FN Archimer Export Format
PT J
TI Strong parallel differential gene expression induced by hatchery rearing weakly associated with methylation signals in adult Coho Salmon ( O. kisutch )
BT 
AF Leitwein, Maeva
   Wellband, Kyle
   Cayuela, Hugo
   Le Luyer, Jeremy
   Mohns, Kayla
   Withler, Ruth
   Bernatchez, Louis
AS 1:1,2;2:1,3;3:1,4,5;4:6;5:7;6:7;7:1;
FF 1:PDG-RBE-MARBEC-LAAAS;2:;3:;4:PDG-RBE-RMPF;5:;6:;7:;
C1 Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada, G1V 0A6
   Centre pour la Biodiversité Marine, l’exploitation et la Conservation, Université de Montpellier, Centre National de la Recherche Scientifique, Ifremer, Institut de Recherche pour le Développement, Palavas-les-Flots, France
   Fisheries and Oceans Canada, Pacific Science Enterprise Centre, West Vancouver, British Columbia, Canada, V7V 1N6
   Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland
   Université Lyon 1, CNRS, UMR 5558, Laboratoire de Biométrie et Biologie Evolutive, F-769622, Villeurbanne, France
   Ifremer, UMR 241 Ecosystèmes Insulaires Océaniens, Centre Ifremer du Pacifique, BP 49, 98719 Tahiti, Polynésie française
   Department of Fisheries and Oceans Canada, Pacific Biological Station, Nanaimo, British Columbia, Canada, V9T 6N7
C2 UNIV LAVAL, CANADA
   IFREMER, FRANCE
   MPO, CANADA
   UNIV LAUSANNE, SWITZERLAND
   UNIV LYON, FRANCE
   IFREMER, FRANCE
   MPO, CANADA
SI PALAVAS
   TAHITI
SE PDG-RBE-MARBEC-LAAAS
   PDG-RBE-RMPF
UM MARBEC
   EIO
IN WOS Ifremer UMR
   DOAJ
   copubli-france
   copubli-univ-france
   copubli-int-hors-europe
IF 3.3
TC 5
UR https://archimer.ifremer.fr/doc/00755/86686/92132.pdf
   https://archimer.ifremer.fr/doc/00755/86686/92133.zip
   https://archimer.ifremer.fr/doc/00755/86686/97701.pdf
LA English
DT Article
DE ;gene expression;epigenomic;hatchery;conservation;fitness;salmonid
AB Human activities and resource exploitation led to a massive decline of wild salmonid populations, consequently numerous conservation programs have been developed to supplement wild populations. However, many studies documented reduced fitness of hatchery-born relative to wild fish. Here, by using both RNA sequencing and Whole Genome Bisulfite Sequencing (WGBS), we show that of hatchery and wild born adult Coho Salmon (Oncorhynchus kisutch) originating from two previously studied river systems, early-life hatchery rearing environment induced significant and parallel gene expression differentiation is maintained until Coho come back to their natal river for reproduction. A total of 3,643 genes differentially expressed and 859 co-expressed genes were down-regulated in parallel in hatchery born fish from both rivers relative to their wild congeners. Among those genes, 26 displayed a significant relationship between gene expression and the median gene body methylation and 669 single CpG displayed a significant correlation between methylation level and the associated gene expression. The link between methylation and gene expression was weak suggesting that DNA methylation is not the only player in mediating hatchery-related expression differences. Yet, significant gene expression differentiation was observed despite 18 month spent in a common environment (i.e. the sea). Finally, the differentiation is observed in parallel in two different river system, highlighting the fact that early life environment may account for at least some of the reduced fitness of the hatchery salmon in the wild. These results illustrate the relevance and importance of considering both epigenome and transcriptome to evaluate the costs and benefits of large-scale supplementation programs. 
PY 2022
PD APR
SO Genome Biology And Evolution
SN 1759-6653
PU Oxford University Press (OUP)
VL 14
IS 4
UT 000779884700005
DI 10.1093/gbe/evac036
ID 86686
ER

EF