TY - JOUR T1 - Environmental microplastics disrupt swimming activity in acute exposure in Danio rerio larvae and reduce growth and reproduction success in chronic exposure in D. rerio and Oryzias melastigma A1 - Cormier,Bettie A1 - Cachot,Jerome A1 - Blanc,Melanie A1 - Cabar,Mathieu A1 - Clérandeau,Christelle A1 - Dubocq,Florian A1 - Le Bihanic,Florane A1 - Morin,Bénédicte A1 - Zapata,Sarah A1 - Bégout,Marie-Laure A1 - Cousin,Xavier AD - Bordeaux University, EPOC, UMR CNRS 5805, Avenue des Facultés, 33400, Talence, France AD - Man-Technology-Environment Research Centre, School of Science and Technology, Örebro University, Fakultetsgatan 1, 701 82, Örebro, Sweden AD - MARBEC, Univ. Montpellier, CNRS, Ifremer, IRD, INRAE, 34250, Palavas-les-flots, France AD - MARBEC, Univ. Montpellier, CNRS, Ifremer, IRD, INRAE, 34250, Palavas-les-flots, France UR - https://archimer.ifremer.fr/doc/00782/89436/ DO - 10.1016/j.envpol.2022.119721 KW - Environmental microplastics KW - Fish KW - Reprotoxicity KW - Growth and behaviour alterations KW - Biomarkers KW - Adsorbed chemicals N2 - Microplastics (MPs), widely present in aquatic ecosystems, can be ingested by numerous organisms, but their toxicity remains poorly understood. Toxicity of environmental MPs from 2 beaches located on the Guadeloupe archipelago, Marie Galante (MG) and Petit-Bourg (PB) located near the North Atlantic gyre, was evaluated. A first experiment consisted in exposing early life stages of zebrafish (Danio rerio) to MPs at 1 or 10 mg/L. The exposure of early life stages to particles in water induced no toxic effects except a decrease in larval swimming activity for both MPs exposures (MG or PB). Then, a second experiment was performed as a chronic feeding exposure over 4 months, using a freshwater fish species, zebrafish, and a marine fish species, marine medaka (Oryzias melastigma). Fish were fed with food supplemented with environmentally relevant concentrations (1% wet weight of MPs in food) of environmental MPs from both sites. Chronic feeding exposure led to growth alterations in both species exposed to either MG or PB MPs but were more pronounced in marine medaka. Ethoxyresorufin-O-deethylase (EROD) and acetylcholinesterase (AChE) activities were only altered for marine medaka. Reproductive outputs were modified following PB exposure with a 70 and 42% decrease for zebrafish and marine medaka, respectively. Offspring of both species (F1 generation) were reared to evaluate toxicity following parental exposure on unexposed larvae. For zebrafish offspring, it revealed premature mortality after parental MG exposure and parental PB exposure produced behavioural disruptions with hyperactivity of F1 unexposed larvae. This was not observed in marine medaka offspring. This study highlights the ecotoxicological consequences of short and long-term exposures to environmental microplastics relevant to coastal marine areas, which represent essential habitats for a wide range of aquatic organisms. Y1 - 2022/09 PB - Elsevier BV JF - Environmental Pollution SN - 0269-7491 VL - 308 ID - 89436 ER -