FN Archimer Export Format
PT J
TI Newly identified proviruses in Thermotogota suggest that viruses are the vehicles on the highways of interphylum gene sharing
BT 
AF Haverkamp, Thomas H. A.
   Lossouarn, Julien
   Zhaxybayeva, Olga
   Lyu, Jie
   Bienvenu, Nadège
   Geslin, Claire
   Nesbø, Camilla L.
AS 1:1;2:2;3:3;4:4;5:4;6:4;7:5,6;
FF 1:;2:;3:;4:;5:;6:;7:;
C1 Centre for Ecological and Evolutionary Synthesis, Department of Biosciences University of Oslo Oslo ,Norway
   Université Paris‐Saclay, INRAE, AgroParisTech, Micalis Institute Jouy‐en‐Josas 78350, France
   Department of Biological Sciences Dartmouth College Hanover NH ,USA
   Université Brest, CNRS, IFREMER,, Laboratoire de Microbiologie des Environnements Extrêmes, Plouzané F‐29280 ,France
   Department of Biological Sciences University of Alberta Edmonton AB ,Canada
   Department of Chemical Engineering and Applied Chemistry University of Toronto Toronto ON M5S 3E5, Canada
C2 UNIV OSLO, NORWAY
   UNIV PARIS SACLAY, FRANCE
   DARTMOUTH COLL, USA
   UBO, FRANCE
   UNIV ALBERTA, CANADA
   UNIV TORONTO, CANADA
UM BEEP-LM2E
IN WOS Cotutelle UMR
   copubli-france
   copubli-europe
   copubli-univ-france
   copubli-int-hors-europe
IF 5.476
TC 3
UR https://archimer.ifremer.fr/doc/00720/83169/88439.pdf
LA English
DT Article
AB Phylogenomic analyses of bacteria from the phylum Thermotogota have shown extensive lateral gene transfer with distantly related organisms, particularly with Firmicutes. One likely mechanism of such DNA transfer is viruses. However, to date, only three temperate viruses have been characterized in this phylum, all infecting bacteria from the Marinitoga genus. Here we report 17 proviruses integrated into genomes of bacteria belonging to eight Thermotogota genera and induce viral particle production from one of the proviruses. All except an incomplete provirus from Mesotoga fall into two groups based on sequence similarity, gene synteny and taxonomic classification. Proviruses of Group 1 are found in the genera Geotoga, Kosmotoga, Marinitoga, Thermosipho and Mesoaciditoga and are similar to the previously characterized Marinitoga viruses, while proviruses from Group 2 are distantly related to the Group 1 proviruses, have different genome organization and are found in Petrotoga and Defluviitoga. Genes carried by both groups are closely related to Firmicutes and Firmicutes (pro)viruses in phylogenetic analyses. Moreover, one of the groups show evidence of recent gene exchange and may be capable of infecting cells from both phyla. We hypothesize that viruses are responsible for a large portion of the observed gene flow between Firmicutes and Thermotogota. 
PY 2021
PD NOV
SO Environmental Microbiology
SN 1462-2912
PU Wiley
VL 23
IS 11
UT 000688929900001
BP 7105
EP 7120
DI 10.1111/1462-2920.15723
ID 83169
ER

EF