FN Archimer Export Format PT J TI Effect of culture supernatant from Haslea ostrearia on the clearance rate and survival rate of adult Pacific oyster Crassostrea gigas infected with Vibrio aestuarianus BT AF Prasetiya, Fiddy S. Arsad, Sulastri Astuty, Sri Agung, 1Mochamad U. K. STAVRAKAKIS, Christophe Mouget, Jean-Luc AS 1:1,2;2:3;3:1;4:1;5:1;6:4;7:5; FF 1:;2:;3:;4:;5:;6:PDG-RBE-SGMM;7:; C1 Department of Marine Science, Faculty of Fisheries and Marine Sciences, Padjadjaran University, Sumedang, West Java, Indonesia Research Center of Molecular Biotechnology and Bioinformatics, Padjadjaran University, Bandung, West Java, Indonesia Study Programme of Aquatic Resources Management, Faculty of Fisheries and Marine Sciences, University of Brawijaya, Malang, Indonesia L’Institut Français de Recherche pour l’Exploitation de la Mer, Unité Santé, Génétique et Microbiologie des Mollusques marins, Plateforme expérimentale Mollusques Marins de Bouin (IFREMER) Station de Bouin, Bouin, France FR CNRS 3473 IUML, Mer-Molécules-Santé (MMS), Le Mans Université, Le Mans, France C2 UNIV PADJAJARAN, INDONESIA UNIV PADJAJARAN, INDONESIA UNIV BRAWIJAYA, INDONESIA IFREMER, FRANCE UNIV LE MANS, FRANCE SI BOUIN SE PDG-RBE-SGMM TC 0 UR https://archimer.ifremer.fr/doc/00720/83183/88120.pdf LA English DT Article AB The microalga Haslea ostrearia is known as a diatom with the peculiarity of producing a water soluble blue-green pigment called marennine. This pigment has antibacterial activities against pathogenic bacteria of bivalves produced in aquaculture. The present study evaluates the effect of culture supernatant of the diatom Haslea ostrearia containing marennine on the clearance rate (CR) and survival rate (SR) of adult Pacific oyster Crassostrea gigas infected with the bacterial pathogen Vibrio aestuarianus. The greening of oysters was conducted by exposing bivalves to 0.5 mg L-1 of marennine for three days, and the effect of marennine on the CR and SR of oysters was evaluated by comparing four groups of treatment: control, greened, control+infected and greened+infected. The SR of oysters in each treatment was monitored for 11 days. Our results showed that marennine concentration decreased with time and dropped significantly on the last day of greening, and that marennine at an initial concentration of 0.5 mg L-1 did not significantly affect the CR of oysters in all treatments. Mortality of oysters was only observed in the control+infected group, but it was not significantly different from the control. Hence, the present study showed that the greening using 0.5 mg L-1 of marennine did not affect SR of adult oyster C. gigas, but further studies are needed to determine whether H. ostrearia supernatant could be used as an antibacterial and prophylactic agent in bivalve aquaculture PY 2021 SO AACL Bioflux SN 1844-9166 PU International Journal of the Bioflux Society VL 14 IS 4 BP 2050 EP 2060 ID 83183 ER EF