FN Archimer Export Format
PT J
TI Acute and chronic toxicity assessments of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) on the calanoid copepod Acartia clausi: Effects on survival, development, sex-ratio and reproduction
BT 
AF Djebbi, Emna
   Néjib Daly Yahia, Mohamed
   Farcy, Emilie
   Pringault, Olivier
   Bonnet, Delphine
AS 1:1;2:2;3:3;4:4;5:3;
FF 1:;2:;3:;4:;5:;
C1 Faculty of Sciences of Bizerte, Carthage University, 7021, Zarzouna, LR18ES41 (Tunis El Manar University), 1082 Tunis, Tunisia
   Department of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, PO Box 2713, Doha, Qatar
   Université de Montpellier, CNRS, Ifremer, IRD, MARBEC, Montpellier, France
   Aix Marseille University, Université de Toulon, CNRS, IRD, MIO UM 110, 13288 Marseille, France
C2 UNIV CARTHAGE, TUNISIA
   UNIV QATAR, QATAR
   UNIV MONTPELLIER, FRANCE
   UNIV AIX MARSEILLE, FRANCE
UM MARBEC
IN WOS Cotutelle UMR
   copubli-france
   copubli-univ-france
   copubli-int-hors-europe
   copubli-sud
IF 9.8
TC 14
UR https://archimer.ifremer.fr/doc/00728/83966/88899.pdf
LA English
DT Article
DE ;Estrogens;Low concentration effect;Lethal effect;Life cycle;Egg hatching success;Lifespan
AB Estrogens, such as the 17β-estradiol (E2) and the 17α-ethinylestradiol (EE2), have been regarded as a global threat to aquatic ecosystems due to their pseudo-persistence, their high estrogenic activity and their toxicity towards non-target species. Data regarding their ecotoxicological effects on marine calanoid copepods are very scarce. In this study, the calanoid copepod Acartia clausi was used as a model organism for estrogens exposure in marine pelagic ecosystems. Lethal effects of estrogens on A. clausi life-stages (Embryos, one day old nauplii: N1, three day old nauplii: N3, copepodites: C1-C3 and adults: C6) were investigated using 48 h acute tests. Copepods showed stage-specific responses against E2 and EE2 acute exposure. The most resistant life stage was N1 with LC50 values > 1500 μg L-1 and >5000 μg L-1, respectively for E2 and EE2. For N3, C1-C3, and C6, sensitivity to estrogens decreased with age and survival was affected at concentrations above those detected in the environment reflecting low estrogens acute toxicity for these life stages. In contrast, embryonic stage revealed high vulnerability to E2 and EE2 acute effects. Embryos showed non-monotonic dose-response and hatching success was significantly reduced at low realistic concentrations of E2 (0.005, 0.5, and 5 μg L-1) and EE2 (0.05 and 5 μg L-1). Survival, development and sex ratio of A. clausi to EE2 exposure at 1 and 100 μg L-1 were also determined during a life cycle experiment. Fitness of the females of the generation F0 was evaluated by measuring lifespan, prosome length and egg production. The main observed effects were the decrease of females’ prosome length, the feminization of the population and the reduction of the egg production for the generation F0 at 100 μg L-1 of EE2. This concentration is above those reported in the environment indicating the tolerance of A. clausi to EE2 at environmentally relevant concentrations. 
PY 2022
PD FEB
SO Science Of The Total Environment
SN 0048-9697
PU Elsevier BV
VL 807
IS Part 2
UT 000711161700002
DI 10.1016/j.scitotenv.2021.150845
ID 83966
ER

EF