FN Archimer Export Format
PT J
TI Phage–host coevolution in natural populations
BT 
AF Piel, Damien
   Bruto, Maxime
   Labreuche, Yannick
   Blanquart, François
   Goudenège, David
   Barcia-Cruz, Rubén
   Chenivesse, Sabine
   Le Panse, Sophie
   James, Adele
   Dubert, Javier
   Petton, Bruno
   Lieberman, Erica
   Wegner, K. Mathias
   Hussain, Fatima A.
   Kauffman, Kathryn M.
   Polz, Martin F.
   Bikard, David
   Gandon, Sylvain
   Rocha, Eduardo P. C.
   Le Roux, Frederique
AS 1:1,2;2:2;3:1,2;4:3,4;5:1,2;6:2,5;7:2;8:2;9:1;10:2,5,6;11:1;12:7;13:8;14:6;15:6;16:6,9;17:10;18:11;19:12;20:1,2;
FF 1:PDG-RBE-PFOM;2:PDG-RBE-PFOM;3:PDG-RBE-PFOM;4:;5:PDG-RBE-PFOM;6:;7:;8:;9:PDG-RBE-PFOM;10:;11:PDG-RBE-PFOM-LPI;12:;13:;14:;15:;16:;17:;18:;19:;20:PDG-RBE-PFOM;
C1 Ifremer, Unité Physiologie Fonctionnelle des Organismes Marins, ZI de la Pointe du Diable, Plouzané, France
   Sorbonne Université, UPMC Paris 06, CNRS, UMR 8227, Integrative Biology of Marine Models, Station Biologique de Roscoff, Roscoff cedex, France
   Centre for Interdisciplinary Research in Biology (CIRB), Collège de France, CNRS, INSERM, PSL Research University, Paris, France
   Infection Antimicrobials Modelling Evolution, UMR 1137, INSERM, Université de Paris, Paris, France
   Department of Microbiology and Parasitology, CIBUS-Faculty of Biology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain
   Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
   Eligo Bioscience, Paris, France
   AWI - Alfred Wegener Institut - Helmholtz-Zentrum für Polar- und Meeresforschung, Coastal Ecology, Waddensea Station Sylt, List, Germany
   Division of Microbial Ecology, Centre for Microbiology and Environmental Systems Science, University of Vienna, Vienna, Austria
   Synthetic Biology Group, Department of Microbiology, Institut Pasteur, Paris, France
   CEFE (UMR 5175 CNRS - Université de Montpellier - Université Paul Valéry - EPHE), Montpellier, France
   Institut Pasteur, Université de Paris, CNRS UMR3525, Microbial Evolutionary Genomics, Paris, France
C2 IFREMER, FRANCE
   UNIV SORBONNE, FRANCE
   COLL FRANCE, FRANCE
   UNIV PARIS, FRANCE
   UNIV SANTIAGO DE COMPOSTELA, SPAIN
   MIT, USA
   ELIGO BIOSCIENCE, FRANCE
   INST A WEGENER, GERMANY
   UNIV VIENNA, AUSTRIA
   INST PASTEUR, FRANCE
   UNIV MONTPELLIER, FRANCE
   INST PASTEUR, FRANCE
SI ROSCOFF
   BREST
   ARGENTON
SE PDG-RBE-PFOM
   PDG-RBE-PFOM-LPI
UM LEMAR
IN WOS Ifremer UPR
   WOS Ifremer UMR
   copubli-france
   copubli-europe
   copubli-univ-france
   copubli-int-hors-europe
IF 28.3
TC 40
UR https://archimer.ifremer.fr/doc/00780/89208/95186.pdf
LA English
DT Article
AB Coevolution between bacteriophages (phages) and their bacterial hosts occurs through changes in resistance and counter-resistance mechanisms. To assess phage–host evolution in wild populations, we isolated 195 Vibrio crassostreae strains and 243 vibriophages during a 5-month time series from an oyster farm and combined these isolates with existing V. crassostreae and phage isolates. Cross-infection studies of 81,926 host–phage pairs delineated a modular network where phages are best at infecting co-occurring hosts, indicating local adaptation. Successful propagation of phage is restricted by the ability to adsorb to closely related bacteria and further constrained by strain-specific defence systems. These defences are highly diverse and predominantly located on mobile genetic elements, and multiple defences are active within a single genome. We further show that epigenetic and genomic modifications enable phage to adapt to bacterial defences and alter host range. Our findings reveal that the evolution of bacterial defences and phage counter-defences is underpinned by frequent genetic exchanges with, and between, mobile genetic elements. 
PY 2022
PD JUN
SO Nature Microbiology
SN 2058-5276
PU Springer Science and Business Media LLC
VL 7
IS 7
UT 000817028500005
BP 1075
EP 1086
DI 10.1038/s41564-022-01157-1
ID 89208
ER

EF