Genetics, Development and Cell Biology, Roy J. Carver Co-Laboratory, Ames, IA, USA Universidad Nacional de Cordoba, Laboratorio de Oncohematología, Hospital Nacional de Clínicas, CONICET, Córdoba, Argentina York College/The City University of New York, Department of Biology, Jamaica, NY, USA Translational Genomics Group, Incliva Health Research Institute, Burjasot, Valencia, Spain; Interdisciplinary Research Structure for Biotechnology and Biomedicine (ERI BIOTECMED), University of Valencia, Burjasot, Valencia, Spain University of Palermo, Department of Biological, Chemical and and Pharmaceutical Sciences and Technologies, Palermo, Italy Albert Einstein College of Medicine, Department of Molecular Pharmacology, Bronx, NY, USA Faculty of Engineering and Natural Sciences, Sabanci University, Orta Mahalle, Üniversite Caddesi No. 27, Orhanlı, Tuzla, 34956 Istanbul, Turkey; Sabanci University Nanotechnology Research and Application Center (SUNUM), Tuzla, 34956, Istanbul, Turkey Meir Medical Center, Translational Hemato-Oncology Laboratory, Kfar-Saba, Israel; Tel Aviv University, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv, Israel The Institute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Magdalenka, Poland; Ludwig Boltzmann Institute for Digital Health and Patient Safety, Medical University of Vienna, Vienna, Austria; Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia, Bulgaria; Department of Pharmacognosy, University of Vienna, Vienna, Austria University of Pittsburgh Medical Center, Department of Critical Care Medicine, Department of Pediatrics, Safar Center for Resuscitation Research and the Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA University of Nice, Mediterranean Center for Molecular Medicine, Inserm U1065, Nice, France Imperial College London, Faculty of Medicine, London, UK Departments of Pharmacology and Microbiology, University of Maryland School of Medicine, Baltimore, MD, USA; Stanford University School of Medicine Stanford, CA, USA University of Turin, Department of Clinical and Biological Sciences, Turin, Italy University of Milan, Department of Health Sciences, Milano, Italy Universidad de Santiago de Chile, Faculty of Chemistry and Biology, Department of Biology, Santiago, Chile Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Neuroblastoma Laboratory, Padua, Italy CNC - Center for Neuroscience and Cell Biology, Coimbra, IIIUC - Instituto de Investigação Interdisciplinar, University of Coimbra, Coimbra, Portugal The Hebrew University of Jerusalem, Alexander Silberman Institute of Life Sciences, Department of Plant and Environmental Sciences, Edmond Safra Campus, Jerusalem, Israel Tulane Health Sciences Center, Department of Pathology and Laboratory Sciences, New Orleans, LA, USA Melbourne Dementia Research Centre, The Florey Institute of Neuroscience & Mental Health, The University of Melbourne, Parkville, VIC, Australia University of Arkansas for Medical Sciences, Department of Geriatrics, Little Rock, AR, USA University of Malta, Department of Physiology & Biochemistry, Msida, Malta Kogakuin University, Research Institute for Science and Technology, Hachioji, Tokyo, Japan Albert Einstein College of Medicine, Departments of Molecular Pharmacology and Biochemistry, Bronx, NY, USA Eastern Michigan University, Department of Chemistry, Ypsilanti, MI, USA Hanyang University, College of Pharmacy, Ansan, Gyeonggido, Korea Yonsei University College of Medicine, Severance Biomedical Science Institute, Seoul, Korea University of Massachusetts Medical School, Department of Molecular, Cell and Cancer Biology, Worcester, MA, USA Konkuk University, Department of Bioscience and Biotechnology, Seoul, Korea Ajou University, College of Pharmacy and Research Institute of Pharmaceutical Science and Technology (RIPST), Suwon, Korea Seoul National University, Department of Biological Sciences, Seoul, South Korea University of Calabria, Department of Pharmacy, Health Science and Nutrition, Section of Preclinical and Translational Pharmacology, Cosenza, Italy Adam Mickiewicz University/Faculty of Biology, Institute of Experimental Biology, Department of General Botany, Poznan, Poland Iowa State University, Department of Genetics, Development, and Cell Biology, Ames, IA, USA Kunming University of Science and Technology, Medical School, Kunming, Yunnan, China National Jewish Health, Department of Academic Affairs, Denver, CO, USA University of Texas Health Science Center at San Antonio, Department of Cell Systems and Anatomy, San Antonio, TX, USA Jadavpur University, Department of Mathematics, Centre for Mathematical Biology and Ecology, Kolkata, India Karolinska Institute, Department of Cell and Molecular Biology, Stockholm, Sweden University of Genoa, Department of Earth, Environment and Life Sciences, Genoa, Italy University of Siena, Department of Life Sciences, Siena, Italy University of Urbino Carlo Bo, Department of Biomolecular Sciences, Urbino (PU), Italy Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy; Baylor College of Medicine, Houston, TX, USA University of Naples Federico II, Department of Translational Medical Sciences, Naples, Italy Institute for Research and Technology in Food and Agriculture (IRTA), Animal Breeding and Genetics Programme, Caldes de Montbui, Spain Max Planck Institute of Molecular Plant Physiology, Potsdam-Golm, Germany UCL Queen Square Institute of Neurology, Reta Lila Weston Institute, London, UK Middle East Technical University, Department of Biological Sciences, Ankara, Turkey University of Miami, Department of Surgery and Sylvester Comprehensive Cancer Center, Miami, FL, USA University of Miami, Department of Surgery, Miami, FL, USA Université Côte D'Azur, CNRS, Inserm, Institut de Biologie Valrose, Nice, France School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China Universidade de São Paulo. Department of Biochemistry, Institute of Chemistry, Sao Paulo, Brazil University of Bologna, Department of Biomedical and Neuromotor Sciences, Bologna, Italy University of Rome Tor Vergata, Department of Biology, Rome, Italy; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Laboratory of Cell Signaling, Rome, Italy Edinburgh Napier University, School of Applied Sciences, Edinburgh, UK University of Michigan, Department of Neurology, Ann Arbor, MI, USA Pulmonology Department, Hospital del Mar-IMIM, Pompeu Fabra University, CIBERES, Barcelona, Spain University of Limerick, Department of Biological Sciences, Limerick, Ireland; University of Limerick, Health Research Institute, Limerick, Ireland Danish Cancer Society Research Center, Copenhagen, Denmark Rice University, Department of Biosciences, Houston, TX, USA Columbia University, Department of Medicine, New York, NY, USA Jawaharlal Nehru Centre for Advanced Scientific Research, Molecular Biology and Genetics Unit, and Neuroscience Unit, Autophagy Laboratory, Jakkur, Bangalore, India ICAR-Indian Veterinary Research Institute, FMD Vaccine Research Laboratory, Bengaluru, India The University of Texas M.D. Anderson Cancer Center, Department of Experimental Therapeutics, Houston, TX, USA University of North Texas Health Science Center, Department of Microbiology, Immunology & Genetics, Fort Worth, TX, USA University of Louvain, Louvain Institute of Biomolecular Science and Technology (LIBST), Louvain-la-Neuve, Belgium Trinity College Dublin, School of Medicine, Trinity Translational Medicine Institute, Dublin, Ireland Université Paris-Saclay, INSERM UMR1195, Hôpital Le Kremlin Bicêtre, 80 rue du Général Leclerc, 94276 Kremlin-Bicêtre, France University of South Carolina Upstate, Spartanburg, SC, USA Institut National de la Santé et de la Recherche Médicale (INSERM), Sorbonne Université, Université de Paris, Centre de Recherche des Cordeliers, Paris, France Francis Crick Institute, London, UK; UCL, Royal Free Hospital, London, UK Université Paris-Saclay, Inserm U1185, Le Kremlin-Bicêtre, France Université de Pau et des Pays de l’Adour, E2S UPPA, INRAE, NUMEA, 64310 Saint-Pée-sur-Nivelle, France University of Sao Paulo, Institute of Biomedical Sciences, Sao Paulo, SP, Brazil Emory University School of Medicine, Division of Endocrinology, Metabolism and Lipids, Atlanta, GA, USA University of Pennsylvania, Perelman School of Medicine, PENN Center for Pulmonary Biology, Lung Epithelial Biology Laboratories, Philadelphia, PA, USA Mater Research Institute, University of Queensland, Brisbane Australia Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology, München, Germany Hannover Medical School, Department for Clinical Immunology and Rheumatology, Hannover, Germany University of Rome “Tor Vergata”, Department of Clinical Sciences and Translational Medicine, Rome, Italy Tufts University, USDA Human Nutrition Research Center on Aging, Laboratory for Nutrition and Vision Research, Boston, MA, USA Universidad Cardenal Herrera-CEU, CEU Universities, School of Health Sciences, Department of Biomedical Sciences, Moncada, Spain Bar-Ilan University, Azrieli Faculty of Medicine, Safed, Israel University Medical Center of the Johannes Gutenberg University, Institute of Pathobiochemistry, Mainz, Germany Boston University, Metcalf Science Center, Boston, MA, USA Sorbonne Université, CNRS UMR8226, Institut de Biologie Physico-Chimique, Laboratoire de Biologie Moléculaire et Cellulaire des Eucaryotes, Paris, France Italian Liver Foundation, Trieste, Italy University of Rome “Sapienza”, Department of Clinical and Molecular Medicine, Laboratory affiliated to Istituto Pasteur Italia Fondazione Cenci Bolognetti, Rome, Italy Centro Nacional de Biotecnología-CNB-CSIC, Madrid, Spain Universidad Autónoma de Madrid, Departamento de Biología Molecular, Madrid, Spain University of São Paulo, Faculty of Pharmaceutical Sciences, Department of Pathophysiology, Sao Paulo, Brazil Universidad Mayor, Center for Integrative Biology, Santiago, Chile University of Oklahoma Health Sciences Center/Stephenson Cancer Center, Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, Oklahoma City, OK, USA UMR 7242 “Biotechnology and cellular signaling”, CNRS, Illkirch, France Washington University in Saint Louis, School of Medicine, Department of Psychiatry, Saint Louis MO, USA Universidad Francisco de Vitoria, Madrid, Spain Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute, Adelaide, Australia University of Copenhagen, Department of Biology, Copenhagen, Denmark University of Lausanne Hospital and Lausanne University, Institute of Pathology, Department of Laboratory Medicine and Pathology, Lausanne, Switzerland Queen Mary University of London, Blizard Institute, Centre for Cell Biology and Cutaneous Research, London, UK University of Cologne and University Hospital Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; Center for Molecular Medicine, Cologne, Germany University of Massachusetts Medical School, Department of Molecular, Cell and Cancer Biology (MCCB), Worcester, MA, USA Magna Graecia University, Department of Health Sciences, Catanzaro, Italy Université Paris Descartes, Institut Cochin, INSERM U1016, CNRS UMR8104, Paris, France CNRS, Université de Bordeaux, Laboratoire de Biogenèse Membranaire UMR5200, 33140 Villenave d'Ornon, Bordeaux, France; Université de Bordeaux, CNRS, Laboratoire de Biogenèse Membranaire UMR5200, Villenave d'Ornon, Bordeaux, France Université du Québec à Trois-Rivières, Département de Biologie Médicale, Trois-Rivières, Québec, Canada University of Michigan, Department of Ophthalmology and Visual Sciences, Ann Arbor, MI, USA University of Montpellier, CNRS/UMR5235 LPHI, Montpellier, France Bristol Medical School, University of Bristol, Bristol, UK Ghent University, VIB Center for Inflammation Research, Ghent, Belgium University of Oxford, Kennedy Institute of Rheumatology, Oxford, UK University of New Mexico, Department of Molecular Genetics and Microbiology, Department of Neurology, Albuquerque, NM, USA Comenius University, Department of Biochemistry, Bratislava, Slovakia University of Oklahoma Health Sciences Center, Department of Obstetrics and Gynecology, Oklahoma City, OK, USA Vanderbilt University Medical Center, Vanderbilt Eye Institute, Nashville, TN, USA Department of Biophysics, Post Graduate Institute of Medical Education and Research, Chandigarh, India Louisiana State University Health Sciences Center-Shreveport, Department of Pathology and Translational Pathobiology, Shreveport, LA, USA National Institute of Technology Rourkela, Department of Life Science, Cancer and Cell Death Laboratory, Rourkela, Odisha, India Michigan Technological University, Department of Chemistry, Houghton, MI, USA Dalian Medical University, College of Basic Medical Sciences, Dalian, China Garvan Institute of Medical Research, St Vincent's Medical School, Faculty of Medicine, UNSW, Sydney, Australia Eötvös Loránd University (ELTE), Department of Genetics, Budapest, Hungary Federal University of São Paulo, Department of Pharmacology, Paulista School of Medicine, São Paulo, Brazil University Hospital of North Norway, The Heart and Lung Clinic; University of Tromso-The Artic University of Norway, Department of Clinical Medicine, Tromso, Norway Norwegian University of Science and Technology, Department of Biomedical Laboratory Science, Trondheim, Norway University of York, Department of Biology, Heslington, UK University of Valencia, Faculty of Medicine, Department of Physiology, Valencia, Spain; CIBERehd, Valencia, Spain University of Lodz, Faculty of Biology and Environmental Protection, Lodz, Poland Linköping University, Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping, Sweden Karolinska Institutet, Department of Women's and Children’s Health, Stockholm, Sweden AND Karolinska University Hospital, Pediatric Oncology, Stockholm, Sweden Indiana University School of Medicine, Department of Microbiology and Immunology, Indianapolis, IN, USA St. Jude Children's Research Hospital, Department of Immunology, Memphis, TN, USA University of Zagreb, School of Medicine, Croatian Institute for Brain Research, Zagreb, Croatia University of Pennsylvania, Department of Basic and Translational Sciences, Philadelphia, PA, USA Burnet Institute, Melbourne, Australia University College Cork, Department of Pharmacology and Therapeutics, County Cork, Ireland INMG, INSERM, CNRS, University of Lyon, Lyon, France University of Padova, Department of Molecular Medicine, Padova, Italy Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Neurosciences and Cellular and Structural Biology Division (NCSBD), Bethesda, MD, USA West Virginia University, Department of Surgery, Morgantown, WV, USA The Open University, School of Life, Health and Chemical Sciences, Faculty of Science, Technology, Engineering and Mathematics, Milton Keynes, UK University of Rome Tor Vergata, Department of Biology, Rome, Italy IRCCS Bambino Gesù Children’s Hospital, Department of Pediatric Hemato-Oncology and Cell and Gene Therapy, Rome, Italy Albert Ludwigs University of Freiburg, Faculty of Medicine, Institute of Molecular Medicine and Cell Research, Freiburg, Germany University Children’s Hospital Zurich, Children’s Research Center and Department of Oncology, Zurich, Switzerland University of Texas M.D. Anderson Cancer Center, Department of Leukemia, Houston, TX, USA Case Western Reserve University School of Medicine, Department of Pediatrics, Cleveland, OH, USA; InterRayBio, LLC, Baltimore, MD, USA Washington State University, Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Pullman, WA, USA University Santiago de Compostela, Department of Pharmacology, Veterinary Faculty, Lugo, Spain Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute and Department of Molecular and Human Genetics, Houston, TX, USA Université de Paris, PARCC, INSERM, Paris, France University of Alabama at Birmingham, Department of Ophthalmology and Visual Sciences, Birmingham, AL, USA Albert Einstein College of Medicine, Department of Developmental and Molecular Biology, Bronx, NY, USA Medical University of Graz, Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology and Biochemistry, Graz, Austria University Paris 13, UMR_S942 Inserm; University of Paris, Bobigny, France Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala BioCenter, Department of Molecular Sciences, Uppsala, Sweden Stanford University, Department of Chemical & Systems Biology, Stanford, CA, USA Imperial College London, Department of Life Sciences, London, UK The Connecticut Agricultural Experiment Station, Center for Vector Biology and Zoonotic Diseases, Department of Environmental Sciences, New Haven, CT, USA Goethe University, University Hospital, University Cancer Center Frankfurt (UCT), Department of Medicine, Hematology/Oncology, Frankfurt, Germany Danube Private University, Department of Medicine/Dental Medicine, Krems/Donau, Austria Georg-August-Universität Göttingen, Institute for Microbiology and Genetics, Department of Molecular Microbiology and Genetics, Göttingen, Germany Universidad de Chile, Instituto de Nutrición y Tecnología de los Alimentos (INTA), Santiago, Chile Université de Paris, Sorbonne Université, Centre de Recherche des Cordeliers, INSERM U1138, Paris, France University Côte d'Azur (UCA), Institute for Research on Cancer and Aging of Nice (IRCAN), Centre National de la Recherche Scientifique (CNRS) UMR7284, Institut National de la Santé et de la Recherche Médicale (INSERM) U1081, Nice, France Centre des Sciences du Goût et de l'Alimentation, AgroSup Dijon, CNRS, INRAE, University of Bourgogne Franche-Comté, Eye and Nutrition Research Group, Dijon, France National Autonomous University of Mexico, Faculty of Chemistry, Department of Biology, Mexico city, Mexico University of California San Francisco, Department of Medicine, Zuckerberg San Francisco General Hospital and TraumaCenter, San Francisco, CA, USA University of Copenhagen, Department of Biology, Denmark University of Pittsburgh, Department of Biological Sciences, Pittsburgh, PA, USA Washington University School of Medicine, Department of Medicine, Saint Louis, MO, USA Department of Human Genetics, Genentech, Inc., South San Francisco, CA, USA David Geffen School of Medicine at UCLA, Department of Neurology, Los Angeles, CA, USA University of Colorado, AMC, Department of Pharmacology, Aurora, CO, USA University of Minnesota, Hormel Institute, Austin, MN, USA University of Sao Paulo, School of Physical Education and Sport, Cellular and Molecular Exercise Physiology Laboratory, Sao Paulo, SP, Brazil Hospital for Sick Children, Cell Biology Program, Toronto, ON, Canada University of Insubria, Department of Biotechnology and Life Sciences, Varese, Italy Monash University, School of Biological Sciences, Melbourne, Victoria, Australia University of Salento, Dept of Biological and Environmental Sciences and Technologies, Lecce, Italy Institut Pasteur, Biologie des Bactéries Intracellulaires and CNRS UMR 3525, Paris, France University of Pittsburgh, Aging Institute, Department of Medicine, Pittsburgh, PA, USA University Duisburg-Essen, Essen University Hospital, Department of Gastroenterology and Hepatology, Essen, Germany; Department of Gastroenterology, Hepatology & Endocrinology, Hannover Medical School, Hannover, Germany Thomas Jefferson University, Department of Pathology, Anatomy, and Cell Biology, Philadelphia, PA, USA Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA University of Arizona, Department of Molecular and Cellular Biology, Tucson, AZ, USA University of Iowa, Iowa City, IA, USA Montana BioAg. Inc. Missoula, MT, USA Universidad de Chile, Facultad de Odontología, Autophagy Research Center (ARC), Santiago, Chile KU Leuven, Department of Cellular & Molecular Medicine, Campus Gasthuisberg, Leuven, Belgium University of Medicine and Pharmacy of Craiova, Department of Medical Genetics, Craiova, Romania King's College London, School of Cardiovascular Medicine & Sciences, The Rayne Institute, St Thomas' Hospital, London, UK University of Cordoba, Department of Cell Biology, Physiology and Immunology, Córdoba, Spain The Rockefeller University, Laboratory of Cellular and Molecular Neuroscience, New York, NY, USA Stockholm University, The Wenner-Gren Institute, Department of Molecular Biosciences, Stockholm, Sweden University of Verona, Department of Neurosciences, Biomedicine and Movement Sciences, Biological Chemistry Section, Verona, Italy Departmento de Biología Celular e Histología, Facultad de Biología, Universidad de Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB)-Arrixaca, Murcia, Spain Universidad Nacional Autónoma de México, Faculty of Sciences, Department of Cell Biology, Fibrosis Lab, Mexico City, Mexico New York University School of Medicine, Skirball Institute and Department of Microbiology, New York, NY, USA Wenzhou Medical University, State Key Laboratory of Ophthalmology, Optometry and Visual Science, School of Optometry and Ophthalmology and the Eye Hospital, Wenzhou, China University of Louisville, Pediatric Research Institute, Department of Pediatrics, Louisville, KY, USA Rutgers University, The State University of New Jersey, Department of Cell Biology and Neuroscience, Piscataway, NJ, USA University of Barcelona, Department of Biochemistry and Molecular Biomedicine, and Network Center for Biomedical Research in Pathophysiology of Obesity and Nutrition (CIBEROBN), Barcelona, Spain University of Las Palmas de Gran Canaria, Department of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), Las Palmas de Gran Canaria, Spain; Norwegian School of Sport Sciences, Department of Physical Performance, Oslo, Norway University of Alabama, Department of Biological Sciences, Tuscaloosa, AL, USA University of Georgia, Department of Kinesiology, Athens, GA, USA Fondazione Policlinico Universitario “Agostino Gemelli” IRCCS, Rome, Italy University of Zaragoza, Faculty of Veterinary-IIS Aragón, IA2-CITA, CIBERNED, Laboratory of Genetics and Biochemistry (LAGENBIO), Zaragoza, Spain University of São Paulo, Department of Immunology, Laboratory of Transplantation Immunobiology, São Paulo, SP, Brazil CNRS, Institut Curie, Paris, France University of Bordeaux, CNRS, IBGC, UMR 5095, Bordeaux, France University of London, The Royal Veterinary College, Department of Comparative Biomedical Sciences, UCL Consortium for Mitochondrial Research, London, UK Loyola University, Stritch School of Medicine, Department of Microbiology and Immunology, Chicago, IL, USA University of Ottawa, Department of Chemistry and Biomolecular Sciences and Department of Biochemistry, Microbiology and Immunology, Host-Microbe Interactions Laboratory, Ottawa, ON, Canada University of Rome “Tor Vergata”, Department of Biology, Rome, Italy Università di Sassari, Dipartimento di Scienze Biomediche, Sassari, Italy Université Côte d'Azur, Université Nice Sophia Antipolis, CEA/DRF/BIAM, Faculté de Médecine, UMR E-4320 TIRO-MATOs, Nice, France Universidad San Sebastián, Centro de Biología Celular y Biomedicina (CEBICEM), Facultad de Medicina y Ciencia, Santiago, Chile University of Toronto, Sinai Health System, Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada IRBLleida-University of Lleida,Department of Experimental Medicine, Lleida, Spain Xiamen University School of Medicine, Fujian Provincial Key Laboratory of Reproductive Health Research, Xiang'an, Xiamen, China University of Campania “L. Vanvitelli”, Department of Precision Medicine, Naples, Italy; Institute of Genetic Research, Biogem scarl, Laboratory of Molecular and Precision Oncology, Ariano Irpino (AV), Italy Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, Universidade da Coruña (UDC), A Coruña, Spain University of Wisconsin, Department of Surgery, Madison, WI, USA University of Geneva, Department of Biochemistry, Faculty of Science, Switzerland Universidad Nacional Autónoma de México, Institute of Biotechnology, Plant Molecular Biology Department, Cuernavaca, Morelos, México University of Coimbra, Faculty of Medicine and CNC-Center for Neuroscience and Cell Biology, Coimbra, Portugal University of Arizona Cancer Center, Tucson, AZ, USA Université Côte d'Azur, Université Nice Sophia Antipolis, CEA/DRF/Institut Frédéric Joliot, Faculté de Médecine, UMR E-4320 TIRO-MATOs, Nice, France Trev and Joyce Deeley Research Centre, BC Cancer, Victoria, British Columbia, Canada University of Graz, Institute of Molecular Biosciences, NAWI Graz, Graz, Austria Federal University of Rio de Janeiro, Institute of Microbiology, Department of Immunology, Rio de Janeiro, Brazil Polytechnic University of Marche, Department of Life and Environmental Sciences, Ancona, Italy University of Modena and Reggio Emilia, Department of Biomedical, Metabolic and Neural Sciences, Modena, Italy Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR7258, Aix-Marseille Université U105, Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France Functional Genomics of Cardiomyopathies, Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany University of Alabama at Birmingham, Department of Medicine, Pulmonary, Allergy, and Critical Care Medicine, Birmingham VA Medical Center, Birmingham, AL, USA Universidade de Lisboa, Faculty of Pharmacy, Research Institute for Medicines (iMed.ULisboa), Lisboa, Portugal Aix Marseille Univ, CNRS, LISM, Institut de Microbiologie de la Méditerranée, Marseille, France Universitat Autònoma de Barcelona, Institute of Neuroscience, Barcelona, Spain Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Department of Biological Chemistry; Networking Biomedical Research Centre on Hepatic and Digestive Diseases (CIBER-EHD), Barcelona, Spain University of New Mexico Health Sciences Center, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Albuquerque, NM, USA Universidad de Valparaíso, Centro Interdisciplinario de Neurociencia de Valparaíso, Laboratory of Molecular Sensors, Valparaíso, Chile Complutense University, Instituto de Investigaciones Sanitarias San Carlos (IdISSC), Department of Biochemistry and Molecular Biology, School of Biology, Madrid, Spain Université de Paris, Sorbonne Université, Centre de Recherche des Cordeliers, INSERM U1138, Team “Metabolism, Cancer & Immunity”, Paris, France; Gustave Roussy Cancer Campus, Metabolomics and Cell Biology Platforms, Villejuif, France Division of Medical Genetics, Fondazione IRCCS-Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy Universidad de Concepción, Department of Biochemistry and Molecular Biology, Concepción, Chile Universidade NOVA de Lisboa, Faculdade de Ciências e Tecnologia, Departamento Ciências da Vida, UCIBIO, Caparica, Portugal Universidad de La Laguna, Departamento de Ciencias Médicas Básicas, Tenerife, Spain Universidad Nacional Autónoma de México (UNAM), Instituto de Fisiologia Celular, Ciudad Universitaria, Ciudad de México, México The Scripps Research Institute, Department of Molecular Medicine, La Jolla, CA, USA University of Coimbra, Portugal, CNC – Center for Neuroscience and Cell Biology & Faculty of Pharmacy, Coimbra, Portugal University of Pisa, Interdepartmental Research Centre on Biology and Pathology of Aging, Pisa, Italy University of Innsbruck, Institute for Biomedical Aging Research, Department of Molecular Biology, Innsbruck, Austria Biomedical Research Institute of Murcia, IMIB-Arrixaca, Telomerase, Cancer and Aging Group, Surgical Department, Murcia, Spain Research Center Borstel, Leibniz Lung Center, Priority Area Infections, Division Cellular Microbiology, Borstel, Germany Danish Cancer Society Research Center, Center for Autophagy, Recycling and Disease (CARD), Cell Stress and Survival Unit, Copenhagen, Denmark; IRCCS Bambino Gesù Children’s Hospital, Department of Pediatric Hemato-Oncology and Cell and Gene therapy, Rome, Italy; University of Rome Tor Vergata, Department of Biology, Rome, Italy Medical University of Bialystok, Department of Pharmaceutical Biochemistry, Bialystok, Poland Ospedale San Raffaele and Vita-Salute San Raffaele University, Division of Genetics and Cell Biology, Milano, Italy Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili, Madrid, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain University of Minho, School of Medicine, Life and Health Sciences Research Institute (ICVS), Braga, Portugal Universidade Federal de São Paulo, Department of Morphology and Genetics, São Paulo, SP, Brazil University of Tuscia, Department for Innovation in Biological, Agro-food, and Forest systems (DIBAF), Viterbo, Italy Ege University, Faculty of Medicine, Department of Medical Biology, Izmir, Turkey School of Pharmacy, Jeonbuk National University, Jeollabuk-do, Republic of Korea Karolinska Institutet, Department of Physiology and Pharmacology, Stockholm, Sweden Kaohsiung Medical University, Department of Pathology, Kaohsiung City, Taiwan University of Calcutta, Department of Biotechnology and Dr. B.C. Guha Centre for Genetic Engineering and Biotechnology, Kolkata, India Saha Institute of Nuclear Physics, Biophysics & Structural Genomics Division, HBNI, Kolkata, India Ehime University, Department of Aquatic Life Sciences, Ainan, Ehime, Japan Justus-Liebig-University Giessen, Institute of Medical Microbiology, Giessen, Germany The University of Hong Kong, Li Ka Shing Faculty of Medicine, Department of Obstetrics and Gynecology, Hong Kong, China Queen's University, Department of Biomedical and Molecular Sciences, Kingston, Ontario, Canada The Chinese University of Hong Kong, School of Life Sciences, Shatin N.T., Hong Kong, China The Chinese University of Hong Kong, School of Biomedical Sciences, Hong Kong, China The Chinese University of Hong Kong, Department of Anaesthesia and Intensive Care, Hong Kong, China Tulane University School of Medicine, Department of Pharmacology, New Orleans, LA, USA National Cheng Kung University, College of Medicine, Department of Microbiology and Immunology, Tainan, Taiwan University of California, Berkeley, Department of Molecular Biology and Cell Biology, Berkeley, CA, USA; University of California, Berkeley, California Institute for Quantitative Biosciences, Berkeley, CA, USA National University of Singapore, Faculty of Sciences, Department of Pharmacy, Singapore Southeast University, School of Medicine, Department of Physiology, Nanjing, Jiangsu, China University of East Anglia, School of Biological Sciences, Norwich Research Park, UK Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, University of Strasbourg, Illkirch, France NCR Biotech Science Cluster, Translational Health Science and Technology Institute, Complex Analysis Group, Faridabad, India Banaras Hindu University, Institute of Science, Department of Zoology, Lanka, Varanasi, Uttar Pradesh, India University of Washington, Department of Laboratory Medicine, Seattle, WA, USA Institute of Life Sciences, Bhubaneswar, Odisha, India UCL Institute of Ophthalmology, London, UK National Cheng Kung University, Department of Biochemistry and Molecular Biology, Tainan, Taiwan Academia Sinica, Institute of Biological Chemistry, Taipei, Taiwan University of Southern California, Center for Craniofacial Molecular Biology, Los Angeles, CA, USA University of Minnesota Medical School, Department of Laboratory Medicine and Pathology, Minneapolis, MN, USA Qingdao University, Institute of Brain Science and Disease, Qingdao, Shandong, China Army Medical University (Third Military Medical University), Daping Hospital, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Laboratory for the Prevention and Rehabilitation of Training Related Injuries, Chongqing, China Third Military Medical University, Southwest Hospital, Institute of Pathology and Southwest Cancer Centre, Chongqing, China Changhua Christian Hospital, Department of Otorhinolaryngology-Head and Neck Surgery, Changhua, Taiwan Wuhan Sports University, College of Health Science, Tianjiu Research and Development Center for Exercise Nutrition and Foods, Hubei Key Laboratory of Exercise Training and Monitoring, Wuhan, Hubei, China College of Life Sciences, Nankai University, Tianjin, China Wuhan University, School of Pharmaceutical Sciences, Zhongnan Hospital, Wuhan, China Duke University, Department of Medicine, Durham, NC, USA Chinese Academy of Sciences, Institute of Modern Physics, Lanzhou, China University of Sydney, Sydney Medical School, Renal Medicine, St Leonards, NSW, Australia Temple University, Lewis Katz School of Medicine, Cardiovascular Research Center and Department of Physiology, Philadelphia, PA, USA Chinese Academy of Medical Sciences and Peking Union Medical College, Institute of Dermatology, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing, Jiangsu, China Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China Tsinghua University, School of Life Sciences, Beijing, China Peking University School of Basic Medical Science, Department of Immunology, Beijing, China Research Institute in Oncology and Hematology, CancerCare Manitoba, Winnipeg, Manitoba, Canada Mackay Memorial Hospital, Department of Radiation Oncology, Taipei, Taiwan Sun Yat-sen University, School of Life Science, Guangzhou, China Wuhan University, School and Hospital of Stomatology, Key Lab of Oral Biomedicine of Ministry of Education (KLOBME), Wuhan, Hubei, China 2nd Affiliated Hospital of Zhejiang University School of Medicine, Department of Respiratory and Critical Care Medicine, Hangzhou, China University of Texas Southwestern Medical Center, Department of Molecular Biology, Dallas, Texas, USA Purdue University, Department of Botany and Plant Pathology, West Lafayette, IN, USA Wuhan University, Hubei Key laboratory of Cell Homeostasis, College of Life Sciences, Wuhan, China Capital Medical University, Beijing Ditan Hospital, Liver Disease Center, Beijing, China Northwestern University Feinberg School of Medicine, Department of Neurology & Lou & Jean Malnati Brain Tumor Institute, Chicago, IL, USA Albert Einstein College of Medicine, Department of Genetics, Bronx, NY, USA The University of Texas Health Science Center at Houston, Department of Integrative Biology and Pharmacology, Houston, TX, USA National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA East China Normal University, School of Life Sciences, Shanghai, China University of Florida, Food Science and Human Nutrition Department, Gainesville, FL, USA Zhejiang University, College of Pharmaceutical Sciences, Institute of Pharmacology and Toxicology, Hangzhou, Zhejiang, China National Cancer Center Korea, Goyang, Gyeonggi, Korea National University of Singapore, Yong Loo Lin School of Medicine, Department of Biochemistry, Singapore National University of Singapore, Yong Loo Lin School of Medicine, Strategic Research Programme in Precision Medicine, Singapore Lomonosov Moscow State University, A.N. Belozersky Institute of Physico-Chemical Biology, Moscow, Russia University of Pennsylvania, Department of Pathology and Laboratory Medicine, Philadelphia, PA, USA National Cheng Kung University, College of Medicine, Department of Pharmacology, Tainan, Taiwan Sun Yat-Sen University, School of Pharmaceutical Sciences, Guangzhou, China INSERM U1242, University of Rennes, Rennes, France; Centre de Lutte Contre le Cancer Eugène Marquis, Rennes, France University of North Carolina at Charlotte, Department of Biological Sciences, Charlotte, NC, USA The University of Hong Kong, Queen Mary Hospital, Department of Paediatrics and Adolescent Medicine, Pokfulam, Hong Kong, China University of Milano-Bicocca, Department of Biotechnology and Biosciences, Milan, Italy Istituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Siena, Italy; Core Research Laboratory, Istituto per lo Studio, la Prevenzione e la Rete Oncologica, Siena, Italy. The Norwegian Radium Hospital, Institute for Cancer Research, Department of Molecular Cell Biology, Montebello, Oslo, Norway; University of Oslo, Faculty of Mathematics and Natural Sciences, The Department of Biosciences, Oslo, Norway The Norwegian Radium Hospital, Institute for Cancer Research, Department of Molecular Cell Biology, Montebello, Oslo, Norway; University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Centre for Cancer Cell Reprogramming, Oslo, Norway IEO, European Institute of Oncology IRCCS, IFOM-IEO Campus, Department of Experimental Oncology, Milan, Italy University of Chile, Faculty of Chemical and Pharmaceutical Sciences, Advanced Center for Chronic Diseases (ACCDiS), Santiago, Chile Taipei Veterans Generals Hospital, Department of Medical Research, Taipei, Taiwan. National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Rocky Mountain Laboratories (RML), Laboratory of Virology, Innate Immunity and Pathogenesis Section, Hamilton, MT, USA Institute of Translational Pharmacology, National Research Council, Rome, Italy; European Center for Brain Research, Laboratory of Resolution of Neuroinflammation, IRCCS Santa Lucia Foundation, Rome, Italy Kyungpook National University, Department of Life Science, Deagu, Korea Wonkwang University School of Medicine, Department of Microbiology, Iksan, Jeonbuk, Korea Weill Cornell Medicine, Department of Medicine, New York, NY, USA Weill Cornell Medicine, Division of Nephrology and Hypertension, Joan and Sanford I. Weill Department of Medicine, New York, NY, USA CSIR-Indian Institute of Chemical Biology, Kolkata, India BC Cancer Research Centre, Department of Experimental Therapeutics, Vancouver, BC, Canada University of Pittsburgh School of Medicine, Department of Pathology, Pittsburgh, PA, USA National University of Singapore, Yong Loo Lin School of Medicine, Department of Physiology; National University of Singapore, LSI Neurobiology Programme; National University of Singapore, Institute for Health Innovation and Technology; National University Hospital Singapore, Centre for Healthy Longevity; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore Konkuk University School of Medicine, Department of Ophthalmology, Seoul, Korea Max-Planck-Institut für Molekulare Pflanzenphysiologie, Potsdam, Germany University of Ulsan College of Medicine, Asan Medical Center, Department of Psychiatry, Seoul, Korea The Catholic University of Korea, Seoul St, Mary's Hospital, Department of Ophthalmology and Visual Science, Seoul, Kor Institute of Cancer Research, Cancer Research UK Cancer Imaging Centre, Division of Radiotherapy and Imaging, London, UK Nencki Institute of Experimental Biology of Polish Academy of Sciences, Neurobiology Center, Laboratory of Molecular Neurobiology, Warsaw, Poland University of Chile, Institute of Nutrition and Food Technology (INTA), Advanced Center for Chronic Diseases (ACCDiS), Santiago, Chile University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatrics, Cologne, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Center for Molecular Medicine (CMMC), Cologne, Germany University of Rome “La Sapienza”, Rome, Italy University of Liverpool, Institute of Translational Research, Cellular and Molecular Physiology, Liverpool, UK Molecular Physiology and Cell Signaling, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK Università di Milano, Department of Biomedical and Clinical Sciences L. Sacco, Milan, Italy Istituto Superiore di Sanità, Department of Infectious Diseases, Rome, Italy Institut Necker-Enfants Malades (INEM), INSERM U1151/CNRS UMR 8253, Université de Paris, Paris, France The Hebrew University of Jerusalem, The Institute for Medical Research Israel-Canada, Department of Biochemistry and Molecular Biology, Ein Karem, Jerusalem, Israel University Roma Tre, Department of Science, LIME, Rome, Italy National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Pediatric Translational Research Branch, Bethesda, MD, USA Institut d'Investigacions Biomèdiques de Barcelona (CSIC, IDIBAPS), and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain University of Belgrade, Institute for the Application of Nuclear Energy (INEP), Belgrade, Serbia Centre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Campus UAB, Bellaterra, Barcelona, Spain University of Sheffield, Department of Biomedical Science, Firth Court, Western Bank, Sheffield, UK Instituto de Histología y Embriología (IHEM)-Universidad Nacional de Cuyo-CONICET, Facultad de Ciencias Médicas, Mendoza, Argentina Yale University School of Medicine, Department of Neuroscience and Department of Cell Biology, New Haven, CT, USA Clermont-Auvergne University, INRAE, Human Nutrition Unit, F-63000, Clermont-Ferrand, France University of Pavia, Department of Biology and Biotechnology “L. Spallanzani”, Pavia, Italy Federal University of São Carlos, Department of Gerontology, São Carlos, SP, Brazil Department of Pathology and Experimental Therapeutics and Institute of Biomedicine of the University of Barcelona (IBUB), Bellvitge University Hospital-IDIBELL, Hospitalet de Llobregat; University of Brescia, Department of Molecular and Translational Medicine, Brescia BS, Italy National Institutes of Health, NIAMS, Lymphocyte Nuclear Biology, Bethesda, MD, USA Rutgers University, Department of Biological Sciences, Newark, NJ, USA National Institutes of Health, National Institute on Aging, Laboratory of Neurogenetics, Bethesda, MD, USA University of Manitoba, Department of Medical Microbiology & Infectious Diseases, Winnipeg, Manitoba, Canada Johns Hopkins University, Department of Molecular Microbiology and Immunology, Baltimore, MD, USA University Magna Graecia of Catanzaro, Department of Health Sciences, Catanzaro, Italy Umeå University, Umeå Centre for Microbial Research (UCMR), Department of Chemistry, Umeå, Sweden OncoRay National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany; Helmholtz-Zentrum Dresden - Rossendorf, Institute of Radiooncology - OncoRay, Dresden, Germany; German Cancer Consortium (DKTK), Partner site Dresden, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany OncoRay National Center for Radiation Research in Oncology, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany University of Genoa, DIMES Department of Experimental Medicine, Human Anatomy, Genoa, Italy University of Michigan Medical School, Department of Neurology, Ann Arbor, MI, USA University of Zürich, Schlieren Campus, Center for Molecular Cardiology, Schlieren, Switzerland University of Oviedo, Department of Morphology and Cell Biology, Oviedo, Spain University of Melbourne, Department of Pharmacology and Therapeutics, Melbourne, Victoria, Australia CSIC-Universidad de Sevilla, Instituto de Bioquímica Vegetal y Fotosíntesis, Sevilla, Spain Universidad de Chile, Facultad de Odontología, Advanced Center for Chronic Diseases, Santiago, Chile Università degli Studi di Milano, Dipartimento di Scienze Farmacologiche e Biomolecolari, Centro di Eccellenza per lo studio delle Malattie Neurodegenerative, Milano, Italy Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest, Hungary Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Investigación Sanitaria La Paz (IdiPaz), Instituto de Investigaciones Biomédicas Alberto Sols UAM-CSIC, Madrid, Spain; Universidad Autónoma de Madrid, School of Medicine, Department of Biochemistry, Madrid, Spain Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Materia Medica, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Molecular Immunology and Cancer Pharmacology Group, Beijing, China Sun Yat-sen University, School of Life Sciences, MOE Key Laboratory of Gene Function and Regulation, Guangzhou, Guangdong, China Medical Research Institute, Wuhan University, Wuhan, China The Chinese University of Hong Kong, School of Life Sciences, Centre for Cell & Developmental Biology and State Key Laboratory of Agrobiotechnology, Shatin, New Territories, Hong Kong, China Université Paris-Saclay, CEA, 1035 CNRS, Institute for Integrative Biology of the Cell (I2BC), INSERM U1280, Gif-sur-Yvette, France University of Mar del Plata, Department of Biology and Chemestry, Mar del Plata, BA, Argentina McGill University Health Centre, Montréal, QC, Canada Emory University School of Medicine, Department of Medicine, Atlanta, GA, USA Medical University of Lublin, Department of Pathophysiology, Lublin, Poland University of Bologna, Department of Medical and Surgical Sciences; Rizzoli Orthopaedics Institute, Laboratory of Immunorheumatology and Tissue Regeneration, Bologna, Italy University Campus Bio-Medico, Department of Medicine, Rome, Italy Istituto Dermopatico dell'Immacolata, IDI-IRCCS, Rome, Italy University of Florida, Department of Physical Therapy, Gainesville, FL, USA University “G. D'Annunzio”, Department of Medical Sciences DSMOB, Chieti, Italy; Regina Elena National Cancer Institute, Department of Research, Rome, Italy Federal University of Sergipe, Department of Pharmacy, São José, SE, Brazil University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatrics, Cologne, Germany University of Nevada, Reno School of Medicine, Department of Pharmacology, Reno, NV, USA Gregor Mendel Institute, Vienna Biocenter, Vienna, Austria University of Naples Federico II, Department of Pharmacy, Naples, Italy Xi'an Jiaotong University, Department of Public Health, Xi'an, Shaanxi, China The First Hospital of Jilin University, Laboratory of Cancer Precision Medicine, Changchun, Jilin, China Model Animal Research Center of Nanjing University, Nanjing, Jiangsu, China University of Salerno, Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, Baronissi, SA, Italy University of Padova, Department of Biology, Padova, Italy Research Center Borstel, Cellular Microbiology, Borstel, Germany University of Clermont Auvergne, M2iSH (Microbes, Intestine, Inflammation and Susceptibility of the Host), UMR 1071 Inserm, INRA USC 2018, CRNH, Clermont-Ferrand, France Christian-Albrechts-University Kiel, Biochemical Institute, Kiel, Germany Karolinska Institutet, Biomedicum, Department of Cell and Molecular Biology, Stockholm, Sweden University of South Florida, Morsani College of Medicine, Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Tampa, FL, USA; Institute for Biological Instrumentation of Russian Academy of Sciences, Laboratory of New Methods in Biology, Pushchino, Moscow region, Russia University of South Florida, Morsani College of Medicine, Department of Molecular Medicine, Tampa, FL, USA Texas Tech University Health Sciences Center, Department of Pharmaceutical Sciences, Amarillo, TX, USA Cleveland Clinic, Department of Gastroenterology, Hepatology and Nutrition, Cleveland, OH, USA MD Anderson Cancer Center, Department of Gynecologic Oncology and Reproductive Medicine, Houston, TX, USA Tulane University Health Sciences Center, Department of Pathology and Laboratory Medicine, New Orleans, LA, USA Max-Delbrück-Center for Molecular Medicine, Department of Crystallography, Berlin, Germany Institute of Life Sciences, School of Medicine, Swansea University, Swansea, Wales, UK University of Massachusetts Medical School, Program in Molecular Medicine, Worcester, MA, USA Stellenbosch University, Department of Physiological Sciences, Stellenbosch, Western Cape, South Africa University of Dundee School of Medicine, Division of Cellular Medicine, Dundee, Scotland, UK University of Calabria, Department of Farmacy Health and Nutritional Sciences, Rende, Italy Ghent University, Translational Nuclear Receptor Research, VIB Center for Medical Biotechnology, Department of Biomolecular Medicine, Ghent, Belgium “Sapienza” University of Rome, Department of Radiotherapy, Policlinico Umberto I, Rome, Italy University of Verona, Azienda Ospedaliera Universitaria Integrata-Verona, Department of Medicine, Verona; Italy Oswaldo Cruz Foundation, Oswaldo Cruz Institute, Leprosy Laboratory, Rio de Janeiro, Brazil University of Antwerp, Laboratory of Physiopharmacology, Antwerp, Belgium Department of Oncology-Pathology, Cancer Center Karolinska, Karolinska Institute, Stockholm, Sweden. Sapienza University of Rome, Ospedale Sant'Andrea, Rome, Italy Università degli Studi di Milano, Department of Medical Biotechnology and Translational Medicine, Milano, Italy University of Urbino Carlo Bo, Department of Biomolecular Sciences, Unit of Pharmacology and Public Health, Urbino, Italy University of Fribourg, Department of Biology, Fribourg, Switzerland Danish Cancer Society Research Center, Cell Stress and Survival Unit, Center for Autophagy, Recycling and Disease (CARD), Copenhagen, Denmark University of California, San Francisco, Department of Pathology, San Francisco, CA, USA Washington University School of Medicine, Departments of Pediatrics and Cell Biology & Physiology, St. Louis, MO, USA KU Leuven, Department of Development and Regenaration, Laboratory of Pediatrics, PKD Research Group, Leuven, Belgium Boston University, Department of Biology, Boston, MA, USA IFOM, The FIRC Institute of Molecular Oncology, Milan, Italy University of Colorado Anschutz Medical Campus, Department of Biochemistry and Molecular Genetics, Aurora, CO, USA University of Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France Instituto de Fisiologia Celular, UNAM, Department of Biochemistry and Structural Biology, Mexico City, Mexico Medical University of South Carolina, Charleston, SC 29425, USA University of Melbourne, School of Biomedical Sciences, Melbourne, Victoria, Australia University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Institute of Immunology, Genetics and Metabolism (INIGEM), CONICET. Buenos Aires, Argentina L.N.C.I.B. Laboratorio Nazionale Consorzio Interuniversitario Biotecnologie, AREA Science Park, Trieste, Italy University of Zagreb School of Medicine, Department of Physiology and Croatian Institute for Brain Research, Zagreb, Croatia Hospital for Sick Children, Program in Cell Biology Department, Toronto, Canada; University of Toronto, Department of Biochemistry, Toronto, Canada Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Medicinal Biotechnology, Beijing, China Virginia Commonwealth University, Department of Biochemistry and Molecular Biology, Richmond, VA, USA Centre for Cancer Biology, University of South Australia, Adelaide, Australia Division of Developmental Biology, National Institute of Child Health & Human Development, National Institutes of Health, Bethesda, MD, USA. University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA University of New Mexico Health Sciences Center, Autophagy, Inflamamtion and Metabolism (AIM) Center, Albuquerque, NM, USA Institut National de la Recherche Scientifique, Centre Armand-Frappier Santé Biotechnologie, Laval, QC, Canada Bellvitge Biomedical Research Institute-IDIBELL, Oncobell Program. L'Hospitalet de Llobregat, Barcelona, Spain University of California, San Diego; Section of Cell and Developmental Biology, La Jolla, CA, USA University of Zurich, Institute of Physiology, Zurich, Switzerland Walter and Eliza Hall Institute of Medical Research, Ubiquitin Signalling Division, Melbourne, Australia; University of Melbourne, Department of Medical Biology, Melbourne, Australia University of Naples “Federico II”, Department of Chemical, Materials and Industrial Production Engineering, Naples, Italy University of Perugia, Department of Chemistry, Biology and Biotechnology, Perugia, Italy Sapienza University of Rome, Department of Biochemical Sciences A. Rossi Fanelli, Rome, Italy Philipps University of Marburg, Department of Visceral, Thoracic and Vascular Surgery, Marburg, Germany IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Dino Ferrari Center, Neuroscience Section, University of Milan, Department of Pathophysiology and Transplantation, Milan, Italy University of Teramo, Faculty of Veterinary Medicine, Teramo, Italy Western University, Department of Physiology and Pharmacology, London, ON, Canada Harvard Medical School, Boston Children’s Hospital, F.M. Kirby Neurobiology Center, Translational Neuroscience Center, Department of Neurology, Boston, MA, USA National Institute for Infectious Diseases “L. Spallanzani” IRCCS, Rome, Italy National and Kapodistrian University of Athens, Department of Biology, Panepistimioupolis, Athens, Greece University of Cincinnati College of Medicine, Department of Cancer Biology, Cincinnati, OH, USA University of Chile, Faculty of Chemical and Pharmaceutical Sciences, Department of Chemical Pharmacology and Toxicology, Santiago de Chile, Chile University of Alcalá, Deparment of Systems Biology, Biochemistry and Molecular Biology, Alcalá de Henares, Madrid, Spain Arizona State University, Phoenix, AZ, USA Seoul National University, College of Pharmacy, Seoul, Korea University of Montreal, Faculty of Medicine, Microbiology, Infectious diseases and Immunology Department, CRCHUM, Montréal, QC, Canada Goethe University, Institute of Biochemistry II, Faculty of Medicine, Frankfurt am Main, Germany Zhejiang University, School of Medicine, Department of Cell Biology, Hangzhou, Zhejiang Province, China University of Kansas Medical Center, Department of Pharmacology, Toxicology and Therapeutics, Kansas City, KS, USA University of Rome La Sapienza, Department of Biology and Biotechnology C. Darwin, Rome, Italy University of Belgrade, Institute for Biological Research “Sinisa Stankovic” - National Institute of Republic of Serbia, Department of Neurobiology, Belgrade, Serbia University of Belgrade, Institute of Molecular Genetics and Genetic Engineering, Belgrade, Serbia Johns Hopkins University School of Medicine, Department of Pharmacology and Molecular Sciences and Department of Medicine, Baltimore, MD, USA Imperial College London, Department of Life Sciences and MRC Centre for Molecular Bacteriology and Infection, London, UK Friedrich-Alexander University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology, Erlangen, Germany Washington University School of Medicine and John Cochran VA Medical Center, Department of Medicine, St. Louis, MO, USA University of Manitoba, Institute of Cardiovascular Sciences, Department of Physiology and Pathophysiology, Winnipeg, Manitoba, Canada Centre de Recherche des Cordeliers, INSERM UMRS 1138, Sorbonne Université, Université de Paris, Equipe 11 labellisée par la Ligue contre le Cancer, 75006 Paris, France; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, 94805 Villejuif, France University of Calgary, Department of Comparative Biology and Experimental Medicine, Calgary, AB, Canada University of Colima, University Center for Biomedical Research, Colima, Mexico. University of Canterbury, Biomolecular Interaction Centre, School of Biological Sciences, Christchurch, New Zealand Hacettepe University, Faculty of Medicine, Department of Medical Biology, Ankara, Turkey University of Kentucky, College of Medicine, Markey Cancer Center, Lexington, KY, USA University of Texas Southwestern Medical Center, Department of Internal Medicine, Center for Autophagy Research, Dallas, TX, USA Jinshan Branch of Shanghai Sixth People's Hospital, Department of Laboratory Medicine, Shanghai, China Washington University in St Louis School of Medicine, Department of Internal Medicine, St. Louis, MO, USA Goethe University, Institute of Biophysical Chemistry, Frankfurt, Germany Nanjing University, Medical School, Division of Immunology, Nanjing, Jiangsu, China Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, USA Umeå University, Department of Chemistry, Umeå, Sweden University of Arkansas, Center of Excellence for Poultry Science, Fayetteville, AR, USA Oncogenetic Laboratory, Meir Medical Center, Kfar Saba, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Tongren Hospital, Shanghai Jiaotong University School of Medicine, Department of Neurology, Shanghai, China University of British Columbia, Department of Urologic Sciences, Vancouver, BC, Canada National Institute of Biological Sciences, Beijing, China Central South University, The Second Xiangya Hospital, Department of Nephrology, Changsha , Hunan, China Chinese Academy of Medical Sciences and Peking Union Medical College, Institute of Blood Transfusion, Chengdu, China Cardiff University, Division of Cancer and Genetics, Heath Park, Cardiff, UK Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Consejo Superior de Investigaciones Científicas, Universidad de Sevilla, Universidad Pablo de Olavide, Seville, Spain Shanghai Proton and Heavy Ion Center, Department of Research & Development, Pudong, Shanghai, China University Medical Center Hamburg-Eppendorf, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hamburg, Germany A.V. Zhirmunsky National Scientific Center of Marine Biology, Laboratory of Pharmacology, Far Eastern Branch, Russian Academy of Sciences, Vladivostok, Russian Federation Far Eastern Federal University, School of Natural Sciences, Vladivostok, Russian Federation Department of Neurology, Boston Children’s Hospital, Boston, MA, USA Medical University of Vienna, Department of Dermatology, Division for Biology and Pathobiology of the Skin, Vienna, Austria University of Colorado Anschutz Medical Campus, Division of Renal diseases, Aurora, CO, USA University of Manitoba, Department of Physiology and Pathophysiology, Regenerative Medicine Program, Winnipeg, Manitoba, Canada University of Cologne, Centre for Biochemistry, Institute of Biochemistry I, Medical Faculty, Cologne, Germany United Arab Emirates University, College of Medicine & Health Sciences, Department of Anatomy, Al Ain, UAE University of Graz, NAWI Graz, Institute of Molecular Biosciences, Graz, Austria; BioTechMed Graz, Graz, Austria; University of Graz, Field of Excellence BioHealth, Graz, Austria Long Beach VA and University of California, Irvine, Irvine, CA, USA Ain Shams University, Faculty of Medicine, Department of Medical Biochemistry and Molecular Biology, Cairo, Egypt Hospital Universitari de Tarragona Joan XXIII, Institut d’Investigació Santitària Pere Virgili University of Illinois at Chicago, Department of Pathology, College of Medicine, Chicago, IL, USA Florida International University, Department of Immunology and Nano-Medicine, Miami, FL, USA Children’s Cancer Hospital Egypt 57357, Tumor Biology Research Program, Cairo, Egypt University of Camerino, Department of Biosciences and Biotechnology, Camerino, Italy Damietta University, Faculty of Science, Biochemistry Department, Damietta, Egypt Technische Universität Dresden, Medical Clinic I, University Hospital Carl Gustav Carus, Dresden, Germany; Technische Universität Dresden, Faculty of Medicine, Institute for Clinical Chemistry and Laboratory Medicine, Dresden, Germany; Institute of Molecular Genetics of the ASCR, Department of Cancer Cell Biology, Prague, Czech Republic Instituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), Universidad de Buenos Aires-CONICET, Argentina University of Sheffield, The Bateson Centre, Department of Infection, Immunity and Cardiovascular Disease,Sheffield, South Yorkshire, UK Philipps University of Marburg, Department of Cytobiology and Cytopathology, Marburg, Germany Sanford Burnham Prebys Medical Discovery Research Institute, La Jolla, CA, USA Bogazici University, Department of Molecular Biology and Genetics, Bebek, Istanbul, Turkey Pfizer, Oncology Research & Development, Pearl River, NY, USA Oslo University Hospital, Institute for Cancer Research, Department of Tumor Biology, Montebello, Oslo, Norway University of Bergen, Department of Biomedicine/ Centre for Cancer Biomarkers (CCBIO), Bergen, Norway Instituto de Investigaciones Biomédicas Alberto Sols, C.S.I.C./U.A.M., Madrid, Spain Universität zu Köln, CECAD Forschungszentrum, Institut für Genetik, Köln, Germany University of Turku, Institute of Biomedicine, Turku, Finland IRIM, University of Montpellier, CNRS, Montpellier, France Medical University of Lodz, Department of Laboratory Diagnostics, Lodz, Poland Sapienza University of Rome, DAHFMO-Section of Anatomy, Rome, Italy Istituto Superiore di Sanità, Department of Oncology and Molecular Medicine, Rome, Italy Karolinska Institutet, Institute of Environmental Medicine, Stockholm, Sweden Universidad Nacional de Cuyo, Facultad de Ciencias Médicas, Laboratorio de Biología Celular y Molecular, IHEM-CONICET, Mendoza, Argentina Max-Planck-Institute of Biophysical Chemistry, Biochemistry of Signal Dynamics, Göttingen, Germany La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australia; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia; School of Cancer Medicine, La Trobe University, Melbourne, Victoria, Australia Universidad Miguel Hernández (UMH), Instituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), Elche, Spain Dresden University Medical Center, Department of Neurology, Dresden, Germany University of South Carolina School of Medicine, Department of Cell Biology and Anatomy, Columbia, SC, USA University of Pittsburgh, Department of Surgery, Pittsburgh, PA, USA University of Cincinnati, Department of Cancer Biology, Cincinnati, OH, USA University of Oslo and Akershus University Hospital, Department of Clinical Molecular Biology, Lørenskog, Norway; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway Shanghai Institute of Organic Chemistry, Chinese Academy of Science, Interdisciplinary Research Center on Biology and Chemistry, Shanghai, China; University of Chinese Academy of Sciences, Beijing, China The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China King’s College London, Department of Basic and Clinical Neuroscience, London, United Kingdom; Institut du Cerveau et de la Moelle épinière (ICM), Paris, France Centre International de Recherche en Infectiologie (CIRI), University Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS Lyon, Lyon, France Rudolf Virchow Center, University of Würzburg, Würzburg, Germany South Australian Health and Medical Research Institute, Hopwood Centre for Neurobiology, Lifelong Health Theme, Adelaide, South Australia, Australia Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA Guangzhou Medical University, School of Basic Medical Sciences, State Key Laboratory of Respiratory Disease, Guangzhou, China The First Hospital of Jilin University, Department of Neurology, Changchun, China Medical School of Zhejiang University, Sir Run Run Shaw Hospital, Key lab of Biotherapy in Zhejiang, Laboratory of Cancer Biology, Hangzhou, China The University of Hong Kong, School of Chinese Medicine, Li Ka Shing Faculty of Medicine, Hong Kong, China Baylor College of Medicine, Department of Biochemistry and Molecular Biology, Houston TX, USA Chinese Academy of Sciences, Institute of Biophysics, Beijing, China University of São Paulo (USP), Ribeirão Preto Medical School, Department of Genetics, Ribeirão Preto, SP, Brazil. Washington University in St. Louis, Department of Ophthalmology and Visual Sciences, St. Louis, MO, USA University of Texas Southwestern Medical Center, Center for Autophagy Research, Department of Internal Medicine and Howard Hughes Medical Institute, Dallas, TX, USA Institute of Biomedical Research of Barcelona (IIBB)-CSIC, Barcelona, Spain; Liver Unit, Hospital Clinic i Provincial de Barcelona, IDIBAPS and CIBEREHD, Barcelona, Spain; Research Center for ALPD, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA Columbia University, New York, NY, USA Università del Piemonte Orientale, Department of Health Sciences, Laboratory of Molecular Pathology, Novara, Italy University of Sao Paulo, Institute of Biosciences, Sao Paulo, SP, Brazil University of California, San Diego, Department of Cellular and Molecular Medicine, La Jolla, CA, USA Instituto de Investigaciones Marinas CSIC, Department of Biotechnology and Aquaculture, Immunology and Genomics, Vigo, Spain University of Padua, Department of Biomedical Sciences, Padua, Italy; Italian National Research Council (CNR), Neuroscience Institute, Padua, Italy University of Piemonte Orientale, Department of Translational Medicine, Novara, Italy Universidade Federal do Rio Grande do Sul (UFRGS), Morphological Sciences Department, Porto Alegre, RS, Brazil; Clinicas Hospital of Porto Alegre, Porto Alegre, RS, Brazil Danish Cancer Society Research Center, Redox Signaling and Oxidative Stress Group, Copenhagen, Denmark Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy Università degli Studi Sapienza di Roma, SAIMLAL Department, Roma, Italy Center for Systems and Therapeutics, Gladstone Institutes; Departments of Neurology and Physiology, University of California San Francisco, San Francisco, CA, USA NYU School of Medicine, Department of Medicine, New York, NY, USA Virginia Commonwealth University, School of Medicine, Department of Human and Molecular Genetics, Richmond, VA, USA; Virginia Commonwealth University, VCU Institute of Molecular Medicine, Richmond, VA, USA; Columbia University, College of Physicians and Surgeons, Departments of Pathology, Neurosurgery and Urology, New York, NY, USA State University of New York, University at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Departments of Ophthalmology/Biochemistry and Neuroscience Program, Buffalo, NY, USA Norwegian University of Science and Technology, Department of Clinical and Molecular Medicine, Centre for Molecular Inflammation Research, Trondheim, Norway Central University of Tamil Nadu, Thiruvarur, Tamil Nadu, India Babraham Institute, Signalling ISP, Cambridge, UK University of Genova, Department of Internal Medicine and IRCCS Policlinico San Martino, Genova, Italy Montreal Neurological Institute, Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada University of Pavia, Department of Molecular Medicine, Biochemistry Unit, Pavia, Italy University of Pisa, Department of Translational Medicine and New Technologies in Medicine and Surgery, Pisa, Italy; I.R.C.C.S. Neuromed Pozzilli, Pozzilli, Italy Istituto Superiore di Sanità, Department of Environment and Health, Section of Mechanisms, Biomarkers and Models, Rome, Italy University of Texas Medical Branch, Mitchell Center for Neurodegenerative Diseases, Department of Neurology, Galveston, TX, USA University of Nebraska-Lincoln, Redox Biology Center, Lincoln, NE, USA Laboratory of Sex-gender Medicine, National Institute of Biostructures and Biosystems, Sassari, Italy Icahn School of Medicine at Mount Sinai, Department of Medicine, Division of Liver Diseases, New York, NY, USA Institute of Science and Technology Austria (IST), Klosterneuburg, Austria Clínica Universidad de Navarra, Metabolic Research Laboratory, CIBEROBN, IdiSNA, Pamplona, Spain University of Extremadura, Centro de Investigación Biomedica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Investigación Biosanitaria de Extremadura (INUBE), Department of Biochemistry, Molecular Biology and Genetics, Faculty of Nursing and Occupational Therapy, Cáceres, Spain Kyushu University, Medical Institute of Bioregulation, Fukuoka, Japan Tokyo Institute of Technology, Institute of Innovative Research, Cell Biology Center, Yokohama, Japan National Institute of Neuroscience, National Center of Neurology and Psychiatry, Department of Degenerative Neurological Diseases, Kodaira, Tokyo, Japan Tohoku University, Graduate School of Life Sciences, Department of Integrative Life Sciences, Sendai, Miyagi, Japan Goethe-University Frankfurt, Institute for Experimental Cancer Research in Pediatrics, Frankfurt, Germany Monash University, Cancer Program, Biomedicine Discovery Institute and Department of Anatomy & Developmental Biology, VIC, Australia; Peter MacCallum Cancer Centre, Prostate Cancer Translational Research Laboratory, Melbourne, Victoria, Australia; University of Melbourne, Sir Peter MacCallum Department of Oncology, Parkville, VIC, Australia Juntendo University Graduate School of Medicine, Department of Neurology, Bunkyo-ku, Tokyo Japan The University of Chicago, Department of Microbiology, Chicago, IL, USA University of Gdansk, Department of Molecular Biology, Gdansk, Poland New York University - Abu Dhabi, Saadiyat Island Campus, Division of Science (Biology), Cell Death Signaling Laboratory, Abu Dhabi, UAE University of Oxford, Sir William Dunn School of Pathology, Oxford, UK Universidad Castilla La Mancha, Facultad de Farmacia, Área Tecnología Farmacéutica, Albacete, Spain Beckman Research Institute at City of Hope, Department of Systems Biology, Monrovia, CA, USA Weill Cornell Medical College, Department of Radiation Oncology, New York, NY, USA; Sandra and Edward Meyer Cancer Center, New York, NY, USA; Caryl and Israel Englander Institute for Precision Medicine, New York, NY, USA; Yale School of Medicine, Department of Dermatology, New Haven, CT, USA; Université de Paris, Paris, France Sorbonne Université, Developmental Biology Laboratory, CNRS, Institut de Biologie Paris Seine, IBPS, UMR7622, Paris, France University of Edinburgh, Cancer Research UK Edinburgh Centre, Institute of Genetics and Molecular Medicine, Edinburgh, UK University of Texas MD Anderson Cancer Center, Department of Experimental Radiation Oncology, Houston, TX, USA MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, UK Fourth Military Medical University, School of Aerospace Medicine, Xi'an, China Chinese Academy of Sciences, Institute of Zoology, State Key Laboratory of Stem cell and Reproductive Biology, Beijing, China Harbin Institute of Technology, the HIT Center for Life Sciences, School of Life Sciences and Technology, Harbin, China South China University of Technology, School of Medicine and Institute for Life Sciences, GuangZhou, China University of Pittsburgh School of Medicine, Hillman Cancer Center and Department of Microbiology and Molecular Genetics, Pittsburgh, PA, USA University of Pittsburgh School of Medicine, Department of Surgery, Pittsburgh, PA, USA Chinese Academy of Sciences Center for Excellence in Molecular and Cellular Sciences, Shanghai Institute of Biochemistry and Cell Biology, Shanghai, China Universitat de Lleida, Department of Experimental Medicine, IRBLleida, Lleida, Spain Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Microbiología, Inmunología y Biotecnología, Cátedra de Inmunología, Buenos Aires, Argentina; Universidad de Buenos Aires, CONICET, Instituto de Estudios de la Inmunidad Humoral (IDEHU), Buenos Aires, Argentina Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), Buenos Aires, Argentina National Center for Biotechnology (CNB)-CSIC, Laboratory of Intracellular Bacterial Pathogens, Madrid, Spain Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Anatomía, Histología y Neurociencia, Madrid, Spain Universidad Autonoma de Nuevo Leon, School of Medicine, Department of Histology, Monterrey, Nuevo Leon, Mexico Universidad de Salamanca, Institute of Functional Biology and Genomics (IBFG), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain Department of Cell Biology and Histology, Faculty of Biology, University of Murcia, IMIB-Arrixaca, Murcia, Spain Department of Cell Death and Proliferation, Institute of Biomedical Research of Barcelona (IIBB- CSIC); Liver Unit, Hospital Clinic i Provincial de Barcelona, IDIBAPS, CIBEREHD, Barcelona, Spain Cajal Institute/CSIC and CIBERNED, ISCIII, Madrid, Spain KU Leuven, Department of Cellular and Molecular Medicine, Leuven, Belgium Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain Sapienza University of Rome, Department of Experimental Medicine, Rome, Italy Tulane University, Department of Microbiology and Immunology, New Orleans, LA, USA University of Bonn, Clinical Centre, Department of Psychiatry, Neurohomeostasis Group, Bonn, Germany Zhejiang University School of Medicine,Women's Hospital,Hangzhou, Zhejiang, China University of Milano, Department of Biomedical Sciences for Health, Milan, Italy Institut de Biologie Moléculaire des Plantes, Centre National de la Recherche Scientifique, Unité Propre de Recherche 2357, Conventionné avec l'Université de Strasbourg, Strasbourg, France University Clinic Freiburg, Institute for Microbiology and Hygiene, University of Freiburg - Faculty of Medicine, Freiburg, Germany Mortimer B. Zuckerman Mind Brain and Behavior Institute, Columbia University, New York, NY, USA Institute for Animal Developmental and Molecular Biology, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany Virginia Commonwealth University, Departments of Pharmacology, Toxicology and Medicine and Massey Cancer Center, Richmond, VA, USA Kerman University of Medical Sciences, Institute of Neuropharmacology, Neuroscience Research Center, Kerman, Iran Autophagy Research Center, Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran University of Torino, Department of Molecular Biotechnology and Health Sciences, Torino, Italy KU Leuven, Department of Public Health and Primary Care, Centre Environment & Health, Leuven, Belgium University of Sussex, School of Life Sciences, Department of Biochemistry and Biomedicine, Brighton, UK Sapienza University of Rome, Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Rome, Italy Democritus University of Thrace, Medical School, Department of Pathology, Alexandroupolis, Greece Weill Cornell Medicine, Brain and Mind Research Institute, Burke Neurological Institute, White Plains, NY, USA University of Manitoba, Departments of Biochemistry and Medical Genetics, Winnipeg, Canada Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland Clinic of Neonatology, Department of Women, Mother and Child, University Hospital Center of Vaud (CHUV), Lausanne, Switzerland National Institutes of Health, National Institutes of Neurological Disorders and Stroke (NINDS), Bethesda, MD, USA University of Ferrara, Department of Morphology, Surgery and Experimental Medicine, Ferrara, Italy University of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal; University of Coimbra, Center for Innovative Biomedicine and Biotechnology, Coimbra, Portugal University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, Ontario, Canada University of California, Davis and MIND Institute, School of Veterinary Medicine, Dept. Molecular Biosciences, Davis, CA, USA INSERM, UMR1037 CRCT, Toulouse, France; Université Toulouse III-Paul Sabatier, UMR1037 CRCT, Toulouse, France; CNRS, ERL5294 CRCT, Toulouse, France University of Cologne, Faculty of Medicine and University Hospital Cologne, Institute for Medical Microbiology, Immunology and Hygiene, Cologne, Germany University of Seville, Department of Genetics, Seville, Spain Ludwig Institute for Cancer Research; University of California San Diego, Department of Cellular and Molecular Medicine, La Jolla, CA, USA Medical University of Warsaw, Department of Immunology, Warsaw, Poland University of Auckland, School of Biological Sciences, Auckland, New Zealand Luxembourg Institute of Health, Department of Oncology, NorLux Neuro-Oncology Laboratory, Luxembourg, Luxembourg Center of Toxins, Immune-response and Cell Signaling (CeTICS) and Laboratório Especial de Ciclo Celular (LECC), Instituto Butantan, São Paulo, Brazil University of Groningen, University Medical Center of Groningen, Department of Biomedical Sciences of Cells and Systems, Groningen, The Netherlands Leiden University Medical Center, Department of Cell and Chemical Biology and Oncode Institute, Leiden, The Netherlands Shanghai Jiao Tong University, School of Life Sciences and Biotechnology, Shanghai, China University of León, Institute of Biomedicine (IBIOMED) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), León, Spain University of La Laguna, Institute of Biomedical Technologies, Department of Basic Medical Sciences, La Laguna, Tenerife, Spain University of Alberta, Department of Biochemistry, Edmonton, Alberta, Canada University of Alabama at Birmingham, Department of Optometry and Vision Science, Birmingham, AL, USA The Henry M. Jackson Foundation, Inc. Bethesda, MD, USA Technische Universität München, Klinikum rechts der Isar, Comprehensive Cancer Center München, München, Germany Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Química Biológica Ciencias Exactas y Naturales (IQUIBICEN), Facultad de Ciencias Exactas y Naturales, Departamento de Química Biológica, Laboratorio de Disfunción Celular en Enfermedades Neurodegenerativas y Nanomedicina, Buenos Aires, Argentina BC Cancer, Michael Smith Genome Sciences Centre, Vancouver, BC, Canada Harvard Medical School, Department of Dermatology, Cutaneous Biology Research Center Massachusetts General Hospital, Boston, MA, USA Consejo Superior de Investigaciones Científicas, Instituto de Bioquímica Vegetal y Fotosíntesis (CSIC-IBVF), Sevilla, Spain Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA Tel Aviv University, Sackler Faculty of Medicine and Sagol School of Neuroscience, Department of Human Molecular Genetics and Biochemistry, Tel Aviv, Israel Max Planck Institute for Biology of Ageing, Cologne, Germany; University of Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany Jena University Hospital, Department of Anesthesiology and Intensive Care Medicine, Center for Molecular Biomedicine (CMB) and Center for Sepsis Control and Care (CSCC), Jena, Germany Weill Cornell Medicine, Feil Family Brain and Mind Research Institute, New York, NY, USA University of Texas MD Anderson Cancer Center, Department of Cancer Systems Imaging, Houston, TX, USA University of the West of England, Department of Applied Sciences, Bristol, UK Flinders University, College of Medicine and Public Health, Adelaide, Australia University of Alabama at Birmingham,Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, Birmingham, AL, USA Boston University, Departments of Biomedical Engineering, Chemistry, and Medicine, Boston, MA, USA Université de Strasbourg/CNRS UPR 3572 Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France University of Iowa, Departments of Pediatrics and Microbiology, Iowa City, IA, USA Max Planck Institute for Biology of Ageing, Cologne, Germany German Institute of Human Nutrition, Department of Molecular Toxicology, Nuthetal, Germany Lanzhou University, School of Public Health, Lanzhou, Gansu, China Case Western Reserve University, Comprehensive Cancer Center, Cleveland, OH, USA University of Salento, Department of Biological and Environmental Sciences and Technologies, Lecce, Italy Research Center Principe Felipe, Cellular Pathology Laboratory, Valencia, Spain Johns Hopkins University School of Medicine, Department of Neuroscience, Baltimore, MD, USA School of Pharmacy, Complutense University, Madrid, Spain; Centro de Investigación Biomédica en Red (CIBER) de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain Dalhousie University, Faculty of Medicine, Departments of Pathology, Biology, and Microbiology & Immunology, Halifax, NS, Canada David Geffen School of Medicine at UCLA, Department of Medicine, Los Angeles, CA, USA KU Leuven, Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, Leuven, Belgium Justus-Liebig University, Department of Internal Medicine, Giessen, Germany Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME, USA Tongji University School of Medicine, Shanghai Tenth People’s Hospital, Department of Gastroenterology, Shanghai, China The University of Sheffield, Department of Biomedical Science, Firth Court, Western Bank, Sheffield, UK University of Virginia, School of Medicine, Department of Surgery, Charlottesville, VA, USA University of California, Los Angeles, Department of Neurology, Molecular and Medical Pharmacology, David Geffen School of Medicine, Los Angeles, CA, USA Institute of Microbial Technology, Department of Molecular Biology, Chandigarh, India CSIR-Central Drug Research Institute, Lucknow, India University of Oslo, Institute of Basic Medical Sciences, Oslo, Norway Deakin University, School of Medicine, Faculty of Health, Victoria, Australia Macquarie University, Faculty of Medicine, Health and Human Sciences, New South Wales, Australia University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences, La Jolla, CA, USA Medical College of Wisconsin, Department of Medicine and Cardiovascular Center, Milwaukee, WI, USA ICAR-Indian Veterinary Research Institute, FMD VP Laboratory, Bengaluru, India University of Eastern Finland, A.I. Virtanen Institute for Molecular Sciences, Kuopio, Finland Brandeis University, Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Waltham, MA, USA University of Gdansk, Department of Medical Biology and Genetics, Gdansk, Poland Tokai University School of Medicine, Department of Molecular Life Sciences, Isehara, Kanagawa, Japan Swedish Agricultural University (SLU), Department of Plant Biology, Uppsala, Sweden Hasselt University, Biomedical Research Institute, Diepenbeek, Belgium University of Surrey, School of Bioscience and Medicine, Department of Microbial Sciences, Stag Hill Campus, Guildford, Surrey, UK Barts Cancer Institute, Queen Mary University of London, Centre for Biotherapeutics and Biomarkers, London, UK Johns Hopkins University Bloomberg School of Public Health, W. Harry Feinstone Department of Molecular Microbiology and Immunology, Baltimore, MD, USA Goethe University, Institute for Molecular Biosciences, Frankfurt/Main, Germany Osaka University, Graduate School of Medicine, Department of Genetics, Suita, Osaka, Japan Zhejiang University, Sir Run Run Shaw Hospital, College of Medicine, Department of Medical Oncology, Zhejiang, Hangzhou, China Sanford Burnham Prebys Medical Discovery Institute, Program of Development, Aging and Regeneration, La Jolla, CA, USA University of Michigan, Department of Biological Chemistry, Ann Arbor, MI, USA Third Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan Department of Neurophysiology, Institute for Biological Research “Siniša Stanković” – National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia University of California, Davis, School of Medicine, Department of Pharmacology, Davis, CA, USA University of Toronto, Department of Medicine, Toronto, Ontario, Canada Monash University, School of Clinical Sciences at Monash Health, Centre for Inflammatory Diseases, Rheumatology Group, Clayton, Victoria, Australia Tohoku University Graduate School of Medicine, Division of Neurology, Department of Neuroscience & Sensory Organs, Sendai, Japan University of Malaya, Institute of Biological Sciences (Genetics), Kuala Lumpur, Malaysia Washington University School of Medicine, Division of Pulmonary and Critical Care Medicine, St. Louis, MO, USA. Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Department of Molecular Pharmacology and Cell Biology, Berlin, Germany California Institute of Technology, Division of Biology and Biological Engineering, Pasadena, CA, USA University of Massachusetts Medical School, Molecular, Cell and Cancer Biology, Worcester, MA, USA Bulgarian Academy of Sciences, Institute of Biology and Immunology of Reproduction Acad. Kiril Bratanov, Sofia, Bulgaria University of Minnesota, Department of Genetics, Cell Biology and Development, Minneapolis, MN, USA Northwestern University, Feinberg School of Medicine, Department of Cell and Developmental Biology, Chicago, IL, USA Sichuan University, West China School of Pharmacy, Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Chengdu, China Jinan University, College of Pharmacy, Guangzhou, China Department of Immunology, Duke University Medical Center, Durham, NC, USA University of Chicago, Department of Medicine, Section of Dermatology, Chicago, IL, USA D'Youville College, School of Pharmacy, Department of Pharmaceutical, Social and Administrative Sciences, Buffalo, NY, USA University of Innsbruck, Institute of Biochemistry and Center for Molecular Biosciences Innsbruck, Innsbruck, Austria; University Medical Center Groningen, University of Groningen, Section Systems Medicine of Metabolism and Signaling, Laboratory of Pediatrics, Groningen, The Netherlands National Institutes of Health, National Eye Institute, Ophthalmic Genetics and Visual Function Branch, Ophthalmic Molecular Genetics Section, Bethesda, MD, USA University of Glasgow, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, Glasgow, UK University College London, Cancer Institute, London, UK Universidade Federal de São Carlos, Department of Genetics and Evolution, São Carlos (SP), Brazil Instituto de Investigación Sanitaria de Navarra (IdISNA), Fundación Miguel Servet, Biomedical Research Center of Navarre-Navarrabiomed, Immunomodulation Group, Pamplona, Spain Université de Bordeaux, Institut des Maladies Neurodégénératives (IMN), CNRS UMR 5293, Bordeaux, France University of Barcelona, Barcelona Hepatic Hemodynamic Unit, Liver Unit, Hospital Clinic, Hospital Clínic-Institut d’Investigacions Biomèdiques (IDIBAPS), Centro de Investigación Biomédica Red de enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain INRA, UR1037 Laboratory of Fish Physiology and Genomics, Campus de Beaulieu, Rennes, France; Hunan Normal University, College of Life Sciences, State Key Laboratory of Developmental Biology of Freshwater Fish, Changsha, Hunan, China University of Lleida, Department of Basic Medical Sciences, IRBLleida, Lleida, Spain Universidad del País Vasco, Instituto Biofisika (CSIC, UPV/EHU) and Departamento de Bioquímica y Biología Molecular, Bilbao, Spain Centenary Institute, The University of Sydney, Newtown, New South Wales, Australia; Faculty of Medicine and Health, The University of Sydney, Newtown, New South Wales, Australia University of Chile, Biomedical Neuroscience Institute, Faculty of Medicine, Santiago, Chile; FONDAP Center for Geroscience Brain Health and Metabolism, Santiago, Chile; University of Chile, Institute of Biomedical Science, Program of Cellular and Molecular Biology, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, USA University of Bern, Institute of Cell Biology, Bern, Switzerland Kyushu University, Depatment of Bioscience and Biotechnology, Nishi-ku, Fukuoka, Japan UT Southwestern Medical Center, Departments of Medicine (Cardiology) and Molecular Biology, Dallas, TX, USA Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM, USA University of Waterloo, School of Pharmacy, Kitchener, ON, Canada University of Hong Kong, Department of Medicine, Division of Neurology, Pokfulam, Hong Kong, China National University of Singapore, Department of Physiology, Singapore University of North Carolina at Chapel Hill, Department of Pharmacology, Chapel Hill, NC, USA Yale University, Department of Molecular Biophysics and Biochemistry, New Haven, CT, USA Swedish University of Agricultural Sciences (SLU) and Linnean Center for Plant Biology, Uppsala BioCenter, Department of Plant Biology, Uppsala, Sweden University Côte d'Azur, FHU OncoAge, Department of Pathology, Nice, France German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Department of Molecular Toxicology, Nuthetal, Germany University of Helsinki, Medicum, Biochemistry and Developmental Biology, Helsinki, Finland University of Birmingham, College of Medical and Dental Sciences, Institute of Inflammation and Ageing, Birmingham, UK Kyungpook National University, School of Medicine, Department of Physiology, Daegu, Korea Kaohsiung Medical University, Graduate Institute of Medicine & Department of Biochemistry, Faculty of Medicine, College of Medicine, Kaohsiung, Taiwan University of Cologne, Institute for Genetics and CECAD Research Center, Cologne, Germany European Molecular Biology Laboratory, Heidelberg, Germany University of Texas Southwestern Medical Center, Department of Internal Medicine, Dallas, TX, USA Chung Shan Medical University, Institute of Medicine, Taiwan National Chiao-Tung University, Department of Applied Chemistry and Institute of Molecular Science, Hsinchu, Taiwan University of Plymouth, Faculty of Health: Medicine, Dentistry and Human Sciences, Peninsula Dental School, Plymouth, Devon, UK Anhui University of Science and Technology, Department of Medical Immunology, Huainan, China Soochow University, Institute of Neuroscience, Suzhou, Jiangsu Province, China University of Texas Southwestern Medical Center, Department of Internal Medicine, Charles and Jane Center for Mineral Metabolism and Clinical Research, Dallas, TX, USA Southern Medical University, Shenzhen Hospital, Department of Gastroenterology, Shenzhen, Guangdong National Tsing Hua University, Department of Chemical Engineering, and Frontier Research Center on Fundamental and Applied Sciences of Matters, Hsinchu, Taiwan Northwest A&F University, College of Veterinary Medicine, Shaanxi Centre of Stem Cells Engineering & Technology, Yangling, Shaanxi, China Shanghai Jiao Tong University School of Medicine, Shanghai General Hospital, Department of Orthopedics, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China State University of New York, Downstate Health Sciences University, Department of Surgery and Cell Biology, Brooklyn, NY, USA Sichuan University, and Collaborative Innovation Center for Biotherapy, West China Hospital, West China School of Basic Medical Sciences & Forensic Medicine, and State Key Laboratory of Biotherapy and Cancer Center, Chengdu, China New York University School of Medicine, Department of Environmental Medicine, Urology, Biochemistry and Molecular Pharmacology, New York, NY, USA Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Immunology & Department of Immunology and Microbiology, Shanghai, China University of Sydney, Kolling Institute, Renal Research Lab, Sydney, New South Wales, Australia Wenzhou Medical University, School of Laboratory Medicine and Life Sciences, Wenzhou, Zhejiang Province, China Huazhong University of Science and Technology, Tongji Medical College, School of Pharmacy, Wuhan, Hubei, China Chongqing University, School of Medicine, Center for Neurointelligence, Chongqing, China The Second Affiliated Hospital of Xi'an Jiaotong University, Department of Radiation Oncology, Xi'an, Shaan Xi, China Zhejiang University School of Medicine, The First Affiliated Hospital, Zhejiang Provincial Key Laboratory of Pancreatic Disease, Hangzhou, Zhejiang, China III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Medical University of Vienna, Department of Pathology, Vienna, Austria University Hospital Jena, Institute of Human Genetics, Jena, Thuringia, Germany University of Otago, School of Biomedical Sciences and Brain Health Research Centre, Department of Biochemistry, Dunedin, New Zealand University of Bern, Institute of Pathology, Bern, Switzerland; TRANSAUTOPHAGY: European network for multidisciplinary research and translation of autophagy knowledge, COST Action CA15138 Max Planck Institute of Biophysics, Department of Theoretical Biophysics, Frankfurt am Main, Germany University of California, Berkeley, Department of Molecular and Cell Biology, Berkeley, CA, USA West Virginia University, School of Medicine, Department of Physiology and Pharmacology, Morgantown, WV, USA Durham University, Department of Biosciences, Durham, UK University of Indonesia, Faculty of Medicine, Department of Obstetric and Gynecology, Jakarta, Indonesia Yonsei University, Department of Biotechnology, Seodaemun-gu, Seoul, Korea The University of Chicago, Department of Pathology, Chicago, IL, USA; present address: VIR Biotechnology, San Francisco, CA, USA University of Messina, Department of Human Pathology in Adult and Developmental Age “Gaetano Barresi”, Section of Pathology, Messina, Italy Kyushu University, Medical Institute of Bioregulation (MIB), Fukuoka, Japan Osaka International Cancer Institute, Department of Molecular and Cellular Biology, Osaka, Japan Juntendo University Graduate School of Medicine, Department of Research for Parkinson's Disease, Tokyo, Japan University of Modena and Reggio Emilia, Department of Life Sciences, Modena, Italy Juntendo University, Juntendo University Graduate School of Medicine, Division for Development of Autophagy Modulating Drugs, Tokyo, Japan University of North Texas Health Science Center, North Texas Eye Research Institute and Department of Pharmaceutical Sciences, Fort Worth, TX, USA University of Michigan, Life Sciences Institute, Department of Molecular and Integrative Physiology, Ann Arbor, MI, USA Centre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, Marseille, France University of Massachusetts Medical School, Department of Microbiology and Physiological Systems, Worcester, MA, USA National University of Córdoba, Clinical Biochemistry Department, CIBICI-CONICET, Córdoba, Argentina Stanford University School of Medicine, Department of Pathology, Stanford, CA, USA Akita University Graduate School of Medicine, Department of Ophthalmology, Akita, Japan Vascular Biology Center, Medical College of Georgia, Augusta University, Augusta, GA, USA; South China University of Technology, Guangzhou First People's Hospital, School of Medicine and Institutes for Life Sciences, Guangzhou, Guangdong, China University of Copenhagen, Copenhagen Biocentre, Faculty of Health and Medical Sciences, Biotech Research & Innovation Centre (BRIC), Neuroinflammation Unit, Copenhagen N, Denmark Chiba University, Department of Biology, Chiba, Japan Keio University School of Medicine, Department of Neurology, Tokyo, Japan University College London, Department of Neuroscience, Physiology and Pharmacology, London, UK Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain; Universitat de Barcelona, Departament de Bioquímica I Biomedicina Molecular, Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain Barcelona Institute of Science and Technology (BIST), Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain; CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain; Universitat de Barcelona, Facultat de Biologia, Departament de Bioquimica i Biomedicina Molecular, Barcelona, Spain Hampton University, School of Pharmacy, Department of Pharmaceutical Sciences, Hampton, VA, USA Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Madrid, Spain; Department of Cell Biology and Immunology, Campus de Cantoblanco, Madrid, Spain RIKEN, Center for Sustainable Resource Science, Wako, Saitama, Japan Danish Cancer Society Research Center, Center for Autophagy, Recycling and Disease, Cell Death and Metabolism Unit, Copenhagen, Denmark; University of Copenhagen, Department of Cellular and Molecular Medicine, Copenhagen, Denmark University of Technology, Department of applied science, Division of Biotechnology, Baghdad, Iraq University of Maryland School of Medicine, Department of Microbiology and Immunology, Baltimore, MD, USA Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Unidad de Bioquimica, Mexico City, Mexico University of Warwick, School of Life Sciences, Coventry, UK Université Paris-Saclay, INSERM ,UMR-S 1193, Châtenay-Malabry, France Lewis Katz School of Medicine at Temple University, Center for Translational Medicine, Philadelphia, PA, USA Houston Methodist Research Institute, Weill-Cornell Medicine, Houston, TX, USA Delft University of Technology, Kavli Institute of Nanoscience, Department of Bionanoscience, Delft, The Netherlands Lund University, Department of Experimental Medical Science, Laboratory of Molecular Neurogenetics, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund, Sweden Luxembourg Institute of Health, Tumor Immunotherapy and Microenvironment (TIME) group, Department of Oncology, Luxembourg City, Luxembourg Cancer Drug Resistance and Stem Cell Program, University of Sydney, NSW, Australia University Hospital of Regensburg, Institute of Clinical Microbiology and Hygiene, Regensburg , Germany Polish Academy of Sciences, Mossakowski Medical Research Centre, Laboratory of Ischemic and Neurodegenerative Brain Research, Warsaw, Poland Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan Université de Sherbrooke, Département d'immunologie et de biologie cellulaire, Sherbrooke, Québec, Canada UMR7242, CNRS, Université de Strasbourg, Strasbourg, France Institute of Experimental Medicine CAS, Department of Neuroregeneration, Prague, Czech Republic Albert Einstein College of Medicine, Department of Developmental and Molecular Biology and Department of Genetics, New York, NY, USA University of Copenhagen, Department of Nutrition, Exercise and Sports, Section of Molecular Physiology, Copenhagen, Denmark Aarhus University Hospital, Steno Diabetes Center Aarhus, Aarhus, Denmark University of Texas Southwestern Medical Center, Department of Molecular Biology, Dallas, TX, USA The First Affiliated Hospital of Nanjing Medical University, Department of Neurosurgery, Nanjing, Jiangsu, China Shanghai University of Traditional Chinese Medicine, Longhua Hospital, Cancer Institute, Shanghai, China Purdue University, Department of Nutrition Science, West Lafayette, IN, USA Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Solna, Stockholm, Sweden The First Hospital of Jilin University, Department of Ear, Nose and Throat, Changchun, Jilin, China Nanjing Medical University, Nanjing First Hospital, Department of Neurology, Nanjing, China University of Pittsburgh, Department of Pharmacology and Chemical Biology, Pittsburgh, PA, USA King's College London, Institute of Psychiatry, Psychology & Neuroscience, Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK Wonkwang Univesity, Department of Biological Sciences, Iksan, Chunbuk, Korea The First Hospital of Jilin University, Cancer Center, Department of Hematology, Changchun, Jilin, China ZhejiangUniversity, Sir Run Run Shaw Hospital, School of Medicine, Key Lab of Biotherapy in Zhejiang Province, Hangzhou, China Xi'an Jiaotong University, School of Medicine, the First Affiliated Hospital, Department of Nephrology, Xi'an City, Shaanxi Province, China Huazhong University of Science and Technology, Liyuan hospital of Tongji Medical College, Department of Endocrinology, Wuhan, Hubei, China Chungnam National University School of Medicine, Infection Control Convergence Research Center, Daejeon, Korea Cancer Research Center of Toulouse (CRCT), INSERM U1037, CNRS ERL5294, University of Toulouse, Toulouse, France University of Rochester, Department of Anesthesiology and Perioperative Medicine, Rochester, NY, USA University of Sheffield, Department of Infection, Immunity and Cardiovascular Disease and the Bateson Centre, Sheffield, UK University of Helsinki, Institute of Biotechnology, Cell and Tissue Dynamics Programme and Electron Microscopy Unit, Helsinki, Finland Indian Institute of Science, Centre for BioSystems Science and Engineering, Bangalore, India Radboud University Medical Centre, Department of Internal Medicine, Nijmegen, The Netherlands Universidad Castilla La Mancha, Departmento Ciencias Medicas, Albacete, Spain Fudan University School of Pharmacy, Department of Biological Medicines, Shanghai, China The University of Suwon, Department of Health Science, Hwaseong, Gyeonggi, Korea Stony Brook University, Department of Pathology, Stony Brook, NY, USA Instituto Nacional de Enfermedades Respiratorias Isamel Cosío Villegas, Departamento de Investigación en Microbiología, Ciudad de México, México Gwangju Institute of Science and Technology, School of Life Sciences, Gwangju, South Korea Korea Food Research Institute, Research Group of Natural Material and Metabolism, Jeollabuk-do, Korea Ewha Womans University, Department of Biochemistry, College of Medicine, Seoul, Korea Seoul National University, School of Biological Science, Seoul, Korea Evelina Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, Children's Neuroscience Centre, London, UK; King's College London, Muscle Signalling Section, Randall Division of Cell and Molecular Biophysics, London, UK; King's College London, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), Department of Basic and Clinical Neuroscience, London, UK Memorial Sloan Kettering Cancer Center, New York, NY, USA University of Ulm, Department of Internal Medicine II, Molecular Cardiology, Ulm, Germany University of Eastern Finland and Kuopio University Hospital, Department of Ophthalmology, Kuopio, Finland University Tartu, Department of Pharmacology, Tartu, Estonia University Medical Center Gottingen, Department of Experimental Neurodegeneration, Gottingen, Germany University of Michigan, Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, Ann Arbor, MI, USA University of California, San Francisco UCSF Diabetes Center, Department of Cell and Tissue Biology, San Francisco, CA, USA University of Kansas Medical Center, Department of Microbiology, Molecular Genetics and Immunology, Kansas City, KS, USA Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, India National Research Council of Italy (CNR), Neuroscience Institute, Padua, Italy European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, UK Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland Karolinska Institutet, Department of Oncology-Pathology, Stockholm, Sweden Gifu University Graduate School of Medicine, Department of Cardioligy, Gifu, Japan Shimane University Faculty of Medicine, Internal Medicine 1, Izumo, Shimane, Japan Seoul National University, School of Biological Sciences, Seoul, Korea UT Southwestern Medical Center, Department of Surgery, Dallas, Texas, USA Chungbuk National University, Department of Biology Education, Seowon-Gu, Cheongju, Chungbuk, Korea CAESAR Research Center, Bonn, Germany German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany Niigata University Graduate School of Medical and Dental Sciences, Department of Cellular Physiology, Niigata, Japan St. Jude Children’s Research Hospital, Department of Immunology, Memphis, TN, USA Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, USA Florida Atlantic University, Charles E. Schmidt College of Medicine, Department of Biomedical Science, Boca Raton, FL, USA Semmelweis University, Budapest, Hungary National and Kapodistrian University of Athens, Medical School, Division of Molecular Oncology, Department of Biological Chemistry, Athens, Greece University of Minnesota, Institute for Translational Neuroscience, Department of Neuroscience, Minneapolis, MN, USA Jadavpur University, Department of Life Science and Biotechnology, Kolkata, India University of Otago, Department of Physiology-HeartOtago, Dunedin, Otago, New Zealand Hokkaido University, Department of Rheumatology, Endocrinology and Nephrology, Sapporo, Japan Max Planck Institute for Infection Biology, Berlin, Germany University of Eastern Finland, Faculty of Health Sciences, School of Pharmacy, Kuopio, Finland University of Arkansas for Medical Sciences, Little Rock, AR, USA Doshisha Women's College of Liberal Arts, Faculty of Pharmaceutical Sciences, Kyotanabe, Kyoto, Japan Commonwealth Scientific and Industrial Research Organization (CSIRO), Agriculture and Food, Brisbane, Queensland, Australia Chang Gung University, Department of Biochemistry and Molecular Biology, Taoyuan, Taiwan, Republic of China Flinders University, Flinders Health and Medical Research Institute, Adelaide, Australia Philipps University and University Hospital of Marburg, Department of Neuropathology, Marburg, Germany National Institutes of Health, National Institute of Allergy and Infectious Diseases, Laboratory of Immunoregulation, Bethesda, MD, USA Oregon Health & Science University, Casey Eye Institute, Portland, OR, USA University of Münster, University Hospital, Department of Neurology with Institute of Translational Neurology, Münster, Germany University of Illinois at Urbana-Champaign, Department of Molecular and Integrative Physiology, Urbana, IL, USA Weill Cornell Medicine, Departments of Pediatrics and Cell and Developmental Biology, New York, NY, USA Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers, INSERM U 1138, Paris, France Queen Mary University of London, Barts Cancer Institute, London, UK University College London, MRC Laboratory for Molecular Cell Biology, London, UK Maastricht University Medical Center, GROW School for Oncology, Department of Radiotherapy, Maastricht|, The Netherlands Ben-Gurion University of the Negev, Faculty of Health Sciences, Department of Clinical Biochemistry and Pharmacology, Beer Sheva, Israel University of Sadat City, Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, Sadat City, Egypt Indiana University-Purdue University (IUPUI), Department of Pathology and Laboratory Medicine, Indianapolis, IN, USA University of Eastern Finland, School of Pharmacy, Kuopio, Finland Barkatullah University, Department of Biochemistry & Genetics, Bhopal, India Charité - Universitätsmedizin Berlin, Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Berlin, Germany Columbia University, Vagelos College of Physicians and Surgeons, Department of Pathology and Cell Biology, New York, NY, USA Friedrich-Schiller-University Jena, University Hospital Jena, Institute of Human Genetics, Jena, Germany. Gyeongsang National University School of Medicine, Department of Biochemistry and Convergence Medical Sciences and Institude of Health Sciences, Jinju, Republic of Korea University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics, Minneapolis, MN, USA Kyungpook National University, School of Medicine, Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, Daegu, Korea Daegu Gyeongbuk Institute of Science and Technology (DGIST), Department of Brain and Cognitive Sciences, Daegu, Korea Dankook University, College of Medicine, Department of Pharmacology, Cheonan, Chungnam, Korea Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cell Factory Research Center, Daejeon, Korea; University of Science and Technology, KRIBB School of Biotechnology, Department of Environmental Biotechnology, Daejeon, Korea Dankook University, College of Dentistry, Cheonan, Korea Seoul National University College of Medicine, Department of Biomedical Sciences, and Ophthalmology, Seoul, Korea Konkuk University, Department of Stem Cell and Regenerative Biotechnology, Seoul, Korea Kyung Hee University, Department of Oral Biochemistry and Molecular Biology, School of Dentistry, Seoul, Korea Sookmyung Women's University, Department of Biological Sciences, Seoul, Korea Korea Research Institute of Chemical Technology, Center for Convergent Research of Emerging Virus Infection, Daejeon, Korea Penn State College of Medicine, Department of Cellular and Molecular Physiology, Hershey, PA, USA Weizmann Institute of Science, Department of Molecular Genetics, Rehovot, Israel New York University School of Medicine, Department of Radiation Oncology, Perlmutter Cancer Center, New York, NY, USA National Institute of Biomedical Innovation, Health and Nutrition (NIBIOHN), Center for Rare Disease Research, Ibaraki, Osaka, Japan AstraZeneca, Bioscience, Oncology R&D, Cambridge, UK University College London, Institute of Healthy Ageing, Department of Genetics, Evolution & Environment, London, UK University of Utah, Huntsman Cancer Institute, Salt Lake City, UT, USA; University of Utah School of Medicine, Division of Oncology, Department of Internal Medicine, Salt Lake City, UT, USA Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research London, Sutton, UK St. Boniface Hospital Albrechtsen Research Centre, Departments of Physiology and Pathophysiology, and Pharmacology and Therapeutics, Max Rady College of Medicine; Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada Vavilov Institute of General Genetics RAS, Department of Epigenetics, Moscow, Russia S&J Kishi Research Corporation, Jupiter, FL, USA Nihon Pharmaceutical University, Department of Pharmaceutical and Medical Business Sciences, Bunkyoku, Tokyo, Japan St. Marianna University Graduate School of Medicine, Department of Molecular Neuroscience, Kanagawa, Japan Nagasaki University, Institute of Biomedical Sciences, Department of Clinical Research Pharmacy, Nagasaki, Japan Albert Einstein College of Medicine, Departments of Medicine and Cell Biology and Wilf Family Cardiovascular Research Institute, Bronx, NY, USA University of Copenhagen, Department of Neuroscience, Copenhagen, Denmark Perelman School of Medicine at the University of Pennsylvania, Department of Medicine (Hematology-Oncology), Philadelphia, PA, USA Friedrich-Baur-Institute, Department of Neurology, University of Munich, Munich, Germany University Hospital Erlangen, Department of Molecular Neurology, Erlangen, Germany University of Oslo, Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, Montebello, Norway; Oslo University Hospital, Department of Molecular Cell Biology, Institute for Cancer Research, Montebello, Norway The University of Tokyo, Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Tokyo, Japan The Hong Kong Polytechnic University, Department of Applied Biology and Chemical Technology, Hong Kong, China Icahn School of Medicine at Mount Sinai, Department of Geriatrics and Palliative Medicine, New York, NY, USA The University of Tokyo, Institute for Quantitative Biosciences, Laboratory of RNA Function, Tokyo, Japan; Albert Einstein College of Medicine, Department of Anatomy and Structural Biology, Bronx, NY, USA New York Institute of Technology, College of Osteopathic Medicine, Department of Biomedical Sciences, Old Westbury, NY, USA Johann Wolfgang Goethe-University Frankfurt am Main, Faculty of Computer Science and Mathematics, Institute of Computer Science, Frankfurt am Main, Germany University Medicine Göttingen, Clinic for Neurology, Göttingen, Germany University Hospital Münster (UKM), Institute of Musculoskeletal Medicine, Münster, Germany Goethe University Hospital Frankfurt, Neuroscience Center, Experimental Neurosurgery, Frankfurt/Main, Germany Division of Brain Disease Research, Korea National Institute of Health, Cheongju-si, Republic of Korea Juntendo University Graduate School of Medicine, Department of Cell Biology and Neuroscience, Hongo, Bunkyo-ku, Tokyo, Japan University of Graz, Institute of Molecular Biosciences, BioTechMed-Graz, Graz, Austria Juntendo University School of Medicine, Department of Physiology, Bunkyo-ku, Tokyo, Japan Sapporo Higashi Tokushukai Hospital, Advanced Surgery Center, Sapporo, Hokkaido, Japan The Abigail Wexner Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, Columbus, OH, USA Earlham Institute, Norwich, UK Newcastle University, Ageing Research Laboratories, Institute for Cell and Molecular Biosciences, Newcastle upon Tyne, UK Norwegian University of Science and Technology (NTNU), Department of Biotechnology and Food Science, Trondheim, Norway; Korsnes Biocomputing (KoBio), Trondheim, Norway University of Eastern Finland, Department of Ophthalmology, Kuopio, Finland Indiana University School of Medicine, Indianapolis, IN, USA Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima, Japan China National Rice Research Institute, State Key Laboratory of Rice Biology, Hangzhou. China Democritus University of Thrace, Department of Radiotherapy/Oncology, Alexandroupolis, Greece Kanazawa Medical University, Department of Diabetology & Endocrinology, Uchinadacho, Ishikawa, Japan Fukuoka University, Faculty of Pharmaceutical Sciences, Department of Biochemistry, Fukuoka, Japan University of Freiburg, Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, Freiburg, Germany; University of Freiburg, CIBSS - Centre for Integrative Biological Signalling Studies, Freiburg, Germany Northwestern University Feinberg School of Medicine, Department of Neurology, Chicago, IL, USA University of Texas, Southwestern Medical Center, Dallas, TX, USA Queen's University of Belfast, Wellcome-Wolfson Institute for Experimental Medicine, Belfast, UK Université Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5310, INSERM U1217, Institut NeuroMyoGène, Lyon, France Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Paris, France; Institut Gustave Roussy, Metabolomics and Cell Biology Platforms, Villejuif, France; Hôpital Européen Georges Pompidou, AP-HP, Pôle de Biologie, Paris, France; Chinese Academy of Medical Sciences, Suzhou Institute for Systems Medicine, Suzhou, China; Karolinska Institute, Karolinska University Hospital, Department of Women's and Children's Health,... Babraham Institute, Babraham, Cambridge, UK Tokyo University of Science, Department of Applied Biological Science, Noda, Chiba, Japan VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium; KU Leuven, Department of Neurosciences, Leuven Brain Institute, Leuven, Belgium University of Bonn, LIMES Institute, Bonn, Germany Emory University, Department of Pharmacology and Chemical Biology, School of Medicine, Atlanta, GA, USA PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Jammu, India University of Houston, Department of Pharmacological and Pharmaceutical Sciences, Houston, TX, USA Julius L. Chambers Biomedical/Biotechnology Research Institute (BBRI) and North Carolina Central University, Department of Pharmaceutical Sciences, Durham, NC, USA International Centre for Genetic Engineering and Biotechnology, Cellular Immunology Group, Aruna Asaf Ali Marg, New Delhi, India Shiga University of Medical Science, Department of Medicine, Otsu, Shiga, Japan Kalinga institute of industrial technology (KIIT-DU), School of Biotechnology, Campus 11, Patia, Bhubaneswar, Odisha, India St. Jude Children’s Research Hospital, Department of Pathology, Memphis, TN, USA Indian Institute of Technology (IIT) Guwahati, Department of Biosciences and Bioengineering, Guwahati, Assam, India Virginia Commonwealth University, Department of Computer Science, Richmond, VA, USA University of Colorado Anschutz Medical Campus, Department of Pharmacology, Aurora, CO, USA Sabanci University Nanotechnology Research and Application Center (SUNUM), Tuzla, Istanbul, Turkey Wonkwang University School of Medicine, Zoonosis Research Center, Iksan, Jeonbuk, Korea Keimyung University, School of Medicine, Department of Immunology, Daegu, Korea Protein Metabolism Medical Research Center and Department of Biomedical Sciences, Seoul National University School of Medicine, Seoul, Korea University of California, Irvine School of Medicine, Irvine, CA, USA INRS, INRS-Institut Armand-Frappier. Montréal, QC, Canada University of Burgundy, Centre Georges François Leclerc, Department of Medical Oncology, Dijon, France University of Ferrara, Department of Translational Medicine, Ferrara, Italy Cellular Microbiology and Physics of Infection Group, Center for Infection and Immunity of Lille, Institut Pasteur de Lille, CNRS, INSERM, CHU Lille, University of Lille, Lille Cedex, France University of Ottawa, Department of Cellular & Molecular Medicine, Ottawa, Ontario, Canada Huazhong Agricultural University, National Key Laboratory of Crop Genetic Improvement, Wuhan, China Macquarie University, Faculty of Medicine, Health and Human Sciences, Department of Biomedical Science, Centre for Motor Neuron Disease Research, Sydney, NSW, Australia University of California, San Francisco Department of Ophthalmology, San Francisco, CA, USA National Yang-Ming University, Department of Life Sciences and Institute of Genome Sciences, Taipei, Taiwan Yale University, Department of Cellular and Molecular Physiology, New Haven, CT, USA School of Biochemistry, University of Bristol, Bristol, UK Penn State College Medicine, Department of Cellular and Molecular Physiology, Hershey, PA, USA University of Greifswald, Institute of Pharmacy, Greifswald, Germany Stockholm University, Department of Biochemistry and Biophysics, Stockholm, Sweden Johannes Kepler University Linz, Kepler University Hospital GmbH, Institute of Pathology and Molecular Pathology, Linz, Austria University Bourgogne Franche-Comté, AgroSup Dijon, PAM UMR A 02.102, Dijon, France IGBMC, Inserm U1258, Cnrs UMR7104, Strasbourg University, Illkirch, France Mayo Clinic, Department of Medicine, Division of Gastroenterology and Hepatology, Rochester, MN, USA University of Virginia, Department of Cell Biology, Charlottesville, VA, USA Macau University of Science and Technology, State Key Laboratory of Quality Research in Chinese Medicine, Taipa, Macau, China The Hong Kong Polytechnic University, Faculty of Health and Social Sciences, Department of Health Technology and Informatics, Hunghom, Hong Kong University of Nottingham, School of Life Sciences, Nottingham, UK Sichuan Academy of Medical Science & Provincial Hospital, Medical School of UESTC, Chengdu, China Université Paris Saclay, Institut des Neurosciences Paris-Saclay (Neuro-PSI)-CNRS UMR 9197, Orsay France McGill University Health Center, Department of Medicine, Cancer Research Program, Montreal, QC, Canada Research Institute of the McGill University Health Centre, Meakins-Christie Laboratories and Translational Research in Respiratory Diseases Program, Montréal, Québec, Canada; McGill University, Department of Critical Care and Division of Experimental Medicine, Montréal, Québec, Canada; UQAM, Faculté des Sciences, Département des Sciences de l'activité physique, Montréal, Canada Ulsan National Institute of Science and Technology, Department of Biological Sciences, Ulsan, Korea National Taipei University of Nursing and Health Sciences, School of Nursing, Taipei, Taiwan KAIST, Department of Biological Sciences, Daejon, Korea Konkuk University, School of Medicine, Department of Anatomy, Seoul, Korea Korea Advanced Institute of Science and Technology, Graduate School of Medical Science and Engineering, Daejeon, Korea QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia Hannam University, Department of Biological Sciences and Biotechnology, Daejeon, South Korea Chungnam National University, Graduate School of Analytical Science and Technology (GRAST), Daejeon 305-764, Republic of Korea University of Michigan, Department of Molecular & Integrative Physiology, Ann Arbor, MI, USA Incheon National University, College of Life Sciences and Bioengineering, Division of Life Sciences, Incheon, Korea Yonsei University College of Medicine, Department of Pharmacology, Seoul, Korea Seoul National University College of Medicine, Department of Biochemistry and Molecular Biology, Seoul, Korea Yonsei University College of Medicine, Severance Biomedical Science Institute and Department of Internal Medicine, Seoul, Korea Ajou University Graduate School of Medicine, Department of Biomedical Sciences, Suwon, Gyeonggi, Korea Seoul National University College of Medicine, Department of Biomedical Sciences, Neuroscience Research Institute, Seoul, Korea University of Kansas Medical Center, Department of Biochemistry and Molecular Biology, Kansas City, KS, USA DGIST, Department of Brain & Cognitive Sciences, Daegu, Korea University of Arizona College of Medicine, Department of Basic Medical Sciences, Phoenix, AZ, USA Ditmanson Medical Foundation Chia-Yi Christian Hospital, Translational Medicine Research Center, Chiayi City, Taiwan Yonsei University College of Medicine, Department of Internal Medicine, Seoul, Korea University of West Florida, Department of Movement Sciences and Health, Pensacola, FL, USA University of Michigan, Rogel Cancer Center, Department of Periodontics and Oral Medicine, Department of Otolaryngology - Head and Neck Surgery, Ann Arbor, MI, USA National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA University of Maribor, Faculty of Medicine, Maribor, Slovenia; University of Maribor, Faculty of Natural Sciences and Mathematics, Department of Biology, Maribor, Slovenia; University of Maribor, Faculty of Chemistry and Chemical Engineering, Maribor, Slovenia; Medical University of Graz, Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Graz, Austria Medical University of Graz, Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Graz, Austria Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, China Institut National de la Santé et de la Recherche Médicale (Inserm), Université de Paris, Paris Cardiovascular Center - PARCC, Paris, France Universidade Federal do Rio Grande do Sul (UFRGS), Center of Biotechnology and Department of Biophysics, Porto Alegre, RS, Brazil USC Norris Comprehensive Cancer Center , Los Angeles, CA, USA University of Pisa, Department of Translational Research and New Technologies in Medicine and Surgery, Pisa, Italy Universidad Autónoma de Madrid, Department of Biology, Madrid, Spain University of São Paulo, School of Pharmaceutical Sciences of Ribeirão Preto, Department of Clinical Analyses, Toxicology and Food Sciences, Ribeirão Preto, SP, Brazil University of Luxembourg, Department of Life Sciences and Medicine, Molecular Disease Mechanisms Group, Belval, Luxembourg The Chinese University of Hong Kong, Faculty of Medicine, School of Biomedical Sciences, Shatin, New Territories, Hong Kong Icahn School of Medicine at Mount Sinai, Department of Medicine, New York, NY, USA Royal Veterinary College, London, UK; UCL Queen Square Institute of Neurology, Department of Neurodegenerative Disease, London, UK La Jolla Institute for Immunology and University of California San Diego, Laboratory of Inflammation Biology, La Jolla, CA, USA College of Life Science and Technology, Jinan University, Guangzhou, China Fudan University, Shanghai Cancer Center and Institutes of Biomedical Sciences, Shanghai, China Sun Yat-sen University, Sun Yat-sen Memorial Hospital, Department of Pathology, Guangzhou, Guangdong Province, China Sichuan University, West China Hospital, State key laboratory of biotherapy, Chengdu, Sichuan, China Virginia Polytechnic Institute, Department of Biological Sciences, Blacksburg, VA, USA Children's Hospital of Soochow University, Institute of Pediatric Research, Suzhou, China Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA Jinan University, College of Life Science and Technology, Department of Biology, Guangzhou, China Virginia Commonwealth University, Departement of Pharmacology and Toxicology, Richmond, VA, USA Fudan University, Hospital of Obstetrics and Gynecology, Institute of Obstetrics and Gynecology, Laboratory for Reproductive Immunology, Shanghai, China South China Normal University, School of Life Sciences, Institute of Insect Science and Technology, Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Guangzhou, China Emory University School of Medicine, Department of Pharmacology and Chemical Biology, Atlanta, GA, USA Boston Children’s Hospital, Harvard Medical School, Departments of Urology and Surgery, Boston, MA, USA Stanford University, Department of Gastroenterology & Hepatology, Stanford, CA, USA Chinese Academy of Agricultural Sciences, Institute of Plant Protection, State Key Laboratory for Biology of Plant Diseases and Insect Pests, Beijing, China Chinese Academy of Agriculture Sciences, Lanzhou Veterinary Research Institute, State Key Laboratory of Veterinary Etiological Biology, Lanzhou, Gansu, China Chinese Academy of Sciences, Hefei Institutes of Physical Science, High Magnetic Field Laboratory, Hefei, Anhui Province, China Army Medical University, Department of Bichemistry and Molecular Biology, Chongqing, Chongqing, China The Wistar Institute, Molecular and Cellular Oncogenesis Program, Philadelphia, PA, USA Sun Yat-sen University, The 3rd Affiliated Hospital of Sun Yat-sen University, Vaccine Research Institute, Guangzhou, China Nanjing Agricultural University, College of Life Sciences, Key Laboratory of Agricultural Environmental Microbiology of Ministry of Agriculture and Rural Affairs, Nanjing , China Free University of Berlin, Department of Biology, Chemistry and Pharmacy, Berlin, Germany Northwest A&F University, College of Life Sciences, Yangling, Shaanxi, China Academia Sinica, Institute of Cellular and Organismic Biology, Taipei, Taiwan Nathan S. Kline Institute, Center for Dementia Research, Orangeburg, NY, USA National Institute of Child Health and Human Development, National Institutes of Health, Cell Biology and Neurobiology Branch, Bethesda, MD, USA Konkuk University, Department of Veterinary Medicine, Seoul, Korea São Paulo State University, Botucatu Medical School, Center for Evaluation of Environmental Impact on Human Health (TOXICAM), Department of Pathology, Botucatu, SP, Brazil San Raffaele Open University and IRCCS San Raffaele Pisana, Laboratorio di Patologia Cellulare e Molecolare, Rome, Italy First Affiliated Hospital of Nanjing Medical University, Department of Neurosurgery, Nanjing, China; Jiangsu Province Hospital, Department of Neurosurgery, Nanjing, China Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan; I-Shou University, College of Medicine, School of Medicine, Kaohsiung, Taiwan Mackay Memorial Hospital, Department of Pediatrics, Taipei, Taiwan; Mackay Medical College, Department of Medicine, New Taipei,Taiwan Zhejiang Academy of Agricultural Sciences, Institute of Plant Protection and Microbiology, State Key Laboratory for Managing Biotic and Chemical Treatments to the Quality and Safety of Agro-products, Hangzhou, China; Zhejiang University, Institute of Biotechnology, Hangzhou, China Life Sciences Institute and Department of Cell & Developmental Biology, University of Michigan, Ann Arbor, MI, USA National Health Research Institutes, Institute of Biomedical Engineering and Nanomedicine, Zhunan, Miaoli, Taiwan Chang Gung Memorial Hospital, Liver Research Center, Linkou, Taoyuan, Taiwan; Chang Gung University, College of Medicine, Graduate Institute of Biomedical Sciences, Taoyuan, Taiwan; Chang Gung University of Science and Technology, College of Human Ecology, Research Center for Chinese Herbal Medicine, Taoyuan, Taiwan The Ohio State University, Wexner Medical Center, Department of Surgery, Columbus, OH, USA School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China Huazhong University of Science and Technology, College of Life Science and Technology, Hubei Bioinformatics and Molecular Imaging Key Laboratory, Key Laboratory of Molecular Biophysics of Ministry of Education, Wuhan, Hubei, China Harvard Medical School, Massachusetts General Hospital, Gastrointestinal Unit/Medicine, Boston, MA, USA. Mayo Clinic, Department of Biochemistry and Molecular Biology, Rochester, MN, USA Brigham and Women's Hospital, Harvard Medical School, Center for Nanomedicine and Department of Anesthesiology, Boston, MA, USA Instituto de Biofisica da UFRJ, Rio de Janeiro, Brazil Technical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Neurology, Munich, Germany Indiana University School of Medicine, Department of Pediatrics and Center for Diabetes and Metabolic Diseases, Indianapolis, IN, USA University of Singapore, Department of Biological Sciences, Singapore University of Maryland School of Medicine, Department of Anesthesiology, Baltimore, MD, USA University of Iowa, Fraternal Order of Eagles Diabetes Research Center, Obesity Research and Education Initiative, Abboud Cardiovascular Research Center, Department of Health and Human Physiology, Iowa City, IA, USA Poznan University of Medical Sciences, Department of Clinical Chemistry and Molecular Diagnostics, Poznan, Poland Duke University, Department of Ophthalmology, Durham, NC, USA Department of Microbiology & Immunology, Dalhousie University, Halifax, Nova Scotia, Canada Institute of Neuroscience of Soochow University, Suzhou, China Chinese Academy of Sciences, Center for Biosafety Mega-Science, Institute of Microbiology, CAS Key Laboratory of Pathogenic Microbiology and Immunology, Chaoyang District, Beijing, China Nankai University, Department of Microbiology, Tianjin, China Guangdong Medical University, Institute of Nephrology, and Zhanjiang Key Laboratory of Prevention and Management of Chronic Kidney Disease, Zhanjiang, Guangdong, China Capital Medical University, Beijing Institute for Brain Disorders, Beijing, China Central South University, School of Life Sciences, Molecular Biology Research Center, Changsha, Hunan, China The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China Columbia University, Naomi Berrie Diabetes Center, Department of Pathology and Cell Biology, College of Physicians and Surgeons, New York, NY, USA University of New Mexico Health Sciences Center, Department of Biochemistry and Molecular Biology, Albuquerque, NM, USA Henan Academy of Agricultural Sciences, Institute of Plant Nutrition, Agricultural Resources and Environmental Science, Jinshui District, Zhengzhou, Henan, China Zhejiang University School of Medicine, Department of Biochemistry and Department of Cardiology of the Second Affiliated Hospital, Hangzhou, Zhejiang, China Zhejiang University, Biotechnology Institute, State Key Laboratory for Rice Biology, Hangzhou, China CAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China Harvard Medical School, Department of Microbiology; Brigham and Women's Hospital, Division of Infectious Diseases, Boston, MA, USA University of Colorado at Boulder, Department of Biochemistry, Boulder, CO, USA ShanghaiTech University, School of Life Science and Technology, Shanghai, China Saarland University, Department of Neurology, Homburg, Germany Johns Hopkins University, Department of Biochemistry and Molecular Biology, Baltimore, MD, USA Shenyang Pharmaceutical University, Department of Pharmacology, Shenyang, China Tsinghua Unversity, School of Life Sciences, Beijing, China University of Texas MD Anderson Cancer Center, Department of Sarcoma Medical Oncology, Houston, TX, USA University of Bourgogne Franche-Comté, Team ’Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism (EA7270)/Inserm, Faculty of Sciences Gabriel, Dijon, France Universitat Autonoma de Barcelona, Departament of Biochemistry and Institut Neurosciences, Faculty of Medicine, Bellaterra, Barcelona, Spain Vall d´Hebron Research Institute, Barcelona, Spain Oslo University Hospital, Institute for Cancer Research, Department of Molecular Cell Biology, Oslo, Norway Harvard Medical School, Brigham and Women's Hospital, Department of Neurology, Boston, MA, USA London School of Hygiene & Tropical Medicine, Department of Infection Biology, London, UK Universidad Autonoma de Madrid, School of Medicine, Department of Pharmacology, Madrid, Spain Universidad Autónoma de Madrid, Departamento de Biología Molecular, Madrid, Spain and Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain Universidad de Zaragoza, IA2, IIS, Laboratorio de Genética Bioquímica (LAGENBIO), Zaragoza, Spain; Universidad de Zaragoza, IA2, IIS, Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Zaragoza, Spain University Medical Center Utrecht, Center for Molecular Medicine, Utrecht, The Netherlands; Regenerative Medicine Center, Utrecht, The Netherlands University of Turin, Department of Veterinary Sciences, Grugliasco (TO), Italy Université de Paris, Centre de Recherche sur l'Inflammation (CRI), Inserm-UMR1149, Paris, France Newcastle University, Institute of Translation and Clinical Studies, Precision Medicine, The Medical School, Newcastle upon Tyne, UK State University of New York at Buffalo, Buffalo, NY, USA Universidad Mayor, Center for Integrative Biology and Geroscience for Brain, Health and Metabolism, Santiago, Chile National University of Singapore, Yong Loo Lin School of Medicine, Department of Physiology, Singapore Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA University of Macau, Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, Taipa, Macao, China Institute of Virology, University Hospital Essen, Essen, Germany Pfizer Inc, DSRD, La Jolla, CA, USA University of St Andrews, School of Medicine, North Haugh, St Andrews, UK Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal and ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal Duke University, School of Medicine, Duke Center for Virology, Department of Molecular Genetics and Microbiology, Durham, NC, USA BC Cancer, Trev and Joyce Deeley Research Centre, Victoria, BC, Canada; University of Victoria, Department of Biochemistry and Microbiology, Victoria, BC, Canada University of Würzburg, Institute of Clinical Neurobiology, Würzburg, Germany University of British Columbia, Centre for Heart Lung Innovation/Department of Pathology and Laboratory Medicine, Vancouver, BC, Canada Kunming Institute of Zoology, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming, Yunnan, China Plymouth University, Peninsula School of Medicine and Dentistry, Plymouth, UK Huazhong Agricultural University, Laboratory of Molecular Nutrition for Aquatic Economic Animals, Fishery College, Wuhan, China RWTH Aachen University, Medical School, Institute of Biochemistry and Molecular Biology, Aachen, Germany International Clinical Research Center, St'Anne University Hospital, Brno, Czech Republic; Institute of Molecular Biology and Biophysics, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Siberia, Russia University of Oslo, Faculty of Medicine, Institute of Basic Medical Sciences, Department of Molecular Medicine, Oslo, Norway; University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Centre for Cancer Cell Reprogramming, Oslo, Norway Justus Liebig University, University Hospital Giessen and Marburg GmbH, Departement of Ophthalmology, Giessen, Germany The Hong Kong Polytechnic University, Department of Health Technology and Informatics, Hong Kong, China Shandong Normal University, Shandong Provincial Key Laboratory of Plant Stress, College of Life Sciences, Jinan, Shandong, China Yale School of Medicine, Department of Cell Biology, New Haven, CT, USA Guangzhou Medical University, Department of Histology and Embryology, Guangzhou, China Soochow University, Institute of Neuroscience, Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases, Suzhou, Jiangsu, China Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, USA Air Force Medical University, Xijing Hospital, Department of Clinical Laboratory, Xi'an, China Tianjin Medical University, Department of Biochemistry and Molecular Biology; School of Basic Medical Sciences, Tianjin Key Laboratory of Medical Epigenetics, Tianjin, China Albert Einstein College of Medicine, Department of Pathology. Bronx, NY, USA Iowa State University, Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Ames, IA, USA Michigan State University, College of Human Medicine, Grand Rapids, MI, USA Ben May Department for Cancer Research, University of Chicago, Chicago IL, USA. Perelman School of Medicine at the University of Pennsylvania, Department of Neuroscience, Philadelphia, PA, USA University of Graz, Institute of Molecular Biosciences, BioTechMed-Graz, BioHealth, Graz, Austria University of Texas Health San Antonio, Department of Medicine, San Antonio, TX, USA Albert Einstein College of Medicine, Institute for Aging Studies, Department of Developmental and Molecular Biology, Bronx, NY, USA RIKEN, Laboratory for Retinal Regeneration, Kobe, Hyogo, Japan Tokyo Medical and Dental University, Department of Cardiovascular Medicine, Tokyo, Japan Justus-Liebig University, Department of Internal Medicine, Universities of Giessen & Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany Part overlaps with Costanza Montagna: Danish Cancer Society Research Center, Computational Biology Laboratory, Copenhagen, Denmark; Danish Cancer Society Research Center, Computational Biology Laboratory, Copenhagen, Denmark Cellular and Molecular Signaling, New York, NY, USA Central Michigan University, Department of Psychology and Neuroscience Program, Mt. Pleasant, MI, USA Inserm U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France University of Naples Federico II, Department of Biology, Naples, Italy Washington University in St. Louis, Department of Cell Biology and Physiology, St. Louis, MO, USA CSIR - Indian Institute of Integrative Medicine, Department of Cancer Pharmacology, Sanat Nagar, Srinagar, Jammu and Kashmir, India National University of Singapore, Yong Loo Lin School of Medicine, Department of Physiology, Mitochondrial Physiology and Metabolism Lab, Singapore; National University of Singapore, NUHS Centre for Healthy Ageing, Singapore Center for Global Health, Catholic University of the Sacred Heart, Rome, Italy Oregon Health and Science University, Knight Cardiovascular Institute, Portland, OR, USA Iowa State University, Department of Biomedical Sciences, Ames, IA, USA The Chinese University of Hong Kong, The Prince of Wales Hospital, The Faculty of Medicine, Department of Orthopaedics and Traumatology, New Territories, Shatin, Hong Kong, China Dana-Farber Cancer Institute, Division of Genomic Stability and DNA Repair, Department of Radiation Oncology, Boston, MA, USA German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; CAESAR Research Center, Bonn, Germany Vita-Salute San Raffaele University & IRCCS San Raffaele Scientific Institute, Division of Immunology, Transplantation and Infectious Diseases, Milano, Italy Virginia Commonwealth University School of Medicine, VCU Institute of Molecular Medicine, Massey Cancer Center, Department of Microbiology and Immunology, Richmond, VA, USA Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India KU Leuven, Department of Imaging and Pathology, Leuven, Belgium University College London, School of Pharmacy, Department of Pharmacology, London, United Kingdom Massachusetts General Hospital, Department of Molecular Biology, Boston, MA, USA Université Côte d'Azur, INSERM, C3M, Nice, France Presidio San Paolo Polo Universitario, Dipartimento di Scienze della Salute San Paolo, Milano, Italy University of Milan, Department of Pharmacological and Biomolecular Sciences, Milan, Italy Consiglio Nazionale delle Ricerche, Istituto di Biochimica e Biologia Cellulare, Monterotondo scalo (RM), Italy University of Camerino, School of Pharmacy, Camerino, MC, Italy University of Oviedo, Principality of Asturias Institute for Biomedical Research, Department of Functional Biology, Oviedo, Spain Washington University in St. Louis, Department of Biology, St. Louis, MO, USA UMBC, Department of Chemical, Biochemical and Environmental Engineering, Baltimore, MD, USA University of Vienna, Max Perutz Labs, Department of Biochemistry and Cell Biology, Vienna BioCenter, Vienna, Austria Harvard Medical School, Department of Biological Chemistry and Molecular Pharmacology, Boston, MA, USA European Institute of Oncology (IEO) IRCCS, Department of Experimental Oncology, Milan, Italy; University of Milano, Department of Oncology and Hemato-Oncology, Milan, Italy KU Leuven, Department of cellular and Molecular Medicine, Laboratory of cellular transport systems, Leuven, Belgium Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Department of Biotechnology, Madrid, Spain Laboratorio de Genética Bioquímica (LAGENBIO), Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Instituto Agroalimentario de Aragón-IA2, Instituto de Investigación Sanitaria Aragón-IISA, Universidad de Zaragoza, Zaragoza, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto Carlos III, Zaragoza, Spain University of Las Palmas de Gran Canaria, Department of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), Las Palmas de Gran Canaria, Spain Instituto de Investigaciones Biomédicas “Alberto Sols”, CSIC-UAM, Madrid, Spain Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA University of Cambridge, MRC Mitochondrial Biology Unit, Cambridge, UK National Institutes of Health, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, AC, Unidad de Biotecnología Médica y Farmacéutica, Guadalajara, Jalisco, México Albert Einstein College of Medicine, Radiation Oncology, Bronx, NY, USA Vall d'Hebron research Institute-UAB/Neurodegenerative Diseases Group, Barcelona, Spain University of São Paulo, Institute of Biomedical Sciences, Department of Anatomy, Laboratory of Functional Neuroanatomy of Pain, São Paulo, Brazil Laboratory of Immunoendocrinology, Department of Clinical and Toxicological Analyses, University of São Paulo, São Paulo, Brazil Universidade Anhanguera de São Paulo, Programa de Pós-graduação Stricto sensu e Pesquisa, São Paulo, Brazil Università Cattolica del Sacro Cuore, Rome, Italy Institut Jean-Pierre Bourgin, INRAE, AgroParisTech, Université Paris-Saclay, 78000 Versailles, France University of Minnesota, Department of Biochemistry, Molecular Biology and Biophysics and Department of Medicine, Minneapolis, MN, USA Università degli Studi di Milano, Dipartimento di Scienze della Salute, Milano, Italy Universidad Nacional Autónoma de México, Instituto de Fisiología Celular, División de Neurociencias, Departamento de Neuropatología Molecular, Mexico, DF, Mexico MRC Laboratory of Molecular Biology, Cambridge, UK University of Rome “Sapienza”, Department of Experimental Medicine, Rome, Italy Center for gender-specific medicine, Italian National Health Institute, Rome, Italy Biodonostia Health Research Institute, group of Cellular Oncology; IKERBASQUE; CIBERfes, Spain Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Department of Cardiovascular Medicine, Kyoto, Japan CHU Clermont-Ferrand, Chirurgie Gynécologique, Clermont-Ferrand, France; Université Clermont Auvergne, Institut Pascal, UMR6602, CNRS/UCA/SIGMA, Clermont-Ferrand, France University of Chieti-Pescara, Department of Medical, Oral, and Biotechnological Science, Chieti, Italy University of California, Davis, Department of Dermatology, Sacramento, CA, USA CONACYT - Centro de Investigación Biomédica de Oriente, Instituto Mexicano del Seguro Social, Puebla, Mexico IRCCS “Casa Sollievo della Sofferenza”, Opera di Padre Pio da Pietrelcina, Division of Internal Medicine and Chronobiology Unit, Department of Medical Sciences, San Giovanni Rotondo (FG), Italy Sapienza University of Rome, Department of Biology and Biotechnology C. Darwin, Rome, Italy University of Texas Health Science Center at Houston, Center for Stem Cell and Regenerative Disease, Institute of Molecular Medicine (IMM), Houston, TX, USA Cleveland Clinic, Lerner Research Institute, Department of Inflammation & Immunity, Cleveland, OH, USA University of Arkansas for Medical Sciences, Fay W. Boozman College of Public Health, Department of Environmental and Occupational Health, Little Rock, AR, USA University College Cork, Department of Cancer Research, Cork, Ireland Academic Decency, MeTooSTEM, Nashville, TN, USA Mayo Clinic, Rochester, MN, USA Translational Stem Cell Biology Metabolism Program, Research Programs Unit, University of Helsinki, Helsinki, Finland Department of Anatomy, Faculty of Medicine, Helsinki, Finland PSL Research University, Equipe labelisée par la Ligue Contre le Cancer, Institut Curie, Inserm, U830, Stress and Cancer laboratory, Paris, France Sprott Centre for Stem Cell Research, Ottawa Hospital Research Institute, and University of Ottawa, Department of Medicine, Ottawa, ON, Canada University of Szeged, Department of Medical Microbiology and Immunobiology, Szeged, Hungary University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA University of Amsterdam, Medical Biochemistry, Amsterdam UMC, Amsterdam, The Netherlands Leiden University, Institute of Biology Leiden, Leiden, The Netherlands; The City University of New York, Queens College, The Graduate Center of the City University of New York, Department of Biology, Flushing, NY, USA UiT The Arctic University of Norway, Department of Pharmacy, Pharmacology Research Group, Tromso, Norway Childrens' Hospital, Hannover Medical School, Hannover, Germany Anhui Province Key Laboratory of Medical Physics and Technology, Center of Medical Physics and Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui, China; University of Science and Technology of China, Anhui, China Laboratory of Cell Biology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil Indian Institute of Technology Delhi, Kusuma School of Biological Sciences, New Delhi, India University of Cincinnati, Division of Hematology/Oncology, Cincinnati, OH, USA University of Pretoria, School of Medicine, Faculty of Health Sciences, Department of Physiology, Pretoria, South Africa Laboratoire d'Optique et Biosciences, Ecole Polytechnique, CNRS, Inserm, Institut Polytechnique de Paris, Palaiseau, France University of New Mexico, Clinical and Translational Sciences Center, Albuquerque, NM, USA Carité-Universitaetsmedizin Berlin, Campus Mitte, Institut für Integrative Neuroanatomie, Berlin, Germany Ruprecht-Karls University of Heidelberg, Women's Hospital, Department of Gynecological Endocrinology and Fertility Disorders, Heidelberg, Germany Institut Jean-Pierre Bourgin, INRA, AgroParisTech, CNRS, Université Paris-Saclay, Versailles, France University of Duisburg-Essen, Centre for Medical Biotechnology, Faculty of Biology, Essen, Germany Tianjin Medical University, Department of Immunology, School of Basic Medical Sciences, Tianjin, China INSERM Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse, Toulouse, France Shandong University, School of Life Science, Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, Qingdao, China Fondazione IRCCS Casa Sollievo della Sofferenza, Poliambulatorio Giovanni Paolo II, Division of Medical Genetics, San Giovanni Rotondo (FG), Italy Hirosaki University Graduate School of Medicine, Institute of Brain Science, Department of Neuropathology, Hirosaki, Japan; UCL Queen Square Institute of Neurology, Queen Square Brain Bank for Neurological Disorders, London, UK National Medicines Institute, Department of Drug Biotechnology and Bioinformatics, Warszawa, Poland University of Washington School of Medicine, Department of Biochemistry, Seattle, WA, USA University of Washington, Departments of Medicine, Microbiology and Genome Sciences, Seattle, WA, USA Sage Therapeutics, Cambridge, MA, USA European Neuroscience Institute (ENI) - A Joint Initiative of the University Medical Center Göttingen and the Max Planck Society, Göttingen, Germany Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Department of Molecular Sciences, Uppsala BioCenter, Uppsala, Sweden; Heidelberg University, Center for Organismal Studies, Neuenheimer Feld, Heidelberg, Germany Kashan University of Medical Sciences, Research Center for Biochemistry and Nutrition in Metabolic Disease, Kashan, Iran Tehran University of Medical Sciences, School of Medicine, Department of Medical Immunology, Tehran, Iran Macquarie University, Faculty of Medicine and Health Sciences, New South Wales, Australia Indian Institute of Technology Jodhpur, Cellular and Molecular Neurobiology Unit, Jodhpur, Rajasthan, India Amrita Vishwa Vidyapeetham, School of Biotechnology, Kollam, Kerala, India University of Nebraska Medical Center, Department of Cellular and Integrative Physiology, Omaha, NE, USA University of Campania L. Vanvitelli, Department of Precision Medicine, Naples, Italy; Institute of Genetic Research, Biogem scarl, Laboratory of Molecular and Precision Oncology, Ariano Irpino (AV), Italy University of Campania “Luigi Vanvitelli”, Department of Precision Medicine, Naples, Italy Université Toulouse III, Toulouse, France Sapporo Medical University, Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo, Japan University of California San Diego, Department of Pharmacology, La Jolla, CA, US University of Colorado Denver, Department of Medicine, Aurora, CO, USA Health Sciences University of Hokkaido, College of Rehabilitation Sciences, Department of Physical Therapy, Ishikari-Tobetsu, Hokkaido, Japan Nagasaki University Graduate School of Biomedical Sciences, Department of Infectious Diseases, Nagasaki, Japan Tokyo Medical University, Department of Biochemistry, Tokyo, Japan Aarhus University, Department of Biomedicine, Aarhus, Denmark Université Côte d'Azur (UCA), Institute for Research on Cancer and Aging of Nice (IRCAN), Centre Antoine Lacassagne, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Fédération Hospitalo-Universitaire (FHU) OncoAge, Nice, France Kerman University of Medical Sciences, Institute of Neuropharmacology, Pharmaceutics Research Center, Kerman, Iran MVR Cancer Hospital and Research Institute, Molecular Oncology, Cancer Genomics/Proteomics, Kerala, India University of Kaiserslautern, Department of Biology, Plant Physiology, Kaiserslautern, Germany International Centre for Genetic Engineering and Biotechnology, New Delhi, India Department of Experimental Pathology, Institute of Biomedical Research of Barcelona, Spanish Research Council (IIBB-CSIC); IDIBAPS and CIBEREHD, Barcelona, Spain Washington University in St. Louis, Professor of Obstetrics and Gynecology, St. Louis, MO, USA Università della Svizzera italiana (USI), Faculty of Biomedical Sciences, Institute for Research in Biomedicine, Bellinzona, Switzerland; School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland University “Magna Graecia” of Catanzaro, Department of Health Sciences, Catanzaro, Italy Aarhus University Hospital, Steno Diabetes Center Aarhus, Aarhus, Denmark; Aarhus University, Department of Clinical Medicine, Research Laboratory for Biochemical Pathology, Aarhus, Denmark Université de Lyon, ENSL, UCBL, CNRS, LBMC, UMS 3444 Biosciences Lyon Gerland, Lyon, France Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Department of Molecular Biomedicine, Laboratory of Cell Death and Cancer Therapy, Madrid, Spain Bispebjerg Hospital, Institute of Sports Medicine Copenhagen, Copenhagen,Denmark; UniCamillus, Saint Camillus International University of Health Sciences, Rome, Italy University of Maryland School of Medicine, Center for Biomedical Engineering and Technology, Baltimore, MD, USA Università degli Studi di Sassari, Dipartimento di Scienze Biomediche, Sassari, Italy Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Immunopathology and Cancer Biomarkers, Aviano, Italy University of Virginia, Department of Biology, Charlottesville, VA, USA University of Exeter Medical School, European Centre for Environment & Human Health (ECEHH), Knowledge Spa, Royal Cornwall Hospital, Truro, Cornwall, UK; Plymouth Marine Laboratory (PML), Plymouth, UK; University of Plymouth, School of Biological & Marine Sciences, Plymouth, UK National Institute of Genetic Engineering and Biotechnology, Institute of Medical Biotechnology, Molecular Medicine Department, Tehran, Iran University of Pittsburgh, Department of Medicine, Aging Institute, Pittsburgh, PA, USA Fondazione IRCCS Istituto Neurologico Carlo Besta, Neuromuscular Diseases and Neuroimmunology Unit, Milano, Italy University of Coimbra, Institute of Physiology, Faculty of Medicine, Coimbra, Portugal and CNC - Center for Neuroscience and Cell Biology, Coimbra, Portugal European Institute of Oncology (IEO) IRCCS, Department of Experimental Oncology, Milan, Italy Laboratory of Neurodevelopment, Neurogenetics and Molecular Neurobiology, IRCCS Fondazione Santa Lucia, Rome, Italy National Autonomous University of Mexico (UNAM), Department of Neurodevelopment and Physiology, Institute of Cellular Physiology, Mexico City, Mexico Sapienza University of Rome, Department of Anatomy, Histology, Forensic Medicine & Orthopedics, Histology & Medical Embryology Section, Rome, Italy Ifremer, SG2M-LGPMM, Laboratoire de Génétique et Pathologie des Mollusques Marins, La Tremblade, France Swansea University Medical School, Molecular Neurobiology group, Swansea, United Kingdom Normandie University, UNIROUEN, INSERM U1239, DC2N, Rouen, France; Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France Juntendo University Graduate School of Medicine, Department of Physiology, Tokyo, Japan University of British Columbia, Department of Ophthalmology and Visual Sciences, Vancouver, British Columbia, Canada Kindai University, Pharmaceutical Research and Technology Institute, Higashi-Osaka, Osaka, Japan Saitama University, Department of Regulatory Biology, Saitama, Japan Pontificia Universidad Católica de Chile, Faculty of Biological Sciences, Department of Physiology, Santiago de Chile, Chile The University of Texas McGovern Medical School at Houston, Department of Neurology, Houston, TX, USA Weill Cornell Medicine, Rockefeller University Campus, Department of Pathology and Laboratory Medicine, New York, NY, USA Max Planck Institute for the Biology of Ageing, Cologne, Germany Federal University of Ceara, Drug Research and Development Center, Fortaleza, CE, Brazil Texas Tech University, Department of Nutritional Sciences & Obesity Research Institute, Lubbock, TX, USA University of Münster, Institute of Medical Microbiology, Münster, Germany Indian Council of Medical Research - National AIDS Research Institute, Division of Molecular Virology, Pune, MH, India New York University Medical School, Laura and Isaac Perlmutter Cancer Center, Department of Radiation Oncology, New York, NY, USA University of Colorado Denver, Children's Hospital Colorado, Morgan Adams Foundation Pediatric Brain Tumor Research Program, Aurora, CO CNRS Biotechnology and cell signaling, Ecole Supérieure de Biotechnologie de Strasbourg, Strasbourg University/Laboratory of excellence Medalis; University of Strasbourg Institute for Advanced Study, Strasbourg, France ICREA, Pompeu Fabra University (UPF), Department of Experimental and Health Sciences, Ciberned, Barcelona, Spain; Spanish National Cardiovascular Research Center (CNIC), Madrid, Spain National Hospital for Paraplagics (Sescam) Research Unit, Molecular Neuroprotection Group, Toledo, Spain University of Zürich, Institute of Experimental Immunology, Viral Immunobiology, Zürich, Switzerland King's College London, School of Cardiovascular Medicine and Sciences, London, UK Old Dominion University, Frank Reidy Research Center for Bioelectrics, Norfolk, VA, USA Royal College of Surgeons in Ireland, Department of Physiology & Medical Physics, Dublin 2, Ireland University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada Genentech, Inc. Department of Cancer Immunology, South San Francisco, CA, USA University of Helsinki, Faculty of Pharmacy, Division of Pharmacology and Pharmacotherapy/Drug Research Program, Helsinki, Finland Washington University School of Medicine, Department of Obstetrics and Gynecology, and Department of Pathology and Immunology, St. Louis, MO, USA University of Rzeszow, Institute of Biology and Biotechnology, Department of Biotechnology, Rzeszow, Poland Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, P.O. Box 19395-5487, Iran. Cornell University, Department of Entomology, Ithaca, NY, USA Rutgers-New Jersey Medical School, Department of Cell Biology and Molecular Medicine, Newark, NJ, USA University Hospital of Lausanne, Central Laboratory of Hematology, Lausanne, Switzerland Kyoto University, Department of Microbiology, Graduate School of Medicine, Kyoto, Japan Gladstone Institute of Neurological Disease and University of California, San Francisco, Department of Neurology, San Francisco, CA, USA Tokyo Institute of Technology, School of Life Science and Technology, Yokohama, Japan University of South Florida, Department of Cell Biology, Microbiology, and Molecular Biology, Tampa, FL, USA “Sapienza” University of Rome, Department of Clinical and Molecular Medicine, Laboratory affiliated to Istituto Pasteur Italia Fondazione Cenci Bolognetti, Rome, Italy University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK Soroka University Medical Center, Institute of Hematology and Ben-Gurion University of the Negev, Faculty of Health Sciences, Department of Clinical Biochemistry and Pharmacology, Beer-Sheva, Israel Niigata University, Brain Research Institute, Department of Neurosurgery, Niigata, Japan Nelson Mandela University, Department of Biochemistry and Microbiology, Port Elizabeth, South Africa Ecole Polytechnique Fédérale de Lausanne (EPFL), Institute of Bioengineering (IBI) and Swiss Institute for Experimental Cancer Research (ISREC), Laboratory of Regenerative Hematopoiesis, Lausanne, Switzerland; Centre Hospitalier Universitaire Vaudois (CHUV), Departments of Oncology and Laboratory Medicine, Hematology Service, Lausanne, Switzerland University of Arizona, Department of Medicine, Tucson, AZ, USA Georgia State University, Department of Biology, Atlanta, GA, USA University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research, Copenhagen, Denmark Radboud University Medical Center, Department of Internal Medicine, Nijmegen, The Netherlands Maastricht University Medical Center, CARIM School for Cardiovascular Diseases, Department of Pathology, Maastricht, The Netherlands University Hospital Basel, Department of Biomedicine, Ocular Pharmacology and Physiology, Basel, Switzerland Karolinska Institutet, Department of Women's and Children's Health, Stockholm, Sweden; Astrid Lindgren Children’s Hospital, Karolinska University Hospital, Solna, Sweden King's College London GKT School of Medical Education, London, UK The University of Sydney, Kolling Institute, Renal Medicine, Sydney, New South Wales, Australia University of Kansas Medical Center. Department of Pharmacology, Toxicology and Thereapeutics, Kansas City, KS, USA Trinity College Dublin, Department of Clinical Medicine, Trinity Centre for Health Sciences, Dublin, Ireland Army Medical University (Third Military Medical University), Daping Hospital, Center of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Laboratory for the Prevention and Rehabilitation of Military Training Related Injuries, Chongqing, China University of Ferrara, Department of Chemical and Pharmaceutical Sciences, Ferrara, Italy National Hospital for Paraplegics (SESCAM), Research Unit, Molecular Neuroprotection Group, Toledo, Spain East Tennessee State University, Quillen College of Medicine, Center of Excellence for Inflammation, Infectious Diseases, and Immunity, Department of Medicine, Johnson City, TN, USA ICMR-Vector Control Research Center, Unit of Microbiology and Immunology, Puducherry, India University of Kansas School of Medicine, Department of Anatomy and Cell Biology, Kansas City, KS, USA New York University School of Medicine, Departments of Psychiatry and Cell Biology, and the Nathan Kline Institute, Orangeburg, NY, USA Faculdade de Medicina e Ciências Biomédicas, Universidade do Algarve, Faro, Portugal; ABC-RI, Algarve Biomedical Center Research Institute, Faro, Portugal; Centre for Biomedical Research, Faro, Portugal Duke University, Department of Biology and Howard Hughes Medical Institute, Durham, NC, USA University of Split, School of Medicine, Split, Croatia Doshisha University Graduate School of Brain Science, Laboratory of Structural Neuropathology, Kyoto, Japan Center for Molecular Biology of Heidelberg University (ZMBH) and German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Heidelberg, Germany Danish Cancer Society Research Center, Unit for Cell Death and Metabolism, Center for Autophagy, Recycling and Disease, Copenhagen, Denmark; University of Copenhagen, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, Copenhagen N, Denmark Trinity College Dublin, Trinity Translational Medicine Institute, Dublin, Ireland David Geffen School of Medicine at UCLA, Department of Microbiology, Immunology, and Molecular Genetics, Los Angeles, CA, USA University of Messina, Sicily, Italy Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany; German Cancer Research Center (DKFZ), and German Cancer Consortium (DKTK), Clinical Cooperation Unit Pediatric Oncology, Im Neuenheimer Feld, Heidelberg, Germany National Institute of Infectious Diseases, Department of Bacteriology I, Toyama, Tokyo, Japan Université de Paris, Centre de recherche sur l'inflammation, Team Gut Inflammation, Inserm, U1149, CNRS, ERL8252, Paris, France University of Iceland, Faculty of Medicine, Biomedical center, Reykjavik, Iceland Hollings Cancer Center, Department of Biochemistry and Molecular Biology, Charleston, SC, USA Ewha Womans University, Department of Life Science, Immune and Vascular Cell Network Research Center, National Creative Initiatives, Seoul, Korea Chosun University, School of Medicine, Gwangju, Korea Yonsei University, Wonju, Korea Yamaguchi University, Joint Faculty of Veterinary Medicine, Laboratory of Veterinary Pharmacology, Yoshida, Yamaguchi, Japan Hyogo College of Medicine, Department of Genetics, Hyogo, Japan University of Perugia, Department of Medicine and Surgery, Perugia, Italy Stanford University, School of Medicine, Department of Pathology, CA, USA Osaka University, Laboratory of Mitochondrial Dynamics, Graduate School of Frontier Biosciences, Osaka, Japan Tokyo Medical and Dental University, Tokyo, Japan. Kyoto University of Advanced Science, Faculty of Bioenvironmental Science, Kameoka, Kyoto, Japan University of Porto, REQUIMTE/UCIBIO, Faculty of Pharmacy, Porto, Portugal Amgen Inc., South San Francisco, CA, USA University of California, Berkeley, Departments of Molecular and Cell Biology and Nutritional Sciences and Toxicology, Berkeley, CA, USA; Chan Zuckerberg Biohub, San Francisco, CA, USA Rutgers University, Center for Advanced Biotechnology and Medicine, Piscataway, NJ, USA University of Defense, Faculty of Military Health Sciences, Department of Radiobiology, Hradec Kralove, Czech Republic The Chinese University of Hong Kong, Lui Che Woo Institute of Innovative Medicine, Centre for Cardiovascular Genomics and Medicine (CCGM), Shatin, Hong Kong, China; The Chinese University of Hong Kong, Faculty of Medicine, Department of Medicine & Therapeutics, Shatin, Hong Kong, China; Hong Kong Hub of Paediatric Excellence (HK HOPE), Hong Kong Children’s Hospital, Kowloon, Hong Kong, China; Xiamen University, Xiamen Cardiovascular Hospital, Institute for Translational Medicine, Xiamen, China; Chinese... The University of Illinois at Chicago College of Medicine, Department of Pharmacology, Chicago, IL, USA Pontificia Universidad Católica de Chile, Escuela de Medicina and Centro Interdisciplinario de Neurociencias, Facultad de Medicina, Departamento de Neurología, Santiago, Chile University of Pennsylvania Perelman School of Medicine and Division of Neurology, The Children’s Hospital of Philadelphia, Department of Neurology, Philadelphia, PA, USA Suez Canal University, Faculty of Veterinary Medicine, Ismailia, Egypt University of Wisconsin-Madison, Center for Quantitative Cell Imaging and Department of Botany, Madison, WI, USA German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Molecular Toxicology, Nuthetal, Germany Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; Institute of Molecular Bioimaging and Physiology (IBFM), CNR, Milan, Italy University of Southern California, Keck School of Medicine, Department of Molecular Microbiology and Immunology, Los Angeles, CA, USA University Medical Center Göttingen, Center for Biostructural Imaging of Neurodegeneration, Department of Experimental Neurodegeneration, Göttingen, Germany; Max Planck Institute for Experimental Medicine, Göttingen, Germany; Newcastle University, The Medical School, Institute of Neuroscience, Newcastle upon Tyne, UK Oslo University Hospital and University of Oslo, Department of Pathology, Tumor Immunology Lab, Oslo, Norway Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Medical Biology Department, Istanbul, Turkey Texas Biomedical Research Institute, Host-Pathogen Interactions Program, San Antonio, TX, USA Baylor College of Medicine, Department of Molecular and Human Genetics, Houston, TX, USA University of Naples Federico II, Department of Molecular Medicine and Medical Biotechnology, Naples, Italy Université de Paris, Centre de Recherche des Cordeliers, Paris, France Fondazione IRCCS Ospedale San Raffaele, Division of Neuroscience, Milan, Italy University of São Paulo, Department of Parasitology, São Paulo, Brazil University of Rome Tor Vergata, Department of Clinical Sciences and Translational Medicine, Rome, Italy Goethe University Frankfurt, Buchmann Institute for Molecular Life Sciences (BMLS), Frankfurt am Main, Germany Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China Affiliated Hospital of GuangDong Medical University, Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Zhanjiang, Guangdong, China Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA National Center of Biomedical Analysis, Beijing, China The Children's Hospital of Philadelphia, Center for Applied Genomics, Philadelphia, PA, USA University of Pittsburgh Medical Center, Department of Pediatrics, Pittsburgh, PA, USA University of Alberta, Department of Biochemistry, Edmonton, Canada University of Salento, Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), Lecce, Italy Danish Cancer Society Research Center, Computational Biology Laboratory, Copenhagen, Denmark Max Perutz Labs, University of Vienna, Vienna Biocenter (VBC), Vienna, Austria Quadram Institute Bioscience, Department of Gut, Microbes and Health, Norwich, UK Waksman Institute, Department of Genetics, Rutgers University, Piscataway, NJ, USA Dong-A University Medical School, Department of Molecular Neuroscience, Busan, Korea Medical College of Wisconsin, Department of Biochemistry, Milwaukee, WI, USA Incheon National University, Division of Life Sciences, College of Life Sciences and Bioengineering, Incheon, Korea Yonsei University, Division of Biological Science and Technology, Wonju, Korea Chonnam National University, The Future Life & Society Research Center, Gwangju, Korea Chonbuk National University, Department of VeterinaryMedicine, Iksan, Korea Ben Gurion University of the Negev, Department of Chemistry, Be'er Sheva, Israel KU Leuven, Department of Cellular and Molecular Medicine & Leuven Kanker Instituut, Leuven, Belgium Sanofi, Vitry Sur Seine, France Mayo Clinic, Department of Physiology and Biomedical Engineering, Rochester, MN, USA VA San Diego Healthcare Systems and University of California, San Diego, Department of Anesthesiology, La Jolla, CA, USA Internal Medicine 1, Brandenburg Hospital, Faculty of Health Sciences, Joint Faculty of the Brandenburg University of Technology Cottbus Senftenberg, the Brandenburg Medical School Theodor Fontane and the University of Potsdam, Brandenburg, Germany IRCM, Institut de Recherche en Cancérologie de Montpellier, Tumor Microenvironment and Resistance to Treatment Laboratory, INSERM U1194, Université de Montpellier, Institut régional du Cancer de Montpellier, Montpellier, France Universidad Nacional Autónoma de México, Instituto de Biotecnología, Departamento de Medicina Molecular y Bioprocesos, Laboratorio de Neuroinmunobiología, Cuernavaca, Morelos, México Universidad de Chile, School of Medicine, Instituto de Ciencias Biomédicas, Santiago de Chile, Chile Friedrich-Loeffler-Institut, Insitute of Immunology, Greifswald - Insel Riem, Germany The Fourth Military Medical University, National Key Discipline of Cell Biology, Department of Physiology and Pathophysiology, Xi’an, Shaanxi, China Weizmann Institute of Science, Department of Plant and Environmental Sciences, Rehovot, Israel Centro de Investigaciones Biológicas CSIC, Department of Cellular and Molecular Biology, Madrid, Spain Sun Yat-Sen University, Sun Yat-sen Memorial Hospital, Department of Neurology, Guangzhou City, Guangdong, China University of Padova, Department of Biomedical Sciences, Padova, Italy Fondazione G. Pascale, Istituto Nazionale Tumori IRCCS, Cell Biology and Biotherapy Unit, Naples, Italy University of Coimbra, CNC – Center for Neuroscience and Cell Biology & Faculty of Medicine & CIBB – Center for Innovative Biomedicine and Biotechnology, Coimbra, Portugal Universidade Federal de São Paulo, Paulista School of Medicine, Departament of Pharmacology, São Paulo, Brazil São Paulo State University, College of Agronomy Sciences, Department of Bioprocesses and Biotechnology, Center for Evaluation of Environmental Impact on Human Health (TOXICAM), Botucatu, SP, Brazil University of Melbourne, Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia University of Granada, Faculty of Pharmacy, Department of Physical Chemistry, Granada, Spain University of Nebraska Medical Center, Department of Pharmacology and Experimental Neuroscience, Omaha, NE, USA State University of New York, Upstate Medical University, Departments of Medicine, Microbiology and Immunology, Biochemistry and Molecular Biology, Syracuse, NY, USA Università degli Studi di Milano, Department of Biomedical and Clinical Sciences “L. Sacco”, Milan, Italy University of Calabria, Department of Biology, Ecology and Earth Sciences, Centre for Microscopy and Microanalysis (CM2), Rende (CS), Calabria, Italy Baruch S. Blumberg Institute, Pennsylvania Cancer and Regenerative Medicine Research Center, Wynnewood, PA, USA; Xavier University School of Medicine, Woodbury, NY, USA National Jewish Health and the University of Colorado, Denver, CO, USA University of Oslo, Oslo University Hospital and Institute for Clinical Medicine, Department of Ophthalmology, Center for Eye Research, Oslo, Norway Health and Medical University, Potsdam, Germany Ulm University, Institute of Biochemistry and Molecular Biology, Faculty of Medicine, Ulm, Germany Washington University, Division of Infectious Diseases, Department of Medicine and Molecular Microbiology, St. Louis, MO, USA Third Military Medical University, Department of Occupational Health, Chongqing, China Virginia Polytechnic Institute and State University, School of Neuroscience, Blacksburg, VA, USA Aix Marseille Université, CNRS, INSERM, CIML, 13288 Marseille cedex 9, France; Institute for Research in Biomedicine (iBiMED) and Ilidio Pinho Foundation, Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal; Shanghai Institute of Immunology, Department of Microbiology and Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, PR China Karolinska Institutet, Department of Biosciences and Nutrition, Huddinge, Sweden Consejo Superior de Investigaciones Científicas (CSIC), Instituto de Biología Molecular y Celular del Cáncer (IBMCC), Centro de Investigación del Cáncer (CSIC-Universidad de Salamanca), Universidad de Salamanca, Campus Unamuno, Salamanca. Spain Tel Aviv University, School of Neurobiology, Biochemistry and Biophysics, Tel Aviv, Israel The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, TX, USA Radboud University Medical Center, Nijmegen, The Netherlands Ruhr-Universität Bochum, Medizinische Fakultät, Biochemie Intrazellulärer Transportprozesse, Bochum, Germany Achucarro Basque Center for Neuroscience, Department of Pharmacology, University of the Basque Country EHU/UPV, Leioa, Bizkaia, Spain University of Cologne, Center for Biochemistry, Cologne, Germany Moscow State University, A.N.Belozersky Institute of Physico-Chemical Biology, Laboratory of Structure and function of mitochondria, Moscow, Russia UCL Queen Square Institute of Neurology, London, UK Monash Biomedicine Discovery Institute and Monash University, Department of Anatomy and Developmental Biology, Melbourne, Victoria, Australia Georg-August University Göttingen, Institute of Microbiology and Genetics, Department of Genetics of Eukaryotic Microorganisms, Göttingen, Germany Buchmann Institute & Institute of Biochemistry II, Medical Faculty, Goethe University, Frankfurt, Germany Cancer Research Center of Toulouse, UMR 1037 Inserm-university of Toulouse, Toulouse, France Mahidol University, Department of Microbiology, Faculty of Science, Ratchathewi, Bangkok, Thailand Erasmus University Medical Center, Department of Epidemiology; Division of Pharmacology, Department of Internal Medicine, Rotterdam, The Netherlands The Hospital for Sick Children, Translational Medicine Program, Toronto, Canada St. Jude Children’s Research Hospital, Department of Cell and Molecular Biology, Memphis, TN, USA University of Oxford, Nuffield Department of Women's and Reproductive Health, Oxford, UK University of California, Davis, Department of Molecular and Cellular Biology, Davis, CA, USA University of Iowa, Department of Biology, Aging Mind and Brain Initiative, Iowa City, IA, USA Jagiellonian University, Department of Evolutionary Immunology, Faculty of Biology, Krakow, Poland Temple University, Alzheimer's Center at Temple, Philadelphia, PA, USA Eberhard Karls University Tübingen, Interfaculty Institute of Cell Biology, Tübingen, Germany University of Cyprus, Department of Biological Sciences, Bioinformatics Research Laboratory, Nicosia, Cyprus Lifelong Health, South Australian Health & Medical Research Institute, North Terrace, Adelaide, Australia University of Wisconsin-Madison, Department of Medicine and Neuroscience, Madison, WI, USA Dalhousie University, Department of Biochemistry and Molecular Biology, Dalhousie Medicine New Brunswick, Saint John, NB, Canada National Center for Cell Science, Pune, India CURML, University Center of Legal Medicine, Lausanne University Hospital, Lausanne, Switzerland Chinese Academy of Sciences, Kunming Institute of Zoology, Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences, Kunming, Yunnan, China Lanzhou University, School of Life Sciences, Lanzhou, China Zhejiang University, College of Medicine, The First Affiliated Hospital, Malignant Lymphoma Diagnosis and Therapy Center, Hangzhou, Zhejiang, China China Pharmaceutical University, School of Basic Medicine and Clinical Pharmacy, State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Nanjing, China Sanofi, Biologics Research, 49 New York Ave, Framingham, MA, USA University of Waterloo, Department of Kinesiology, Waterloo, Ontario, Canada Instituto de Investigaciones Biomedicas en Retrovirus y Sida, Universidad de Buenos Aires-CONICET, Argentina University of Pittsburgh, Department of Pathology; University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA Dartmouth College, Department of Chemistry, Hanover, NH, USA Boston University, Department of Pathology and Laboratory Medicine, Boston, MA, USA Tehran University of Medical Sciences, Cancer Biology Research Center, Tehran, Iran Penn State University College of Medicine, Department of Cellular and Molecular Physiology, Hershey, PA, USA University of Alabama at Birmingham, Cardiac Aging & Redox Signaling Laboratory, Molecular and Cellular Pathology, Department of Pathology, Birmingham, AL, USA Johann Wolfgang Goethe-University, Institute of Anatomy III- 'Cellular and Molecular Anatomy', Frankfurt, Germany University of Birmingham, Institute of Metabolism and Systems Research, Birmingham, UK MRC Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Cambridge, UK Indian Institute of Science, Department of Biochemistry, Bangalore, India School of Medicine, the Southern University of Science and Technology, Shenzhen, China Baylor College of Medicine, Department of Medicine, Houston, TX, USA The University of Kansas Cancer Center, Division of Hematologic Malignancies and Cellular Therapeutics, Kansas City, KS, USA All India Institute of Medical Sciences, Department of Biotechnology, New Delhi, India University of Southampton, Clinical and Experimental Sciences, Faculty of Medicine, UK Johns Hopkins University School of Medicine, Department of Otolaryngology/Head and Neck Surgery, Head and Neck Cancer Research Division, Baltimore, MD, USA University of South Carolina School of Medicine, Department of Pathology, Microbiology, and Immunology, Columbia, SC, USA Washington University School of Medicine, Department of Medicine, Cardiovascular Division,l and John Cochran VA Medical Center, St. Louis, MO, USA Johns Hopkins University, Bloomberg School of Public Health, Biochemistry and Molecular Biology Department, Baltimore, MD, USA Johannes Gutenberg University-Mainz, Institute of Developmental Biology and Neurobiology, Mainz, Germany Heinrich Heine University Düsseldorf, Medical faculty, Institute of Biochemistry and Molecular Biology I, Düsseldorf, Germany The University of Texas MD Anderson Cancer Center, Institute for Applied Cancer Science (IACS), Translational Research to Advance Therapeutics and Innovation in Oncology (TRACTION), Houston, TX, USA Max Planck Institute of Psychiatry, Translational Research in Psychiatry, Munich, Germany University of Vienna, Cell Imaging and Ultrastructure Research (CIUS), Vienna, Austria Karolinska Institutet, Department of Laboratory Medicine, Division of Clinical Microbiology, Stockholm, Sweden Wright State University, Department of Biochemistry & Molecular Biology, Dayton, OH. USA University of Wyoming, College of Health Sciences, Laramie, WY, USA Qingdao Agricultural University, College of Plant Health and Medicine, Qingdao, Shandong, China Ifremer, RBE, Département Ressources, La Tremblade, France University of California, Los Angeles, David Geffen School of Medicine, Department of Human Genetics, Los Angeles, CA, USA Botucatu Medical School, São Paulo State University, Botucatu, SP, Brazil Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France The Ohio State University, College of Veterinary Medicine, Department of Veterinary Biosciences, Columbus, OH, USA Thomas Jefferson University, Department of Orthopaedic Surgery and Graduate Program in Cell Biology and Regenerative Medicine, Philadelphia, PA, USA Josep Carreras Leukaemia Research Institute, Barcelona, Spain Democritus University of Thrace, First Department of Internal Medicine & Laboratory of Molecular Hematology, Alexandroupolis, Greece Redox Signaling and Oxidative Stress group, Danish Cancer Society Research Center, Copenhagen, Denmark University of Padua, Department of Biomedical Sciences, Padua, Italy Middlesex University, Department of Natural Sciences, London, UK INSERM U1065, Centre Méditerranéen de Médecine Moléculaire (C3M), Nice, France; Université de Nice Sophia Antipolis, UFR de Médecine, Nice, France Baylor College of Medicine, Department of Molecular Physiology & Biophysics, Houston, TX, USA Federal University of ABC (UFABC), Center for Natural and Human Sciences (CCNH), Santo André, SP, Brazil University of Campinas (UNICAMP), School of Applied Science, Department of Sport Sciences, Limeira, Brazil University of Barcelona, School of Medicine, Unit of Anatomy, Department of Pathology and Experimental Therapeutics, Barcelona, Spain; L'Hospitalet de Llobregat, Institut d'Investigació Biomèdica de Bellvitge -IDIBELL, Molecular Mechanisms and Experimental Therapy in Oncology Program (oncobell), Barcelona, Spain Kansas City University of Medicine and Biosciences, Department of Basic Science, Kansas City, MO, USA Goethe University Frankfurt, Institute of Pharmaceutical Chemistry, Frankfurt am Main, Germany University of Gdansk, Faculty of Chemistry, Gdansk, Poland Department of Medicine and Surgery, University of Perugia, Perugia Italy Università degli Studi di Catania, Dipartimento di Chirurgia Generale e Specialità Medico-Chirurgiche, Catania, Italy CONICET-Universidad Nacional de Cuyo, Instituto de Histología y Embriología de Mendoza, Mendoza, Argentina INSERM U1151, Institut Necker Enfants-Malades (INEM), Team 8, Université Paris Descartes-Sorbonne-Paris Cité, Paris, France Naples University, Department of Veterinary Medicine and Animal Productions, Naples, Italy University of Würzburg, Institute of Pathology, Würzburg, Germany Kiel University and University Hospital Schleswig-Holstein, Campus Kiel, Institute of Clinical Molecular Biology, Kiel, SH, Germany Georgetown University, Department of Biology, Washington, DC, USA Columbia University, Department of Pathology and Cell Biology, New York, NY, USA University of Illinois, Department of Anesthesiology, Chicago, IL, USA Normandy University, UNICAEN, INSERM, UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), Institute Blood and Brain @Caen-Normandie (BB@C), GIP Cyceron, Caen, FRANCE University of Sherbrooke, Division of Rheumatology, Department of Medicine, Sherbrooke, QC, Canada Section on Eukaryotic DNA Replication, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD,USA University of Seville. School of Pharmacy, Instituto de Biomedicina de Sevilla. Sevilla, Spain University of Cambridge, Cambridge Institute for Medical Research, UK Dementia Research Institute and Department of Medical Genetics, Cambridge, UK Lomonosov Moscow State University, Chemistry Department, Moscow, Russia University Medical Center Eppendorf, Institute for Medical Microbiology, Hamburg, Germany Charles University, Faculty of Medicine in Hradec Kralove, Department of Medical Biology and Genetics, Hradec Kralove, Czech Republic Mannheim University of Applied Sciences, Faculty of Biotechnology, Mannheim, Germany Fondazione IRCCS Istituto Neurologico Carlo Besta, Neuromuscular Disease and Immunology Unit, Milan, Italy; University of Brescia, Unit of Biology and Genetics, Department of Molecular and Translation Medicine, Brescia, Italy Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia University of Ottawa, Department of Cellular and Molecular Medicine, Ottawa, ON, Canada National Research Council, Institute of Food Sciences, Avellino, Italy Stazione Zoologica “Anton Dohrn”, Napoli, Italy University of Calabria, Department of Pharmacy, Health and Nutritional Sciences, Cosenza, Italy N.N. Blokhin National medical research center of oncology, Department of biomarkers and mechanisms of tumor angiogenesis, Moscow, Russia Cancer Research UK Beatson Institute, Glasgow, UK University of Seoul, Department of Life Science, Seoul, Korea University of Pittsburgh Medical Center, Pittsburgh, PA, USA Concordia University, Department of Biology, Montreal, Quebec, Canada; McGill University, Department of Anatomy and Cell Biology, Montreal, Quebec, Canada Ernst-Ruska Centre for Microscopy and Spectroscopy with Electrons (ER-C-3/StructuralBiology), Forschungszentrum Jülich, Jülich, Germany Saitama University, Graduate School of Science and Engineering, Saitama, Japan Rutgers New Jersey Medical School, Department of Cell Biology and Molecular Medicine, Newark, NJ, USA Oregon State University, College of Pharmacy, Department of Pharmaceutical Sciences, Portland, OR, USA Mashhad University of Medical Sciences, Pharmaceutical Technology Institute, Biotechnology Research Center, Mashhad, Iran Boston Children's Hospital and Harvard Medical School, Boston, MA, USA University of South Carolina, Department of Drug Discovery and Biomedical Sciences, Columbia, SC, USA University of Sydney, Northern Clinical School, Kolling Institute of Medical Research, Sydney, NSW, Australia Institute for Research in Biomedicine (IRB Barcelona), Cellular Plasticity and Disease Group, Barcelona, Spain University of Toyama, Sugitani, Toyama, Japan Kyoto University, Graduate School of Agriculture, Division of Applied Life Sciences, Kyoto, Japan The University of Tokyo, Graduate School of Medicine, Department of Biochemistry and Molecular Biology, Tokyo, Japan University of Helsinki and Helsinki University Hospital, Department of Virology, Helsinki, Finland Florida State University, Department of Nutrition, Food and Exercise Sciences, Tallahassee, FL, USA Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Research Group in Critical Disorders (GREPAC), Barcelona, Spain Agricultural Biotechnology Research Institute of Iran (ABRII), Department of Systems Biology, Karaj, Iran University of Minho, School of Medicine, Life and Health Sciences Research Institute (ICVS), Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal CABD/CSIC/Universidad Pablo de Olavide, Departamento de Fisiología, Anatomía y Biología Celular, Sevilla, Spain University of Malaga, Department of Molecular Biology and Biochemistry, Malaga, Spain Imperial College London, Section of Paediatric Infectious Disease & Virology, London, UK INRS-Institut Armand-Frappier, Laval, QC, Canada Weill-Cornell, Englander Institute of Precision Medicine, Department of Radiation Oncology, New York, NY, USA Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal University of Camerino, School of Pharmacy, Experimental Medicine Section, Camerino, Italy University of Glasgow, Institute of Molecular, Cell and Systems Biology, Glasgow, Scotland, United Kingdom Instituto de Biomedicina de Valencia, CSIC, Valencia, Spain Jawaharlal Nehru University, School of Life Sciences, New Delhi, India Institute for Stem Cell Science & Regenerative Medicine (inStem), Bangalore, Karnataka, India University of Maryland School of Medicine, Department of Anesthesiology, Shock, Trauma and Anesthesiology Research Center, Baltimore, MD, USA University of Birmingham, Institute of Biomedical Research, Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, Edgbaston, Birmingham, UK Health Research Institute Germans Trias i Pujol, Innate Immunity Group, Badalona, Barcelona, Spain University of Delhi South Campus, Department of Genetics, New Delhi, India Folkhälsan Research Center, Helsinki, Finland Mayo Clinic, Department of Molecular Medicine, Rochester, MN, USA National Institute of Mental Health and Neurosciences, Department of Neurochemistry, Bengaluru, Karnataka, India Duke University, Department of Molecular Genetics and Microbiology, Durham, NC, USA Goethe University, Institute of Pharmacology and Toxicology, Frankfurt, Germany University of Notre Dame, Department of Biological Sciences, Notre Dame, IN ,USA UCL Queen Square Institute of Neurology, Department of Clinical and Movement Neurosciences, London, UK University Hospital and University of Zürich, Department of Gastroenterology and Hepatology, Zürich, Switzerland University of Calgary, Department of Comparative Biology & Experimental Medicine, Calgary, AB, Canada Department of Biochemistry and Molecular Biology, Institute for Human Infection and Immunity (IHII), University of Texas Medical Branch at Galveston, Galveston, TX, USA Amsterdam University Medical Centers location VUmc, Department of Clinical Genetics, Amsterdam, The Netherlands University of Kaiserslautern, Phytopathology, Kaiserslautern, Germany IRCCS San Raffaele Scientific Institute, Division of Genetics and Cell Biology, Milan, Italy Centro di Riferimento Oncologico, CRO-IRCCS, Molecular Oncology Unit, Aviano, Italy Medical University of Graz, Gottfried Schatz research center, Graz, Austria University Grenoble Alpes and Inserm U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), Grenoble, France Medical University of Innsbruck, Institute for Cell Biology, Innsbruck, Austria Hannover Medical School, Department of Nephrology and Hypertension, Hannover, Germany National Institutes of Health, National Institute of Allergy and Infectious Disease, Vaccine Research Center, Bethesda, MD, USA Ruhr-University Bochum, Department of Molecular Immunology, Bochum, Germany German Center for Neurodegenerative Diseases, DZNE, Bonn, Germany and Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Bonn, Bonn, Germany Reseach Center Borstel, Leibniz Lung Center, Priority Research Area Infections, Junior Research Group Coinfection, Borstel, Germany Johannes Kepler University Linz, Institute of Biophysics, Linz, Austria Instituto de Investigaciones en Ingeniería Genética y Biología Molecular Dr. Héctor N. Torres, Laboratorio de Señalización y Mecanismos Adaptativos en Tripanosomátidos, Buenos Aires, Argentina; Universidad de Buenos Aires, Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Buenos Aires, Argentina Instituto de Investigaciones en Ingeniería Genética y Biología Molecular Dr. Héctor N. Torres, Laboratorio de señalización y mecanismos adaptativos en Tripanosomátidos, Buenos Aires, Argentina; Universidad de Buenos Aires, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Buenos Aires, Argentina Mayo Clinic, Department of Biochemistry and Molecular Biology, Division of Gastroenterology and Hepatology, Rochester, MN, USA Technische Universität Dresden, Institute for Physiological Chemistry, Dresden, Germany University of Wuerzburg, Department of Vegetative Physiology, Wuerzburg, Germany University of Natural Resources and Life Sciences, Department of Applied Genetics and Cell Biology, Vienna, Austria Mayo Clinic, Division of Gastroenterology and Hepatology, Rochester, MN, USA University of Luxembourg, Luxembourg Centre for Systems Biomedicine (LCSB), Esch-sur-Alzette, Luxembourg Forschungszentrum Jülich, Institute of Biological Information Processing, IBI-7 (Structural Biochemistry), Jülich, Germany University of Campania L. Vanvitelli, Dipartimento di Scienze Mediche Traslazionali, Naples, Italy Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, Italy; IRCCS Neuromed, Pozzilli (IS), Italy Rutgers Biomedical and Health Sciences, Rutgers University, Robert Wood Johnson Medical School, Department of Pharmacology, New Brunswick , NJ, USA National Research Council, Institute of Molecular Genetics, Pavia, Italy Helmholtz Centre for Infection Research, Braunschweig, Germany Albert Einstein College of Medicine, Department of Developmental and Molecular Biology, Bronx, NY, USA; Albert Einstein College of Medicine, Institute for Aging Studies, Bronx, NY, USA Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain; Departament de Bioquímica i Biomedicina Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain Rice University, Department of Bioengineering, Houston, TX, USA University of Illinois at Chicago, College of Medicine, Department of Biochemistry and Molecular Genetics, Chicago, IL, USA University of Oslo, Centre for Molecular Medicine Norway (NCMM), Oslo, Norway Université de Pau et des Pays de l’Adour, E2S UPPA, INRAE, UMR1419 Nutrition Métabolisme et Aquaculture, F-64310 Saint-Pée-sur-Nivelle, France Cedars-Sinai Medical Center, Department of Medicine, Division of Digestive and Liver Diseases, Los Angeles, CA, USA Pennsylvania State University, Department of Biochemistry and Molecular Biology, University Park, PA, USA Alpert Medical School of Brown University/Rhode Island Hospital, Division of Cardiothoracic Surgery, Providence, RI, USA Iowa State University, Animal Science Department, Ames, IA, USA Dokuz Eylul University, Izmir International Biomedicine and Genome Institute, Izmir, Turkey University of Alberta, Department of Laboratory Medicine and Pathology, Edmonton, AB, Canada University of Rochester Medical Center, Microbiology and Immunology, Rochester, NY, USA Johns Hopkins University School of Medicine, Department of Cell Biology, Baltimore, MD, USA Indian Institute of Science, Department of Microbiology and Cell Biology, Bangalore, KA, India Shenzhen University Health Science Center, School of Dentistry, Shenzhen, Guangdong Province, China University of Alabama at Birmingham, Department of Pharmacology & Toxicology, Birmingham, AL, USA University of Washington, Department of Medicine, Seattle, WA, USA; VA Puget Sound Health Care System, Seattle, WA, USA Soochow University, Institutes for Translational Medicine, Suzhou, Jiangsu, China Freie Universitaet Berlin, Department of Veterinary Medicine, Institute of Veterinary Biochemistry, Berlin, Germany Johns Hopkins University, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA University of Pennsylvania, Abramson Cancer Center, Department of Medicine, PA, USA Division of Stem Cell and Gene Therapy Research, Institute of Nuclear Medicine & Allied Sciences (INMAS), Defence Research and Development Organization (DRDO), Timar Pur, New Delhi, India Thomas Jefferson University, Center for Translational Medicine, Philadelphia, PA, USA Women and Infants Hospital of Rhode Island-Warren Alpert Medical School of Brown University, Department of Pediatrics, Providence, RI, USA University of Macau, Faculty of Health Sciences, Macau, China The University of Hong Kong, School of Chinese Medicine, Hong Kong, China Nanjing Agricultural University, College of Animal Science and Technology, Nanjing, Jiangsu, China Shanghai Jiao Tong University School of Medicine, Department of Hypertension, Ruijin Hospital, Shanghai, China Total Toxicology Labs, Southfield, MI, USA Soochow University, College of Pharmaceutical Sciences, Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Suzhou, China Fralin Biomedical Research Institute at VTC, Roanoke, VA, USA Indiana University School of Medicine, Department of Pediatrics, Indianapolis, IN, USA Van Andel Institute, Center for Epigenetics, Grand Rapids, MI, USA Fudan University, Zhongshan Hospital, Liver Cancer Institute, Department of Liver Surgery & Transplantation, Shanghai, China Juntendo University Graduate School of Medicine, Department of Treatment and Research in Multiple Sclerosis and Neuro-intractable Disease, Bunkyo-ku, Tokyo, Japan National Chung-Hsing University, Institute of Biomedical Sciences, Taichung City, Taiwan Jikei University School of Medicine, Research Center for Medical Sciences, Division of Gene Therapy, Tokyo, Japan Tokyo Medical and Dental University, Department of Pathological Cell Biology, Tokyo, Japan Tohoku University, Graduate School of Agricultural Science, Sendai, Japan Geisel School of Medicine at Dartmouth, Department of Biochemistry and Cell Biology, Hanover, NH, USA Kobe University Graduate School of Medicine, Center for Infectious Diseases, Division of Infectious Disease Control, Kobe, Japan MACS - Agharkar Research Institute, Developmental Biology Group, Pune, India; Savitribai Phule Pune University, Ganeshkhind, Pune, Maharashtra, India Mayo Clinic College of Medicine, Department of Experimental Pathology, Rochester, MN, USA National Sun Yat-sen University, Institute of Biopharmaceutical Sciences, Kaohsiung, Taiwan Huazhong University of Science and Technology, College of Life Science and Technology, Key Laboratory of Molecular Biophysics of Ministry of Education,Wuhan, Hubei, China University of Calgary, Cumming School of Medicine, Departments of Medical Genetics and Biochemistry & Molecular Biology, Calgary, Alberta, Canada Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBER on Neurodegenerative diseases (CIBERNED), E-08003 Barcelona, Spain Achucarro Basque Center for Neuroscience, Department of Neurosciences, University of the Basque Country EHU/UPV, Leioa, Bizkaia, Spain Universidad de la República, Facultad de Agronomía, Departamento de Biología Vegetal, Montevideo, Uruguay National Institutes of Health, NIEHS, RTP, Durham, NC, USA David Geffen School of Medicine at University of California, Los Angeles, Department of Medicine, Division of Dermatology, Los Angeles, CA, USA University of Bern, Institute of Pharmacology, Bern, Switzerland; Sechenov University, Department of Clinical Immunology and Allergology, Moscow, Russia INSERM UMR1163, Laboratory of Epithelial Biology and Disease, Imagine Institute, Paris Descartes University, Sorbonne Paris Cité, Hôpital Necker-Enfants Malades, Paris, France Boston University School of Medicine, Division of Hematology & Medical Oncology, Department of Pharmacology & Experimental Therapeutics, Boston, MA, USA Wayne State University School of Medicine, Department of Ophthalmology, Visual and Anatomical Sciences, Detroit, MI, USA University of Pittsburgh, Department of Pharmacology & Chemical Biology, Pittsburgh, PA, USA Post Graduate Institute of Medical Education and Research (PGIMER), Department of Urology, Chandigarh, India Biomedical Research Institute of New Mexico, VA Healthcare System, Albuquerque, NM, USA CSIR-National Physical Laboratory, Dr. K. S. Krishnan Marg, New Delhi, India University of Pittsburgh School of Medicine, Departments of Ophthalmology, Cell Biology, and Developmental Biology, Pittsburgh, PA, USA Sanjay Gandhi Postgraduate Institute of Medical Sciences, Department of Endocrinology, Lucknow, India North Dakota State University, Department of Chemistry and Biochemistry, Fargo, ND, USA National Jewish Health, Department of Medicine, Division of Allergy & Immunology, and Division of Pulmonary and Critical Care Medicine, Denver, CO, USA Masaryk University, Faculty of Medicine, Department of Biology, Brno, Czech Republic Washington State University, Institute of Biological Chemistry, Pullman, WA, USA Edinburgh Cancer Research UK Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK Dong-A University, College of Medicine, Department of Molecular Neuroscience, Peripheral Neuropathy Research Center, Busan, Korea Lomonosov Moscow State University, Department of Biology, Moscow, Russia Indian Institute of Technology Indore, Discipline of Biosciences and Biomedical Engineering, Indore, Madhya Pradesh, India Shandong University, School of public health, Department of Toxicology and nutrition. Jinan, Shandong, China Korea University, Department of Life Sciences, Seoul, Korea Guangzhou University of Chinese Medicine, Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou, China; Hong Kong Baptist University, School of Chinese Medicine, Mr. and Mrs. Ko Chi Ming Centre for Parkinson's Disease Research, Hong Kong SAR, China University of Colorado Anschutz Medical Campus, Division of Cardiology, Aurora, CO, USA Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, Hubei, China Massachusetts General Hospital and Harvard Medical School, Department of Medicine, Endocrine Division, Boston, MA, USA University of Guelph, Department of Food Science, Guelph, Canada University of California, San Diego, La Jolla, CA, USA; Rady Children’s Hospital San Diego, San Diego, CA, USA Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences, Bengaluru-560029, Karnataka, India University of Kentucky, Department of Toxicology and Cancer Biology, Lexington, KY, USA Institute of Molecular Biology and Pathology, National Research Council (CNR), Rome, Italy; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Laboratory of Cell Signaling, Rome, Italy University of Western Ontario, Department of Physiology and Pharmacology, London, Ontario, Canada University of Oslo, Department of Neuro-/Pathology, Oslo, Norway University of Bonn, Department of Pharmaceutical & Cellbiological Chemistry, Bonn, Germany Biomedical Research Foundation of the Academy of Athens, Laboratory of Neurodegenerative Diseases, Athens, Greece; National and Kapodistrian University of Athens Medical School, First Department of Neurology, Athens, Greece University of California, Irvine, Department of Psychiatry and Human Behavior, Irvine, CA, USA Friedrich-Alexander-Universität Erlangen-Nürnberg, Department of Immune Modulation, University Hospital Erlangen, Erlangen, Germany Oslo University Hospital, Institute for Cancer Research, Department of Molecular Cell Biology, Montebello, Oslo, Norway Technische Universität Dresden, Center for Regenerative Therapies Dresden, Dresden, Germany Jožef Stefan Institute, Department of Biochemistry and Molecular and Structural Biology, Ljubljana, Slovenia University Medical Center Hamburg-Eppendorf, Children's Hospital, University Children's Research@Kinder-UKE, Hamburg, Germany Heinrich-Heine-University, Medical Faculty, Institute of Molecular Medicine I, Düsseldorf, Germany IRCCS Fondazione Santa Lucia, Rome, Italy The Ohio State University, Department of Cancer Biology and Genetics, Columbus, OH, USA University of California San Diego, UCSD Moores Cancer Center, La Jolla, CA, USA Peking Union Medical College and Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Department of Critical Care Medicine, Beijing, China Instituto Oswaldo Cruz, LITEB/IOC, Fundação Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil Case Western Reserve University School of Medicine, Departments of Medicine and Pathology, Cleveland, OH USA Rutgers University, New Jersey Medical School and Public Health Research Institute, Newark, NJ, USA University of Madras, Department of Biochemistry, Guindy Campus, Chennai, India Kolling Institute, Department of Neurogenetics, University of Sydney and Royal North Shore Hospital, St Leonards NSW, Australia Hangzhou Normal University, Affiliated Hospital of Hangzhou Normal University, College of Medicine, Holistic Integrative Pharmacy Institutes and Comprehensive Cancer Diagnosis and Treatment Center, Hangzhou, Zhejiang, China Iowa State University, Department of Kinesiology, Ames, IA, USA University of Nebraska Lincoln, Department of Agronomy and Horticulture, Center for Plant Science Innovation, Lincoln, NE, USA University of Illinois at Chicago, Department of Medicine, Chicago, IL, USA Shanghai Jiao Tong University, School of Medicine, Ren Ji Hospital, Center for Reproductive Medicine, Shanghai, China Wuhan University, College of Life Sciences, Wuhan, Hubei, China Zhejiang University, School of Medicine, Department of Biochemistry, Hangzhou, Zhejiang, China Cancer Institute of the Second Affiliated Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China University of Tennessee Health Science Center, Department of Physiology, Memphis, TN, USA Experimental Physiopathology, Department of Sciences/Experimental Physiopatholgy, Medical School, University of São Paulo, Brazil Swedish University of Agricultural Sciences, The Linnean Centre of Plant Biology in Uppsala, Department of Plant Biology, Uppsala, Sweden University of Pennsylvania, Perelman School of Medicine, Department of Medicine, Philadelphia, PA, USA University of Missouri, Division of Animal Science and Department of Obstetrics, Gynecology & Women's Health, Columbia, MO, USA Tokai University School of Medicine, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Isehara, Kanagawa, Japan York University, Department of Biology, Toronto, Canada University of Utah, Department of Nutrition and Integrative Physiology; Division of Endocrinology, Metabolism, and Diabetes; Investigator, Molecular Medicine Program, Salt Lake City, UT, USA Hong Kong Baptist University, Faculty of Science, Department of Biology, Hong Kong, China; Hong Kong Baptist University, Golden Meditech Centre for NeuroRegeneration Sciences, Hong Kong, China Ohio Musculoskeletal and Neurological Institute (OMNI) and Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA Istituto Superiore di Sanità, Department of Oncology and Molecular Medicine, Rome, Italy; Fondazione Umberto Veronesi, Milan, Italy Charité University Medicine Berlin, Department of Hepatology & Gastroenterology, Berlin, Germany The University of Texas Health Science Center at Houston, McGovern Medical School, Department of Internal Medicine, Cardiology, Houston, TX, USA Chengdu Medical College, Department of Anatomy and Histology and Embryology, Development and Regeneration Key Lab of Sichuan Province, Chengdu, China University of Glasgow, Institute of Cancer Sciences, Glasgow, UK Penn State University College of Medicine, Department of Pediatrics, Hershey, PA, USA VIT University, School of Biosciences and Technology, Vellore, Tamilnadu, India The Chinese University of Hong Kong, School of Biomedical Sciences, Hong Kong, China; The Chinese University of Hong Kong, Department of Obstetrics and Gynecology, Hong Kong, China Inserm Unit 1195 - University of Paris Saclay, Le Kremlin-Bicetre, France Tokyo Medical and Dental University (TMDU), Institute of Biomaterials and Bioengineering, Tokyo, Japan National Neuroscience Institute, Duke NUS Medical School, Singapore Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, Hubei, China The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST), Wuhan University, School and Hospital of Stomatology, Department of Oral Medicine, Wuhan, Hubei, China Kyoto Prefectural University of Medicine, Department of Anatomy and Neurobiology, Kyoto, Japan RIKEN Center for Brain Science, Laboratory for Protein Conformation Diseases, Wako, Saitama, Japan Hubei University of Technology, National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Wuhan, China State Key Laboratory of Membrane Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing, China Juntendo University Graduate School of Medicine, Department of Cellular and Molecular Neuropathology, Tokyo, Japan Harvard Medical School, Massachusetts General Hospital, Cutaneous Biology Research Center, Charlestown, MA, USA University Medicine Goettingen, Neurology, Department of Translational Neurodegeneration, Center for Biostructural Imaging of Neurodegeneration (BIN), Goettingen, Germany Foundation for Research and Technology-Hellas, Institute of Molecular Biology and Biotechnology, Heraklion, Crete, Greece; University of Crete, Medical School, Heraklion, Crete, Greece Duke University, Department of Medicine; Duke University, Department of Molecular Genetics and Microbiology; Duke University, Department of Immunology, Durham, NC, USA; Geriatric Research, Education, and Clinical Center, VA Health Care Center, Durham, NC, USA University of North Carolina, Department of Pathology, Chapel Hill, NC, USA Nasonova Research Institute of Rheumatology, Moscow, Russia Cardiff University, Division of Cancer and Genetics, Heath Park Way, Cardiff, UK Goethe-University, Faculty of Medicine, Department of Clinical Pharmacology, Frankfurt, Germany INSERM U955, Team “Virus Hepatology Cancers”, Créteil, France; Université Paris-Est, UMR S955, UPEC, Créteil, France Chulalongkorn University, Faculty of Allied Health Sciences, Age-Related Inflammation and Degeneration Research Unit, Department of Clinical Chemistry, Bangkok, Thailand University of Liverpool, Department of Cellular and Molecular Physiology, Liverpool, UK Centro de Investigaciones Biológicas Margarita Salas, CIB-CSIC, Madrid, Spain Carl von Ossietzky University Oldenburg, School of Medicine and Health Sciences, Department for Neuroscience, Oldenburg, Germany University of Genova, Department of Internal Medicine, Genova, Italy University of Kansas Medical Center, Department of Otolaryngology, Kansas City, KS, USA University of Nebraska Medical Center, Departments of Internal Medicine and Biochemistry and Molecular Biology, Omaha, NE, USA University of Colorado School of Medicine, Department of Pharmacology, Aurora, CO, USA CSIR-Institute of Genomics and Integrative Biology, South Campus, New Delhi, India Hannover Medical School, Institute for Molecular and Therapeutic Strategies (IMTTS), Hannover, Germany University Medical Center Göttingen, Institute of Cellular Biochemistry, Göttingen, Germany South China Agricultural University, Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding/Guangdong Provincial Sericulture and Mulberry Engineering Research Center, College of Animal Science, Guangzhou, China University Hospital of Bonn, Institute of Reconstructive Neurobiology, Bonn, Germany University of Antwerp, Department of Biomedical Sciences, Peripheral Neuropathy Research Group, Antwerp, Belgium Concordia University, Department of Biology, Montreal, Quebec, Canada Wayne State University School of Medicine, Department of Pharmacology, Detroit, MI, USA University of Oviedo, Department of Functional Biology, Physiology, Oviedo, Asturias, Spain Zhejiang University, Life Sciences Institute and Innovation Center for Cell Signaling Network, Hangzhou, China Northwestern University, Feinberg School of Medicine, Department of Pathology, Chicago, IL, USA Centre de Recherche des Cordeliers, INSERM, Université de Paris, Sorbonne Université, Paris, France Nagoya University Graduate School of Medicine, Department of Pathology and Biological Responses, Nagoya, Japan University of Belgrade, Faculty of Medicine, Institute of Microbiology and Immunology, Belgrade, Serbia University Federico II of Naples, Department of Molecular Medicine and Medical Biotechnology, Naples, Italy Universidade Federal do Rio de Janeiro, Institute of Biophysics Carlos Chagas Filho, Immunobiology Program, Rio de Janeiro, RJ, Brazil National and Kapodistrian University of Athens, Faculty of Biology, Department of Cell Biology and Biophysics, Panepistimiopolis, Athens, Greece Medical University of South Carolina, Department of Medicine, Division of Rheumatology & Immunology, Charleston, SC, USA University of Bern, Institute of Pathology, Division of Experimental Pathology, Bern, Switzerland University of Hong Kong, Cardiology Division, Department of Medicine, Hong Kong, China University of Southampton , Biological Sciences, Faculty of Environmental and Life Sciences, Highfield, Southampton, UK Universite de Moncton, Department of Chemistry and Biochemistry, Moncton, NB, Canada University of Birmingham, Institute of Cancer and Genomic Sciences, Birmingham, UK Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY, USA Komarov Botanical Institute RAS, Laboratory of Molecular and Ecological Physiology, Saint Petersburg, Russian Federation Nottingham Trent University, School of Science and Technology, Nottingham, UK University of Oxford, John Radcliffe Hospital, Translational Gastroenterology Unit and Department of Paediatrics, Oxford, and Oxford NIHR Biomedical Research Centre, Oxford, UK Institute of Psychiatry and Neurology, First Department of Neurology, Warsaw, Poland Sechenov First Moscow State Medical University, Institute for Regenerative Medicine, Moscow, Russia Mie University, Graduate School of Bioresources, Tsu, Japan University of Osnabrück, Department of Biology/Chemistry, and Center of Cellular Nanoanalytics Osnabrück (CellNanOs), Osnabrück, Germany Nagoya City University Graduate School of Medical Sciences, Department of Nephro-urology, Nagoya, Aichi, Japan University of Tübingen, Center for Plant Molecular Biology (ZMBP), Tübingen, Germany University of Milan, Department of Biosciences, Milan, Italy University of Buenos Aires, Institute of Biochemistry and Molecular Medicine, Pathophysiology Department, School of Pharmacy and Biochemistry, CONICET, Buenos Aires, Argentina University of Oxford, Nuffield Department of Clinical Neurosciences, Oxford, UK Karolinska Institute, Department of Physiology and Pharmacology, Stockholm, Sweden University of Murcia, Department of Biochemistry, Molecular Biology B and Immunology; Biomedical Research Institute of Murcia (IMIB-Arrixaca), Unit of Autophagy, Immunity and Cancer, Murcia, Spain Fundación Instituto Leloir and IIBBA, CONICET, Buenos Aires, Argentina; Laboratorio de Glicobiología Celular y Genética Aplicada de Levaduras, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina Instituto de Investigaciones Biomedicas Alberto Sols (CSIC-UAM), Madrid, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERdem), Instituto de Salud Carlos III, Madrid, Spain Zhejiang University, School of Medicine, Department of Microbiology and Parasitology, Hangzhou, China Vanderbilt University School of Medicine, Department of Pathology, Microbiology and Immunology, Nashville, TN, USA Center of Translational Immunlogy, University Medical Center Utrecht, Utrecht, The Netherlands Goethe University, Institute for Experimental Cancer Research in Pediatrics, Frankfurt am Main, Germany University Hospitals Leuven, Department of Neurology, Leuven, Belgium; KU Leuven, Department of Neurosciences, Leuven, Belgium Laboratory of Immunosenescence and Stem Cell Metabolism, Department of Oncology, Ludwig Cancer Institute, University of Lausanne, 1066 Epalinges, Switzerland Scientific Institute, IRCCS E. Medea, Laboratory of Molecular Biology, Bosisio Parini, Lecco, Italy Instituto de Investigaciones Biomedicas “Alberto Sols” (CSIC-UAM) and CIBERER (CIBER, ISCiii), Madrid, Spain Harvard Medical School, Ophthalmology, Boston, MA, USA Universitätsklinikum Essen, Institute for Cell Biology (Cancer Research), Essen, Germany University of Groningen, University Medical Center Groningen, Department of Hematology, Groningen, The Netherlands Tuscia University, Department of Ecological and Biological Sciences (DEB), Viterbo, Italy EA 3842, Limoges University, Faculty of Medicine, Limoges cedex, France Biomedical Research Foundation, Academy of Athens, Center of Clinical, Experimental Surgery and Translational Research, Athens, Greece Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, Université Paul Sabatier, Toulouse, France University of Pittsburgh, Department of Pathology, Pittsburgh, PA, USA Washington University in St. Louis, Department of Medicine, St. Louis, MO, USA Service of Endocrinology, University Hospital Doctor Peset, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region (FISABIO)-Department of Physiology, University of Valencia, Valencia, Spain University of Montpellier, UMR 5235, Montpellier, France Universidade NOVA de Lisboa, CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisboa, Portugal University of Helsinki, Institute of Biotechnology, Electron Microscopy Unit, Helsinki, Finland Vall d'Hebron Research Institute (VHIR)-Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED)-Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain Institute of Biomedicine of Valencia, Spanish Research Council (CSIC), Valencia, Spain University Hospital La Paz Research Institute (IdiPAZ), Cancer and Human Molecular Genetics Area Oto-Neurosurgery Research Group, Madrid, Spain University of Toulouse, Institute of Metabolic and cardiovascular Diseases, INSERM UMR 1048, Toulouse, France Università Cattolica del Sacro Cuore, Department of Life Science and Public Health Section of Histology and Embryology, Rome, Italy Italian Institute for Genomic Medicine (IIGM), Candiolo (TO), Italy; Candiolo Cancer Institute, FPO-IRCCS, Candiolo (TO), Italy Simon Fraser University, Department of Chemistry, Department of Molecular Biology and Biochemistry, Burnaby, British Columbia, Canada Institute for Systems Analysis and Computer Science “A. Ruberti”, National Research Council (IASI–CNR), IRCCS Fondazione Santa Lucia, Rome, Italy Eurac Research, Institute for Biomedicine, Bolzano, Italy Rheinische Friedrich-Wilhelms-Universität, Institut für Biochemie und Molekularbiologie (IBMB), Bonn, Germany University of Oxford, Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics, Oxford, UK Fukushima Medical University, School of Medicine, Department of Anatomy and Histology, Fukushima, Japan University of California, Los Angeles, Department of Integrative Biology and Physiology, Los Angeles, CA, USA The University of Queensland, School of Chemistry and Molecular Biosciences and Australian Infectious Diseases Research Centre, St. Lucia, Brisbane, Queensland, Australia Babraham Institute, Cambridge, UK University of Bonn, Department of Neurology, Molecular Cell Biology Unit, Bonn, Germany Universidad Autónoma de Madrid, Centro de Biología Molecular Severo Ochoa (CSIC-UAM & CIBERNED), Madrid, Spain St Jude Children's Research Hospital, Department of Pathology, Memphis, TN, USA Chang Gung University College of Medicine and Chang Gung Memorial Hospital, Department of Cardiology, Taoyuan City, Taiwan; National Health Research Institutes, Institute of Cellular and System Medicine, Zhunan, Taiwan China Pharmaceutical University, School of Life Science and Technology, Nanjing, Jiangsu, China University of California Los Angeles, School of Dentistry, Division of Oral Biology and Medicine, Los Angeles, CA, USA Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China University of Michigan, Department of Internal Medicine, Division of Hematology and Oncology, Ann Arbor, MI, USA Shanghai Ninth People's Hospital, National Clinical Research Center for Oral Disease, Shanghai Jiao Tong Univeristy, School of Medicine, Shanghai, China Texas A&M College of Dentistry, Department of Endodontics, Dallas, TX, USA Third Military Medical University of China, Xinqiao Hospital, Institute of Respiratory Diseases, Chongqing, China Soochow University, Center for Circadian Clocks; School of Biology & Basic Medical Sciences, Medical College, Suzhou, Jiangsu, China CAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology (NCNST), Zhongguancun, Beijing, China China Agricultural University, College of Biological Sciences, State Key Laboratory of Agro-Biotechnology and MOA Key Laboratory of Soil Microbiology, Beijing, China Soochow University, Hematology Center of Cyrus Tang Hematology Institute, School of Medicine, Suzhou, China China Academy of Chinese Medical Sciences, Artemisinin Research Center and the Institute of Chinese Materia Medica, Beijing, China Shanxi Agricultural University, Shanxi Key Laboratory of Ecological Animal Science and Environmental Veterinary Medicine, Taigu, Shanxi, China Sichuan University, West China School of Basic Medical Sciences & Forensic Medicine, Chengdu, China Hunan Key Laboratory of Medical Epigenomics, Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China The Chinese University of Hong Kong, School of Public Health and Primary Care, Hong Kong, China Fourth Military Medical University, College of Stomatology, Department of Oral Anatomy and Physiology and TMD, Xi'an, China The First Affiliated Hospital, Jinan University, Guangzhou, China Huazhong Agricultural University, College of Horticulture and Forestry Science, Key Laboratory of Horticultural Plant Biology (Ministry of Education), Wuhan, China National University of Singapore, Department of Medicine, Cardiovascular Research Institute, Singapore Feinstein Institutes for Medical Research, Center for Immunology and Inflammation, Manhasset, NY, USA University of Kentucky, Department of Ophthalmology and Visual Sciences, Lexington, KY, USA Zhujiang Hospital of Southern Medical University, Department of Neurology, Guangzhou, Guangdong Province, China Cleveland Clinic, Department of Cardiovascular Medicine/Heart and Vascular Institute, Cleveland, OH, USA Diabetes and Metabolism Research Institute, Department of Molecular & Cellular Endocrinology; City of Hope Medical Center, Beckman Research Institute, Comprehensive Cancer Center, Duarte, CA, USA Xuzhou Medical University, Department of Anesthesiology, Xuzhou, Jiangsu, China Stanford University School of Medicine, Department of Neurosurgery, Palo Alto, CA, USA University of South Dakota, Division of Basic Biomedical Sciences, Vermillion, SD, USA Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL, USA Department of Neurology, University of Michigan School of Medicine, Ann Arbor, MI, USA Kaohsiung Medical University, School of Dentistry, College of Dental Medicine, Kaohsiung, Taiwan University of Southampton, Faculty of Environmental and Life Sciences, Biological Sciences, and the Institute for Life Sciences, Southampton, UK German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; Max-Planck-Institute for Metabolism Research, Hamburg Outstation, Hamburg, Germany; Shanghai Qiangrui Biotech Co., Ltd., Fengxian District, Shanghai, China Nanjing Agricultural University, College of Horticulture, Weigang NO. 1, Nanjing, China Saint Louis University, Department of Biology, Saint Louis, MO, USA Air Force Medical University, Xijing Hospital and School of Basic Medicine, Department of Pathology, State Key Laboratory of Cancer Biology, Xi'an, China Affiliated Union Hospital of Fujian Medical University, Fuzhou, Fujian, China Wenzhou Medical University, Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wenzhou, China Queen Mary University, Blizard Institute, Flow Cytometry Core Facility, London, UK Juntendo University Graduate School of Medicine, Department of Metabolism & Endocrinology, Bunkyo-ku, Tokyo, Japan Chiba University Graduate School of Medicine, Department of General Medical Science, Chiba, Japan University of Cincinnati College of Medicine, Cincinnati Children’s Research Foundation, Division of Pulmonary Biology, Department of Pediatrics, Cincinnati, OH, USA Department of Biological Sciences, University of Denver, Denver, CO, USA University of Pennsylvania, Department of Anesthesiology, Philadelphia, PA, USA Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China Washington University School of Medicine, Department of Neurology, St. Louis, MO, USA University of Bonn, Pharmaceutical Institute, Section Pharmacology and Toxicology, Bonn, Germany University Hospital RWTH Aachen, Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), Aachen, Germany Univ of Pittsburgh and Pittsburgh VA HealthSystem, Department of Pathology, Pittsburgh, PA, USA Spencer Center for Vision Research, Byers Eye Institute, Stanford University School of Medicine, Stanford, CA, USA Georg August University Göttingen, Institute of Microbiology and Genetics, Department of Genetics of Eukaryotic Microorganisms, Göttingen, Germany Harvard Medical School and Brigham & Women's Hospital, Precision Neurology Program & APDA Center for Advanced Parkinson Research, Boston, MA, USA University of Nottingham, School of Life Sciences, Queen's Medical Centre, Nottingham, UK Scripps Research Institute, La Jolla, CA, USA Amsterdam University Medical Centers, Location AMC, Tytgat Institute for Intestinal Research, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands Quadram Institute Bioscience, Norwich Research Park, Norwich, Norfolk, UK University of Edinburgh, MRC Institute of Genetics and Molecular Medicine, Scotland, UK Heinrich-Heine-Universität Düsseldorf Institut für Physikalische Biologie, Düsseldorf, Germany Queensland University of Technology, Centre for Tropical Crops and Biocommodities, Science and Engineering Faculty, Brisbane, Queensland, Australia Royal Holloway University of London, Centre for Biomedical Sciences, Egham, Surrey, UK National Institutes of Health, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA University of Nebraska-Lincoln, Department of Plant Pathology, Lincoln, NE, USA Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Stem Cell Biology, Erlangen, Germany University of Toronto, Faculty of Medicine, Department of Immunology, Toronto, ON, Canada Department of Obstetrics and Gynecology, Weill Cornell Medicine, 1300 York Avenue, Box 35, New York, NY, United States. MFP CNRS UMR 5234, University of Bordeaux, Bordeaux, France Institut Pasteur, Membrane Biochemistry and Transport, Paris, France National University of Singapore, Yong Loo Lin School of Medicine, Healthy Longevity Translational Research Program, Singapore; National University Health System, Centre for Healthy Longevity, Singapore School of Medicine, Shenzhen University, Shenzhen, China Kanazawa University, WPI-Nano Life Science Institute (WPI-nanoLSI), Kanazawa, Ishikawa, Japan University of Zurich, Institute of Experimental Immunology, Switzerland, Zurich Southwest Medical University, Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica, Jiangyang District, Luzhou, China University of California San Diego, Department of Neurosciences, La Jolla, CA, USA University of Maryland School of Medicine, Center for Shock, Trauma and Anesthesiology Research (STAR), Departments of Anesthesiology, Anatomy & Neurobiology, Baltimore, MD, USA NHRI, Institute of Cellular and System Medicine, Zhunan, Taiwan University of North Dakota, Biology School of Medicine and Health Sciences, Department of Biomedical Sciences, Grand Forks, ND, USA Soochow University, Department of Pathogenic Biology, Suzhou, Jiangsu Province, China First Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Center for Translational Medicine, Xi'an, Shaanxi, China Zhejiang Provincial People's Hospital, Department of Endocrinology, Hangzhou, China University of Kansas, Department of Molecular Biosciences, and University of Kansas Medical School, University of Kansas Cancer Center, Department of Radiation Oncology, Lawrence, KS, USA Zhejiang University School of Medicine, Department of Toxicology of School of Public Health, and Department of Gynecologic Oncology of Women's Hospital, Hangzhou,China The Broad Institute of Harvard and MIT, Massachusetts General Hospital, Harvard Medical School, Department of Molecular Biology, Cambridge, MA, USA Zhejiang University, Department of Biochemistry in School of Medicine, Hangzhou, Zhejiang Province, China Shenzhen University, College of Medicine, Shenzhen, Guangdong, China The University of Hong Kong, Department of Anesthesiology, Queen Mary Hospital, Hong Kong, China Wuhan University, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan, China Shanghai Jiao Tong University School of Medicine, Ruijin Hospital, Department of Otolaryngology & Head and Neck Surgery, Shanghai, China Friedrich-Alexander University Erlangen-Nürnberg, University Hospital Erlangen, Department of Molecular Neurology, Erlangen Germany Research Department, National Neuroscience Institute, Singapore Southern University of Science and Technology, Department of Biology, Shenzhen, China Sichuan University, West China Hospital, Centre of Geriatrics and Gerontology, Chengdu, China University of Electronic Science and Technology of China, School of Medicine, Chengdu, China; Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Department of Pharmacy, Chengdu, Sichuan, China Wenzhou Medical University, School of Pharmaceutical Sciences, Wenzhou, China Queensland University of Technology, Institute of Health and Biomedical Innovation, Kelvin Grove, Brisbane, Queensland, Australia Sun Yat-sen University, School of Life Sciences, Guangdong Provincial Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, Guangzhou, China South China Agricultural University, College of Veterinary Medicine, Guangzhou, Guangdong, China Southwest Hospital, Third Military Medical University (Army Medical University), Key Laboratory of Hepatobiliary and Pancreatic Surgery, Institute of Hepatobiliary Surgery, Chongqing, China University of Alabama at Birmingham, Division of Cardiovascular Disease, Department of Medicine, Birmingham, AL, USA Georgia State University, The Center for Molecular and Translation Medicine, Atlanta, GA, USA Biomedical Research Foundation of the Academy of Athens (BRFAA), Center of Clinical, Experimental Surgery, & Translational Research, Athens, Greece Shanghai Sixth People's Hospital, Department of Cardiovascular Medicine, and Shanghai Jiaotong University School of Medicine, Shanghai Institute of Immunology, Shanghai, China Institute of Neurosciences and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China Jinan University, College of Life Science and Technology, Guangzhou, China Yangzhou University, College of Veterinary Medicine, Jiangsu Province, China Kyoto Institute of Technology, Department of Applied Biology, Matsugasaki, Sakyo-ku, Kyoto, Japan Ehime University Graduate School of Medicine, Department of Cardiology, Pulmonology, Hypertension & Nephrology, Shitsukawa, Toon, Ehime, Japan Columbia University, Department of Neurology, and Pathology and Cell Biology, New York, NY, USA Juntendo University School of Medicine, Department of Gastroenterology, Bunkyo-ku, Tokyo, Japan Indiana University School of Medicine, Department of Pathology and Laboratory Medicine, Indianapolis, IN, USA National Cheng Kung University, College of Medicine, Department of Physiology, Tainan City, Taiwan University of Virginia, Departments of Medicine, Pharmacology, Molecular Physiology & Biological Physics, Center for Skeletal Muscle Research at Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, VA, USA Asahikawa Medical University, Department of Ophthalmology, Hokkaido, Japan Hong Kong Baptist University, Mr. and Mrs. Ko Chi Ming Centre for Parkinson's Disease Research, School of Chinese Medicine, Hong Kong, China Nathan Kline Institute for Psychiatric Research, Center for Dementia Research, Orangeburg, NY; New York University Langone Health, Department of Psychiatry, New York, NY, USA University of Wisconsin-Madison, Department of Surgery, Madison, WI, USA Chinese Academy of Sciences, Shanghai Institute of Nutrition and Health, CAS Key Laboratory of Tissue Microenvironment & Tumor, Laboratory of Molecular Cardiology, Shanghai, China Capital Medical University, School of Basic Medical Sceinces, Department of Neurobiology, Beijing, China University of Kentucky, Department of Cancer Biology & Toxicology, Lexington, KY, USA University of Alabama at Birmingham, Department of Medicine, Division of Cardiovascular Disease, Birmingham, AL, USA University of Iowa Carver College of Medicine, Fraternal Order of Eagles Diabetes Research Center, Department of Anatomy and Cell Biology, Iowa City, IA, USA The Fourth Military Medical University, Xijing Hospital, Department of Orthopaedics, Xi'an, China Shandong Cancer Hospital and Institute, Cancer Research Center, Jinan, Shandong Province, China Taipei Medical University, College of Medical Science and Technology, Graduate Institute of Cancer Biology and Drug Discovery, Taipei, Taiwan The Fourth Military Medical University, Tangdu Hospital, Department of Experimental Surgery, Xi'an, Shaanxi, China Chung Shan Medical University, Institute of Medicine, Taichung, Taiwan Jiangsu University, School of Medicine, Zhenjiang, Jiangsu, China Yale University School of Medicine, Department of Comparative Medicine and Department of Cellular and Molecular Physiology, New Haven, CT, USA Jinan University, Medical College, Key Laboratory for Regenerative Medicine of the Ministry of Education, Division of Histology and Embryology, Guangzhou, China Hangzhou Normal University, School of Medicine, College of Pharmacy, Hangzhou, Zhejiang, China University of Southeast, School of Medicine, Department of Pharmacology, Nanjing, JiangSu, China University of Melbourne, Bio21 Molecular Science and Biotechnology Institute, Parkville, Victoria, Australia Chinese University of Hong Kong, School of Biomedical Sciences, Hong Kong, China Fourth Medical Center of the Chinese PLA General Hospital, Trauma Research Center, Beijing, China Duke-NUS Medical School, Cardiovascular and Metabolic Disorders Program, Singapore, Singapore Zhejiang University School of Medicine, Department of Biochemistry, and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Hangzhou, China Shandong Agricultural University, College of Plant Protection, Shandong, China Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, China Soochow University, College of Pharmaceutical Sciences, Department of Pharmacology, Suzhou, Jiangsu, China The University of British Columbia, Department of Biochemistry and Molecular Biology, Vancouver, BC, Canada Dong-A University College of Medicine, Department of Anatomy and Cell Biology, Busan, Korea The Jikei University School of Medicine, Department of Biochemistry, Minato-ku, Tokyo, Japan ETH Zürich, Institute of Biochemistry, Zürich, Switzerland Tabriz University of Medical Sciences, Molecular Medicine Research Center, Tabriz, Iran Hwa Chong Institution, Singapore, Singapore Tianjin University of Traditional Chinese Medicine, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin, China Temple University, Center for Metabolic Disease Research and Department of Physiology, Philadelphia, PA, USA The Chinese University of Hong Kong, State Key Laboratory of Digestive Disease, Department of Medicine and Therapeutics, Hong Kong, China Tsinghua University, School of Life Sciences, Tsinghua University-Peking University Joint Center for Life Sciences, State Key Laboratory of Membrane Biology, Beijing, China Hepatobiliary Section, Department of Internal Medicine, Kaohsiung Medical University Hospital, and Hepatitis Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan University of Toronto, Centre for Addiction and Mental Health, Toronto, Ontario, Canada Air Force Medical University, Xijing Hospital, Department of Plastic and Reconstructive Surgery, Xi'an, China Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 201203 Shanghai, China; Department of Cell Biology, Harvard Medical School, Boston, MA, USA Central South University, The Second Xiang-Ya Hospital, National Clinical Research Center for Metabolic Diseases, Department of Metabolism and Endocrinology, Changsha, Hunan, China Kaohsiung Medical University, Graduate Institute of Medicine, Kaohsiung, Taiwan First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China Beijing Institute of Basic Medical Sciences, Beijing, China City University of Hong Kong, Department of Biomedical Sciences, Hong Kong, China Icahn School of Medicine at Mount Sinai, Departments of Neurology and Neuroscience, New York, NY, USA Graduate School of Dong-A University, College of Medicine, Department of Translational Biomedical Sciences, Busan, Korea Centre for Genomic Regulation (CRG), Department of Cell and Developmental Biology, Barcelona, España Laboratory of Pain and Signaling, Butantan Institute, Sao Paulo, SP, Brazil; Stanford University, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford, CA, USA University of Brescia, Department of Molecular and Translational Medicine, Brescia, Italy University of Texas Southwestern Medical Center, Department of Surgery, Dallas, TX, USA Cancer Research UK Beatson Institute, Glasgow, UK; University of Glasgow, Institute of Cancer Sciences, Glasgow, UK University of California, Davis, Department of Pathology and Laboratory Medicine, Shriners Hospitals for Children, Institute for Pediatric Regenerative Medicine, Sacramento, CA, USA Tabriz University of Medical Sciences, Faculty of Advanced Medical Sciences, Department of Medical Nanotechnology, Tabriz, Iran University Monastir, Faculty of Medicine, LR12ES05, Lab-NAFS ‘Nutrition - Functional Food & Vascular Health’, Monastir, Tunisia University of Virginia, Department of Neuroscience, Charlottesville, VA, USA Boston University, Department of Biomedical Engineering, Boston, MA, USA University of Arizona, Department of Pharmacology and Toxicology, Tucson, AZ, USA Peking University First Hospital, Renal Division, Xi Cheng District, Beijing, China Chinese Academy of Sciences, Institute of Biophysics, National Laboratory of Biomacromolecules, Beijing, China Zhejiang University School of Medicine, Department of Pathology, Hangzhou, China University of Science & Technology of China, School of Life Sciences, Hefei, Anhui, China Rutgers Robert Wood Johnson Medical School, Department of Neuroscience and Cell Biology, Piscataway, NJ, USA Thomas Jefferson University/Vickie & Jack Farber Institute for Neuroscience, Hospital for Neuroscience, Philadelphia, PA, USA Soochow University, Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, College of Pharmaceutical Science, Suzhou, Jiangsu, China People's Hospital of Hangzhou Medical College, Zhejiang Provincial People's Hospital, Department of Oncology, Hangzhou, China; Zhejiang Provincial People's Hospital, Clinical Research Institute, Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province, Hangzhou, China University of Alabama at Birmingham, Department of Pathology, Birmingham, AL, USA School of Radiation Medicine and Protection and State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, China The Chinese University of Hong Kong, Department of Medicine and Therapeutics and Department of Anaesthesia and Intensive Care, Hong Kong, China Huazhong Agricultural University, School of Veterinary Medicine/ Biomedical Center, Hongshan, Wuhan, China Henan University of Technology, College of Bioengineering, Zhengzhou, China University of Utah, Huntsman Cancer Institute and Department of Oncological Sciences, Salt Lake City, UT, USA The University of Texas Health Science Center at Houston (UTHealth), McGovern Medical School, The Brown Foundation Institute of Molecular Medicine, Department of Neurobiology and Anatomy, Programs in Human and Molecular Genetics and Neuroscience of the MD Anderson UTHealth GSBS, Houston, TX, USA Wake Forest Baptist Comprehensive Cancer Center, Department of Cancer Biology, Winston-Salem, NC, USA Hungarian Academy of Sciences, Budapest, Hungary; Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Budapest, Hungary The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Department of Orthopaedics, Wenzhou, Zhejiang Province, China College of Respiratory and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China University of Newcastle, School of Biomedical Sciences and Pharmacy, NSW, Australia University of Houston, College of Pharmacy, Department of Pharmacological & Pharmaceutical Sciences, Houston, TX, USA University of Maryland, Molecular Virology Laboratory, VA-MD College of Veterinary Medicine, College Park, MD, USA East China Normal University, Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education, Shanghai, China Nanjing Agricultural University, College of Plant Protection, Department of Plant Pathology, Nanjing, China Department of Physiology, Department of Obstetrics/Gynecology, Wayne State University, Detroit, MI, USA Rutgers University, Department of Surgery, New Brunswick, NJ, USA Nanjing University of Chinese Medicine, Nanjing, China Central China Normal University, College of Life Sciences, Wuhan, Hubei Province, China The Fourth Military Medical University, National Key Discipline of Cell Biology, Department of Physiology and Pathophysiology, Xi'an, Shaanxi, China The Fourth Military Medical University, Tangdu Hospital, Department of Neurosurgery, Xi'an, Shaanxi, China Beijing Academy of Agriculture and Forestry Sciences, Institute of Plant and Environment Protection, Beijing, China Shandong University, School of Life Sciences, Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, Qingdao, China Peking University Health Sciences Center, Department of Biochemistry and Molecular Biology, Beijing, China Zhejiang University, the First Affiliated Hospital, Hangzhou, Zhejiang, China Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China University of Sydney, Westmead Institute for Medical Research, Centre for Transplant and Renal Research, Sydney NSW, Australia Shenzhen University, Health Science Center, School of Pharmaceutical Sciences, Shenzhen, Guangdong, China Wuhan University, Department of Cell Biology, College of Life Sciences, Wuhan, Hubei, China University of Calgary, Cumming School of Medicine, Libin Cardiovascular Institute of Alberta, Departments of Biochemistry & Molecular Biology and Physiology & Pharmacology, Calgary, Alberta, Canada Children’s Hospital Medical Center, Division of Experimental Hematology and Cancer Biology, Cincinnati, OH, USA China Pharmaceutical University, State Key Laboratory of Natural Medicines, Nanjing, Jiangsu, China Karolinska Institutet Division of Toxicology, Institute of Environmental Medicine, Stockholm, Sweden; Lomonosov Moscow State University, Faculty of Basic Medicine, Moscow, Russia Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China Southwest Medical University, Department of Medical Cellular Biology, Luzhou, Sichuan, China Massachusetts General Hospital, Department of Medicine, Diabetes Unit and Center for Genomic Medicine, Boston, MA, USA; Harvard Medical School, Department of Medicine, Boston, MA, USA Chinese People's Liberation Army General Hospital, Department of Cardiology, Beijing, China Third Military Medical University, College of Pharmacy, Department of Pharmacology, Chongqing, China Huazhong Agricultural University, College of Veterinary Medicine, State Key Laboratory of Agricultural Microbiology, Wuhan, China Zhejiang University, Department of Horticulture, Hangzhou, China Guangxi Medical University, School of Preclinical Medicine, Department of Physiology, Nanning,China Zhejiang University, MOA Key Laboratory of Animal Virology, Hangzhou, Zhejiang, China The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Department of Orthopaedics, Wenzhou, Zhejiang, China Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, CAS Key Laboratory of Regenerative Biology, Guangzhou, China Queensland University of Technology, Institute of Health and Biomedical Innovation, Brisbane, QLD, Australia Texas A&M University, Institute of Biosciences and Technology, Houston, TX, USA Soochow University, Laboratory Animal Center, Suzhou, Jiangsu Province, China Zhejiang University School of Medicine, Department of Environmental Medicine, Hangzhou, Zhejiang Province, China University at Buffalo, The State University of New York, Department of Physiology and Biophysics, Buffalo, NY, USA Zhengzhou University, Third Affiliated Hospital and Institute of Neuroscience, Henan Key Laboratory of Child Brain Injury, Zhengzhou, China; Gothenburg University, Institute of Neuroscience and Physiology, Gothenburg, Sweden Nanjing Medical University, Department of Physiology, Nanjing, Jiangsu, China University of Kentucky, College of Medicine, Department of Molecular and Cellular Biochemistry, Lexington, KY, USA Shanghai Jiao Tong University, Bio-X Institutes, Shanghai, China The Ohio State University, Department of Surgery, Columbus, OH, USA Shenzhen University Medical School, Department of Biochemistry and Molecular Biology, Shenzhen, China State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China University California, San Diego, Division of Biological Sciences, Section of Molecular Biology, CA, USA University Medical Center of Johannes Gutenberg-University, Institute for Virology, Mainz, Germany University of Padova, Biology Department, Padova, Italy Rutgers University, Department of Chemical Biology, Ernest Mario School of Pharmacy, Piscataway, NJ, USA Moscow State University, A.N.Belozersky Institute of Physico-Chemical Biology, Department of Functional Biochemistry of Biopolymers, Moscow, Russia University of Michigan, Departments of Surgery and Pathology, Ann Arbor, MI, USA Institute of Life Sciences, Chongqing Medical University, Chongqing, PR China The University of Queensland, Queensland Brain Institute, Clem Jones Centre for Ageing Dementia Research, Brisbane, Australia University of Innsbruck, Division of Cell Metabolism and Differentiation Research, Research Institute for Biomedical Aging Research, Innsbruck, Austria Indiana University School of Medicine, Department of Biochemistry and Molecular Biology, Indianapolis, IN, USA Swedish University of Agricultural Sciences, Department of Forest Mycology and Plant Pathology, Uppsala, Sweden Southern Medical University, Shenzhen Hospital, Department of Pathology, Bao'an District, Shenzhen, Guangdong, China Lovelace Respiratory Research Institute, Molecular Biology and Lung Cancer Program, Albuquerque, NM, USA Tokyo Medical and Dental University (TMDU), Medical Hospital, Department of Gastroenterology and Hepatology, Bunkyo-ku, Tokyo, Japan. Huazhong University of Science and Technology, School of Basic Medicine, Wuhan, HuBei, China Maastricht University Medical Center, School for Cardiovascular disease (CARIM), Department of Pathology, Maastricht, The Netherlands; University of Edinburgh, Centre for Cardiovascular Science, Edinburgh, UK Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA Hong Kong Baptist University, School of Chinese Medicine, Hong Kong, China Hong Kong Baptist University, School of Chinese Medicine, Hong Kong, lxChina C2 LIFE SCIENCES INSTITUTE AND DEPARTMENT OF MOLECULAR, USA DEPARTMENT OF PHARMACOLOGY AND TOXICOLOGY, ITALY JOHANNES GUTENBERG UNIVERSITY, GERMANY MEDICAL UNIV GRAZ, AUSTRIA PASTEUR INSTITUTE OF IRAN, IRAN DEPARTMENT OF MOLECULAR SIGNAL PROCESSING, GERMANY UNIV HEBREW JERUSALEM, ISRAEL DANISH CANCER SOCIETY RESEARCH CENTER, DENMARK UNIV COPENHAGEN, DENMARK UNIV TROMSØ - THE ARCTIC UNIV NORWAY, NORWAY HOSPITAL UNIVERSITARIO DE CANARIAS, SPAIN UNIV CALIFORNIA, USA UNIV TORONTO, CANADA MEDICAL UNIV INNSBRUCK, AUSTRIA UNIV CALABRIA, ITALY NATIONAL INSTITUTES OF HEALTH, USA BEN-GURION UNIV THE NEGEV, ISRAEL UNIV ALABAMA AT BIRMINGHAM, USA INFLAMMATION RESEARCH CENTER, USA UNIV PALERMO, ITALY CELL DEATH RESEARCH & THERAPY (CDRT) LAB, BELGIUM INDIAN INSTITUTE OF TECHNOLOGY, INDIA UNIV DUNDEE, UK UNIV TEXAS MEDICAL BRANCH, USA COLBY COLLEGE, USA UNIV MARYLAND SCHOOL OF MEDICINE, USA UNIVERSIDAD MAYOR, CHILE LUND UNIVERSITY, SWEDEN NIHON UNIVERSITY, JAPAN KOC UNIV SCHOOL OF MEDICINE, TURKEY UNIV CRETE, GREECE UNIV CRETE, GREECE THE INSTITUTE OF CANCER RESEARCH, UK PHARMACEUTICAL SCIENCES DEPARTMENT, UNITED ARAB EMIRATES UNIV SYDNEY, AUSTRALIA INSIGHT INSTITUTE OF NEUROSURGERY & NEUROSCIENCE, USA MCGILL UNIVERSITY, CANADA TECHNICAL UNIV DRESDEN, GERMANY UNIVERSIDAD DE SEVILLA, SPAIN SAPIENZA UNIV ROME, ITALY THE WILMER EYE INSTITUTE, USA UNIV RAJSHAHI, BANGLADESH DEPARTMENT OF BIOLOGICAL SCIENCES AND BIOTECHNOLOGY, PALESTINE DEPARTMENT OF HUMAN ANATOMY AND CELL SCIENCE, CANADA UNIV BARCELONA, SPAIN METABOLISM AND CANCER LABORATORY, SPAIN THE FRANCIS CRICK INSTITUTE, UK CLEVELAND CLINIC, USA UNIV PAIS VASCO EHU, SPAIN INSTITUTO DE INVESTIGACIONES EN INGENIERIA GENETICA Y BIOLOGIA MOLECULAR “DR. HECTOR N. TORRES”, ARGENTINA LABORATORY OF HOST-PATHOGEN DYNAMICS, USA THE WISTAR INSTITUTE, USA BUENOS AIRES UNIVERSITY, ARGENTINA UNIVERSIDADE DO PORTO, PORTUGAL UNIV NICE, FRANCE ISLAMIC UNIV GAZA, PALESTINE UNIV PAVIA, ITALY UNIV CAMERINO, ITALY UNIV PORTO, PORTUGAL TELETHON INSTITUTE OF GENETICS AND MEDICINE (TIGEM), ITALY OHIO STATE UNIVERSITY, USA Save as Ravi Manjithaya UNIV CALIFORNIA, USA AARHUS UNIVERSITY, DENMARK DEPARTMENTS OF PHARMACOLOGY AND TOXICOLOGY, USA FEDERAL UNIV SAO PAULO, BRAZIL UNIVERSIDADE NOVE DE JULHO (UNINOVE), BRAZIL CEDARS-SINAI MEDICAL CENTER, USA UNIV BOLOGNA, ITALY CITY OF HOPE COMPREHENSIVE CANCER CENTER, USA UNIV TENNESSEE, USA NORTHEAST OHIO MEDICAL UNIVERSITY, USA INOVA4HEALTH CHRONIC DISEASES RESEARCH CENTER (CEDOC), PORTUGAL MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING AND CECAD, GERMANY SCHOOL OF BIOCHEMISTRY, UK UNIV HELSINKI, FINLAND INSERM, FRANCE UNIV VALENCIA, SPAIN NATIONAL INSTITUTE OF NEUROSCIENCE, JAPAN OSAKA UNIVERSITY, JAPAN TOKYO UNIV PHARMACY AND LIFE SCIENCES, JAPAN UNIVERSIDADE FEDERAL DE VICOSA, BRAZIL THE JIKEI UNIV SCHOOL OF MEDICINE, JAPAN NEWCASTLE UNIVERSITY, UK INSTITUTO CAJAL, SPAIN UNIV SEVILLE, SPAIN ALBERT EINSTEIN COLLEGE OF MEDICINE, USA HOWARD UNIV COLLEGE OF MEDICINE, USA TOHOKU UNIVERSITY, JAPAN UNIV MICHIGAN, USA IMPERIAL COLLEGE LONDON, UK TOULOUSE UNIVERSITY, FRANCE IOWA STATE UNIVERSITY, USA UNIVERSIDAD NACIONAL DE CORDOBA, ARGENTINA YORK COLLEGE/THE CITY UNIV NEW YORK, USA TRANSLATIONAL GENOMICS GROUP, SPAIN UNIV PALERMO, ITALY ALBERT EINSTEIN COLLEGE OF MEDICINE, USA FACULTY OF ENGINEERING AND NATURAL SCIENCES, TURKEY MEIR MEDICAL CENTER, ISRAEL THE INSTITUTE OF GENETICS AND ANIMAL BIOTECHNOLOGY, AUSTRIA UNIV PITTSBURGH MEDICAL CENTER, USA UNIV NICE, FRANCE IMPERIAL COLLEGE LONDON, UK DEPARTMENTS OF PHARMACOLOGY AND MICROBIOLOGY, USA UNIV TURIN, ITALY UNIV MILAN, ITALY UNIVERSIDAD DE SANTIAGO DE CHILE, CHILE FONDAZIONE ISTITUTO DI RICERCA PEDIATRICA CITTA DELLA SPERANZA, ITALY CNC - CENTER FOR NEUROSCIENCE AND CELL BIOLOGY, PORTUGAL THE HEBREW UNIV JERUSALEM, ISRAEL TULANE HEALTH SCIENCES CENTER, USA MELBOURNE DEMENTIA RESEARCH CENTRE, AUSTRALIA UNIV ARKANSAS FOR MEDICAL SCIENCES, USA UNIV MALTA, MALTA KOGAKUIN UNIVERSITY, JAPAN ALBERT EINSTEIN COLLEGE OF MEDICINE, USA EASTERN MICHIGAN UNIVERSITY, USA HANYANG UNIVERSITY, KOREA YONSEI UNIV COLLEGE OF MEDICINE, KOREA UNIV MASSACHUSETTS MEDICAL SCHOOL, USA KONKUK UNIVERSITY, KOREA AJOU UNIVERSITY, KOREA SEOUL NATIONAL UNIVERSITY, SOUTH KOREA UNIV CALABRIA, ITALY ADAM MICKIEWICZ UNIVERSITY/FACULTY OF BIOLOGY, POLAND IOWA STATE UNIVERSITY, USA KUNMING UNIV SCIENCE AND TECHNOLOGY, CHINA NATIONAL JEWISH HEALTH, USA UNIV TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO, USA JADAVPUR UNIVERSITY, INDIA KAROLINSKA INSTITUTE, SWEDEN UNIV GENOA, ITALY UNIV SIENA, ITALY UNIV URBINO CARLO BO, ITALY TELETHON INSTITUTE OF GENETICS AND MEDICINE (TIGEM), USA UNIV NAPLES FEDERICO II, ITALY IRTA, SPAIN MAX PLANCK INSTITUTE OF MOLECULAR PLANT PHYSIOLOGY, GERMANY UCL QUEEN SQUARE INSTITUTE OF NEUROLOGY, UK MIDDLE EAST TECHNICAL UNIVERSITY, TURKEY UNIV MIAMI, USA UNIV MIAMI, USA UNIV NICE, FRANCE SCHOOL OF AGRICULTURE AND BIOLOGY, CHINA UNIVERSIDADE DE SAO PAULO. DEPARTMENT OF BIOCHEMISTRY, BRAZIL UNIV BOLOGNA, ITALY UNIV ROME TOR VERGATA, ITALY EDINBURGH NAPIER UNIVERSITY, UK UNIV MICHIGAN, USA PULMONOLOGY DEPARTMENT, SPAIN UNIV LIMERICK, IRELAND DANISH CANCER SOCIETY RESEARCH CENTER, DENMARK RICE UNIVERSITY, USA COLUMBIA UNIVERSITY, USA JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH, INDIA ICAR-INDIAN VETERINARY RESEARCH INSTITUTE, INDIA THE UNIV TEXAS M.D. ANDERSON CANCER CENTER, USA UNIV NORTH TEXAS HEALTH SCIENCE CENTER, USA UNIV LOUVAIN, BELGIUM TRINITY COLLEGE DUBLIN, IRELAND UNIV PARIS-SACLAY, FRANCE UNIV SOUTH CAROLINA UPSTATE, USA INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), FRANCE FRANCIS CRICK INSTITUTE, UK UNIV PARIS-SACLAY, FRANCE UNIV PAU ET DES PAYS DE L’ADOUR, FRANCE UNIV SAO PAULO, BRAZIL EMORY UNIV SCHOOL OF MEDICINE, USA UNIV PENNSYLVANIA, USA MATER RESEARCH INSTITUTE, BRISBANE AUSTRALIA LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN, GERMANY HANNOVER MEDICAL SCHOOL, GERMANY UNIV ROME “TOR VERGATA”, ITALY TUFTS UNIVERSITY, USA UNIVERSIDAD CARDENAL HERRERA-CEU, SPAIN BAR-ILAN UNIVERSITY, ISRAEL UNIV MEDICAL CENTER OF THE JOHANNES GUTENBERG UNIVERSITY, GERMANY BOSTON UNIVERSITY, USA SORBONNE UNIVERSITE, FRANCE ITALIAN LIVER FOUNDATION, ITALY UNIV ROME “SAPIENZA”, ITALY CENTRO NACIONAL DE BIOTECNOLOGIA-CNB-CSIC, SPAIN UNIVERSIDAD AUTONOMA DE MADRID, SPAIN UNIV SAO PAULO, BRAZIL UNIVERSIDAD MAYOR, CHILE UNIV OKLAHOMA HEALTH SCIENCES CENTER/STEPHENSON CANCER CENTER, USA UMR 7242 “BIOTECHNOLOGY AND CELLULAR SIGNALING”, FRANCE WASHINGTON UNIV IN SAINT LOUIS, USA UNIVERSIDAD FRANCISCO DE VITORIA, SPAIN HOPWOOD CENTRE FOR NEUROBIOLOGY, AUSTRALIA UNIV COPENHAGEN, DENMARK UNIV LAUSANNE HOSPITAL AND LAUSANNE UNIVERSITY, SWITZERLAND UNIV LONDON, UK UNIV COLOGNE AND UNIV HOSPITAL COLOGNE, GERMANY UNIV MASSACHUSETTS MEDICAL SCHOOL, USA MAGNA GRAECIA UNIVERSITY, ITALY UNIV PARIS 05, FRANCE CNRS, FRANCE UNIV DU QUEBEC A TROIS-RIVIERES, CANADA UNIV MICHIGAN, USA UNIV MONTPELLIER, FRANCE BRISTOL MEDICAL SCHOOL, UK GHENT UNIVERSITY, BELGIUM UNIV OXFORD, UK UNIV NEW MEXICO, USA COMENIUS UNIVERSITY, SLOVAKIA UNIV OKLAHOMA HEALTH SCIENCES CENTER, USA VANDERBILT UNIV MEDICAL CENTER, USA DEPARTMENT OF BIOPHYSICS, INDIA LOUISIANA STATE UNIV HEALTH SCIENCES CENTER-SHREVEPORT, USA NATIONAL INSTITUTE OF TECHNOLOGY ROURKELA, INDIA MICHIGAN TECHNOLOGICAL UNIVERSITY, USA DALIAN MEDICAL UNIVERSITY, CHINA GARVAN INSTITUTE OF MEDICAL RESEARCH, AUSTRALIA EOTVOS LORAND UNIV (ELTE), HUNGARY FEDERAL UNIV SAO PAULO, BRAZIL UNIV HOSPITAL OF NORTH NORWAY, NORWAY NORWEGIAN UNIV SCIENCE AND TECHNOLOGY, NORWAY UNIV YORK, UK UNIV VALENCIA, SPAIN UNIV LODZ, POLAND LINKOPING UNIVERSITY, SWEDEN KAROLINSKA INSTITUTET, SWEDEN INDIANA UNIV SCHOOL OF MEDICINE, USA ST. JUDE CHILDREN'S RESEARCH HOSPITAL, USA UNIV ZAGREB, CROATIA UNIV PENNSYLVANIA, USA BURNET INSTITUTE, AUSTRALIA UNIV COLLEGE CORK, IRELAND INMG, FRANCE UNIV PADOVA, ITALY INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, FRANCE NATIONAL INSTITUTES OF HEALTH, USA WEST VIRGINIA UNIVERSITY, USA THE OPEN UNIVERSITY, UK UNIV ROME TOR VERGATA, ITALY IRCCS BAMBINO GESU CHILDREN’S HOSPITAL, ITALY ALBERT LUDWIGS UNIV FREIBURG, GERMANY UNIV CHILDREN’S HOSPITAL ZURICH, SWITZERLAND UNIV TEXAS M.D. ANDERSON CANCER CENTER, USA CASE WESTERN RESERVE UNIV SCHOOL OF MEDICINE, USA WASHINGTON STATE UNIVERSITY, USA UNIV SANTIAGO DE COMPOSTELA, SPAIN BAYLOR COLLEGE OF MEDICINE, USA UNIV PARIS, FRANCE UNIV ALABAMA AT BIRMINGHAM, USA ALBERT EINSTEIN COLLEGE OF MEDICINE, USA MEDICAL UNIV GRAZ, AUSTRIA UNIV PARIS 13, FRANCE CENTRO DE INVESTIGACIONES BIOLOGICAS MARGARITA SALAS, SPAIN SWEDISH UNIV AGRICULTURAL SCIENCES AND LINNEAN CENTER FOR PLANT BIOLOGY, SWEDEN STANFORD UNIVERSITY, USA IMPERIAL COLLEGE LONDON, UK THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION, USA GOETHE UNIVERSITY, GERMANY DANUBE PRIVATE UNIVERSITY, AUSTRIA GEORG-AUGUST-UNIVERSITAT GOTTINGEN, GERMANY UNIVERSIDAD DE CHILE, CHILE UNIV PARIS, FRANCE UNIV COTE D'AZUR (UCA), FRANCE CENTRE DES SCIENCES DU GOUT ET DE L'ALIMENTATION, FRANCE NATIONAL AUTONOMOUS UNIV MEXICO, MEXICO UNIV CALIFORNIA SAN FRANCISCO, USA UNIV COPENHAGEN, DENMARK UNIV PITTSBURGH, USA WASHINGTON UNIV SCHOOL OF MEDICINE, USA DEPARTMENT OF HUMAN GENETICS, USA DAVID GEFFEN SCHOOL OF MEDICINE AT UCLA, USA UNIV COLORADO, USA UNIV MINNESOTA, USA UNIV SAO PAULO, BRAZIL HOSPITAL FOR SICK CHILDREN, CANADA UNIV INSUBRIA, ITALY MONASH UNIVERSITY, AUSTRALIA UNIV SALENTO, ITALY INSTITUT PASTEUR, FRANCE UNIV PITTSBURGH, USA UNIV DUISBURG-ESSEN, GERMANY THOMAS JEFFERSON UNIVERSITY, USA DEPARTMENT OF PHARMACOLOGY AND EXPERIMENTAL NEUROSCIENCE, USA UNIV ARIZONA, USA UNIV IOWA, USA MONTANA BIOAG. INC. MISSOULA, USA UNIVERSIDAD DE CHILE, CHILE KU LEUVEN, BELGIUM UNIV MEDICINE AND PHARMACY OF CRAIOVA, ROMANIA KING'S COLLEGE LONDON, UK UNIV CORDOBA, SPAIN THE ROCKEFELLER UNIVERSITY, USA STOCKHOLM UNIVERSITY, SWEDEN UNIV VERONA, ITALY DEPARTMENTO DE BIOLOGIA CELULAR E HISTOLOGIA, SPAIN UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO, MEXICO NEW YORK UNIV SCHOOL OF MEDICINE, USA WENZHOU MEDICAL UNIVERSITY, CHINA UNIV LOUISVILLE, USA RUTGERS UNIVERSITY, USA UNIV BARCELONA, SPAIN UNIV LAS PALMAS DE GRAN CANARIA, NORWAY UNIV ALABAMA, USA UNIV GEORGIA, USA FONDAZIONE POLICLINICO UNIVERSITARIO “AGOSTINO GEMELLI” IRCCS, ITALY UNIV ZARAGOZA, SPAIN UNIV SAO PAULO, BRAZIL CNRS, FRANCE UNIV BORDEAUX, FRANCE UNIV LONDON, UK LOYOLA UNIVERSITY, USA UNIV OTTAWA, CANADA UNIV ROME “TOR VERGATA”, ITALY UNIVERSITA DI SASSARI, ITALY UNIV NICE, FRANCE UNIVERSIDAD SAN SEBASTIAN, CHILE UNIV TORONTO, CANADA IRBLLEIDA-UNIV LLEIDA, SPAIN XIAMEN UNIV SCHOOL OF MEDICINE, CHINA UNIV CAMPANIA “L. VANVITELLI”, ITALY INSTITUTO DE INVESTIGACION BIOMEDICA DE A CORUNA (INIBIC), SPAIN UNIV WISCONSIN, USA UNIV GENEVA, SWITZERLAND UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO, MÉXICO UNIV COIMBRA, PORTUGAL UNIV ARIZONA CANCER CENTER, USA UNIV NICE, FRANCE TREV AND JOYCE DEELEY RESEARCH CENTRE, CANADA UNIV GRAZ, AUSTRIA FEDERAL UNIV RIO DE JANEIRO, BRAZIL POLYTECHNIC UNIV MARCHE, ITALY UNIV MODENA AND REGGIO EMILIA, ITALY CENTRE DE RECHERCHE EN CANCEROLOGIE DE MARSEILLE (CRCM), FRANCE FUNCTIONAL GENOMICS OF CARDIOMYOPATHIES, GERMANY UNIV ALABAMA AT BIRMINGHAM, USA UNIVERSIDADE DE LISBOA, PORTUGAL UNIV AIX MARSEILLE, FRANCE UNIVERSITAT AUTONOMA DE BARCELONA, SPAIN INSTITUTE FOR ADVANCED CHEMISTRY OF CATALONIA (IQAC-CSIC), SPAIN UNIV NEW MEXICO HEALTH SCIENCES CENTER, USA UNIVERSIDAD DE VALPARAISO, CHILE COMPLUTENSE UNIVERSITY, SPAIN UNIV PARIS, FRANCE DIVISION OF MEDICAL GENETICS, ITALY UNIVERSIDAD DE CONCEPCION, CHILE UNIVERSIDADE NOVA DE LISBOA, PORTUGAL UNIVERSIDAD DE LA LAGUNA, SPAIN UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (UNAM), MÉXICO UNIV CALIF SAN DIEGO, USA UNIV COIMBRA, PORTUGAL UNIV PISA, ITALY UNIV INNSBRUCK, AUSTRIA BIOMEDICAL RESEARCH INSTITUTE OF MURCIA, SPAIN RESEARCH CENTER BORSTEL, GERMANY DANISH CANCER SOCIETY RESEARCH CENTER, ITALY MEDICAL UNIV BIALYSTOK, POLAND OSPEDALE SAN RAFFAELE AND VITA-SALUTE SAN RAFFAELE UNIVERSITY, ITALY HOSPITAL UNIVERSITARI DE TARRAGONA JOAN XXIII, SPAIN UNIV MINHO, PORTUGAL UNIVERSIDADE FEDERAL DE SAO PAULO, BRAZIL UNIV TUSCIA, ITALY EGE UNIVERSITY, TURKEY SCHOOL OF PHARMACY, SOUTH KOREA KAROLINSKA INSTITUTET, SWEDEN KAOHSIUNG MEDICAL UNIVERSITY, TAIWAN UNIV CALCUTTA, INDIA SAHA INSTITUTE OF NUCLEAR PHYSICS, INDIA EHIME UNIVERSITY, JAPAN JUSTUS-LIEBIG-UNIV GIESSEN, GERMANY THE UNIV HONG KONG, CHINA QUEEN'S UNIVERSITY, CANADA THE CHINESE UNIV HONG KONG, CHINA THE CHINESE UNIV HONG KONG, CHINA THE CHINESE UNIV HONG KONG, CHINA TULANE UNIV SCHOOL OF MEDICINE, USA NATIONAL CHENG KUNG UNIVERSITY, TAIWAN UNIV CALIFORNIA, USA NATIONAL UNIV SINGAPORE, SINGAPORE SOUTHEAST UNIVERSITY, CHINA UNIV EAST ANGLIA, UK INSTITUT DE GENETIQUE ET DE BIOLOGIE MOLECULAIRE ET CELLULAIRE (IGBMC), FRANCE NCR BIOTECH SCIENCE CLUSTER, INDIA BANARAS HINDU UNIVERSITY, INDIA UNIV WASHINGTON, USA INSTITUTE OF LIFE SCIENCES, INDIA UCL INSTITUTE OF OPHTHALMOLOGY, UK NATIONAL CHENG KUNG UNIVERSITY, TAIWAN ACADEMIA SINICA, TAIWAN UNIV SOUTHERN CALIFORNIA, USA UNIV MINNESOTA MEDICAL SCHOOL, USA QINGDAO UNIVERSITY, CHINA ARMY MEDICAL UNIV (THIRD MILITARY MEDICAL UNIVERSITY), CHINA THIRD MILITARY MEDICAL UNIVERSITY, CHINA CHANGHUA CHRISTIAN HOSPITAL, TAIWAN WUHAN SPORTS UNIVERSITY, CHINA COLLEGE OF LIFE SCIENCES, CHINA WUHAN UNIVERSITY, CHINA DUKE UNIVERSITY, USA CHINESE ACADEMY OF SCIENCES, CHINA UNIV SYDNEY, AUSTRALIA TEMPLE UNIVERSITY, USA CHINESE ACADEMY OF MEDICAL SCIENCES AND PEKING UNION MEDICAL COLLEGE, CHINA SHANGHAI INSTITUTE OF NUTRITION AND HEALTH, CHINA TSINGHUA UNIVERSITY, CHINA PEKING UNIV SCHOOL OF BASIC MEDICAL SCIENCE, CHINA RESEARCH INSTITUTE IN ONCOLOGY AND HEMATOLOGY, CANADA MACKAY MEMORIAL HOSPITAL, TAIWAN SUN YAT-SEN UNIVERSITY, CHINA WUHAN UNIVERSITY, CHINA 2ND AFFILIATED HOSPITAL OF ZHEJIANG UNIV SCHOOL OF MEDICINE, CHINA UNIV TEXAS SOUTHWESTERN MEDICAL CENTER, USA PURDUE UNIVERSITY, USA WUHAN UNIVERSITY, CHINA CAPITAL MEDICAL UNIVERSITY, CHINA NORTHWESTERN UNIV FEINBERG SCHOOL OF MEDICINE, USA ALBERT EINSTEIN COLLEGE OF MEDICINE, USA THE UNIV TEXAS HEALTH SCIENCE CENTER AT HOUSTON, USA NATIONAL INSTITUTES OF HEALTH, USA EAST CHINA NORMAL UNIVERSITY, CHINA UNIV FLORIDA, USA ZHEJIANG UNIVERSITY, CHINA NATIONAL CANCER CENTER KOREA, KOREA NATIONAL UNIV SINGAPORE, SINGAPORE NATIONAL UNIV SINGAPORE, SINGAPORE LOMONOSOV MOSCOW STATE UNIVERSITY, RUSSIA UNIV PENNSYLVANIA, USA NATIONAL CHENG KUNG UNIVERSITY, TAIWAN SUN YAT-SEN UNIVERSITY, CHINA INSERM U1242, FRANCE UNIV NORTH CAROLINA AT CHARLOTTE, USA THE UNIV HONG KONG, CHINA UNIV MILANO-BICOCCA, ITALY ISTITUTO DI FISIOLOGIA CLINICA, ITALY THE NORWEGIAN RADIUM HOSPITAL, NORWAY THE NORWEGIAN RADIUM HOSPITAL, NORWAY IEO, ITALY UNIV CHILE, CHILE TAIPEI VETERANS GENERALS HOSPITAL, TAIWAN NATIONAL INSTITUTES OF HEALTH (NIH), USA INSTITUTE OF TRANSLATIONAL PHARMACOLOGY, ITALY KYUNGPOOK NATIONAL UNIVERSITY, KOREA WONKWANG UNIV SCHOOL OF MEDICINE, KOREA WEILL CORNELL MEDICINE, USA WEILL CORNELL MEDICINE, USA CSIR-INDIAN INSTITUTE OF CHEMICAL BIOLOGY, INDIA BC CANCER RESEARCH CENTRE, CANADA UNIV PITTSBURGH SCHOOL OF MEDICINE, USA NATIONAL UNIV SINGAPORE, SINGAPORE KONKUK UNIV SCHOOL OF MEDICINE, KOREA MAX-PLANCK-INSTITUT FUR MOLEKULARE PFLANZENPHYSIOLOGIE, GERMANY UNIV ULSAN COLLEGE OF MEDICINE, KOREA THE CATHOLIC UNIV KOREA, KOR INSTITUTE OF CANCER RESEARCH, UK NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY OF POLISH ACADEMY OF SCIENCES, POLAND UNIV CHILE, CHILE UNIV COLOGNE, GERMANY UNIV ROME “LA SAPIENZA”, ITALY UNIV LIVERPOOL, UK MOLECULAR PHYSIOLOGY AND CELL SIGNALING, UK UNIVERSITA DI MILANO, ITALY ISTITUTO SUPERIORE DI SANITA, ITALY INSTITUT NECKER-ENFANTS MALADES (INEM), FRANCE THE HEBREW UNIV JERUSALEM, ISRAEL UNIV ROMA TRE, ITALY NATIONAL INSTITUTES OF HEALTH, USA INSTITUT D'INVESTIGACIONS BIOMEDIQUES DE BARCELONA (CSIC, SPAIN UNIV BELGRADE, SERBIA IRTA, SPAIN UNIV SHEFFIELD, UK INSTITUTO DE HISTOLOGIA Y EMBRIOLOGIA (IHEM)-UNIVERSIDAD NACIONAL DE CUYO-CONICET, ARGENTINA YALE UNIV SCHOOL OF MEDICINE, USA CLERMONT-AUVERGNE UNIVERSITY, FRANCE UNIV PAVIA, ITALY FEDERAL UNIV SAO CARLOS, BRAZIL DEPARTMENT OF PATHOLOGY AND EXPERIMENTAL THERAPEUTICS AND INSTITUTE OF BIOMEDICINE OF THE UNIV BARCELONA (IBUB), ITALY NATIONAL INSTITUTES OF HEALTH, USA RUTGERS UNIVERSITY, USA NATIONAL INSTITUTES OF HEALTH, USA UNIV MANITOBA, CANADA JOHNS HOPKINS UNIVERSITY, USA UNIV MAGNA GRAECIA OF CATANZARO, ITALY UMEA UNIVERSITY, SWEDEN ONCORAY NATIONAL CENTER FOR RADIATION RESEARCH IN ONCOLOGY, GERMANY ONCORAY NATIONAL CENTER FOR RADIATION RESEARCH IN ONCOLOGY, GERMANY UNIV GENOA, ITALY UNIV MICHIGAN MEDICAL SCHOOL, USA UNIV ZURICH, SWITZERLAND UNIV OVIEDO, SPAIN UNIV MELBOURNE, AUSTRALIA CSIC-UNIVERSIDAD DE SEVILLA, SPAIN UNIVERSIDAD DE CHILE, CHILE UNIVERSITA DEGLI STUDI DI MILANO, ITALY DEPARTMENT OF ANATOMY, HUNGARY CENTRO DE INVESTIGACION BIOMEDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS (CIBERNED), SPAIN CHINESE ACADEMY OF MEDICAL SCIENCES & PEKING UNION MEDICAL COLLEGE, CHINA SUN YAT-SEN UNIVERSITY, CHINA MEDICAL RESEARCH INSTITUTE, CHINA THE CHINESE UNIV HONG KONG, CHINA UNIV PARIS-SACLAY, FRANCE UNIV MAR DEL PLATA, ARGENTINA MCGILL UNIV HEALTH CENTRE, CANADA EMORY UNIV SCHOOL OF MEDICINE, USA MEDICAL UNIV LUBLIN, POLAND UNIV BOLOGNA, ITALY UNIV CAMPUS BIO-MEDICO, ITALY ISTITUTO DERMOPATICO DELL'IMMACOLATA, ITALY UNIV FLORIDA, USA UNIV “G. D'ANNUNZIO”, ITALY FEDERAL UNIV SERGIPE, BRAZIL UNIV COLOGNE, GERMANY UNIV NEVADA, USA GREGOR MENDEL INSTITUTE, AUSTRIA UNIV NAPLES FEDERICO II, ITALY XI'AN JIAOTONG UNIVERSITY, CHINA THE FIRST HOSPITAL OF JILIN UNIVERSITY, CHINA MODEL ANIMAL RESEARCH CENTER OF NANJING UNIVERSITY, CHINA UNIV SALERNO, ITALY UNIV PADOVA, ITALY RESEARCH CENTER BORSTEL, GERMANY UNIV CLERMONT AUVERGNE, FRANCE CHRISTIAN-ALBRECHTS-UNIV KIEL, GERMANY KAROLINSKA INSTITUTET, SWEDEN UNIV SOUTH FLORIDA, RUSSIA UNIV SOUTH FLORIDA, USA TEXAS TECH UNIV HEALTH SCIENCES CENTER, USA CLEVELAND CLINIC, USA MD ANDERSON CANCER CENTER, USA TULANE UNIV HEALTH SCIENCES CENTER, USA MAX-DELBRUCK-CENTER FOR MOLECULAR MEDICINE, GERMANY INSTITUTE OF LIFE SCIENCES, UK UNIV MASSACHUSETTS MEDICAL SCHOOL, USA STELLENBOSCH UNIVERSITY, SOUTH AFRICA UNIV DUNDEE SCHOOL OF MEDICINE, UK UNIV CALABRIA, ITALY GHENT UNIVERSITY, BELGIUM “SAPIENZA” UNIV ROME, ITALY UNIV VERONA, VERONA; ITALY OSWALDO CRUZ FOUNDATION, BRAZIL UNIV ANTWERP, BELGIUM DEPARTMENT OF ONCOLOGY-PATHOLOGY, SWEDEN SAPIENZA UNIV ROME, ITALY UNIVERSITA DEGLI STUDI DI MILANO, ITALY UNIV URBINO CARLO BO, ITALY UNIV FRIBOURG, SWITZERLAND DANISH CANCER SOCIETY RESEARCH CENTER, DENMARK UNIV CALIFORNIA, USA WASHINGTON UNIV SCHOOL OF MEDICINE, USA KU LEUVEN, BELGIUM BOSTON UNIVERSITY, USA IFOM, ITALY UNIV COLORADO ANSCHUTZ MEDICAL CAMPUS, USA UNIV BORDEAUX, FRANCE INSTITUTO DE FISIOLOGIA CELULAR, MEXICO MEDICAL UNIV SOUTH CAROLINA, USA UNIV MELBOURNE, AUSTRALIA UNIV BUENOS AIRES, ARGENTINA L.N.C.I.B. LABORATORIO NAZIONALE CONSORZIO INTERUNIVERSITARIO BIOTECNOLOGIE, ITALY UNIV ZAGREB SCHOOL OF MEDICINE, CROATIA HOSPITAL FOR SICK CHILDREN, CANADA CHINESE ACADEMY OF MEDICAL SCIENCES & PEKING UNION MEDICAL COLLEGE, CHINA VIRGINIA COMMONWEALTH UNIVERSITY, USA CENTRE FOR CANCER BIOLOGY, AUSTRALIA DIVISION OF DEVELOPMENTAL BIOLOGY, USA UNIV NORTH CAROLINA AT CHAPEL HILL, USA UNIV NEW MEXICO HEALTH SCIENCES CENTER, USA INRS-IAF, CANADA BELLVITGE BIOMEDICAL RESEARCH INSTITUTE-IDIBELL, SPAIN UNIV CALIFORNIA, USA UNIV ZURICH, SWITZERLAND WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH, AUSTRALIA UNIV NAPLES “FEDERICO II”, ITALY UNIV PERUGIA, ITALY SAPIENZA UNIV ROME, ITALY PHILIPPS UNIV MARBURG, GERMANY IRCCS FOUNDATION CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, ITALY UNIV TERAMO, ITALY WESTERN UNIVERSITY, CANADA HARVARD MEDICAL SCHOOL, USA NATIONAL INSTITUTE FOR INFECTIOUS DISEASES “L. SPALLANZANI” IRCCS, ITALY NATIONAL AND KAPODISTRIAN UNIV ATHENS, GREECE UNIV CINCINNATI COLLEGE OF MEDICINE, USA UNIV CHILE, CHILE UNIV ALCALA, SPAIN ARIZONA STATE UNIVERSITY, USA SEOUL NATIONAL UNIVERSITY, KOREA UNIV MONTREAL, CANADA GOETHE UNIVERSITY, GERMANY ZHEJIANG UNIVERSITY, CHINA UNIV KANSAS MEDICAL CENTER, USA UNIV ROME LA SAPIENZA, ITALY UNIV BELGRADE, SERBIA UNIV BELGRADE, SERBIA JOHNS HOPKINS UNIV SCHOOL OF MEDICINE, USA IMPERIAL COLLEGE LONDON, UK FRIEDRICH-ALEXANDER UNIV (FAU) ERLANGEN-NURNBERG AND UNIVERSITATSKLINIKUM ERLANGEN, GERMANY WASHINGTON UNIV SCHOOL OF MEDICINE AND JOHN COCHRAN VA MEDICAL CENTER, USA UNIV MANITOBA, CANADA CENTRE DE RECHERCHE DES CORDELIERS, FRANCE UNIV CALGARY, CANADA UNIV COLIMA, MEXICO UNIV CANTERBURY, NEW ZEALAND HACETTEPE UNIVERSITY, TURKEY UNIV KENTUCKY, USA UNIV TEXAS SOUTHWESTERN MEDICAL CENTER, USA JINSHAN BRANCH OF SHANGHAI SIXTH PEOPLE'S HOSPITAL, CHINA WASHINGTON UNIV IN ST LOUIS SCHOOL OF MEDICINE, USA GOETHE UNIVERSITY, GERMANY NANJING UNIVERSITY, CHINA EMORY UNIV SCHOOL OF MEDICINE, USA UMEA UNIVERSITY, SWEDEN UNIV ARKANSAS, USA ONCOGENETIC LABORATORY, ISRAEL TONGREN HOSPITAL, CHINA UNIV BRITISH COLUMBIA, CANADA NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, CHINA CENTRAL SOUTH UNIVERSITY, CHINA CHINESE ACADEMY OF MEDICAL SCIENCES AND PEKING UNION MEDICAL COLLEGE, CHINA CARDIFF UNIVERSITY, UK CENTRO ANDALUZ DE BIOLOGIA MOLECULAR Y MEDICINA REGENERATIVA CABIMER, SPAIN SHANGHAI PROTON AND HEAVY ION CENTER, CHINA UNIV MEDICAL CENTER HAMBURG-EPPENDORF, GERMANY A.V. ZHIRMUNSKY NATIONAL SCIENTIFIC CENTER OF MARINE BIOLOGY, RUSSIAN FEDERATION FAR EASTERN FEDERAL UNIVERSITY, RUSSIAN FEDERATION DEPARTMENT OF NEUROLOGY, USA MEDICAL UNIV VIENNA, AUSTRIA UNIV COLORADO ANSCHUTZ MEDICAL CAMPUS, USA UNIV MANITOBA, CANADA UNIV COLOGNE, GERMANY UNITED ARAB EMIRATES UNIVERSITY, UAE UNIV GRAZ, AUSTRIA LONG BEACH VA AND UNIV CALIFORNIA, USA AIN SHAMS UNIVERSITY, EGYPT HOSPITAL UNIVERSITARI DE TARRAGONA JOAN XXIII, INSTITUT D’INVESTIGACIÓ SANTITÀRIA PERE VIRGILI UNIV ILLINOIS AT CHICAGO, USA FLORIDA INTERNATIONAL UNIVERSITY, USA CHILDREN’S CANCER HOSPITAL EGYPT 57357, EGYPT UNIV CAMERINO, ITALY DAMIETTA UNIVERSITY, EGYPT TECHNISCHE UNIVERSITAT DRESDEN, CZECH REPUBLIC INSTITUTO DE INVESTIGACIONES BIOMEDICAS EN RETROVIRUS Y SIDA (INBIRS), ARGENTINA UNIV SHEFFIELD, UK PHILIPPS UNIV MARBURG, GERMANY SANFORD BURNHAM PREBYS MEDICAL DISCOVERY RESEARCH INSTITUTE, USA BOGAZICI UNIVERSITY, TURKEY PFIZER, USA OSLO UNIV HOSPITAL, NORWAY UNIV BERGEN, NORWAY INSTITUTO DE INVESTIGACIONES BIOMEDICAS ALBERTO SOLS, SPAIN UNIVERSITAT ZU KOLN, GERMANY UNIV TURKU, FINLAND IRIM, FRANCE MEDICAL UNIV LODZ, POLAND SAPIENZA UNIV ROME, ITALY ISTITUTO SUPERIORE DI SANITA, ITALY KAROLINSKA INSTITUTET, SWEDEN UNIVERSIDAD NACIONAL DE CUYO, ARGENTINA MAX-PLANCK-INSTITUTE OF BIOPHYSICAL CHEMISTRY, GERMANY LA TROBE INSTITUTE FOR MOLECULAR SCIENCE, AUSTRALIA UNIVERSIDAD MIGUEL HERNANDEZ (UMH), SPAIN DRESDEN UNIV MEDICAL CENTER, GERMANY UNIV SOUTH CAROLINA SCHOOL OF MEDICINE, USA UNIV PITTSBURGH, USA UNIV CINCINNATI, USA UNIV OSLO AND AKERSHUS UNIV HOSPITAL, NORWAY SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINA THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV CHINESE MEDICINE, CHINA KING’S COLLEGE LONDON, FRANCE CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE (CIRI), FRANCE RUDOLF VIRCHOW CENTER, GERMANY SOUTH AUSTRALIAN HEALTH AND MEDICAL RESEARCH INSTITUTE, AUSTRALIA LEWIS KATZ SCHOOL OF MEDICINE AT TEMPLE UNIVERSITY, USA GUANGZHOU MEDICAL UNIVERSITY, CHINA THE FIRST HOSPITAL OF JILIN UNIVERSITY, CHINA MEDICAL SCHOOL OF ZHEJIANG UNIVERSITY, CHINA THE UNIV HONG KONG, CHINA BAYLOR COLLEGE OF MEDICINE, USA CHINESE ACADEMY OF SCIENCES, CHINA UNIV SAO PAULO (USP), BRAZIL WASHINGTON UNIV IN ST. LOUIS, USA UNIV TEXAS SOUTHWESTERN MEDICAL CENTER, USA INSTITUTE OF BIOMEDICAL RESEARCH OF BARCELONA (IIBB)-CSIC, USA COLUMBIA UNIVERSITY, USA UNIVERSITA DEL PIEMONTE ORIENTALE, ITALY UNIV SAO PAULO, BRAZIL UNIV CALIFORNIA, USA INSTITUTO DE INVESTIGACIONES MARINAS CSIC, SPAIN UNIV PADUA, ITALY UNIV PIEMONTE ORIENTALE, ITALY UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL (UFRGS), BRAZIL DANISH CANCER SOCIETY RESEARCH CENTER, DENMARK DEPARTMENT OF MOLECULAR MEDICINE, ITALY UNIVERSITA DEGLI STUDI SAPIENZA DI ROMA, ITALY CENTER FOR SYSTEMS AND THERAPEUTICS, USA NYU SCHOOL OF MEDICINE, USA VIRGINIA COMMONWEALTH UNIVERSITY, USA STATE UNIV NEW YORK, USA NORWEGIAN UNIV SCIENCE AND TECHNOLOGY, NORWAY CENTRAL UNIV TAMIL NADU, INDIA BABRAHAM INSTITUTE, UK UNIV GENOVA, ITALY MONTREAL NEUROLOGICAL INSTITUTE, CANADA UNIV PAVIA, ITALY UNIV PISA, ITALY ISTITUTO SUPERIORE DI SANITA, ITALY UNIV TEXAS MEDICAL BRANCH, USA UNIV NEBRASKA-LINCOLN, USA LABORATORY OF SEX-GENDER MEDICINE, ITALY ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, USA INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA (IST), AUSTRIA CLINICA UNIVERSIDAD DE NAVARRA, SPAIN UNIV EXTREMADURA, SPAIN KYUSHU UNIVERSITY, JAPAN TOKYO INSTITUTE OF TECHNOLOGY, JAPAN NATIONAL INSTITUTE OF NEUROSCIENCE, JAPAN TOHOKU UNIVERSITY, JAPAN GOETHE-UNIV FRANKFURT, GERMANY MONASH UNIVERSITY, AUSTRALIA JUNTENDO UNIV GRADUATE SCHOOL OF MEDICINE, TOKYO JAPAN THE UNIV CHICAGO, USA UNIV GDANSK, POLAND NEW YORK UNIV - ABU DHABI, UAE UNIV OXFORD, UK UNIVERSIDAD CASTILLA LA MANCHA, SPAIN BECKMAN RESEARCH INSTITUTE AT CITY OF HOPE, USA WEILL CORNELL MEDICAL COLLEGE, FRANCE SORBONNE UNIVERSITE, FRANCE UNIV EDINBURGH, UK UNIV TEXAS MD ANDERSON CANCER CENTER, USA MRC PROTEIN PHOSPHORYLATION AND UBIQUITYLATION UNIT, UK FOURTH MILITARY MEDICAL UNIVERSITY, CHINA CHINESE ACADEMY OF SCIENCES, CHINA HARBIN INSTITUTE OF TECHNOLOGY, CHINA SOUTH CHINA UNIV TECHNOLOGY, CHINA UNIV PITTSBURGH SCHOOL OF MEDICINE, USA UNIV PITTSBURGH SCHOOL OF MEDICINE, USA CHINESE ACADEMY OF SCIENCES CENTER FOR EXCELLENCE IN MOLECULAR AND CELLULAR SCIENCES, CHINA UNIVERSITAT DE LLEIDA, SPAIN UNIVERSIDAD DE BUENOS AIRES, ARGENTINA UNIVERSIDAD DE BUENOS AIRES, ARGENTINA NATIONAL CENTER FOR BIOTECHNOLOGY (CNB)-CSIC, SPAIN UNIVERSIDAD AUTONOMA DE MADRID, SPAIN UNIVERSIDAD AUTONOMA DE NUEVO LEON, MEXICO UNIVERSIDAD DE SALAMANCA, SPAIN DEPARTMENT OF CELL BIOLOGY AND HISTOLOGY, SPAIN DEPARTMENT OF CELL DEATH AND PROLIFERATION, SPAIN CAJAL INSTITUTE/CSIC AND CIBERNED, SPAIN KU LEUVEN, BELGIUM CENTRO DE BIOLOGIA MOLECULAR SEVERO OCHOA (CSIC-UAM), SPAIN SAPIENZA UNIV ROME, ITALY TULANE UNIVERSITY, USA UNIV BONN, GERMANY ZHEJIANG UNIV SCHOOL OF MEDICINE, CHINA UNIV MILANO, ITALY INSTITUT DE BIOLOGIE MOLECULAIRE DES PLANTES, FRANCE UNIV CLINIC FREIBURG, GERMANY MORTIMER B. ZUCKERMAN MIND BRAIN AND BEHAVIOR INSTITUTE, USA INSTITUTE FOR ANIMAL DEVELOPMENTAL AND MOLECULAR BIOLOGY, GERMANY VIRGINIA COMMONWEALTH UNIVERSITY, USA KERMAN UNIV MEDICAL SCIENCES, IRAN AUTOPHAGY RESEARCH CENTER, IRAN UNIV TORINO, ITALY KU LEUVEN, BELGIUM UNIV SUSSEX, UK SAPIENZA UNIV ROME, ITALY DEMOCRITUS UNIV THRACE, GREECE WEILL CORNELL MEDICINE, USA UNIV MANITOBA, CANADA DEPARTMENT OF FUNDAMENTAL NEUROSCIENCES, SWITZERLAND CLINIC OF NEONATOLOGY, SWITZERLAND NATIONAL INSTITUTES OF HEALTH, USA UNIV FERRARA, ITALY UNIV COIMBRA, PORTUGAL UNIV TORONTO, CANADA UNIV CALIFORNIA, USA INSERM, FRANCE UNIV COLOGNE, GERMANY UNIV SEVILLE, SPAIN LUDWIG INSTITUTE FOR CANCER RESEARCH; UNIV CALIFORNIA SAN DIEGO, USA MEDICAL UNIV WARSAW, POLAND UNIV AUCKLAND, NEW ZEALAND LUXEMBOURG INSTITUTE OF HEALTH, LUXEMBOURG CENTER OF TOXINS, BRAZIL UNIV GRONINGEN, NETHERLANDS LEIDEN UNIV MEDICAL CENTER, NETHERLANDS SHANGHAI JIAO TONG UNIVERSITY, CHINA UNIV LEON, SPAIN UNIV LA LAGUNA, SPAIN UNIV ALBERTA, CANADA UNIV ALABAMA AT BIRMINGHAM, USA THE HENRY M. JACKSON FOUNDATION, USA TECHNISCHE UNIVERSITAT MUNCHEN, GERMANY UNIVERSIDAD DE BUENOS AIRES, ARGENTINA BC CANCER, CANADA HARVARD MEDICAL SCHOOL, USA CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, SPAIN SMIDT HEART INSTITUTE, USA TEL AVIV UNIVERSITY, ISRAEL MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING, GERMANY JENA UNIV HOSPITAL, GERMANY WEILL CORNELL MEDICINE, USA UNIV TEXAS MD ANDERSON CANCER CENTER, USA UNIV THE WEST OF ENGLAND, UK FLINDERS UNIVERSITY, AUSTRALIA UNIV ALABAMA AT BIRMINGHAM, USA BOSTON UNIVERSITY, USA UNIV STRASBOURG/CNRS UPR 3572 INSTITUT DE BIOLOGIE MOLECULAIRE ET CELLULAIRE, FRANCE UNIV IOWA, USA MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING, GERMANY GERMAN INSTITUTE OF HUMAN NUTRITION, GERMANY LANZHOU UNIVERSITY, CHINA CASE WESTERN RESERVE UNIVERSITY, USA UNIV SALENTO, ITALY RESEARCH CENTER PRINCIPE FELIPE, SPAIN JOHNS HOPKINS UNIV SCHOOL OF MEDICINE, USA SCHOOL OF PHARMACY, SPAIN DALHOUSIE UNIVERSITY, CANADA DAVID GEFFEN SCHOOL OF MEDICINE AT UCLA, USA KU LEUVEN, BELGIUM JUSTUS-LIEBIG UNIVERSITY, GERMANY CENTER FOR MOLECULAR MEDICINE, USA TONGJI UNIV SCHOOL OF MEDICINE, CHINA THE UNIV SHEFFIELD, UK UNIV VIRGINIA, USA UNIV CALIFORNIA, USA INSTITUTE OF MICROBIAL TECHNOLOGY, INDIA CSIR-CENTRAL DRUG RESEARCH INSTITUTE, INDIA UNIV OSLO, NORWAY DEAKIN UNIVERSITY, AUSTRALIA MACQUARIE UNIVERSITY, AUSTRALIA UNIV CALIFORNIA, USA MEDICAL COLLEGE OF WISCONSIN, USA ICAR-INDIAN VETERINARY RESEARCH INSTITUTE, INDIA UNIV EASTERN FINLAND, FINLAND BRANDEIS UNIVERSITY, USA UNIV GDANSK, POLAND TOKAI UNIV SCHOOL OF MEDICINE, JAPAN SWEDISH AGRICULTURAL UNIV (SLU), SWEDEN HASSELT UNIVERSITY, BELGIUM UNIV SURREY, UK BARTS CANCER INSTITUTE, UK JOHNS HOPKINS UNIV BLOOMBERG SCHOOL OF PUBLIC HEALTH, USA GOETHE UNIVERSITY, GERMANY OSAKA UNIVERSITY, JAPAN ZHEJIANG UNIVERSITY, CHINA SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, USA UNIV MICHIGAN, USA THIRD DEPARTMENT OF INTERNAL MEDICINE, JAPAN DEPARTMENT OF NEUROPHYSIOLOGY, SERBIA UNIV CALIFORNIA, USA UNIV TORONTO, CANADA MONASH UNIVERSITY, AUSTRALIA TOHOKU UNIV GRADUATE SCHOOL OF MEDICINE, JAPAN UNIV MALAYA, MALAYSIA WASHINGTON UNIV SCHOOL OF MEDICINE, USA LEIBNIZ FORSCHUNGSINSTITUT FUR MOLEKULARE PHARMAKOLOGIE (FMP), GERMANY CALIFORNIA INSTITUTE OF TECHNOLOGY, USA UNIV MASSACHUSETTS MEDICAL SCHOOL, USA BULGARIAN ACADEMY OF SCIENCES, BULGARIA UNIV MINNESOTA, USA NORTHWESTERN UNIVERSITY, USA SICHUAN UNIVERSITY, CHINA JINAN UNIVERSITY, CHINA DEPARTMENT OF IMMUNOLOGY, USA UNIV CHICAGO, USA D'YOUVILLE COLLEGE, USA UNIV INNSBRUCK, NETHERLANDS NATIONAL INSTITUTES OF HEALTH, USA UNIV GLASGOW, UK UNIV COLLEGE LONDON, UK UNIVERSIDADE FEDERAL DE SAO CARLOS, BRAZIL INSTITUTO DE INVESTIGACION SANITARIA DE NAVARRA (IDISNA), SPAIN UNIV BORDEAUX, FRANCE UNIV BARCELONA, SPAIN INRA, CHINA UNIV LLEIDA, SPAIN UNIV PAIS VASCO EHU, SPAIN CENTENARY INSTITUTE, AUSTRALIA UNIV CHILE, USA UNIV BERN, SWITZERLAND KYUSHU UNIVERSITY, JAPAN UT SOUTHWESTERN MEDICAL CENTER, USA THEORETICAL DIVISION, USA UNIV WATERLOO, CANADA UNIV HONG KONG, CHINA NATIONAL UNIV SINGAPORE, SINGAPORE UNIV NORTH CAROLINA AT CHAPEL HILL, USA YALE UNIVERSITY, USA SWEDISH UNIV AGRICULTURAL SCIENCES (SLU) AND LINNEAN CENTER FOR PLANT BIOLOGY, SWEDEN UNIV NICE, FRANCE GERMAN INSTITUTE OF HUMAN NUTRITION POTSDAM-REHBRUECKE (DIFE), GERMANY UNIV HELSINKI, FINLAND UNIV BIRMINGHAM, UK KYUNGPOOK NATIONAL UNIVERSITY, KOREA KAOHSIUNG MEDICAL UNIVERSITY, TAIWAN UNIV COLOGNE, GERMANY EUROPEAN MOLECULAR BIOLOGY LABORATORY, GERMANY UNIV TEXAS SOUTHWESTERN MEDICAL CENTER, USA CHUNG SHAN MEDICAL UNIVERSITY, TAIWAN NATIONAL CHIAO-TUNG UNIVERSITY, TAIWAN UNIV PLYMOUTH, UK ANHUI UNIV SCIENCE AND TECHNOLOGY, CHINA SOOCHOW UNIVERSITY, CHINA UNIV TEXAS SOUTHWESTERN MEDICAL CENTER, USA SOUTHERN MEDICAL UNIVERSITY, GUANGDONG NATIONAL TSING HUA UNIVERSITY, TAIWAN NORTHWEST A&F UNIVERSITY, CHINA SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE, CHINA STATE UNIV NEW YORK, USA SICHUAN UNIVERSITY, CHINA NEW YORK UNIV SCHOOL OF MEDICINE, USA SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE, CHINA UNIV SYDNEY, AUSTRALIA WENZHOU MEDICAL UNIVERSITY, CHINA HUAZHONG UNIV SCIENCE AND TECHNOLOGY, CHINA CHONGQING UNIVERSITY, CHINA THE SECOND AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIVERSITY, CHINA ZHEJIANG UNIV SCHOOL OF MEDICINE, CHINA III. 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LOUIS, USA UMBC, USA UNIV VIENNA, AUSTRIA HARVARD MEDICAL SCHOOL, USA EUROPEAN INSTITUTE OF ONCOLOGY (IEO) IRCCS, ITALY KU LEUVEN, BELGIUM INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA (INIA), SPAIN LABORATORIO DE GENETICA BIOQUIMICA (LAGENBIO), SPAIN UNIV LAS PALMAS DE GRAN CANARIA, SPAIN INSTITUTO DE INVESTIGACIONES BIOMEDICAS “ALBERTO SOLS”, SPAIN CELL AND DEVELOPMENTAL BIOLOGY CENTER, USA UNIV CAMBRIDGE, UK NATIONAL INSTITUTES OF HEALTH, USA CENTRO DE INVESTIGACION Y ASISTENCIA EN TECNOLOGIA Y DISENO DEL ESTADO DE JALISCO, MÉXICO ALBERT EINSTEIN COLLEGE OF MEDICINE, USA VALL D'HEBRON RESEARCH INSTITUTE-UAB/NEURODEGENERATIVE DISEASES GROUP, SPAIN UNIV SAO PAULO, BRAZIL LABORATORY OF IMMUNOENDOCRINOLOGY, BRAZIL UNIVERSIDADE ANHANGUERA DE SAO PAULO, BRAZIL UNIVERSITA CATTOLICA DEL SACRO CUORE, ITALY INSTITUT JEAN-PIERRE BOURGIN, FRANCE UNIV MINNESOTA, USA UNIVERSITA DEGLI STUDI DI MILANO, ITALY UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO, MEXICO MRC LABORATORY OF MOLECULAR BIOLOGY, UK UNIV ROME “SAPIENZA”, ITALY CENTER FOR GENDER-SPECIFIC MEDICINE, ITALY BIODONOSTIA HEALTH RESEARCH INSTITUTE, SPAIN KYOTO PREFECTURAL UNIV MEDICINE, JAPAN CHU CLERMONT-FERRAND, FRANCE UNIV CHIETI-PESCARA, ITALY UNIV CALIFORNIA, USA CONACYT - CENTRO DE INVESTIGACION BIOMEDICA DE ORIENTE, MEXICO IRCCS “CASA SOLLIEVO DELLA SOFFERENZA”, ITALY SAPIENZA UNIV ROME, ITALY UNIV TEXAS HEALTH SCIENCE CENTER AT HOUSTON, USA CLEVELAND CLINIC, USA UNIV ARKANSAS FOR MEDICAL SCIENCES, USA UNIV COLLEGE CORK, IRELAND ACADEMIC DECENCY, USA MAYO CLINIC, USA TRANSLATIONAL STEM CELL BIOLOGY METABOLISM PROGRAM, FINLAND DEPARTMENT OF ANATOMY, FINLAND PSL RESEARCH UNIVERSITY, FRANCE SPROTT CENTRE FOR STEM CELL RESEARCH, CANADA UNIV SZEGED, HUNGARY UNIV ARKANSAS FOR MEDICAL SCIENCES AND CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM, USA UNIV AMSTERDAM, NETHERLANDS LEIDEN UNIVERSITY, USA UIT THE ARCTIC UNIV NORWAY, NORWAY CHILDRENS' HOSPITAL, GERMANY ANHUI PROVINCE KEY LABORATORY OF MEDICAL PHYSICS AND TECHNOLOGY, CHINA LABORATORY OF CELL BIOLOGY, BRAZIL INDIAN INSTITUTE OF TECHNOLOGY DELHI, INDIA UNIV CINCINNATI, USA UNIV PRETORIA, SOUTH AFRICA LABORATOIRE D'OPTIQUE ET BIOSCIENCES, FRANCE UNIV NEW MEXICO, USA CARITE-UNIVERSITAETSMEDIZIN BERLIN, GERMANY RUPRECHT-KARLS UNIV HEIDELBERG, GERMANY INSTITUT JEAN-PIERRE BOURGIN, FRANCE UNIV DUISBURG-ESSEN, GERMANY TIANJIN MEDICAL UNIVERSITY, CHINA INSERM INSTITUTE OF METABOLIC AND CARDIOVASCULAR DISEASES (I2MC), FRANCE SHANDONG UNIVERSITY, CHINA FONDAZIONE IRCCS CASA SOLLIEVO DELLA SOFFERENZA, ITALY HIROSAKI UNIV GRADUATE SCHOOL OF MEDICINE, UK NATIONAL MEDICINES INSTITUTE, POLAND UNIV WASHINGTON SCHOOL OF MEDICINE, USA UNIV WASHINGTON, USA SAGE THERAPEUTICS, USA EUROPEAN NEUROSCIENCE INSTITUTE (ENI) - A JOINT INITIATIVE OF THE UNIV MEDICAL CENTER GOTTINGEN AND THE MAX PLANCK SOCIETY, GERMANY SWEDISH UNIV AGRICULTURAL SCIENCES AND LINNEAN CENTER FOR PLANT BIOLOGY, GERMANY KASHAN UNIV MEDICAL SCIENCES, IRAN TEHRAN UNIV MEDICAL SCIENCES, IRAN MACQUARIE UNIVERSITY, AUSTRALIA INDIAN INSTITUTE OF TECHNOLOGY JODHPUR, INDIA AMRITA VISHWA VIDYAPEETHAM, INDIA UNIV NEBRASKA MEDICAL CENTER, USA UNIV CAMPANIA L. 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DEPARTMENT OF PHARMACOLOGY, USA TRINITY COLLEGE DUBLIN, IRELAND ARMY MEDICAL UNIV (THIRD MILITARY MEDICAL UNIVERSITY), CHINA UNIV FERRARA, ITALY NATIONAL HOSPITAL FOR PARAPLEGICS (SESCAM), SPAIN EAST TENNESSEE STATE UNIVERSITY, USA ICMR-VECTOR CONTROL RESEARCH CENTER, INDIA UNIV KANSAS SCHOOL OF MEDICINE, USA NEW YORK UNIV SCHOOL OF MEDICINE, USA FACULDADE DE MEDICINA E CIENCIAS BIOMEDICAS, PORTUGAL DUKE UNIVERSITY, USA UNIV SPLIT, CROATIA DOSHISHA UNIV GRADUATE SCHOOL OF BRAIN SCIENCE, JAPAN CENTER FOR MOLECULAR BIOLOGY OF HEIDELBERG UNIV (ZMBH) AND GERMAN CANCER RESEARCH CENTER (DKFZ), GERMANY DANISH CANCER SOCIETY RESEARCH CENTER, DENMARK TRINITY COLLEGE DUBLIN, IRELAND DAVID GEFFEN SCHOOL OF MEDICINE AT UCLA, USA UNIV MESSINA, ITALY HOPP CHILDREN'S CANCER CENTER HEIDELBERG (KITZ), GERMANY NATIONAL INSTITUTE OF INFECTIOUS DISEASES, JAPAN UNIV PARIS, FRANCE UNIV ICELAND, ICELAND HOLLINGS CANCER CENTER, USA EWHA WOMANS UNIVERSITY, KOREA CHOSUN UNIVERSITY, KOREA YONSEI UNIVERSITY, KOREA YAMAGUCHI UNIVERSITY, JAPAN HYOGO COLLEGE OF MEDICINE, JAPAN UNIV PERUGIA, ITALY STANFORD UNIVERSITY, USA OSAKA UNIVERSITY, JAPAN TOKYO MEDICAL AND DENTAL UNIVERSITY, JAPAN KYOTO UNIV ADVANCED SCIENCE, JAPAN UNIV PORTO, PORTUGAL AMGEN INC., USA UNIV CALIFORNIA, USA RUTGERS UNIVERSITY, USA UNIV DEFENSE, CZECH REPUBLIC THE CHINESE UNIV HONG KONG, CHINA THE UNIV ILLINOIS AT CHICAGO COLLEGE OF MEDICINE, USA PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE, CHILE UNIV PENNSYLVANIA PERELMAN SCHOOL OF MEDICINE AND DIVISION OF NEUROLOGY, USA SUEZ CANAL UNIVERSITY, EGYPT UNIV WISCONSIN-MADISON, USA GERMAN INSTITUTE OF HUMAN NUTRITION POTSDAM-REHBRUECKE, GERMANY DEPARTMENT OF PATHOPHYSIOLOGY AND TRANSPLANTATION, ITALY UNIV SOUTHERN CALIFORNIA, USA UNIV MEDICAL CENTER GOTTINGEN, UK OSLO UNIV HOSPITAL AND UNIV OSLO, NORWAY ISTANBUL UNIVERSITY-CERRAHPASA, TURKEY TEXAS BIOMEDICAL RESEARCH INSTITUTE, USA BAYLOR COLLEGE OF MEDICINE, USA UNIV NAPLES FEDERICO II, ITALY UNIV PARIS, FRANCE FONDAZIONE IRCCS OSPEDALE SAN RAFFAELE, ITALY UNIV SAO PAULO, BRAZIL UNIV ROME TOR VERGATA, ITALY UNIV GOETHE FRANKFURT, GERMANY SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINA AFFILIATED HOSPITAL OF GUANGDONG MEDICAL UNIVERSITY, CHINA BETH ISRAEL DEACONESS MEDICAL CENTER, USA NATIONAL CENTER OF BIOMEDICAL ANALYSIS, CHINA THE CHILDREN'S HOSPITAL OF PHILADELPHIA, USA UNIV PITTSBURGH MEDICAL CENTER, USA UNIV ALBERTA, CANADA UNIV SALENTO, ITALY DANISH CANCER SOCIETY RESEARCH CENTER, DENMARK MAX PERUTZ LABS, AUSTRIA QUADRAM INSTITUTE BIOSCIENCE, UK WAKSMAN INSTITUTE, USA DONG-A UNIV MEDICAL SCHOOL, KOREA MEDICAL COLLEGE OF WISCONSIN, USA INCHEON NATIONAL UNIVERSITY, KOREA YONSEI UNIVERSITY, KOREA CHONNAM NATIONAL UNIVERSITY, KOREA CHONBUK NATIONAL UNIVERSITY, KOREA BEN GURION UNIV THE NEGEV, ISRAEL KU LEUVEN, BELGIUM SANOFI, FRANCE MAYO CLINIC, USA VA SAN DIEGO HEALTHCARE SYSTEMS AND UNIV CALIFORNIA, USA INTERNAL MEDICINE 1, GERMANY IRCM, FRANCE UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO, MÉXICO UNIVERSIDAD DE CHILE, CHILE FRIEDRICH-LOEFFLER-INSTITUT, GERMANY THE FOURTH MILITARY MEDICAL UNIVERSITY, CHINA WEIZMANN INSTITUTE OF SCIENCE, ISRAEL CENTRO DE INVESTIGACIONES BIOLOGICAS CSIC, SPAIN SUN YAT-SEN UNIVERSITY, CHINA UNIV PADOVA, ITALY FONDAZIONE G. PASCALE, ITALY UNIV COIMBRA, PORTUGAL UNIVERSIDADE FEDERAL DE SAO PAULO, BRAZIL SAO PAULO STATE UNIVERSITY, BRAZIL UNIV MELBOURNE, AUSTRALIA UNIV GRANADA, SPAIN UNIV NEBRASKA MEDICAL CENTER, USA STATE UNIV NEW YORK, USA UNIVERSITA DEGLI STUDI DI MILANO, ITALY UNIV CALABRIA, ITALY BARUCH S. BLUMBERG INSTITUTE, USA NATIONAL JEWISH HEALTH AND THE UNIV COLORADO, USA UNIV OSLO, NORWAY HEALTH AND MEDICAL UNIVERSITY, GERMANY ULM UNIVERSITY, GERMANY WASHINGTON UNIVERSITY, USA THIRD MILITARY MEDICAL UNIVERSITY, CHINA VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY, USA AIX MARSEILLE UNIVERSITE, CHINA KAROLINSKA INSTITUTET, SWEDEN CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), SALAMANCA. SPAIN TEL AVIV UNIVERSITY, ISRAEL THE UNIV TEXAS MD ANDERSON CANCER CENTER, USA RADBOUD UNIV MEDICAL CENTER, NETHERLANDS RUHR-UNIVERSITAT BOCHUM, GERMANY UNIV PAIS VASCO EHU, SPAIN UNIV COLOGNE, GERMANY MOSCOW STATE UNIVERSITY, RUSSIA UCL QUEEN SQUARE INSTITUTE OF NEUROLOGY, UK MONASH BIOMEDICINE DISCOVERY INSTITUTE AND MONASH UNIVERSITY, AUSTRALIA GEORG-AUGUST UNIV GOTTINGEN, GERMANY BUCHMANN INSTITUTE & INSTITUTE OF BIOCHEMISTRY II, GERMANY CANCER RESEARCH CENTER OF TOULOUSE, FRANCE MAHIDOL UNIVERSITY, THAILAND ERASMUS UNIV MEDICAL CENTER, NETHERLANDS THE HOSPITAL FOR SICK CHILDREN, CANADA ST. JUDE CHILDREN’S RESEARCH HOSPITAL, USA UNIV OXFORD, UK UNIV CALIFORNIA, USA UNIV IOWA, USA JAGIELLONIAN UNIVERSITY, POLAND TEMPLE UNIVERSITY, USA EBERHARD KARLS UNIV TUBINGEN, GERMANY UNIV CYPRUS, CYPRUS LIFELONG HEALTH, AUSTRALIA UNIV WISCONSIN-MADISON, USA DALHOUSIE UNIVERSITY, CANADA NATIONAL CENTER FOR CELL SCIENCE, INDIA CURML, SWITZERLAND CHINESE ACADEMY OF SCIENCES, CHINA LANZHOU UNIVERSITY, CHINA ZHEJIANG UNIVERSITY, CHINA CHINA PHARMACEUTICAL UNIVERSITY, CHINA SANOFI, USA UNIV WATERLOO, CANADA INSTITUTO DE INVESTIGACIONES BIOMEDICAS EN RETROVIRUS Y SIDA, ARGENTINA UNIV PITTSBURGH, USA DARTMOUTH COLLEGE, USA BOSTON UNIVERSITY, USA TEHRAN UNIV MEDICAL SCIENCES, IRAN PENN STATE UNIV COLLEGE OF MEDICINE, USA UNIV ALABAMA AT BIRMINGHAM, USA JOHANN WOLFGANG GOETHE-UNIVERSITY, GERMANY UNIV BIRMINGHAM, UK MRC LABORATORY OF MOLECULAR BIOLOGY, UK INDIAN INSTITUTE OF SCIENCE, INDIA SCHOOL OF MEDICINE, CHINA BAYLOR COLLEGE OF MEDICINE, USA THE UNIV KANSAS CANCER CENTER, USA ALL INDIA INSTITUTE OF MEDICAL SCIENCES, INDIA UNIV SOUTHAMPTON, UK JOHNS HOPKINS UNIV SCHOOL OF MEDICINE, USA UNIV SOUTH CAROLINA SCHOOL OF MEDICINE, USA WASHINGTON UNIV SCHOOL OF MEDICINE, USA JOHNS HOPKINS UNIVERSITY, USA JOHANNES GUTENBERG UNIVERSITY-MAINZ, GERMANY HEINRICH HEINE UNIV DUSSELDORF, GERMANY THE UNIV TEXAS MD ANDERSON CANCER CENTER, USA MAX PLANCK INSTITUTE OF PSYCHIATRY, GERMANY UNIV VIENNA, AUSTRIA KAROLINSKA INSTITUTET, SWEDEN WRIGHT STATE UNIVERSITY, USA UNIV WYOMING, USA QINGDAO AGRICULTURAL UNIVERSITY, CHINA IFREMER, FRANCE UNIV CALIFORNIA, USA BOTUCATU MEDICAL SCHOOL, BRAZIL INSTITUT DE GENETIQUE ET DE BIOLOGIE MOLECULAIRE ET CELLULAIRE, FRANCE THE OHIO STATE UNIVERSITY, USA THOMAS JEFFERSON UNIVERSITY, USA JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE, SPAIN DEMOCRITUS UNIV THRACE, GREECE REDOX SIGNALING AND OXIDATIVE STRESS GROUP, DENMARK UNIV PADUA, ITALY MIDDLESEX UNIVERSITY, UK INSERM U1065, FRANCE BAYLOR COLLEGE OF MEDICINE, USA FEDERAL UNIV ABC (UFABC), BRAZIL UNIV CAMPINAS (UNICAMP), BRAZIL UNIV BARCELONA, SPAIN KANSAS CITY UNIV MEDICINE AND BIOSCIENCES, USA UNIV GOETHE FRANKFURT, GERMANY UNIV GDANSK, POLAND DEPARTMENT OF MEDICINE AND SURGERY, PERUGIA ITALY UNIVERSITA DEGLI STUDI DI CATANIA, ITALY CONICET-UNIVERSIDAD NACIONAL DE CUYO, ARGENTINA INSERM U1151, FRANCE NAPLES UNIVERSITY, ITALY UNIV WURZBURG, GERMANY KIEL UNIV AND UNIV HOSPITAL SCHLESWIG-HOLSTEIN, GERMANY GEORGETOWN UNIVERSITY, USA COLUMBIA UNIVERSITY, USA UNIV ILLINOIS, USA NORMANDY UNIVERSITY, FRANCE UNIV SHERBROOKE, CANADA SECTION ON EUKARYOTIC DNA REPLICATION, USA UNIV SEVILLE. SCHOOL OF PHARMACY, SPAIN UNIV CAMBRIDGE, UK LOMONOSOV MOSCOW STATE UNIVERSITY, RUSSIA UNIV MEDICAL CENTER EPPENDORF, GERMANY CHARLES UNIVERSITY, CZECH REPUBLIC MANNHEIM UNIV APPLIED SCIENCES, GERMANY FONDAZIONE IRCCS ISTITUTO NEUROLOGICO CARLO BESTA, ITALY AUSTRALIAN REGENERATIVE MEDICINE INSTITUTE, AUSTRALIA UNIV OTTAWA, CANADA NATIONAL RESEARCH COUNCIL, ITALY STAZIONE ZOOLOGICA “ANTON DOHRN”, ITALY UNIV CALABRIA, ITALY N.N. BLOKHIN NATIONAL MEDICAL RESEARCH CENTER OF ONCOLOGY, RUSSIA CANCER RESEARCH UK BEATSON INSTITUTE, UK UNIV SEOUL, KOREA UNIV PITTSBURGH MEDICAL CENTER, USA CONCORDIA UNIVERSITY, CANADA ERNST-RUSKA CENTRE FOR MICROSCOPY AND SPECTROSCOPY WITH ELECTRONS (ER-C-3/STRUCTURALBIOLOGY), GERMANY SAITAMA UNIVERSITY, JAPAN RUTGERS NEW JERSEY MEDICAL SCHOOL, USA OREGON STATE UNIVERSITY, USA MASHHAD UNIV MEDICAL SCIENCES, IRAN BOSTON CHILDREN'S HOSPITAL AND HARVARD MEDICAL SCHOOL, USA UNIV SOUTH CAROLINA, USA UNIV SYDNEY, AUSTRALIA INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA), SPAIN UNIV TOYAMA, JAPAN KYOTO UNIVERSITY, JAPAN THE UNIV TOKYO, JAPAN UNIV HELSINKI AND HELSINKI UNIV HOSPITAL, FINLAND FLORIDA STATE UNIVERSITY, USA INSTITUT HOSPITAL DEL MAR D'INVESTIGACIONS MEDIQUES (IMIM), SPAIN AGRICULTURAL BIOTECHNOLOGY RESEARCH INSTITUTE OF IRAN (ABRII), IRAN UNIV MINHO, PORTUGAL CABD/CSIC/UNIVERSIDAD PABLO DE OLAVIDE, SPAIN UNIV MALAGA, SPAIN IMPERIAL COLLEGE LONDON, UK INRS-IAF, CANADA WEILL-CORNELL, USA CENTRE FOR INNOVATIVE BIOMEDICINE AND BIOTECHNOLOGY, PORTUGAL UNIV CAMERINO, ITALY UNIV GLASGOW, UK INSTITUTO DE BIOMEDICINA DE VALENCIA, SPAIN JAWAHARLAL NEHRU UNIVERSITY, INDIA INSTITUTE FOR STEM CELL SCIENCE & REGENERATIVE MEDICINE (INSTEM), INDIA UNIV MARYLAND SCHOOL OF MEDICINE, USA UNIV BIRMINGHAM, UK HEALTH RESEARCH INSTITUTE GERMANS TRIAS I PUJOL, SPAIN UNIV DELHI SOUTH CAMPUS, INDIA FOLKHALSAN RESEARCH CENTER, FINLAND MAYO CLINIC, USA NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES, INDIA DUKE UNIVERSITY, USA GOETHE UNIVERSITY, GERMANY UNIV NOTRE DAME, USA UCL QUEEN SQUARE INSTITUTE OF NEUROLOGY, UK UNIV HOSPITAL AND UNIV ZURICH, SWITZERLAND UNIV CALGARY, CANADA DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, USA AMSTERDAM UNIV MEDICAL CENTERS LOCATION VUMC, NETHERLANDS UNIV KAISERSLAUTERN, GERMANY IRCCS SAN RAFFAELE SCIENTIFIC INSTITUTE, ITALY CENTRO DI RIFERIMENTO ONCOLOGICO, ITALY MEDICAL UNIV GRAZ, AUSTRIA UNIV GRENOBLE ALPES AND INSERM U1055, FRANCE MEDICAL UNIV INNSBRUCK, AUSTRIA HANNOVER MEDICAL SCHOOL, GERMANY NATIONAL INSTITUTES OF HEALTH, USA RUHR-UNIV BOCHUM, GERMANY GERMAN CENTER FOR NEURODEGENERATIVE DISEASES, GERMANY RESEACH CENTER BORSTEL, GERMANY JOHANNES KEPLER UNIV LINZ, AUSTRIA INSTITUTO DE INVESTIGACIONES EN INGENIERIA GENETICA Y BIOLOGIA MOLECULAR DR. HECTOR N. TORRES, ARGENTINA INSTITUTO DE INVESTIGACIONES EN INGENIERIA GENETICA Y BIOLOGIA MOLECULAR DR. HECTOR N. TORRES, ARGENTINA MAYO CLINIC, USA TECHNISCHE UNIVERSITAT DRESDEN, GERMANY UNIV WUERZBURG, GERMANY UNIV NATURAL RESOURCES AND LIFE SCIENCES, AUSTRIA MAYO CLINIC, USA UNIV LUXEMBOURG, LUXEMBOURG FORSCHUNGSZENTRUM JULICH, GERMANY UNIV CAMPANIA L. VANVITELLI, ITALY DEPARTMENT OF MEDICAL AND SURGICAL SCIENCES AND BIOTECHNOLOGIES, ITALY RUTGERS BIOMEDICAL AND HEALTH SCIENCES, USA NATIONAL RESEARCH COUNCIL, ITALY HELMHOLTZ CENTRE FOR INFECTION RESEARCH, GERMANY ALBERT EINSTEIN COLLEGE OF MEDICINE, USA INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA), SPAIN RICE UNIVERSITY, USA UNIV ILLINOIS AT CHICAGO, USA UNIV OSLO, NORWAY UNIV PAU ET DES PAYS DE L’ADOUR, FRANCE CEDARS-SINAI MEDICAL CENTER, USA PENNSYLVANIA STATE UNIVERSITY, USA ALPERT MEDICAL SCHOOL OF BROWN UNIVERSITY/RHODE ISLAND HOSPITAL, USA IOWA STATE UNIVERSITY, USA DOKUZ EYLUL UNIVERSITY, TURKEY UNIV ALBERTA, CANADA UNIV ROCHESTER MEDICAL CENTER, USA JOHNS HOPKINS UNIV SCHOOL OF MEDICINE, USA INDIAN INSTITUTE OF SCIENCE, INDIA SHENZHEN UNIV HEALTH SCIENCE CENTER, CHINA UNIV ALABAMA AT BIRMINGHAM, USA UNIV WASHINGTON, USA SOOCHOW UNIVERSITY, CHINA FREIE UNIVERSITAET BERLIN, GERMANY JOHNS HOPKINS UNIVERSITY, USA UNIV PENNSYLVANIA, USA DIVISION OF STEM CELL AND GENE THERAPY RESEARCH, INDIA THOMAS JEFFERSON UNIVERSITY, USA WOMEN AND INFANTS HOSPITAL OF RHODE ISLAND-WARREN ALPERT MEDICAL SCHOOL OF BROWN UNIVERSITY, USA UNIV MACAU, CHINA THE UNIV HONG KONG, CHINA NANJING AGRICULTURAL UNIVERSITY, CHINA SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE, CHINA TOTAL TOXICOLOGY LABS, USA SOOCHOW UNIVERSITY, CHINA FRALIN BIOMEDICAL RESEARCH INSTITUTE AT VTC, USA INDIANA UNIV SCHOOL OF MEDICINE, USA VAN ANDEL INSTITUTE, USA FUDAN UNIVERSITY, CHINA JUNTENDO UNIV GRADUATE SCHOOL OF MEDICINE, JAPAN NATIONAL CHUNG-HSING UNIVERSITY, TAIWAN JIKEI UNIV SCHOOL OF MEDICINE, JAPAN TOKYO MEDICAL AND DENTAL UNIVERSITY, JAPAN TOHOKU UNIVERSITY, JAPAN GEISEL SCHOOL OF MEDICINE AT DARTMOUTH, USA KOBE UNIV GRADUATE SCHOOL OF MEDICINE, JAPAN MACS - AGHARKAR RESEARCH INSTITUTE, INDIA MAYO CLINIC COLLEGE OF MEDICINE, USA NATIONAL SUN YAT-SEN UNIVERSITY, TAIWAN HUAZHONG UNIV SCIENCE AND TECHNOLOGY, CHINA UNIV CALGARY, CANADA DEPARTMENT OF EXPERIMENTAL AND HEALTH SCIENCES, SPAIN UNIV PAIS VASCO EHU, SPAIN UNIVERSIDAD DE LA REPUBLICA, URUGUAY NATIONAL INSTITUTES OF HEALTH, USA DAVID GEFFEN SCHOOL OF MEDICINE AT UNIV CALIFORNIA, USA UNIV BERN, RUSSIA INSERM UMR1163, FRANCE BOSTON UNIV SCHOOL OF MEDICINE, USA WAYNE STATE UNIV SCHOOL OF MEDICINE, USA UNIV PITTSBURGH, USA POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH (PGIMER), INDIA BIOMEDICAL RESEARCH INSTITUTE OF NEW MEXICO, USA CSIR-NATIONAL PHYSICAL LABORATORY, INDIA UNIV PITTSBURGH SCHOOL OF MEDICINE, USA SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES, INDIA NORTH DAKOTA STATE UNIVERSITY, USA NATIONAL JEWISH HEALTH, USA MASARYK UNIVERSITY, CZECH REPUBLIC WASHINGTON STATE UNIVERSITY, USA EDINBURGH CANCER RESEARCH UK CENTRE, UK DONG-A UNIVERSITY, KOREA LOMONOSOV MOSCOW STATE UNIVERSITY, RUSSIA INDIAN INSTITUTE OF TECHNOLOGY INDORE, INDIA SHANDONG UNIVERSITY, CHINA KOREA UNIVERSITY, KOREA GUANGZHOU UNIV CHINESE MEDICINE, CHINA UNIV COLORADO ANSCHUTZ MEDICAL CAMPUS, USA HUBEI KEY LABORATORY OF CELL HOMEOSTASIS, CHINA MASSACHUSETTS GENERAL HOSPITAL AND HARVARD MEDICAL SCHOOL, USA UNIV GUELPH, CANADA UNIV CALIFORNIA, USA DEPARTMENT OF CLINICAL PSYCHOPHARMACOLOGY AND NEUROTOXICOLOGY, INDIA UNIV KENTUCKY, USA INSTITUTE OF MOLECULAR BIOLOGY AND PATHOLOGY, ITALY UNIV WESTERN ONTARIO, CANADA UNIV OSLO, NORWAY UNIV BONN, GERMANY BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS, GREECE UNIV CALIFORNIA, USA UNIV ERLANGEN NURNBERG, GERMANY OSLO UNIV HOSPITAL, NORWAY TECHNISCHE UNIVERSITAT DRESDEN, GERMANY JOZEF STEFAN INSTITUTE, SLOVENIA UNIV MEDICAL CENTER HAMBURG-EPPENDORF, GERMANY HEINRICH-HEINE-UNIVERSITY, GERMANY IRCCS FONDAZIONE SANTA LUCIA, ITALY THE OHIO STATE UNIVERSITY, USA UNIV CALIF SAN DIEGO, USA PEKING UNION MEDICAL COLLEGE AND CHINESE ACADEMY OF MEDICAL SCIENCES, CHINA INSTITUTO OSWALDO CRUZ, BRAZIL CASE WESTERN RESERVE UNIV SCHOOL OF MEDICINE, USA RUTGERS UNIVERSITY, USA UNIV MADRAS, INDIA KOLLING INSTITUTE, AUSTRALIA HANGZHOU NORMAL UNIVERSITY, CHINA IOWA STATE UNIVERSITY, USA UNIV NEBRASKA LINCOLN, USA UNIV ILLINOIS AT CHICAGO, USA SHANGHAI JIAO TONG UNIVERSITY, CHINA WUHAN UNIVERSITY, CHINA ZHEJIANG UNIVERSITY, CHINA CANCER INSTITUTE OF THE SECOND AFFILIATED HOSPITAL AND INSTITUTE OF TRANSLATIONAL MEDICINE, CHINA UNIV TENNESSEE HEALTH SCIENCE CENTER, USA EXPERIMENTAL PHYSIOPATHOLOGY, BRAZIL SWEDISH UNIV AGRICULTURAL SCIENCES, SWEDEN UNIV PENNSYLVANIA, USA UNIV MISSOURI, USA TOKAI UNIV SCHOOL OF MEDICINE, JAPAN YORK UNIVERSITY, CANADA UNIV UTAH, USA HONG KONG BAPTIST UNIVERSITY, CHINA OHIO MUSCULOSKELETAL AND NEUROLOGICAL INSTITUTE (OMNI) AND DEPARTMENT OF BIOMEDICAL SCIENCES, USA ISTITUTO SUPERIORE DI SANITA, ITALY CHARITE UNIV MEDICINE BERLIN, GERMANY THE UNIV TEXAS HEALTH SCIENCE CENTER AT HOUSTON, USA CHENGDU MEDICAL COLLEGE, CHINA UNIV GLASGOW, UK PENN STATE UNIV COLLEGE OF MEDICINE, USA VIT UNIVERSITY, INDIA THE CHINESE UNIV HONG KONG, CHINA INSERM UNIT 1195 - UNIV PARIS SACLAY, FRANCE TOKYO MEDICAL AND DENTAL UNIV (TMDU), JAPAN NATIONAL NEUROSCIENCE INSTITUTE, SINGAPORE KEY LABORATORY OF ORAL BIOMEDICINE MINISTRY OF EDUCATION, CHINA THE STATE KEY LABORATORY BREEDING BASE OF BASIC SCIENCE OF STOMATOLOGY (HUBEI-MOST), CHINA KYOTO PREFECTURAL UNIV MEDICINE, JAPAN RIKEN CENTER FOR BRAIN SCIENCE, JAPAN HUBEI UNIV TECHNOLOGY, CHINA STATE KEY LABORATORY OF MEMBRANE BIOLOGY, CHINA JUNTENDO UNIV GRADUATE SCHOOL OF MEDICINE, JAPAN HARVARD MEDICAL SCHOOL, USA UNIV MEDICINE GOETTINGEN, GERMANY FOUNDATION FOR RESEARCH AND TECHNOLOGY-HELLAS, GREECE DUKE UNIVERSITY, USA UNIV NORTH CAROLINA, USA NASONOVA RESEARCH INSTITUTE OF RHEUMATOLOGY, RUSSIA CARDIFF UNIVERSITY, UK GOETHE-UNIVERSITY, GERMANY INSERM U955, FRANCE CHULALONGKORN UNIVERSITY, THAILAND UNIV LIVERPOOL, UK CENTRO DE INVESTIGACIONES BIOLOGICAS MARGARITA SALAS, SPAIN CARL VON OSSIETZKY UNIV OLDENBURG, GERMANY UNIV GENOVA, ITALY UNIV KANSAS MEDICAL CENTER, USA UNIV NEBRASKA MEDICAL CENTER, USA UNIV COLORADO SCHOOL OF MEDICINE, USA CSIR-INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY, INDIA HANNOVER MEDICAL SCHOOL, GERMANY UNIV MEDICAL CENTER GOTTINGEN, GERMANY SOUTH CHINA AGRICULTURAL UNIVERSITY, CHINA UNIV HOSPITAL OF BONN, GERMANY UNIV ANTWERP, BELGIUM CONCORDIA UNIVERSITY, CANADA WAYNE STATE UNIV SCHOOL OF MEDICINE, USA UNIV OVIEDO, SPAIN ZHEJIANG UNIVERSITY, CHINA NORTHWESTERN UNIVERSITY, USA CENTRE DE RECHERCHE DES CORDELIERS, FRANCE NAGOYA UNIV GRADUATE SCHOOL OF MEDICINE, JAPAN UNIV BELGRADE, SERBIA UNIV FEDERICO II OF NAPLES, ITALY UNIVERSIDADE FEDERAL DO RIO DE JANEIRO, BRAZIL NATIONAL AND KAPODISTRIAN UNIV ATHENS, GREECE MEDICAL UNIV SOUTH CAROLINA, USA UNIV BERN, SWITZERLAND UNIV HONG KONG, CHINA UNIV SOUTHAMPTON, UK UNIV MONCTON, CANADA UNIV BIRMINGHAM, UK WEILL CORNELL MEDICINE, USA KOMAROV BOTANICAL INSTITUTE RAS, RUSSIAN FEDERATION NOTTINGHAM TRENT UNIVERSITY, UK UNIV OXFORD, UK INSTITUTE OF PSYCHIATRY AND NEUROLOGY, POLAND SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY, RUSSIA MIE UNIVERSITY, JAPAN UNIV OSNABRUCK, GERMANY NAGOYA CITY UNIV GRADUATE SCHOOL OF MEDICAL SCIENCES, JAPAN UNIV TUBINGEN, GERMANY UNIV MILAN, ITALY UNIV BUENOS AIRES, ARGENTINA UNIV OXFORD, UK KAROLINSKA INSTITUTE, SWEDEN UNIV MURCIA, SPAIN FUNDACION INSTITUTO LELOIR AND IIBBA, ARGENTINA INSTITUTO DE INVESTIGACIONES BIOMEDICAS ALBERTO SOLS (CSIC-UAM), SPAIN ZHEJIANG UNIVERSITY, CHINA VANDERBILT UNIV SCHOOL OF MEDICINE, USA CENTER OF TRANSLATIONAL IMMUNLOGY, NETHERLANDS GOETHE UNIVERSITY, GERMANY UNIV HOSPITALS LEUVEN, BELGIUM LABORATORY OF IMMUNOSENESCENCE AND STEM CELL METABOLISM, SWITZERLAND SCIENTIFIC INSTITUTE, ITALY INSTITUTO DE INVESTIGACIONES BIOMEDICAS “ALBERTO SOLS” (CSIC-UAM) AND CIBERER (CIBER, SPAIN HARVARD MEDICAL SCHOOL, USA UNIVERSITATSKLINIKUM ESSEN, GERMANY UNIV GRONINGEN, NETHERLANDS TUSCIA UNIVERSITY, ITALY EA 3842, FRANCE BIOMEDICAL RESEARCH FOUNDATION, GREECE INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE, FRANCE UNIV PITTSBURGH, USA WASHINGTON UNIV IN ST. LOUIS, USA SERVICE OF ENDOCRINOLOGY, SPAIN UNIV MONTPELLIER, FRANCE UNIVERSIDADE NOVA DE LISBOA, PORTUGAL UNIV HELSINKI, FINLAND VALL D'HEBRON RESEARCH INSTITUTE (VHIR)-NETWORK CENTER FOR BIOMEDICAL RESEARCH IN NEURODEGENERATIVE DISEASES (CIBERNED)-CATALAN INSTITUTION FOR RESEARCH AND ADVANCED STUDIES (ICREA), SPAIN INSTITUTE OF BIOMEDICINE OF VALENCIA, SPAIN UNIV HOSPITAL LA PAZ RESEARCH INSTITUTE (IDIPAZ), SPAIN UNIV TOULOUSE, FRANCE UNIVERSITA CATTOLICA DEL SACRO CUORE, ITALY ITALIAN INSTITUTE FOR GENOMIC MEDICINE (IIGM), ITALY SIMON FRASER UNIVERSITY, CANADA INSTITUTE FOR SYSTEMS ANALYSIS AND COMPUTER SCIENCE “A. RUBERTI”, ITALY EURAC RESEARCH, ITALY RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT, GERMANY UNIV OXFORD, UK FUKUSHIMA MEDICAL UNIVERSITY, JAPAN UNIV CALIFORNIA, USA THE UNIV QUEENSLAND, AUSTRALIA BABRAHAM INSTITUTE, UK UNIV BONN, GERMANY UNIVERSIDAD AUTONOMA DE MADRID, SPAIN ST JUDE CHILDREN'S RESEARCH HOSPITAL, USA CHANG GUNG UNIV COLLEGE OF MEDICINE AND CHANG GUNG MEMORIAL HOSPITAL, TAIWAN CHINA PHARMACEUTICAL UNIVERSITY, CHINA UNIV CALIFORNIA LOS ANGELES, USA DEPARTMENT OF BIOINFORMATICS, CHINA UNIV MICHIGAN, USA SHANGHAI NINTH PEOPLE'S HOSPITAL, CHINA TEXAS A&M COLLEGE OF DENTISTRY, USA THIRD MILITARY MEDICAL UNIV CHINA, CHINA SOOCHOW UNIVERSITY, CHINA CAS CENTER FOR EXCELLENCE IN NANOSCIENCE, CHINA CHINA AGRICULTURAL UNIVERSITY, CHINA SOOCHOW UNIVERSITY, CHINA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES, CHINA SHANXI AGRICULTURAL UNIVERSITY, CHINA SICHUAN UNIVERSITY, CHINA HUNAN KEY LABORATORY OF MEDICAL EPIGENOMICS, CHINA THE CHINESE UNIV HONG KONG, CHINA FOURTH MILITARY MEDICAL 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UNIV PENNSYLVANIA, USA AFFILIATED CANCER HOSPITAL AND INSTITUTE OF GUANGZHOU MEDICAL UNIVERSITY, CHINA WASHINGTON UNIV SCHOOL OF MEDICINE, USA UNIV BONN, GERMANY UNIV HOSPITAL RWTH AACHEN, GERMANY UNIV OF PITTSBURGH AND PITTSBURGH VA HEALTHSYSTEM, USA SPENCER CENTER FOR VISION RESEARCH, USA GEORG AUGUST UNIV GOTTINGEN, GERMANY HARVARD MEDICAL SCHOOL AND BRIGHAM & WOMEN'S HOSPITAL, USA UNIV NOTTINGHAM, UK UNIV CALIF SAN DIEGO, USA AMSTERDAM UNIV MEDICAL CENTERS, NETHERLANDS QUADRAM INSTITUTE BIOSCIENCE, UK UNIV EDINBURGH, UK HEINRICH-HEINE-UNIVERSITAT DUSSELDORF INSTITUT FUR PHYSIKALISCHE BIOLOGIE, GERMANY QUEENSLAND UNIV TECHNOLOGY, AUSTRALIA UNIV ROYAL HOLLOWAY LONDON, UK NATIONAL INSTITUTES OF HEALTH, USA UNIV NEBRASKA-LINCOLN, USA UNIV ERLANGEN NURNBERG, GERMANY UNIV TORONTO, CANADA DEPARTMENT OF OBSTETRICS AND GYNECOLOGY, USA MFP CNRS UMR 5234, FRANCE INSTITUT PASTEUR, FRANCE NATIONAL UNIV SINGAPORE, SINGAPORE SCHOOL OF MEDICINE, CHINA KANAZAWA UNIVERSITY, JAPAN UNIV ZURICH, ZURICH SOUTHWEST MEDICAL UNIVERSITY, CHINA UNIV CALIFORNIA SAN DIEGO, USA UNIV MARYLAND SCHOOL OF MEDICINE, USA NHRI, TAIWAN UNIV NORTH DAKOTA, USA SOOCHOW UNIVERSITY, CHINA FIRST AFFILIATED HOSPITAL OF XI'AN JIAOTONG UNIV SCHOOL OF MEDICINE, CHINA ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL, CHINA UNIV KANSAS, USA ZHEJIANG UNIV SCHOOL OF MEDICINE, CHINA THE BROAD INSTITUTE OF HARVARD AND MIT, USA ZHEJIANG UNIVERSITY, CHINA SHENZHEN UNIVERSITY, CHINA THE UNIV HONG KONG, CHINA WUHAN UNIVERSITY, CHINA SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE, CHINA FRIEDRICH-ALEXANDER UNIV ERLANGEN-NURNBERG, ERLANGEN GERMANY RESEARCH DEPARTMENT, SINGAPORE SOUTHERN UNIV SCIENCE AND TECHNOLOGY, CHINA SICHUAN UNIVERSITY, CHINA UNIV ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA, CHINA WENZHOU MEDICAL UNIVERSITY, CHINA QUEENSLAND UNIV TECHNOLOGY, AUSTRALIA SUN YAT-SEN UNIVERSITY, CHINA SOUTH CHINA AGRICULTURAL UNIVERSITY, CHINA SOUTHWEST HOSPITAL, CHINA UNIV ALABAMA AT BIRMINGHAM, USA GEORGIA STATE UNIVERSITY, USA BIOMEDICAL RESEARCH FOUNDATION OF THE ACADEMY OF ATHENS (BRFAA), GREECE SHANGHAI SIXTH PEOPLE'S HOSPITAL, CHINA INSTITUTE OF NEUROSCIENCES AND DEPARTMENT OF NEUROLOGY OF THE SECOND AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIVERSITY, CHINA JINAN UNIVERSITY, CHINA YANGZHOU UNIVERSITY, CHINA KYOTO INSTITUTE OF TECHNOLOGY, JAPAN EHIME UNIV GRADUATE SCHOOL OF MEDICINE, JAPAN COLUMBIA UNIVERSITY, USA JUNTENDO UNIV SCHOOL OF MEDICINE, JAPAN INDIANA UNIV SCHOOL OF MEDICINE, USA NATIONAL CHENG KUNG UNIVERSITY, TAIWAN UNIV VIRGINIA, USA ASAHIKAWA MEDICAL UNIVERSITY, JAPAN HONG KONG BAPTIST UNIVERSITY, CHINA NATHAN KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH, USA UNIV WISCONSIN-MADISON, USA CHINESE ACADEMY OF SCIENCES, CHINA CAPITAL MEDICAL UNIVERSITY, CHINA UNIV KENTUCKY, USA UNIV ALABAMA AT BIRMINGHAM, USA UNIV IOWA CARVER COLLEGE OF MEDICINE, USA THE FOURTH MILITARY MEDICAL UNIVERSITY, CHINA SHANDONG CANCER HOSPITAL AND INSTITUTE, CHINA TAIPEI MEDICAL UNIVERSITY, TAIWAN THE FOURTH MILITARY MEDICAL UNIVERSITY, CHINA CHUNG SHAN MEDICAL UNIVERSITY, TAIWAN JIANGSU UNIVERSITY, CHINA YALE UNIV SCHOOL OF MEDICINE, USA JINAN UNIVERSITY, CHINA HANGZHOU NORMAL UNIVERSITY, CHINA UNIV SOUTHEAST, CHINA UNIV MELBOURNE, AUSTRALIA CHINESE UNIV HONG KONG, CHINA FOURTH MEDICAL CENTER OF THE CHINESE PLA GENERAL HOSPITAL, CHINA DUKE-NUS MEDICAL SCHOOL, SINGAPORE ZHEJIANG UNIV SCHOOL OF MEDICINE, CHINA SHANDONG AGRICULTURAL UNIVERSITY, CHINA ZHEJIANG UNIVERSITY, CHINA SOOCHOW UNIVERSITY, CHINA THE UNIV BRITISH COLUMBIA, CANADA DONG-A UNIV COLLEGE OF MEDICINE, KOREA THE JIKEI UNIV SCHOOL OF MEDICINE, JAPAN ETH ZURICH, SWITZERLAND TABRIZ UNIV MEDICAL SCIENCES, IRAN HWA CHONG INSTITUTION, SINGAPORE TIANJIN UNIV TRADITIONAL CHINESE MEDICINE, CHINA TEMPLE UNIVERSITY, USA THE CHINESE UNIV HONG KONG, CHINA TSINGHUA UNIVERSITY, CHINA HEPATOBILIARY SECTION, TAIWAN UNIV TORONTO, CANADA AIR FORCE MEDICAL UNIVERSITY, CHINA INTERDISCIPLINARY RESEARCH CENTER ON BIOLOGY AND CHEMISTRY, USA CENTRAL SOUTH UNIVERSITY, CHINA KAOHSIUNG MEDICAL UNIVERSITY, TAIWAN FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY, CHINA BEIJING INSTITUTE OF BASIC MEDICAL SCIENCES, CHINA CITY UNIV HONG KONG, CHINA ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, USA GRADUATE SCHOOL OF DONG-A UNIVERSITY, KOREA CENTRE FOR GENOMIC REGULATION (CRG), ESPAÑA LABORATORY OF PAIN AND SIGNALING, USA UNIV BRESCIA, ITALY UNIV TEXAS SOUTHWESTERN MEDICAL CENTER, USA CANCER RESEARCH UK BEATSON INSTITUTE, UK UNIV CALIFORNIA, USA TABRIZ UNIV MEDICAL SCIENCES, IRAN UNIV MONASTIR, TUNISIA UNIV VIRGINIA, USA BOSTON UNIVERSITY, USA UNIV ARIZONA, USA PEKING UNIV FIRST HOSPITAL, CHINA CHINESE ACADEMY OF SCIENCES, CHINA ZHEJIANG UNIV SCHOOL OF MEDICINE, CHINA UNIV SCIENCE & TECHNOLOGY OF CHINA, CHINA RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL, USA THOMAS JEFFERSON UNIVERSITY/VICKIE & JACK FARBER INSTITUTE FOR NEUROSCIENCE, USA SOOCHOW UNIVERSITY, CHINA PEOPLE'S HOSPITAL OF HANGZHOU MEDICAL COLLEGE, CHINA UNIV ALABAMA AT BIRMINGHAM, USA SCHOOL OF RADIATION MEDICINE AND PROTECTION AND STATE KEY LABORATORY OF RADIATION MEDICINE AND PROTECTION, CHINA THE CHINESE UNIV HONG KONG, CHINA HUAZHONG AGRICULTURAL UNIVERSITY, CHINA HENAN UNIV TECHNOLOGY, CHINA UNIV UTAH, USA THE UNIV TEXAS HEALTH SCIENCE CENTER AT HOUSTON (UTHEALTH), USA WAKE FOREST BAPTIST COMPREHENSIVE CANCER CENTER, USA HUNGARIAN ACADEMY OF SCIENCES, HUNGARY THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN'S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY, CHINA COLLEGE OF RESPIRATORY AND CRITICAL CARE MEDICINE, CHINA UNIV NEWCASTLE, AUSTRALIA UNIV HOUSTON, USA UNIV MARYLAND, USA EAST CHINA NORMAL UNIVERSITY, CHINA NANJING AGRICULTURAL UNIVERSITY, CHINA DEPARTMENT OF PHYSIOLOGY, USA RUTGERS UNIVERSITY, USA NANJING UNIV CHINESE MEDICINE, CHINA CENTRAL CHINA NORMAL UNIVERSITY, CHINA THE FOURTH MILITARY MEDICAL UNIVERSITY, CHINA THE FOURTH MILITARY MEDICAL UNIVERSITY, CHINA BEIJING ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES, CHINA SHANDONG UNIVERSITY, CHINA PEKING UNIV HEALTH SCIENCES CENTER, CHINA ZHEJIANG UNIVERSITY, CHINA BEIJING INSTITUTE OF GENOMICS, CHINA UNIV SYDNEY, AUSTRALIA SHENZHEN UNIVERSITY, CHINA WUHAN UNIVERSITY, CHINA UNIV CALGARY, CANADA CHILDREN’S HOSPITAL MEDICAL CENTER, USA CHINA PHARMACEUTICAL UNIVERSITY, CHINA KAROLINSKA INSTITUTET DIVISION OF TOXICOLOGY, RUSSIA KEY LABORATORY OF CELL DIFFERENTIATION AND APOPTOSIS OF CHINESE MINISTRY OF EDUCATION, CHINA SOUTHWEST MEDICAL UNIVERSITY, CHINA MASSACHUSETTS GENERAL HOSPITAL, USA CHINESE PEOPLE'S LIBERATION ARMY GENERAL HOSPITAL, CHINA THIRD MILITARY MEDICAL UNIVERSITY, CHINA HUAZHONG AGRICULTURAL UNIVERSITY, CHINA ZHEJIANG UNIVERSITY, CHINA GUANGXI MEDICAL UNIVERSITY, CHINA ZHEJIANG UNIVERSITY, CHINA THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN'S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY, CHINA CHINESE ACADEMY OF SCIENCES, CHINA QUEENSLAND UNIV TECHNOLOGY, AUSTRALIA TEXAS A&M UNIVERSITY, USA SOOCHOW UNIVERSITY, CHINA ZHEJIANG UNIV SCHOOL OF MEDICINE, CHINA UNIV AT BUFFALO, USA ZHENGZHOU UNIVERSITY, SWEDEN NANJING MEDICAL UNIVERSITY, CHINA UNIV KENTUCKY, USA SHANGHAI JIAO TONG UNIVERSITY, CHINA THE OHIO STATE UNIVERSITY, USA SHENZHEN UNIV MEDICAL SCHOOL, CHINA STATE KEY LABORATORY OF MEDICINAL CHEMICAL BIOLOGY, CHINA UNIV CALIFORNIA, USA UNIV MEDICAL CENTER OF JOHANNES GUTENBERG-UNIVERSITY, GERMANY UNIV PADOVA, ITALY RUTGERS UNIVERSITY, USA MOSCOW STATE UNIVERSITY, RUSSIA UNIV MICHIGAN, USA INSTITUTE OF LIFE SCIENCES, CHINA THE UNIV QUEENSLAND, AUSTRALIA UNIV INNSBRUCK, AUSTRIA INDIANA UNIV SCHOOL OF MEDICINE, USA SWEDISH UNIV AGRICULTURAL SCIENCES, SWEDEN SOUTHERN MEDICAL UNIVERSITY, CHINA LOVELACE RESPIRATORY RESEARCH INSTITUTE, USA TOKYO MEDICAL AND DENTAL UNIV (TMDU), JAPAN HUAZHONG UNIV SCIENCE AND TECHNOLOGY, CHINA MAASTRICHT UNIV MEDICAL CENTER, UK DEPARTMENT OF MOLECULAR MICROBIOLOGY, USA HONG KONG BAPTIST UNIVERSITY, CHINA HONG KONG BAPTIST UNIVERSITY, CHINA SI LA TREMBLADE NANTES SE PDG-RBE-SGMM-LGPMM PDG-RBE IN WOS Ifremer UPR copubli-france copubli-p187 copubli-europe copubli-univ-france copubli-int-hors-europe copubli-sud IF 13.391 TC 875 UR https://archimer.ifremer.fr/doc/00688/79984/83003.pdf LA English DT Article DE ;Autophagosome;cance;rflux;LC3;lysosome;macroautophagy;neurodegeneration;phagophore;stress;vacuole AB In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field. PY 2021 PD JAN SO Autophagy SN 1554-8627 PU Informa UK Limited VL 17 IS 1 UT 000636121800001 BP 1 EP 382 DI 10.1080/15548627.2020.1797280 ID 79984 ER EF