FN Archimer Export Format
PT J
TI Revisiting tolerance to ocean acidification: insights from a new framework combining physiological and molecular tipping points of Pacific oyster
BT 
AF Lutier, Mathieu
   DI POI BROUSSARD, Carole
   Gazeau, Frédéric
   Appolis, Alexis
   Le Luyer, Jeremy
   Pernet, Fabrice
AS 1:1;2:4;3:2;4:4;5:3;6:1;
FF 1:PDG-RBE-PFOM-LPI;2:PDG-RBE-PFOM-LPI;3:;4:;5:PDG-RBE-RMPF;6:PDG-RBE-PFOM-LPI;
C1 LEMAR CNRS/UBO/IRD/Ifremer, ZI pointe du diable, CS 10070 F‐29280 Plouzané , France
   LOV Sorbonne Université, CNRS, Laboratoire d'Océanographie de Villefranche, Villefranche‐sur‐Mer ,France
   EIO UPF/IRD/ILM/Ifremer, Labex CORAIL, Unité RMPF, Centre Océanologique du Pacifique, Vairao – BP 49 Vairao, Tahiti, Polynésie française
   LEMAR CNRS/UBO/IRD/Ifremer, ZI pointe du diable, CS 10070 F‐29280 Plouzané , France
C2 IFREMER, FRANCE
   UNIV SORBONNE, FRANCE
   IFREMER, FRANCE
   UBO, FRANCE
SI BREST
   ARGENTON
   TAHITI
SE PDG-RBE-PFOM-LPI
   PDG-RBE-RMPF
UM LEMAR
   EIO
IN WOS Ifremer UMR
   WOS Cotutelle UMR
   copubli-france
   copubli-univ-france
IF 11.6
TC 14
UR https://archimer.ifremer.fr/doc/00749/86130/91363.pdf
   https://archimer.ifremer.fr/doc/00749/86130/91364.docx
   https://archimer.ifremer.fr/doc/00749/86130/91365.xlsx
LA English
DT Article
DE ;acidification;lipidomic;mollusk;reaction norm;threshold;transcriptomic
AB Studies on the impact of ocean acidification on marine organisms involve exposing organisms to future acidification scenarios which has limited relevance for coastal calcifiers living in a mosaic of habitats. Identification of tipping points beyond which detrimental effects are observed is a widely generalizable proxy of acidification susceptibility at the populational level. This approach is limited to a handful of studies that focus on only a few macro-physiological traits, thus overlooking the whole organism response. Here we develop a framework to analyze the broad macro-physiological and molecular responses over a wide pH range in juvenile oyster. We identify low tipping points for physiological traits at pH 7.3-6.9 that coincide with a major reshuffling in membrane lipids and transcriptome. In contrast, a drop in pH affects shell parameters above tipping points, likely impacting animal fitness. These findings were made possible by the development of an innovative methodology to synthesize and identify the main patterns of variations in large -omic datasets, fitting them to pH and identifying molecular tipping-points. We propose the broad application of our framework to the assessment of effects of global change on other organisms. 
PY 2022
PD MAY
SO Global Change Biology
SN 1354-1013
PU Wiley
VL 28
IS 10
UT 000757423000001
BP 3333
EP 3348
DI 10.1111/gcb.16101
ID 86130
ER

EF