FN Archimer Export Format
PT J
TI Seaweeds influence oyster microbiota and disease susceptibility
BT 
AF Dugeny, Elyne
   DE LORGERIL, Julien
   Petton, Bruno
   Toulza, Eve
   Gueguen, Yannick
   Pernet, Fabrice
AS 1:1;2:2;3:1;4:3;5:2;6:1;7:;
FF 1:PDG-RBE-PFOM-LPI;2:PDG-RBE-IHPE;3:PDG-RBE-PFOM-LPI;4:;5:PDG-RBE-IHPE;6:PDG-RBE-PFOM-LPI;7:;
C1 Université de Brest, Ifremer, CNRS, IRD, LEMAR Plouzané, France
   IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia Montpellier ,France
   IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia Montpellier ,France
C2 IFREMER, FRANCE
   IFREMER, FRANCE
   UNIV PERPIGNAN, FRANCE
SI BREST
   MONTPELLIER
   ARGENTON
SE PDG-RBE-PFOM-LPI
   PDG-RBE-IHPE
UM LEMAR
   IHPE
IN WOS Ifremer UMR
   WOS Cotutelle UMR
   copubli-france
   copubli-univ-france
IF 4.8
TC 2
UR https://archimer.ifremer.fr/doc/00750/86228/91556.pdf
LA English
DT Article
DE ;bivalve;disease ecology;epidemiology;macroalgae;microbiome;pathogen
AB A growing awareness of role that microbiota can play in mediating the effects of pathogens on hosts has given rise to the concept of the pathobiome. Recently, we demonstrated that the Pacific oyster mortality syndrome affecting Crassostrea gigas oysters is caused by infection with the Ostreid herpesvirus type 1 (OsHV-1) followed by infection with multiple bacterial taxa. Here we extend the concept of this pathobiome beyond the host species and its bacterial microbiota by investigating how seaweed living in association with oysters influences their response to the disease. We hypothesized that by their mere presence in the environment, different species of seaweeds can positively or negatively influence the risk of disease in oysters by shaping their bacterial microbiota and their immune response. Although seaweed and oysters do not have direct ecological interactions, they are connected by seawater and likely share microbes. To test our hypothesis, oysters were acclimated with green, brown or red algae for 2 weeks and then challenged with OsHV-1. We monitored host survival and pathogen proliferation and performed bacterial microbiota and transcriptome analyses. We found that seaweeds can alter the bacterial microbiota of the host and its response to the disease. More particularly, green algae belonging to the genus Ulva spp. induced bacterial microbiota dysbiosis in oyster and modification of its transcriptional immune response leading to increased susceptibility to the disease. This work provides a better understanding of a marine disease and highlights the importance of considering both macrobiotic and microbiotic interactions for conservation, management and exploitation of marine ecosystems and resources. 
PY 2022
PD APR
SO Journal Of Animal Ecology
SN 0021-8790
PU Wiley
VL 91
IS 4
UT 000761856600001
BP 805
EP 818
DI 10.1111/1365-2656.13662
ID 86228
ER

EF