FN Archimer Export Format
PT J
TI Telomere dynamics in female Columbian ground squirrels: recovery after emergence and loss after reproduction
BT 
AF Viblanc, Vincent A.
   Criscuolo, François
   Sosa, Sebastian
   Schull, Quentin
   Boonstra, Rudy
   Saraux, Claire
   Lejeune, Mathilde
   Roth, Jeffrey D.
   Uhlrich, Pierre
   Zahn, Sandrine
   Dobson, F. Stephen
AS 1:1;2:1;3:1;4:2;5:3;6:1;7:1;8:4;9:1;10:1;11:1,4;
FF 1:;2:;3:;4:;5:;6:;7:;8:;9:;10:;11:;
C1 Université de Strasbourg, CNRS, IPHC UMR 7178, 67000, Strasbourg, France
   MARBEC, University of Montpellier, IFREMER, IRD, CNRS, Avenue Jean Monnet CS 30171, 34203, Sète, France
   Department of Biological Sciences, University of Toronto, Scarborough, ON, M1C 1A4, Canada
   Department of Biological Sciences, Auburn University, Auburn, AL, USA
C2 CNRS, FRANCE
   MARBEC, University of Montpellier, IFREMER, IRD, CNRS, Avenue Jean Monnet CS 30171, 34203, Sète, France
   UNIV TORONTO, CANADA
   UNIV AUBURN, USA
IF 2.7
TC 5
UR https://archimer.ifremer.fr/doc/00777/88921/99939.pdf
LA English
DT Article
DE ;Aging;Telomeres;Cost of reproduction;Hibernation;Telomerase;Stress;Reproduction;Mammals
AB Telomeres are specialized non-coding DNA sequences located at the end of chromosomes and that protect genetic information. Telomere loss over lifespan is generally viewed as a phenomenon associated with aging in animals. Recently, telomere elongation after hibernation has been described in several mammals. Whether this pattern is an adaptation to repair DNA damage caused during rewarming from torpor or if it coevolved as a mechanism to promote somatic maintenance in preparation for the upcoming reproductive effort remains unclear. In a longitudinal study measuring telomere length using buccal swabs, we tested if telomere elongation was related to reproductive success in wild adult female Columbian ground squirrels (Urocitellus columbianus) that were monitored from emergence from hibernation to the end of the reproductive season. We found three key results. First, female telomere length increased at the start of the breeding season, both in breeding and non-breeding individuals. Second, post-emergence telomere lengthening was unrelated to female future reproductive output. Third, telomere length decreased in breeding females during lactation, but remained stable in non-breeding females over a similar period. Within breeders, telomeres shortened more in females producing larger and heavier litters. We concluded that telomere lengthening after hibernation did not constrain immediate female reproductive capacities. It was more likely to be part of the body recovery process that takes place after hibernation. Telomere erosion that occurs after birth may constitute a physiological cost of female reproduction. 
PY 2022
PD JUL
SO Oecologia
SN 0029-8549
PU Springer Science and Business Media LLC
VL 199
IS 2
UT 000812453100001
BP 301
EP 312
DI 10.1007/s00442-022-05194-9
ID 88921
ER

EF